4.7 Article

Microbial metabolites as modulators of the infant gut microbiome and host-microbial interactions in early life

Related references

Note: Only part of the references are listed.
Article Gastroenterology & Hepatology

Advancing human gut microbiota research by considering gut transit time

Nicola Prochazkova et al.

Summary: Accumulating evidence indicates that gut transit time is a key factor in shaping the gut microbiota composition and activity, which are linked to human health. This review discusses the variations in whole gut and segmental transit times, the impact of these variations on the gut microbiota, and the mechanisms by which the gut microbiota may affect gut motility. It argues that considering individual differences in gut transit time can improve our understanding of diet-microbiota interactions and disease-related microbiome signatures.
Article Nutrition & Dietetics

Early-life formula feeding is associated with infant gut microbiota alterations and an increased antibiotic resistance load

Katariina M. M. Parnanen et al.

Summary: The study found that early exposure to formula is correlated with a higher neonatal ARG burden, suggesting that feeding mode should be considered by clinicians to minimize the proliferation of antibiotic-resistant gut bacteria in infants, in addition to antibiotic use during the first months of life.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)

Article Biochemical Research Methods

Point-of-care human milk testing for maternal secretor status

Saeromi Chung et al.

Summary: The study developed an electrochemical impedimetric-based biosensor for monitoring the variation in human milk oligosaccharide (HMO) composition, specifically focusing on 2'-fucosyllactose (2'FL) which is associated with infant growth and health. The sensor showed high linearity and sensitivity in detecting 2'FL in HMO, providing a rapid and accurate quantitative analysis of human milk samples at the point-of-care.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2022)

Article Multidisciplinary Sciences

Effects of early-life antibiotics on the developing infant gut microbiome and resistome: a randomized trial

Marta Reyman et al.

Summary: In a randomized trial of 147 infants receiving distinct antibiotic regimens for early-onset neonatal sepsis, Reyman et al. characterize the gut microbiome and resistance profiles, finding differential effects of antibiotic combinations on microbial community composition and antimicrobial resistance genes.

NATURE COMMUNICATIONS (2022)

Review Biochemistry & Molecular Biology

Modeling approaches for probing cross-feeding interactions in the human gut microbiome

Pedro Saa et al.

Summary: Microbial communities exhibit emergent activities different from individual members, influencing host homeostasis or disease. Mathematical and experimental approaches are used to understand and predict interactions within complex communities like the gut microbiota. The review emphasizes recent experimental and modeling approaches for studying interactions within the gut microbiome, focusing on fundamental processes in human health and disease.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2022)

Review Multidisciplinary Sciences

Untangling human milk oligosaccharides and infant gut microbiome

Andrea C. Masi et al.

Summary: The developing gut microbiome in infancy plays a crucial role in shaping the host immune system and metabolic state, and human milk is the main factor influencing its composition. Human milk not only serves to feed the baby but also helps the newborn adapt to its new environment and microbial exposures.

ISCIENCE (2022)

Review Microbiology

The developing infant gut microbiome: A strain-level view

Hagay Enav et al.

Summary: The colonization of the infant microbiome is a complex process influenced by ecological forces and environmental conditions. Recent advancements in strain-level analysis have revealed the immense complexity of the system, providing a better understanding of how strains of the same species spread, colonize, evolve, and impact the host.

CELL HOST & MICROBE (2022)

Review Food Science & Technology

Research progress on conjugated linoleic acid bio-conversion in Bifidobacterium

Yongchao Mei et al.

Summary: This article reviews the current knowledge about Bifidobacterium CLA producers, the complex factors regulating CLA production in Bifidobacterium, the role of CLA production in Bifidobacterium, and the potential mechanism underlying Bifidobacterium CLA production. It offers novel insights into the production of food-grade CLA as well as the rational design of health-promoting fermented foods or synbiotics.

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2022)

Article Cell Biology

Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition

Michael J. Barratt et al.

Summary: Disrupted development of the gut microbiota is a contributing cause of childhood malnutrition. An experiment found that giving B. infantis combined with LNT can increase the abundance of B. infantis subspecies in infants with severe acute malnutrition and promote weight gain, but the effect is still much lower than in healthy controls. A B. infantis strain, Bg_2D9, with superior fitness may have potential in treating malnourished infants.

SCIENCE TRANSLATIONAL MEDICINE (2022)

Article Multidisciplinary Sciences

Human milk oligosaccharide-sharing by a consortium of infant derived Bifidobacterium species

Clodagh Walsh et al.

Summary: Bifidobacteria have the ability to consume human milk oligosaccharides (HMO), leading to positive cooperation and increased bacterial numbers with potentially healthier metabolite balance.

SCIENTIFIC REPORTS (2022)

Article Multidisciplinary Sciences

Characterizing the mucin-degrading capacity of the human gut microbiota

Janiece S. Glover et al.

Summary: This study systematically examined the mucin-degrading profiles of the human gut microbiota and found multiple microbial species in different phyla with mucin-degrading capability. The findings greatly expand our knowledge of microbial-mediated mucin degradation within the human gut microbiota.

SCIENTIFIC REPORTS (2022)

Article Immunology

The Infant Gut Commensal Bacteroides dorei Presents a Generalized Transcriptional Response to Various Human Milk Oligosaccharides

Sivan Kijner et al.

Summary: Human milk oligosaccharides (HMOs) play a crucial role in the infant gut microbiome, benefiting not only Bifidobacterium but also other microbes like Bacteroides. Research reveals variations in HMO utilization across different Bacteroides strains, with B. dorei displaying a comprehensive metabolic response to HMOs, distinct from previously studied Bifidobacterium species.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2022)

Article Ecology

Priority effects shape the structure of infant-type Bifidobacterium communities on human milk oligosaccharides

Miriam N. Ojima et al.

Summary: This study applied assembly theory to investigate the formation of bifidobacterial communities in the infant gut. The results showed that arrival order and sugar consumption phenotypes significantly affected community formation. Bifidobacterium bifidum and Bifidobacterium longum subsp. infantis dominated through inhibitory priority effects, while Bifidobacterium breve benefited from facilitative priority effects and utilized a specific degradant to dominate. This study highlights the importance of initial community assembly and its impact on the maturation trajectory of the infant gut microbiota.

ISME JOURNAL (2022)

Review Nutrition & Dietetics

Intermediate role of gut microbiota in vitamin B nutrition and its influences on human health

Zhijie Wan et al.

Summary: Vitamin B is a group of water-soluble micronutrients derived from the diet, and its interaction with gut microbiota plays a crucial role in the absorption of vitamin B and the function of gut microbiota.

FRONTIERS IN NUTRITION (2022)

Article Nutrition & Dietetics

Infant Formula With a Specific Blend of Five Human Milk Oligosaccharides Drives the Gut Microbiota Development and Improves Gut Maturation Markers: A Randomized Controlled Trial

Miroslava Bosheva et al.

Summary: This study investigated the effects of an infant formula containing five HMOs on gut maturation. The results showed that this formula can support the development of the intestinal immune system and gut barrier function, and shift the gut microbiome closer to that of breastfed infants.

FRONTIERS IN NUTRITION (2022)

Article Nutrition & Dietetics

Host-microbial co-metabolites modulated by human milk oligosaccharides relate to reduced risk of respiratory tract infections

Francois-Pierre Martin et al.

Summary: Human milk oligosaccharides (HMOs) in breast milk, specifically 2-HMO (2'fucosyllactose, lacto-N-neotetraose), have been found to reduce the risk of lower respiratory tract infections (LRTIs) in infants. This study aimed to further investigate the molecular pathways linking 2-HMO formula feeding and LRTI mitigation. The researchers found that 2-HMO formula feeding increased gamma-glutamylation and N-acetylation of amino acids, while decreasing inflammatory signaling lipids. Additionally, specific Bifidobacterium and Bacteroides species were implicated in these metabolic changes. These findings contribute to our understanding of infant gut and microbiome metabolism and how it may impact immune competence.

FRONTIERS IN NUTRITION (2022)

Review Agriculture, Dairy & Animal Science

The interaction among gut microbes, the intestinal barrier and short chain fatty acids

Jiayu Ma et al.

Summary: The interaction between gut microbiota and the host gut is crucial for maintaining the homeostasis of the organism, with short chain fatty acids playing a vital role in regulating intestinal community homeostasis and influencing the host gut barriers.

ANIMAL NUTRITION (2022)

Article Allergy

Human milk oligosaccharide profiles and allergic disease up to 18 years

Caroline J. Lodge et al.

Summary: In this high-allergy-risk birth cohort, certain profiles of human milk oligosaccharides (HMOs) were found to be associated with increased risks of allergic diseases in childhood, while others were associated with decreased risks. Further studies are needed to confirm these findings and explore their potential for intervention.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

Review Nutrition & Dietetics

Probiotics, Prebiotics, and Synbiotics for the Prevention of Necrotizing Enterocolitis

Kiera Murphy et al.

Summary: This article discusses the importance of NEC in preterm infants and the impact of gut microbiota on NEC development, as well as the treatment methods involving modulation of microbiota using probiotics, prebiotics, or their combination. It also analyzes the evidence supporting these methods in reducing the risk of NEC and discusses current clinical practice guidelines recommendations.

FRONTIERS IN NUTRITION (2021)

Review Biochemistry & Molecular Biology

Significance of fucose in intestinal health and disease

Jolene M. Garber et al.

Summary: L-fucose plays a crucial role in biological processes and maintaining a healthy microbiota. Fucosylated oligosaccharides help establish microbiota balance but can also be exploited by pathogens. Deficiencies in fucosylation are associated with specific disease outcomes.

MOLECULAR MICROBIOLOGY (2021)

Article Microbiology

Cross-feeding between Bifidobacterium infantis and Anaerostipes caccae on lactose and human milk oligosaccharides

L. W. Chia et al.

Summary: The establishment of gut microbiota in infants, particularly through human milk oligosaccharides and the trophic interactions between Bifidobacterium infantis and Anaerostipes caccae, plays a crucial role in shaping the gut microbiota and promoting gut maturation.

BENEFICIAL MICROBES (2021)

Review Nutrition & Dietetics

Priming for Life: Early Life Nutrition and the Microbiota-Gut-Brain Axis

Anna Ratsika et al.

Summary: Microbes colonize the human body at birth and coexist with the host, playing a role in programming important bodily systems during critical developmental windows. Early life nutrition is a key factor in perinatal programming and modulation of offspring microbiota.

NUTRIENTS (2021)

Article Medicine, Research & Experimental

Developmental Patterns of Fecal Bile Acids in Healthy Neonates and Children

Jing-Jing Xiong et al.

Summary: Primary bile acids stabilize after 7 days of birth in newborns and tend to remain stable after the neonatal stage. Secondary bile acids gradually increase with the maturation of intestinal flora, reaching a relatively stable level at around 3 years old.

MEDICAL SCIENCE MONITOR (2021)

Article Microbiology

Developmental trajectory of the healthy human gut microbiota during the first 5 years of life

Josefine Roswall et al.

Summary: The gut microbiota is established by four different colonization patterns, with some late colonizers correlating with increased diversity. Children show individual dynamics in the development trajectory of the gut microbiota.

CELL HOST & MICROBE (2021)

Article Microbiology

Bifidobacterium species associated with breastfeeding produce aromatic lactic acids in the infant gut

Martin F. Laursen et al.

Summary: Breastfeeding-associated Bifidobacterium species can convert aromatic amino acids into aromatic lactic acids via an unrecognized enzyme, potentially impacting infant immune function. Longitudinal study of Danish infants showed that faecal concentrations of aromatic lactic acids are positively correlated with specific Bifidobacterium species abundance containing the enzyme. These microbial metabolites may have implications for early life immune function.

NATURE MICROBIOLOGY (2021)

Article Ecology

Key bacterial taxa and metabolic pathways affecting gut short-chain fatty acid profiles in early life

Naoki Tsukuda et al.

Summary: This study explored the early life relationships between SCFA and gut microbiota by analyzing faecal samples collected from 12 subjects over the first two years of life. The research identified three distinct phases of SCFA profiles and their associations with specific gut microbiota. The results showed that butyrate production was linked to Clostridiales species and breastfeeding cessation, while formate production was associated with infant-type bifidobacterial species and HMO-derived fucose.

ISME JOURNAL (2021)

Article Medicine, General & Internal

A Microbiota-Directed Food Intervention for Undernourished Children

Robert Y. Chen et al.

Summary: The study found that providing a microbiota-directed complementary food prototype (MDCF-2) to children with moderate acute malnutrition in Bangladeshi slums showed positive effects on growth, particularly in weight-for-length and weight-for-age z scores, with changes in plasma proteins related to bone growth and neurodevelopment. These findings suggest that targeted manipulation of microbiota components may be linked to growth outcomes in children with moderate acute malnutrition.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Review Endocrinology & Metabolism

Gut Microbiota Development: Influence of Diet from Infancy to Toddlerhood

Martin Frederik Laursen

Summary: Early life is a critical period for the establishment and diversity of gut microbiota, which can be significantly influenced by diet and breastfeeding. Understanding the interactions between diet, gut microbiota, and health is essential for promoting optimal growth and development in early life.

ANNALS OF NUTRITION AND METABOLISM (2021)

Article Biochemistry & Molecular Biology

Bifidobacteria-mediated immune system imprinting early in life

Bethany M. Henrick et al.

Summary: Early immune-microbe interactions play a role in the development of allergies, asthma, and inflammatory diseases. Breastfeeding promotes healthier immune-microbe relationships by providing necessary nutrients to beneficial microbes. The lack of bifidobacteria and genes required for HMO utilization can lead to systemic inflammation and immune dysregulation in early life.
Review Microbiology

The microbiome-shaping roles of bacteriocins

Simon Heilbronner et al.

Summary: Bacteriocins, small antibacterial molecules produced by commensal bacteria, can shape the microbiome composition by providing competitive advantage to producer strains over sensitive strains. They have narrow activity ranges, making them potential agents for precision therapy and infection prevention.

NATURE REVIEWS MICROBIOLOGY (2021)

Review Nutrition & Dietetics

The Mean of Milk: A Review of Human Milk Oligosaccharide Concentrations throughout Lactation

Buket Soyyilmaz et al.

Summary: Human milk oligosaccharides (HMOs) are complex carbohydrates abundant in human milk, with over 200 different structures identified. The concentrations of HMOs in breast milk vary according to lactation period and mother's genetic status. Studies have shown significant variations in HMO concentrations for different types across lactation stages. In mature pooled human milk, the top 15 individual HMOs make up the majority of total HMO concentration.

NUTRIENTS (2021)

Review Cell Biology

Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease

Pooja S. Salvi et al.

Summary: Butyrate acts as a link between the intestinal microbiome and epithelium, affecting colon, tumors, stem cells, and inflammatory diseases differently. It also regulates cellular inflammation, antigen tolerance, and the pathogenesis of intestinal diseases.

CELLS (2021)

Article Biochemistry & Molecular Biology

Longitudinal Profiles of Dietary and Microbial Metabolites in Formula- and Breastfed Infants

Nina Sillner et al.

Summary: The early-life metabolome of the intestinal tract is strongly influenced by colonization of gut microbiota, which is in turn affected by nutrition, such as breast milk or formula. The fecal metabolites of breastfed and formula-fed infants show distinct differences, with breastfed infants having higher levels of unsaturated fatty acids and human milk oligosaccharides. The metabolite profiles of infants converge at the end of the first year coinciding with the introduction of solid foods.

FRONTIERS IN MOLECULAR BIOSCIENCES (2021)

Review Microbiology

Settlers of our inner surface - factors shaping the gut microbiota from birth to toddlerhood

Martin Frederik Laursen et al.

Summary: During the first 3 years of life, the microbial ecosystem within the human gut undergoes unique developmental processes, considered a critical window for gut microbiota development. While advanced bioinformatics and clinical correlation studies are extensive, basic microbial growth physiology has received less attention. Factors influencing infant gut microbiota development include microbial sources, physico-chemical conditions, and nutrient availability.

FEMS MICROBIOLOGY REVIEWS (2021)

Review Gastroenterology & Hepatology

Gut Bacteroides species in health and disease

Hassan Zafar et al.

Summary: The functional diversity of the mammalian intestinal microbiome far exceeds that of the host organism, and microbial genes contribute substantially to the well-being of the host; beneficial gut organisms can also be pathogenic when present in the gut or other locations in the body; Bacteroides metabolize polysaccharides and oligosaccharides, providing nutrition and vitamins to the host and other intestinal microbial residents.

GUT MICROBES (2021)

Review Psychology, Developmental

Annual Research Review: Critical windows - the microbiota-gut-brain axis in neurocognitive development

Caitlin S. M. Cowan et al.

JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY (2020)

Article Food Science & Technology

Breastmilk Lipids and Oligosaccharides Influence Branched Short-Chain Fatty Acid Concentrations in Infants with Excessive Weight Gain

Ceyda Tugba Pekmez et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2020)

Article Multidisciplinary Sciences

Neuronal programming by microbiota regulates intestinal physiology

Yuuki Obata et al.

NATURE (2020)

Article Nutrition & Dietetics

Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula

Lauren R. Brink et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2020)

Article Biotechnology & Applied Microbiology

Ecological Importance of Cross-Feeding of the Intermediate Metabolite 1,2-Propanediol between Bacterial Gut Symbionts

Christopher C. Cheng et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2020)

Article Biochemistry & Molecular Biology

A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors

Ina Nemet et al.

Article Food Science & Technology

Functional Roles of B-Vitamins in the Gut and Gut Microbiome

Takashi Uebanso et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2020)

Article Multidisciplinary Sciences

Bile acids drive the newborn's gut microbiota maturation

N. van Best et al.

NATURE COMMUNICATIONS (2020)

Review Nutrition & Dietetics

Postbiotics-A Step Beyond Pre- and Probiotics

Jakub Zolkiewicz et al.

NUTRIENTS (2020)

Article Gastroenterology & Hepatology

The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics

Kelly S. Swanson et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)

Article Multidisciplinary Sciences

Akkermansia muciniphila uses human milk oligosaccharides to thrive in the early life conditions in vitro

Ioannis Kostopoulos et al.

SCIENTIFIC REPORTS (2020)

Review Pediatrics

The infant gut microbiome as a microbial organ influencing host well-being

Francesca Turroni et al.

ITALIAN JOURNAL OF PEDIATRICS (2020)

Review Gastroenterology & Hepatology

You are what you eat: diet, health and the gut microbiota

Niv Zmora et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)

Review Biochemistry & Molecular Biology

The Human Microbiome and Child Growth - First 1000 Days and Beyond

Ruairi C. Robertson et al.

TRENDS IN MICROBIOLOGY (2019)

Review Food Science & Technology

Advances in Infant Formula Science

Grace J. Ahern et al.

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 10 (2019)

Review Gastroenterology & Hepatology

The role of short-chain fatty acids in microbiota-gut-brain communication

Boushra Dalile et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)

Review Virology

The dawn of phage therapy

Sana Rehman et al.

REVIEWS IN MEDICAL VIROLOGY (2019)

Article Gastroenterology & Hepatology

Role of the microbiome in human development

Maria Gloria Dominguez-Bello et al.

Article Immunology

Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification

Matthew T. Sorbara et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2019)

Article Gastroenterology & Hepatology

Association of Maternal Secretor Status and Human Milk Oligosaccharides With Milk Microbiota: An Observational Pilot Study

Raul Cabrera-Rubio et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2019)

Article Multidisciplinary Sciences

Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway

Rajbir Singh et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Depletion of microbiome-derived molecules in the host using Clostridium genetics

Chun-Jun Guo et al.

SCIENCE (2019)

Review Pediatrics

Functional Gastrointestinal Disorders in Infancy: Impact on the Health of the Infant and Family

Yvan Vandenplas et al.

PEDIATRIC GASTROENTEROLOGY HEPATOLOGY & NUTRITION (2019)

Review Nutrition & Dietetics

Diet-derived microbial metabolites in health and disease

H. M. Roager et al.

NUTRITION BULLETIN (2019)

Review Nutrition & Dietetics

Metabolism of Dietary and Microbial Vitamin B Family in the Regulation of Host Immunity

Ken Yoshii et al.

FRONTIERS IN NUTRITION (2019)

Article Biotechnology & Applied Microbiology

Human milk oligosaccharides and infant gut bifidobacteria: Molecular strategies for their utilization

Pamela Thomson et al.

FOOD MICROBIOLOGY (2018)

Article Allergy

Intestinal microbiota in infants at high risk for allergy: Effects of prebiotics and role in eczema development

Harm Wopereis et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)

Review Multidisciplinary Sciences

Microbial tryptophan catabolites in health and disease

Henrik M. Roager et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1

Ara Koh et al.

Article Multidisciplinary Sciences

Temporal development of the gut microbiome in early childhood from the TEDDY study

Christopher J. Stewart et al.

NATURE (2018)

Article Biochemistry & Molecular Biology

Infant diet and maternal gestational weight gain predict early metabolic maturation of gut microbiomes

Aimee M. Baumann-Dudenhoeffer et al.

NATURE MEDICINE (2018)

Letter Allergy

Human milk oligosaccharides and development of cow's milk allergy in infants

Antti E. Seppo et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2017)

Article Gastroenterology & Hepatology

Influence of Gestational Age, Secretor, and Lewis Blood Group Status on the Oligosaccharide Content of Human Milk

Clemens Kunz et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2017)

Article Nutrition & Dietetics

Emerging issues in complementary feeding: Global aspects

Kim F. Michaelsen et al.

MATERNAL AND CHILD NUTRITION (2017)

Article Microbiology

First Foods and Gut Microbes

Martin F. Laursen et al.

FRONTIERS IN MICROBIOLOGY (2017)

Review Biochemistry & Molecular Biology

A review of the relationship between the gut microbiota and amino acid metabolism

Rui Lin et al.

AMINO ACIDS (2017)

Review Cell Biology

GPCR-Mediated Signaling of Metabolites

Anna Sofie Husted et al.

CELL METABOLISM (2017)

Article Nutrition & Dietetics

Breast milk composition and infant nutrient intakes during the first 12 months of life

V. Grote et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2016)

Article Medicine, General & Internal

Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect

Cesar G. Victora et al.

LANCET (2016)

Article Biochemical Research Methods

Identification of Oligosaccharides in Feces of Breast-fed Infants and Their Correlation with the Gut Microbial Community

Jasmine C. C. Davis et al.

MOLECULAR & CELLULAR PROTEOMICS (2016)

Article Multidisciplinary Sciences

Human gut microbes impact host serum metabolome and insulin sensitivity

Helle Krogh Pedersen et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation

Kei E. Fujimura et al.

NATURE MEDICINE (2016)

Review Biochemistry & Molecular Biology

The microbiome in early life: implications for health outcomes

Sabrina Tamburini et al.

NATURE MEDICINE (2016)

Review Biochemistry & Molecular Biology

Signals from the gut microbiota to distant organs in physiology and disease

Bjoern Schroeder et al.

NATURE MEDICINE (2016)

Review Food Science & Technology

Conjugated Linoleic Acid: Potential Health Benefits as a Functional Food Ingredient

Jun Ho Kim et al.

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 7 (2016)

Review Microbiology

The Neuro-endocrinological Role of Microbial Glutamate and GABA Signaling

Roberto Mazzoli et al.

FRONTIERS IN MICROBIOLOGY (2016)

Article Pediatrics

Infant Early Gut Colonization by Lachnospiraceae: High Frequency of Ruminococcus gnavus

Valeria Sagheddu et al.

FRONTIERS IN PEDIATRICS (2016)

Article Microbiology

Having older siblings is associated with gut microbiota development during early childhood

Martin Frederik Laursen et al.

BMC MICROBIOLOGY (2015)

Article Biochemistry & Molecular Biology

Personalized Nutrition by Prediction of Glycemic Responses

David Zeevi et al.

Article Microbiology

Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life

Fredrik Backhed et al.

CELL HOST & MICROBE (2015)

Article Obstetrics & Gynecology

The functional biology of human milk oligosaccharides

Lars Bode

EARLY HUMAN DEVELOPMENT (2015)

Article Multidisciplinary Sciences

Secretor Status Is Strongly Associated with Microbial Alterations Observed during Pregnancy

Himanshu Kumar et al.

PLOS ONE (2015)

Article Biochemistry & Molecular Biology

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

Filipe De Vadder et al.

Review Cell Biology

Vitamin B12 as a Modulator of Gut Microbial Ecology

Patrick H. Degnan et al.

CELL METABOLISM (2014)

Article Multidisciplinary Sciences

Persistent gut microbiota immaturity in malnourished Bangladeshi children

Sathish Subramanian et al.

NATURE (2014)

Article Gastroenterology & Hepatology

Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids

Gijs den Besten et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2013)

Review Biotechnology & Applied Microbiology

Bacteriocin production by Bifidobacterium spp. A review

Fabio Andres Castillo Martinez et al.

BIOTECHNOLOGY ADVANCES (2013)

Article Microbiology

Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit

Anita Wichmann et al.

CELL HOST & MICROBE (2013)

Article Multidisciplinary Sciences

Utilisation of Mucin Glycans by the Human Gut Symbiont Ruminococcus gnavus Is Strain-Dependent

Emmanuelle H. Crost et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition

Shigenobu Kishino et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor

Michelle I. Smith et al.

SCIENCE (2013)

Article Biotechnology & Applied Microbiology

Is the production of the biogenic amines tyramine and putrescine a species-level trait in enterococci?

Victor Ladero et al.

FOOD MICROBIOLOGY (2012)

Review Biochemistry & Molecular Biology

Human milk oligosaccharides: Every baby needs a sugar mama

Lars Bode

GLYCOBIOLOGY (2012)

Article Multidisciplinary Sciences

Human gut microbiome viewed across age and geography

Tanya Yatsunenko et al.

NATURE (2012)

Article Multidisciplinary Sciences

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

Zeneng Wang et al.

NATURE (2011)

Article Transplantation

p-Cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease

I-Wen Wu et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2011)

Article Gastroenterology & Hepatology

Short-Chain Fatty Acids Regulate the Enteric Neurons and Control Gastrointestinal Motility in Rats

Rodolphe Soret et al.

GASTROENTEROLOGY (2010)

Article Multidisciplinary Sciences

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

Maria G. Dominguez-Bello et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Biochemistry & Molecular Biology

Nursing our microbiota: molecular linkages between bifidobacteria and milk oligosaccharides

David A. Sela et al.

TRENDS IN MICROBIOLOGY (2010)

Review Biochemistry & Molecular Biology

Bile acids as regulatory molecules

Phillip B. Hylemon et al.

JOURNAL OF LIPID RESEARCH (2009)

Article Multidisciplinary Sciences

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

William R. Wikoff et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Review Biotechnology & Applied Microbiology

Targeting bile-acid signalling for metabolic diseases

Charles Thomas et al.

NATURE REVIEWS DRUG DISCOVERY (2008)

Review Biochemistry & Molecular Biology

Bile salt biotransformations by human intestinal bacteria

JM Ridlon et al.

JOURNAL OF LIPID RESEARCH (2006)

Article Biotechnology & Applied Microbiology

Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product

SH Duncan et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2004)

Article Nutrition & Dietetics

Free amino acid content in standard infant formulas:: Comparison with human milk

C Agostoni et al.

JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION (2000)