Journal
LETTERS IN DRUG DESIGN & DISCOVERY
Volume 14, Issue 2, Pages 201-208Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1570180813666160609082633
Keywords
1; 2; 4-triazole; benzimidazole; antioxidant activity; CUPRAC; ABTS; DPPH
Categories
Funding
- Recep Tayyip Erdogan University Scientific Research Project Unit [2014.102.02.05]
- Recep Tayyip Erdogan University
Ask authors/readers for more resources
Various benzimidazole compounds containing a triazole nucleus were synthesized and screened for their antioxidant activies. The structures of newly synthesized compounds were characterized by H-1 NMR, C-13 NMR and elemental analysis data. Antioxidant features of the synthesized compounds were investigated by different processes such as 2,2-diphenyl picryl hydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) and CUPric reducing antioxidant capacity (CUPRAC) methods. Significant antioxidant activity was achieved by some of the synthesized compounds demonstrated as much activity as standards (AA and BHT). Correlation analysis between the CUPRAC antioxidant and ABTS radical scavenging assays revealed positive correlation (R-2=0.926), indicating differing antioxidant activities based on the reaction mechanism.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available