Journal
PHARMACEUTICS
Volume 15, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/pharmaceutics15061615
Keywords
beta-glucans; immune system; dendritic cells; adjuvants
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Beta-glucan, a homopolysaccharide composed of D-glucose, is widely found in cereals and microorganisms and possesses various biological activities including anti-inflammatory, antioxidant, and anti-tumor properties. Recent research has shown that beta-glucan acts as a physiologically active biological response modulator, promoting dendritic cell maturation, cytokine secretion, and regulating adaptive immune responses, all of which are directly connected to beta-glucan-regulated glucan receptors.
beta-glucan, one of the homopolysaccharides composed of D-glucose, exists widely in cereals and microorganisms and possesses various biological activities, including anti-inflammatory, antioxidant, and anti-tumor properties. More recently, there has been mounting proof that beta-glucan functions as a physiologically active biological response modulator (BRM), promoting dendritic cell maturation, cytokine secretion, and regulating adaptive immune responses-all of which are directly connected with beta-glucan-regulated glucan receptors. This review focuses on the sources, structures, immune regulation, and receptor recognition mechanisms of beta-glucan.
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