Prevalence, Risk, and Challenges of Extemporaneous Preparation for Pediatric Patients in Developing Nations: A Review

Extemporaneous preparations are still widely prescribed for pediatric patients with special treatments of certain doses and/or combinations of drugs. Several problems related to extemporaneous preparations have been linked to the incidence of adverse events or a lack of therapeutic effectiveness. Developing nations are facing the challenges of compounding practices. The prevalence of compounded medication in developing nations must be explored to determine the urgency of compounding practices. Furthermore, the risks and challenges are described and explained through investigation and collection of numerous scientific articles from reputable databases, including Web of Science, Scopus, and PubMed. Pediatric patients need compounded medication related to the appropriate dosage form and dosage adjustment. Notably, it is important to observe extemporaneous preparations in order to provide patient-oriented medication.

Automated summary

Extemporaneous preparations are widely used for pediatric patients with special treatments, but they come with several problems that can lead to adverse events or a lack of therapeutic effectiveness. Developing nations are facing challenges in compounding practices, and the prevalence of compounded medication in these nations needs to be explored to determine the urgency of addressing these challenges. Through investigation and collection of scientific articles from reputable databases, the risks and challenges associated with extemporaneous preparations are described and explained.