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Polymeric Micellar Systems-A Special Emphasis on Smart Drug Delivery

Journal

PHARMACEUTICS
Volume 15, Issue 3, Pages -

Publisher

MDPI
DOI: 10.3390/pharmaceutics15030976

Keywords

polymeric micelles; anti-cancer drugs; drug delivery; stimuli-responsive micelles

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Concurrent developments in anticancer nanotechnological treatments have been observed as the burden of cancer increases every year. The advancement in the field of material science and nanomedicine has led to improved drug delivery systems with proven efficacy and fewer side effects. Various intelligent nanomedicines are being created using lipids, polymers, and inorganic and peptide-based nanomedicines. Thorough knowledge of these nanomedicines is crucial for developing very promising drug delivery systems. Polymeric micelles are simple to make and have high solubilization characteristics, making them a promising alternative in nanosystems for cancer treatment.
Concurrent developments in anticancer nanotechnological treatments have been observed as the burden of cancer increases every year. The 21st century has seen a transformation in the study of medicine thanks to the advancement in the field of material science and nanomedicine. Improved drug delivery systems with proven efficacy and fewer side effects have been made possible. Nanoformulations with varied functions are being created using lipids, polymers, and inorganic and peptide-based nanomedicines. Therefore, thorough knowledge of these intelligent nanomedicines is crucial for developing very promising drug delivery systems. Polymeric micelles are often simple to make and have high solubilization characteristics; as a result, they seem to be a promising alternative to other nanosystems. Even though recent studies have provided an overview of polymeric micelles, here we included a discussion on the intelligent drug delivery from these systems. We also summarized the state-of-the-art and the most recent developments of polymeric micellar systems with respect to cancer treatments. Additionally, we gave significant attention to the clinical translation potential of polymeric micellar systems in the treatment of various cancers.

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