☆ 4.7 Review

Prospects for the Use of Metal-Based Nanoparticles as Adjuvants for Local Cancer Immunotherapy

PHARMACEUTICS (2023)

Related references

Note: Only part of the references are listed.
Review Chemistry, Multidisciplinary

Immune-based combination therapy to convert immunologically cold tumors into hot tumors: an update and new insights

Jiao-jiao Ni et al.

Summary: As a breakthrough strategy for cancer treatment, immunotherapy stimulates the immune system to fight cancer, providing a durable antitumor response. Due to the low response rate and unique toxicity profiles of immunotherapy, combining it with other therapies has gained attention. Immune-based combination therapy has achieved promising results in clinical trials, with FDA approval for certain cancers.

ACTA PHARMACOLOGICA SINICA (2023)

Add to Collection
Article

DNA Damage and Apoptosis as In-Vitro Effect Biomarkers of Titanium Dioxide Nanoparticles (TiO2-NPs) and the Food Additive E171 Toxicity in Colon Cancer Cells: HCT-116 and Caco-2

Margherita Ferrante et al.

International Journal of Environmental Research and Public Health (2023)

Add to Collection
Review Biotechnology & Applied Microbiology

Metal ions and nanometallic materials in antitumor immunity: Function, application, and perspective

Feiyang Shen et al.

Summary: Even slight changes in the concentrations of metal ions can have amplified effects on signaling cascades that regulate tumor microenvironment and immune status, ultimately influencing the network of antitumor immunity. Metal ions are widely used in antitumor therapy as immune modulators due to their influence on cancer cell fate and participation in innate and adaptive immunity. Nanomedicine, with its precise delivery and responsive release capabilities, provides an ideal platform for the application of metal ions in cancer treatment, overcoming the disadvantages of low target selectivity and systemic toxicity.

JOURNAL OF NANOBIOTECHNOLOGY (2023)

Add to Collection
Editorial Material Oncology

Immune Checkpoint Inhibitors in Cancer Therapy-How Can We Improve Clinical Benefits?

Constantin N. N. Baxevanis

CANCERS (2023)

Add to Collection
Review Nanoscience & Nanotechnology

Overview of mechanism and consequences of endothelial leakiness caused by metal and polymeric nanoparticles

Magdalena Lasak et al.

Summary: Nanoparticles with unique physicochemical properties can overcome biological barriers and are considered one of the best materials with anticancer properties. The interaction of nanoparticles with the endothelium can lead to nanoparticle-modulated endothelial leakiness (NanoEL), which can be beneficial for drug delivery but also carries risks. Understanding the mechanism and degree of induction of NanoEL, as well as the potential risks, is crucial for the development of effective therapeutic strategies.

BEILSTEIN JOURNAL OF NANOTECHNOLOGY (2023)

Add to Collection
Review Engineering, Biomedical

Nanoparticle-Mediated STING Activation for Cancer Immunotherapy

Yongjuan Li et al.

Summary: As the first line of host defense against pathogenic infections, innate immunity plays a key role in anti-tumor immunotherapy. The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) (cGAS-STING) pathway and its activation of proinflammatory cytokines and chemokines have attracted attention for cancer immunotherapy. However, the limitations of small molecule STING agonists, such as fast excretion, low bioavailability, nonspecificity, and adverse effects, hinder their therapeutic efficacy. Nanodelivery systems with appropriate characteristics can address these challenges.

ADVANCED HEALTHCARE MATERIALS (2023)

Add to Collection
Article Nanoscience & Nanotechnology

Importance of Metal Biotransformation in Cell Response to Metallic Nanoparticles: A Transcriptomic Meta-analysis Study

Alice Balfourier et al.

Summary: Metallic nanoparticles and ions have different impacts on human cell responses, with their chemical properties being more important than known biological functions. The response to nanoparticles is mainly influenced by the ions they contain and depends on their solubility. Nanoparticles affect cell response by altering genes related to intracellular transport and the cytoskeleton. Moreover, several metals trigger a cell response governed by metallothioneins, along with specific signatures for each element.

ACS NANOSCIENCE AU (2023)

Add to Collection
Article Chemistry, Multidisciplinary

Aluminum nanoparticles deliver a dual-epitope peptide for enhanced anti-tumor immunotherapy

Shuting Bai et al.

Summary: This study proposed an innovative peptide vaccine strategy to simultaneously activate CD8(+) and CD4(+) T cell responses by combining MHC-I and MHC-II epitopes into one long peptide antigen. The developed nanovaccine significantly inhibited tumor growth and prolonged mouse survival.

JOURNAL OF CONTROLLED RELEASE (2022)

Add to Collection
Letter Oncology

HLF regulates ferroptosis, development and chemoresistance of triple-negative breast cancer by activating tumor cell-macrophage crosstalk

Hengyu Li et al.

Summary: Tumor-associated macrophages (TAMs) promote the activation of hepatic leukemia factor (HLF) in triple-negative breast cancer (TNBC) cells through the secretion of transforming growth factor-beta1 (TGF-beta 1) and subsequently, HLF transactivates gamma-glutamyltransferase 1 (GGT1) to enhance ferroptosis resistance. This process drives TNBC cell proliferation, metastasis, and cisplatin resistance. Additionally, TNBC cells activate the JAK2/STAT3 axis to induce TGF-beta 1 secretion by TAMs, forming a feed-forward circuit. The combination of HLF and GGT1 values can improve the accuracy of TNBC patient prognosis.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2022)

Add to Collection
Review Oncology

Immune-checkpoint inhibitors: long-term implications of toxicity

Douglas B. Johnson et al.

Summary: Immune-checkpoint inhibitors have improved outcomes for advanced-stage solid tumour patients, but they also carry the risk of chronic toxicities that can affect patients' quality of life. While evidence on chronic toxicities is limited, emerging evidence suggests that they may be more common than previously thought. These toxicities can affect various organ systems and may even lead to fatal outcomes. Research on the effects of immune-checkpoint blockade on other immune processes is also important for cancer survivors.

NATURE REVIEWS CLINICAL ONCOLOGY (2022)

Add to Collection
Article Engineering, Biomedical

Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity

Yash Agarwal et al.

Summary: Intratumoural injection of recombinantly expressed cytokines bound to aluminium hydroxide leads to long-term retention of the cytokines in tumours with minimal side effects. This approach enhances the activity of tumour necrosis factors, promotes T-cell activation, increases the production of tumour-specific T-cells, and improves response to immunotherapy.

NATURE BIOMEDICAL ENGINEERING (2022)

Add to Collection
Review Oncology

Multifunctional inorganic nanomaterials for cancer photoimmunotherapy

Lu Tang et al.

Summary: Combining immunotherapy and phototherapy is considered the ideal approach for treating tumors. Inorganic nanomaterials, with their unique physicochemical properties, play a crucial role in photoimmunotherapy (PIT) by serving as carriers for immunomodulatory agents and as photothermal agents or photosensitizers in phototherapy.

CANCER COMMUNICATIONS (2022)

Add to Collection
Review Biochemistry & Molecular Biology

Aluminium Nanoparticles as Efficient Adjuvants Compared to Their Microparticle Counterparts: Current Progress and Perspectives

Ali Nazarizadeh et al.

Summary: Aluminium compounds are commonly used as adjuvants in vaccines due to their improved tolerability. Recent studies have shown that moving from microparticles to nanoparticles can modify the immune responses induced by aluminium-based adjuvants. This review compares the adjuvant properties of aluminium nanoparticles and microparticles in the context of infectious disease vaccines and cancer immunotherapy.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Add to Collection
Review Oncology

Cancer vaccines as promising immuno-therapeutics: platforms and current progress

Jian Liu et al.

Summary: Research on tumor immunotherapy has made significant progress, and cancer vaccines have emerged as a promising therapeutic strategy. Cancer vaccines stimulate anti-tumor immunity with tumor antigens, potentially overcoming immune suppression and inducing both humoral and cellular immunity. This review introduces the working mechanism of cancer vaccines, summarizes different development platforms, and highlights their clinical research progress, with a focus on clinical application and therapeutic efficacy.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2022)

Add to Collection
Article Chemistry, Applied

Upconversion nanoparticles: Recent strategies and mechanism based applications

Neha Dubey et al.

Summary: Upconversion nanoparticles doped with lanthanides can efficiently convert near-infrared excitation into UV and visible emissions, making them appealing materials for applications like drug delivery and bioimaging.

JOURNAL OF RARE EARTHS (2022)

Add to Collection
Article Chemistry, Multidisciplinary

DNA-Based MXFs to Enhance Radiotherapy and Stimulate Robust Antitumor Immune Responses

Yu Yang et al.

Summary: Metal X Frameworks (MXFs) constructed from metal ions and biomacromolecules via coordination interactions exhibit crystalline structures and diverse functionalities. This study showcases the application of a specific MXF composed of Hf4+ and CpG oligodeoxynucleotides in high-Z elements-enhanced photon radiotherapy and immune responses, leading to efficient tumor suppression. The findings highlight the potential of MXFs in fabricating various functional materials and stimulating systemic immune responses through localized radiotherapy.

NANO LETTERS (2022)

Add to Collection
Review Genetics & Heredity

Gene-Immune Therapy of Cancer: Approaches and Problems

I. Alekseenko et al.

Summary: Tumor heterogeneity and therapy resistance require combinatorial approaches. Immunotherapy has revolutionized cancer treatment. Local therapy and intratumoral introduction of therapeutic genes can reduce side effects and achieve targeted treatment.

RUSSIAN JOURNAL OF GENETICS (2022)

Add to Collection
Article Multidisciplinary Sciences

Copper induces cell death by targeting lipoylated TCA cycle proteins

Peter Tsvetkov et al.

Summary: Copper is an essential cofactor for all organisms, but excessive copper can lead to cell death. We found that copper-dependent cell death mechanism is different from known mechanisms, and it is related to mitochondrial respiration. Copper directly binds to lipoylated components of the tricarboxylic acid cycle, causing protein aggregation and loss of iron-sulfur cluster proteins, ultimately leading to cell death.

SCIENCE (2022)

Add to Collection
Article Chemistry, Multidisciplinary

Combination of Metal-Phenolic Network-Based Immunoactive Nanoparticles and Bipolar Irreversible Electroporation for Effective Cancer Immunotherapy

Jun-Hyeok Han et al.

Summary: In this study, a novel nanoparticle in combination with irreversible electroporation (IRE) was developed for effective cancer immunotherapy. The nanoparticle, synthesized and coated, can be effectively internalized by antigen-presenting cells and trigger an immune response. Notably, the nanoparticle demonstrated longer retention time in the tumor compared to the free drug. Tailored IRE expanded the ablation zone and enhanced therapeutic efficacy. Ultimately, the combined treatment successfully inhibited tumor growth and prolonged survival.

SMALL (2022)

Add to Collection
Review Pharmacology & Pharmacy

Symphony of nanomaterials and immunotherapy based on the cancer-immunity cycle

Qianqian Li et al.

Summary: The immune system plays a critical role in cancer initiation and progression. Recent advancements in nanomaterials have expanded their applications in cancer immunotherapies, including drug carriers, inducers of immunogenic cell death, and immunomodulators. Nanomaterials can act as an integrated platform targeting multiple steps of the cancer-immunity cycle simultaneously, enhancing the effectiveness of anticancer immune response.

ACTA PHARMACEUTICA SINICA B (2022)

Add to Collection
Review Pharmacology & Pharmacy

Advances in the Synthesis and Application of Magnetic Ferrite Nanoparticles for Cancer Therapy

Seipati Rosemary Mokhosi et al.

Summary: This review discusses the application of iron-oxide-based nanoparticles in cancer therapy, with a focus on recent research advances in using ferrites as potential nanocarriers. Surface modifications and functionalization with specific biomolecules are highlighted as methods to improve efficiency. The challenges and solutions for the use of ferrites in cancer therapy are also summarized.

PHARMACEUTICS (2022)

Add to Collection
Review Immunology

An Overview of Vaccine Adjuvants: Current Evidence and Future Perspectives

Alessio Facciola et al.

Summary: Vaccines are crucial in preventing infectious diseases, and adjuvants play a key role in enhancing vaccine efficacy. Recent research has focused on developing new compounds with effective adjuvant properties and improved safety. Modern technologies like nanotechnologies and molecular biology have improved vaccine production by enhancing both antigen and adjuvant components. Microparticles, emulsions, and immune stimulators are being explored for their potential in vaccine production. While vaccine adjuvants may have potential side effects, the significant value of vaccines cannot be denied, particularly in managing future pandemics. Research into adjuvants could play a leading role in producing more effective vaccines.

VACCINES (2022)

Add to Collection
Review Biochemistry & Molecular Biology

The Role of the Metabolism of Zinc and Manganese Ions in Human Cancerogenesis

Julian Markovich Rozenberg et al.

Summary: Metal ion homeostasis is crucial for life, with manganese and zinc playing key roles in cancer progression by potentially cooperatively regulating oncogenesis. Both ions influence apoptosis, transcriptional regulation, and immune response through mitochondria and the cGAS-STING signaling pathway, impacting treatment efficacy in animal models and clinical trials. Novel strategies targeting the regulation of both zinc and manganese in cancer are predicted to complement current therapeutic approaches.

BIOMEDICINES (2022)

Add to Collection
Article Multidisciplinary Sciences

Toxicology assessment of manganese oxide nanomaterials with enhanced electrochemical properties using human in vitro models representing different exposure routes

Natalia Fernandez-Pampin et al.

Summary: This study conducted a comparative human toxicity assessment between newly developed Mn3O4 nanoparticles with enhanced electrochemical properties and their precursor material. The results showed that both nanomaterials induced ROS in cells and had differences in terms of surface area and electrochemical properties. Skin irritation potential was not observed for the studied nanomaterials. The findings highlight the importance of using different human in vitro models to understand the potential impact of nanomaterials on different exposure routes.

SCIENTIFIC REPORTS (2022)

Add to Collection
Review Cell Biology

Toward Establishing an Ideal Adjuvant for Non-Inflammatory Immune Enhancement

Tsukasa Seya et al.

Summary: The vertebrate immune system functions to eliminate foreign nucleic acids and proteins from infectious diseases and tumors. Adjuvants are used to boost immunity, but evaluating their efficacy and safety is challenging.

CELLS (2022)

Add to Collection
Review Oncology

Current and novel therapeutic strategies for optimizing immunotherapy outcomes in advanced non-small cell lung cancer

Claudio Martin et al.

Summary: During the past decade, immunotherapy has greatly improved outcomes for NSCLC patients. However, monotherapy with immune checkpoint inhibitors (ICIs) is not effective for all patients, leading researchers to explore combination approaches to optimize clinical outcomes.

FRONTIERS IN ONCOLOGY (2022)

Add to Collection
Review Cell Biology

Natural killer cell awakening: unleash cancer-immunity cycle against glioblastoma

Minjie Wang et al.

Summary: This article discusses the traditional treatment methods and current immunotherapy strategies for glioblastoma, with a focus on the potential of NK cells as immune regulatory cells in treating glioblastoma.

CELL DEATH & DISEASE (2022)

Add to Collection
Article Biotechnology & Applied Microbiology

Iron oxide@chlorophyll clustered nanoparticles eliminate bladder cancer by photodynamic immunotherapy-initiated ferroptosis and immunostimulation

Yu-Cheng Chin et al.

Summary: Designing a multifunctional nanoparticle that boosts programmed cell death and immunoactivation has potential as a treatment strategy for bladder cancer. In this study, cluster-structured nanoparticles were developed that could perform fluorescence, change the redox balance, and attenuate lipid peroxidation. Targeting the bladder wall and inducing cytotoxicity and ferroptosis resulted in a reprogramming of the tumor microenvironment from immunosuppressive to immunostimulatory. Intravesical instillation of these nanoparticles improved antitumor efficacy and survival rates.

JOURNAL OF NANOBIOTECHNOLOGY (2022)

Add to Collection
Article Immunology

Cuproptosis-Related Risk Score Predicts Prognosis and Characterizes the Tumor Microenvironment in Hepatocellular Carcinoma

Zhen Zhang et al.

Summary: The study finds that FDX1 is downregulated in hepatocellular carcinoma (HCC), and high expression of FDX1 is associated with longer survival time. HCC patients with high cuproptosis-related risk score (CRRS) have significantly lower overall survival (OS) and are enriched in cancer-related pathways. Mutation analyses reveal high mutational frequency of tumor suppressors such as P53 and BAP1, and low mutational frequency of CTNNB1 in high-CRRS HCC patients. Additionally, high CRRS is associated with increased pro-tumor immune infiltrates and high expression of immune checkpoints. Furthermore, CRRS has a high predictive value in determining the efficiency of sorafenib and non-responsiveness to TACE in HCC patients.

FRONTIERS IN IMMUNOLOGY (2022)

Add to Collection
Article Medicine, General & Internal

Applications of rare earth elements in cancer: Evidence mapping and scientometric analysis

Jinyu Wang et al.

Summary: The use of rare earth elements in cancer diagnosis and therapy has gained attention, but there is limited research on their current status and future trends. This study analyzed literature data and found that the United States was the most productive country and the Chinese Academy of Sciences was the most frequent contributor. Close collaboration between countries and institutions was observed.

FRONTIERS IN MEDICINE (2022)

Add to Collection
Review Engineering, Biomedical

Integration of Manganese Dioxide-Based Nanomaterials for Biomedical Applications

Yudong Sun et al.

Summary: This article discusses the importance of MnO2 nanomaterials in biomedical applications and their potential in tumor imaging and cancer treatment. The synthesis methods of different MnO2 nanostructures are first introduced, followed by their applications in biosensing and cancer therapy. The current challenges and future directions in this field are also discussed.

ADVANCED NANOBIOMED RESEARCH (2022)

Add to Collection
Article Nanoscience & Nanotechnology

Collagenase-Loaded H-TiO2 Nanoparticles Enhance Ultrasound Imaging-Guided Sonodynamic Therapy in a Pancreatic Carcinoma Xenograft Model via Digesting Stromal Barriers

Jiali Luo et al.

Summary: In this study, collagenase-loaded hollow TiO2 nanoparticles were synthesized to degrade stromal barriers in pancreatic cancer and generate reactive oxygen species. These nanoparticles effectively reduced intratumoral pressure and enhanced the penetration and retention within tumor tissues. Moreover, they improved intratumoral ultrasound signal and provided a highly effective sonodynamic therapy for pancreatic cancer.

ACS APPLIED MATERIALS & INTERFACES (2022)

Add to Collection
Article Chemistry, Multidisciplinary

An Enzyme-Engineered Nonporous Copper(I) Coordination Polymer Nanoplatform for Cuproptosis-Based Synergistic Cancer Therapy

Yuzhi Xu et al.

Summary: Cuproptosis, a copper-dependent form of regulated cell death, offers great opportunities for cancer treatment. In this study, a glucose oxidase (GOx)-engineered nonporous copper(I) 1,2,4-triazolate ([Cu(tz)]) coordination polymer (CP) nanoplatform, denoted as GOx@[Cu(tz)], is developed for starvation-augmented cuproptosis and photodynamic synergistic therapy. In vivo experimental results show its effectiveness in inhibiting tumor growth.

ADVANCED MATERIALS (2022)

Add to Collection
Article Chemistry, Multidisciplinary

Lanthanide-Nucleotide Coordination Nanoparticles for STING Activation

Zichao Luo et al.

Summary: This study presents the design and synthesis of nanoparticle formulations that can stimulate immune responses and inhibit tumor growth. These nanoparticles, which act as surrogates for STING agonists, show improved bioactivity and immune enhancement compared to traditional agonists.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

Add to Collection
Article Multidisciplinary Sciences

Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies

Emi A. Lutz et al.

Summary: The study found that anchoring IFNs to aluminum-hydroxide particles can improve their retention and efficacy in tumors, significantly enhancing the cure rate of B16F10 tumors. Additionally, alum-anchored IFNs in combination with anti-PD-1 antibody or interleukin-2 produced different T cell phenotypes and resistance to tumor rechallenge.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)

Add to Collection
Review Biochemistry & Molecular Biology

Regulation mechanism of ferroptosis and its research progress in tumor immunotherapy

Jing Xu et al.

Summary: Ferroptosis is a novel form of regulated cell death that depends on iron and is mainly caused by accumulation of lipid peroxides and reactive oxygen species. It plays a crucial role in the treatment of malignant tumors, especially in immunotherapy. This study aims to explore the characteristics of ferroptosis and its potential application in anti-tumor immunotherapy.

FRONTIERS IN MOLECULAR BIOSCIENCES (2022)

Add to Collection
Article Nanoscience & Nanotechnology

Theranostics through Utilizing Cherenkov Radiation of Radioisotope Zr-89 with a Nanocomposite Combination of TiO2 and MnO2

Pyeong Seok Choi et al.

Summary: Cherenkov radiation is being studied for cancer detection and therapy. Nanoparticles are used to develop a theranostic platform for visualizing therapy delivery and generating reactive oxygen species to kill cancer cells.

ACS APPLIED MATERIALS & INTERFACES (2022)

Add to Collection
Review Oncology

Igniting Hope for Tumor Immunotherapy: Promoting the Hot and Cold Tumor Transition

Chen Wei et al.

Summary: The discovery of immune checkpoint inhibitors (ICIs) has revolutionized tumor immunotherapy by harnessing the killing effects of T cells in the tumor microenvironment. However, converting immunosuppressive "cold" tumors to "hot" tumors with adequate T-cell infiltration remains a key challenge. This review systematically outlines the mechanisms underlying the immunosuppressive tumor microenvironment in cold tumors and discusses therapeutic strategies for promoting T-cell infiltration in cold tumors. Additionally, the potential of therapeutic tools such as oncolytic viruses, nanoparticles, and photothermal therapy in restoring immune activity in cold tumors is thoroughly reviewed.

CLINICAL MEDICINE INSIGHTS-ONCOLOGY (2022)

Add to Collection
Review Oncology

Immune escape mechanisms and therapeutic approaches in cancer: the cancer-immunity cycle

Angelika M. Starzer et al.

Summary: The introduction of immune checkpoint inhibitors has revolutionized cancer treatment, but not all patients respond. The cancer-immunity cycle, when properly activated, is crucial for the effectiveness of immune checkpoint inhibitors. However, not all patients and cancer types have an equally functioning cycle. Personalized treatment approaches should take into account the normal and malfunctioning steps of the individual patient's specific cancer-immunity cycle.

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2022)

Add to Collection
Article Oncology

NBTXR3, a first-in-class radioenhancer for pancreatic ductal adenocarcinoma: Report of first patient experience

Alexander F. Bagley et al.

Summary: NBTXR3 has shown clinical activity in PDAC patients who are not eligible for surgery. Local endoscopic delivery of NBTXR3 followed by radiation therapy demonstrated feasibility and tolerance in treating pancreatic cancer, resulting in tumor stability.

CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY (2022)

Add to Collection
Article Chemistry, Multidisciplinary

Biosynthesis of copper oxide nanoparticles and its therapeutic efficacy against colon cancer

Shams Tabrez et al.

Summary: In this study, pumpkin seed extract was used to synthesize copper oxide nanoparticles and their anticancer activity was evaluated in colorectal cancer cells. The results showed that the biogenically synthesized CuO NPs exhibited significant inhibitory effects on cancer cell growth and induced apoptosis. Further studies are recommended to validate these findings using additional models.

NANOTECHNOLOGY REVIEWS (2022)

Add to Collection
Review Hematology

Intratumoral cancer immunotherapy exploiting anti-viral immunity

Norimitsu Kadowaki

Summary: Immunotherapy has become the mainstream of cancer therapies, but it is only effective for a limited proportion of patients. Intratumoral immunotherapy, which triggers innate immunity at the tumor site, is a promising strategy. Many preclinical and clinical trials have shown significant antitumor effects in mice using this approach.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEMATOPATHOLOGY (2022)

Add to Collection
Article Biochemistry & Molecular Biology

Roles of Ion Fluxes, Metabolism, and Redox Balance in Cancer Therapy

Huan-Ling Lai et al.

Summary: Recent studies have shown that targeting key ion channels, metabolic enzymes, and redox proteins in cancer cells can effectively inhibit cancer growth. Additionally, the application of advanced technologies can accelerate the detection of ion, metabolic, and redox changes, improving cancer diagnosis and treatment.

ANTIOXIDANTS & REDOX SIGNALING (2021)

Add to Collection
Review Nanoscience & Nanotechnology

Nanomaterials for T-cell cancer immunotherapy

Ningqiang Gong et al.

Summary: T-cell-based immunotherapies show promise in treating cancer, but face challenges such as insufficient expansion of transferred T cells and inefficient trafficking into tumors. Nanomaterials offer a solution to enhance T-cell therapy by overcoming physical barriers and modulating tumor microenvironments.

NATURE NANOTECHNOLOGY (2021)

Add to Collection
Review Biochemistry & Molecular Biology

The Abscopal Effect: A Review of Pre-Clinical and Clinical Advances

James R. Janopaul-Naylor et al.

Summary: Combining radiotherapy with immunotherapy can enhance the abscopal response, showing a synergistic effect on both local and distant tumors.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection
Review Biotechnology & Applied Microbiology

Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages

Camila Sales Nascimento et al.

Summary: Cancer immunotherapy focuses on activating the patient's immune system against cancer, while interest in metabolic reprogramming of tumor-associated macrophages has increased as a therapeutic strategy. Iron metabolism is a key in reprogramming macrophages to a tumor suppressor phenotype, with iron oxide nanoparticles emerging as a potential anti-tumor strategy.

NANOMEDICINE (2021)

Add to Collection
Article Nanoscience & Nanotechnology

Amplifying STING activation by cyclic dinucleotide-manganese particles for local and systemic cancer metalloimmunotherapy

Xiaoqi Sun et al.

Summary: Metalloimmunotherapy utilizes metal ions to amplify the anti-tumour immune response promoted by STING agonists, forming nanoparticles that effectively deliver STING agonists and achieve remarkable therapeutic efficacy in multiple tumour models. This work highlights the great potential of coordination nanomedicine for metalloimmunotherapy.

NATURE NANOTECHNOLOGY (2021)

Add to Collection
Review Immunology

Cancer Vaccines: Adjuvant Potency, Importance of Age, Lifestyle, and Treatments

Stefania Cuzzubbo et al.

Summary: The discovery of tumor antigens has led to the development of cancer vaccines, but many antigens lack immunogenicity. Adjuvants are added to vaccine formulations to trigger immune responses. Aging can lead to immunosenescence and chronic inflammation.

FRONTIERS IN IMMUNOLOGY (2021)

Add to Collection
Article Immunology

Manganese salts function as potent adjuvants

Rui Zhang et al.

Summary: The colloidal manganese salt (Mn jelly, MnJ) acts as both an immune potentiator and a delivery system, promoting immune responses by inducing antibody production and CD4(+)/CD8(+) T-cell proliferation and activation. It also shows promise as a mucosal adjuvant, inducing high levels of secretory IgA and proving effective for various antigens, making it a potential candidate for adjuvant use.

CELLULAR & MOLECULAR IMMUNOLOGY (2021)

Add to Collection
Review Pharmacology & Pharmacy

Iron nanoparticles as novel vaccine adjuvants

Maryam Behzadi et al.

Summary: Recent studies have shown that metallic nanoparticles have great potential as novel vaccine adjuvants to improve immune responses. Iron nanoparticles, as an important category of metallic nanoparticles, have gained increasing attention as novel vaccine adjuvants with acceptable results in preclinical studies. Understanding the physicochemical properties of iron nanoparticles is crucial for their research and application as novel vaccine adjuvants.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

Add to Collection
Review Pharmacology & Pharmacy

Metallic Nanoparticle-Mediated Immune Cell Regulation and Advanced Cancer Immunotherapy

Adityanarayan Mohapatra et al.

Summary: Cancer immunotherapy harnesses the body's immune system against cancer cells but faces challenges of immunosuppression and limited antitumor immunity. Metallic nanoparticles show promise as anticancer agents, with unique properties for targeting tumors and modulating the tumor microenvironment.

PHARMACEUTICS (2021)

Add to Collection
Review Biotechnology & Applied Microbiology

Emerging concepts in the science of vaccine adjuvants

Bali Pulendran et al.

Summary: Adjuvants are vaccine components that enhance the immune response. Recent advances in understanding the molecular mechanisms and systems vaccinology have revitalized the science and development of novel adjuvants for use in vaccines against COVID-19 and future pandemics.

NATURE REVIEWS DRUG DISCOVERY (2021)

Add to Collection
Review Immunology

Cancer Vaccines, Adjuvants, and Delivery Systems

Samantha J. Paston et al.

Summary: Vaccination has had a significant impact in preventing infectious diseases, but the development of therapeutic cancer vaccines has been challenging.

FRONTIERS IN IMMUNOLOGY (2021)

Add to Collection
Article Immunology

Nanoparticles for Enhanced Adoptive T Cell Therapies and Future Perspectives for CNS Tumors

Preethi Bala Balakrishnan et al.

Summary: Nanoparticles have the potential to overcome limitations of T cell therapy in treating solid tumors by activating T cells ex vivo, encapsulating stimulating agents for co-localized stimulation, and conjugating onto T cells for added functionality.

FRONTIERS IN IMMUNOLOGY (2021)

Add to Collection
Review Chemistry, Multidisciplinary

Progress in Light-Responsive Lanthanide Nanoparticles toward Deep Tumor Theranostics

Jie Yan et al.

Summary: Lanthanide nanoparticles have excellent photoresponsive performance for deep-seated tumors, making them efficient for cancer treatment and imaging, but there are still challenges in translating them to clinical applications.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection
Article Oncology

Mapping of truncated O-glycans in cancers of epithelial and non-epithelial origin

Troels Boldt Romer et al.

Summary: Novel immunotherapies targeting cancer-associated truncated O-glycans Tn and STn show promise in cancer treatment, with surface expression limited to cancers of epithelial origin. Tn and STn expression levels decrease with tumor grade, making them attractive immunological targets for human carcinomas. Patient-derived xenografts have shown to maintain Tn expression, highlighting the potential for targeting these glycan antigens in cancer therapy.

BRITISH JOURNAL OF CANCER (2021)

Add to Collection
Review Biochemistry & Molecular Biology

Step-by-Step Immune Activation for Suicide Gene Therapy Reinforcement

Irina Alekseenko et al.

Summary: Gene-directed enzyme prodrug gene therapy (GDEPT) is a promising method of chemotherapy for cancer with minimal side effects, but has not yet reached clinical application after over 25 years of research. Combination therapies incorporating immunomodulators alongside traditional methods like chemotherapy and radiotherapy, as well as GDEPT, may generate robust tumor-specific immune responses and show great potential in cancer treatment. Expanding research into immunotherapy and exploring the use of danger signals to enhance immune responses within tumors are important considerations for improving cancer therapy outcomes.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection
Review Chemistry, Multidisciplinary

Recent progress in stimuli-responsive nanosystems for inducing immunogenic cell death

Asmita Banstola et al.

Summary: It has been found that low immunogenicity and immunosuppressive tumor microenvironments are significant obstacles to the application of cancer immunotherapy. Researchers are exploring the use of stimuli-responsive nanoparticles to improve cancer immunotherapy in order to overcome these challenges.

JOURNAL OF CONTROLLED RELEASE (2021)

Add to Collection
Review Biochemistry & Molecular Biology

Nanoparticle-Mediated STING Agonist Delivery for Enhanced Cancer Immunotherapy

Qinghao Zhou et al.

Summary: STING agonists have shown promise in cancer immunotherapy, but the limitations of small molecule agonists and physiological barriers for in vivo activation hinder their therapeutic efficacy. Drug delivery systems are crucial for enhancing STING activation efficiency in targeting tissues.

MACROMOLECULAR BIOSCIENCE (2021)

Add to Collection
Article Oncology

Elesclomol induces copper-dependent ferroptosis in colorectal cancer cells via degradation of ATP7A

Wei Gao et al.

Summary: Elesclomol inhibits colorectal cancer by inducing copper overload, promoting oxidative stress, and regulating ferroptosis through targeting ATP7A.

MOLECULAR ONCOLOGY (2021)

Add to Collection
Article Chemistry, Multidisciplinary

Reinforcing the Induction of Immunogenic Cell Death Via Artificial Engineered Cascade Bioreactor-Enhanced Chemo-Immunotherapy for Optimizing Cancer Immunotherapy

Kai Sun et al.

Summary: Traditional chemo-immunotherapy can induce T cell immune response through immunogenic cell death (ICD), but the limited ICD hinders lasting antitumor immunotherapeutic efficacy. A novel tadpole-ovoid Au@HMnMSNs nanoreactor is constructed to generate intratumoral hydroxyl radicals for enhanced ICD induction and DC maturation, along with DOX and ASA for recruitment of immune cells and inhibition of immunosuppressive cells.

SMALL (2021)

Add to Collection
Review Pharmacology & Pharmacy

Mimicking Pathogens to Augment the Potency of Liposomal Cancer Vaccines

Maarten K. Nijen Twilhaar et al.

Summary: Liposomes have potential as vehicles for cancer vaccines, but their full efficacy has not yet been realized in clinical applications. Recent preclinical studies have summarized the basic components, targeting strategies, and antigen-presenting cells that may enhance the effectiveness of liposomal cancer vaccines.

PHARMACEUTICS (2021)

Add to Collection
Review Biotechnology & Applied Microbiology

Stimuli-Responsive Polymeric Nanoplatforms for Cancer Therapy

Di Chang et al.

Summary: Polymeric nanoparticles are widely used as carriers in medicine, especially in cancer therapy, due to their biocompatibility and ability to respond to stimuli conditions. Stimuli-responsive polymeric nanoplatforms have the potential to significantly improve the effectiveness of cancer treatment by changing physicochemical properties in target tissues.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

Add to Collection
Review Nanoscience & Nanotechnology

Multifunctional Gold Nanoparticles for Improved Diagnostic and Therapeutic Applications: A Review

Nicole Remaliah Samantha Sibuyi et al.

Summary: The medical properties of metals have been explored for centuries and metal nanoparticles like AuNPs have shown great potential in various medical applications. They have unique properties compared to their bulk counterparts and are used in drug delivery, photothermal therapy, contrast agents, therapeutic agents, radiosensitizers, and gene transfection agents in medicine. AuNP-based systems have shown promise in improving efficacy in disease diagnosis and therapy, and strategies to improve their biocompatibility are being explored.

NANOSCALE RESEARCH LETTERS (2021)

Add to Collection
Article Chemistry, Multidisciplinary

Immunogenic cell death inducers for enhanced cancer immunotherapy

Yanhua Li et al.

Summary: The article highlights the importance of inducing immunogenic cell death (ICD) of cancer cells and discusses strategies and inducers to trigger ICD for enhanced cancer immunotherapy. It aims to inspire readers to develop more effective ICD inducers.

CHEMICAL COMMUNICATIONS (2021)

Add to Collection
Review Biochemistry & Molecular Biology

Pattern recognition receptors in health and diseases

Danyang Li et al.

Summary: Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize specific molecular structures on pathogens, apoptotic host cells, and damaged senescent cells, bridging nonspecific immunity and specific immunity. Through the recognition and binding of ligands, PRRs can produce immunoprotective effects against infections and tumors. Research on PRRs and their ligands has greatly enhanced understanding of the signaling pathways involved, providing insights for the treatment of immune-related diseases and tumors.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)

Add to Collection
Review Chemistry, Physical

Iron oxide nanoparticles for immune cell labeling and cancer immunotherapy

Seokhwan Chung et al.

Summary: Cancer immunotherapy utilizes components of the immune system for treatment, with cell migration playing a crucial role in therapeutic immune response. Iron oxide nanoparticles (IONPs) show promise for use in contrast-enhanced MRI in tracking immune cells. Advances in IONPs application in cell tracking and cancer immunotherapy, as well as factors affecting their effectiveness as MRI contrast agents, are discussed.

NANOSCALE HORIZONS (2021)

Add to Collection
Review Cell Biology

Nanoparticles and cancer therapy: Perspectives for application of nanoparticles in the treatment of cancers

Ali Aghebati-Maleki et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Z-Scheme Heterojunction Functionalized Pyrite Nanosheets for Modulating Tumor Microenvironment and Strengthening Photo/Chemodynamic Therapeutic Effects

Chao Pan et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Add to Collection
Article Oncology

Intratumoral Immunotherapy-Update 2019

Omid Hamid et al.

ONCOLOGIST (2020)

Add to Collection
Review Oncology

Intratumoral Immunotherapy for Early-stage Solid Tumors

Wan Xing Hong et al.

CLINICAL CANCER RESEARCH (2020)

Add to Collection
Article Immunology

Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization

Caitlin D. Lemke-Miltner et al.

JOURNAL OF IMMUNOLOGY (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Engineering of Upconverted Metal-Organic Frameworks for Near-Infrared Light-Triggered Combinational Photodynamic/Chemo-/Immunotherapy against Hypoxic Tumors

Yulei Shao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Add to Collection
Review Chemistry, Medicinal

Agonists and inhibitors of the STING pathway: Potential agents for immunotherapy

Jun-Jun Wu et al.

MEDICINAL RESEARCH REVIEWS (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Gold Nanoparticles in Conjunction with Nucleic Acids as a Modern Molecular System for Cellular Delivery

Anna Graczyk et al.

MOLECULES (2020)

Add to Collection
Article Chemistry, Physical

The entry of nanoparticles into solid tumours

Shrey Sindhwani et al.

NATURE MATERIALS (2020)

Add to Collection
Article Engineering, Biomedical

Nitinol thin films functionalized with CAR-T cells for the treatment of solid tumours

Michael E. Coon et al.

NATURE BIOMEDICAL ENGINEERING (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Manganese-Based Nanoactivator Optimizes Cancer Immunotherapy via Enhancing Innate Immunity

Lin Hou et al.

ACS NANO (2020)

Add to Collection
Article Multidisciplinary Sciences

Validation of MRI quantitative susceptibility mapping of superparamagnetic iron oxide nanoparticles for hyperthermia applications in live subjects

Kofi Deh et al.

SCIENTIFIC REPORTS (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Mitochondria Targeting as an Effective Strategy for Cancer Therapy

Poorva Ghosh et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection
Review Engineering, Biomedical

Magnetic Nanoparticles in Cancer Therapy and Diagnosis

Ali Farzin et al.

ADVANCED HEALTHCARE MATERIALS (2020)

Add to Collection
Article Nanoscience & Nanotechnology

Induction of antitumor immunity in mice by the combination of nanoparticle-based photothermolysis and anti-PD-1 checkpoint inhibition

Qizhen Cao et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2020)

Add to Collection
Review Immunology

Better Adjuvants for Better Vaccines: Progress in Adjuvant Delivery Systems, Modifications, and Adjuvant-Antigen Codelivery

Zhi-Biao Wang et al.

VACCINES (2020)

Add to Collection
Review Pharmacology & Pharmacy

Cancer therapy with iron oxide nanoparticles: Agents of thermal and immune therapies

Frederik Soetaert et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

Add to Collection
Review Chemistry, Multidisciplinary

Recent Advances of Gold Compounds in Anticancer Immunity

Shuang Yue et al.

FRONTIERS IN CHEMISTRY (2020)

Add to Collection
Review Chemistry, Multidisciplinary

Emerging Adjuvants for Cancer Immunotherapy

Hong-Guo Hu et al.

FRONTIERS IN CHEMISTRY (2020)

Add to Collection
Article Multidisciplinary Sciences

A reanalysis of nanoparticle tumor delivery using classical pharmacokinetic metrics

Lauren S. L. Price et al.

SCIENCE ADVANCES (2020)

Add to Collection
Article Oncology

Overall survival at 5 years of follow-up in a phase III trial comparing ipilimumab 10 mg/kg with 3 mg/kg in patients with advanced melanoma

Paolo Antonio Ascierto et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)

Add to Collection
Review Oncology

Mitochondrial metabolism and cancer metastasis

Dandan Yu et al.

ANNALS OF TRANSLATIONAL MEDICINE (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Albumin-biomineralized nanoparticles to synergize phototherapy and immunotherapy against melanoma

Yining Zhu et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Add to Collection
Article Oncology

Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion

Florida Voli et al.

CANCER RESEARCH (2020)

Add to Collection
Article Cell Biology

Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy

Mengze Lv et al.

CELL RESEARCH (2020)

Add to Collection
Review Immunology

The NK cell-cancer cycle: advances and new challenges in NK cell-based immunotherapies

Tobias Bald et al.

NATURE IMMUNOLOGY (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Functionalized Gold Nanoparticles: Synthesis, Properties and Biomedical Applications

Jianuo Fan et al.

CHEMICAL RECORD (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Redox Responsive Metal Organic Framework Nanoparticles Induces Ferroptosis for Cancer Therapy

Haozhe He et al.

SMALL (2020)

Add to Collection
Article Chemistry, Multidisciplinary

Tumor cell membrane enveloped aluminum phosphate nanoparticles for enhanced cancer vaccination

Jingyao Gan et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Add to Collection
Review Immunology

Poly-ICLC, a multi-functional immune modulator for treating cancer

Hussein Sultan et al.

SEMINARS IN IMMUNOLOGY (2020)

Add to Collection
Review Immunology

The Use of Immune Checkpoint Inhibitors in Oncology and the Occurrence of AKI: Where Do We Stand?

Rossana Franzin et al.

FRONTIERS IN IMMUNOLOGY (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Aptamer-Functionalized Nanoparticles in Targeted Delivery and Cancer Therapy

Zhaoying Fu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection
Review Immunology

Therapeutic strategies to remodel immunologically cold tumors

Minyu Wang et al.

CLINICAL & TRANSLATIONAL IMMUNOLOGY (2020)

Add to Collection
Article Oncology

Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity

Iuliia Efimova et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)

Add to Collection
Review Chemistry, Multidisciplinary

Role of gold nanoparticles in advanced biomedical applications

Suneev Anil Bansal et al.

NANOSCALE ADVANCES (2020)

Add to Collection
Letter Biochemistry & Molecular Biology

Use of copper-cysteamine nanoparticles to simultaneously enable radiotherapy, oxidative therapy and immunotherapy for melanoma treatment

Qi Zhang et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

Add to Collection
Review Oncology

The cancer-natural killer cell immunity cycle

Nicholas D. Huntington et al.

NATURE REVIEWS CANCER (2020)

Add to Collection
Review Chemistry, Inorganic & Nuclear

Lanthanide conjugates as versatile instruments for therapy and diagnostics

Claudine Herlan et al.

DALTON TRANSACTIONS (2020)

Add to Collection
Editorial Material Nanoscience & Nanotechnology

Opening the vascular gate

Tsveta S. Malinova et al.

NATURE NANOTECHNOLOGY (2019)

Add to Collection
Article Nanoscience & Nanotechnology

FDA-approved ferumoxytol displays anti-leukaemia efficacy against cells with low ferroportin levels

Vicenta Trujillo-Alonso et al.

NATURE NANOTECHNOLOGY (2019)

Add to Collection
Review Chemistry, Multidisciplinary

Combining Nanomedicine and Immunotherapy

Yang Shi et al.

ACCOUNTS OF CHEMICAL RESEARCH (2019)

Add to Collection
Article Chemistry, Multidisciplinary

Engineering Magnetosomes for Ferroptosis/Immunomodulation Synergism in Cancer

Fan Zhang et al.

ACS NANO (2019)

Add to Collection
Article Chemistry, Multidisciplinary

An aluminum adjuvant-integrated nano-MOF as antigen delivery system to induce strong humoral and cellular immune responses

Xiaofang Zhong et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Add to Collection
Article Chemistry, Multidisciplinary

Mechanism of Iron Oxide-Induced Macrophage Activation: The Impact of Composition and the Underlying Signaling Pathway

Zhengying Gu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Mitochondrial metabolism promotes adaptation to proteotoxic stress

Peter Tsvetkov et al.

NATURE CHEMICAL BIOLOGY (2019)

Add to Collection
Article Multidisciplinary Sciences

Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors

Xiaopin Duan et al.

NATURE COMMUNICATIONS (2019)

Add to Collection
Review Immunology

Complementing the Cancer-Immunity Cycle

Ruben Pio et al.

FRONTIERS IN IMMUNOLOGY (2019)

Add to Collection
Article Biophysics

Stabilised aluminium phosphate nanoparticles used as vaccine adjuvant

Hilde Vrieling et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2019)

Add to Collection
Article Biotechnology & Applied Microbiology

In vivo molecular imaging for immunotherapy using ultra-bright near-infrared-IIb rare-earth nanoparticles

Yeteng Zhong et al.

NATURE BIOTECHNOLOGY (2019)

Add to Collection
Article Immunology

Magnetic Nanoparticles Attached to the NK Cell Surface for Tumor Targeting in Adoptive Transfer Therapies Does Not Affect Cellular Effector Functions

Laura Sanz-Ortega et al.

FRONTIERS IN IMMUNOLOGY (2019)

Add to Collection
Article Chemistry, Multidisciplinary

Dendritic Cell-Activating Magnetic Nanoparticles Enable Early Prediction of Antitumor Response with Magnetic Resonance Imaging

Adam J. Grippin et al.

ACS NANO (2019)

Add to Collection
Article Nanoscience & Nanotechnology

Functionalization Of T Lymphocytes With Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles For Magnetically Controlled Immune Therapy

Marina Muehlberger et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Add to Collection
Review Chemistry, Multidisciplinary

Plasmonic gold nanoparticles: Optical manipulation, imaging, drug delivery and therapy

Majid Sharifi et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Add to Collection
Article Biotechnology & Applied Microbiology

AuNPs as an important inorganic nanoparticle applied in drug carrier systems

Wen Li et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2019)

Add to Collection
Article Nanoscience & Nanotechnology

Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy

Daniel Shae et al.

NATURE NANOTECHNOLOGY (2019)

Add to Collection
Review Biotechnology & Applied Microbiology

Delivery technologies for cancer immunotherapy

Rachel S. Riley et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

Add to Collection
Article Biotechnology & Applied Microbiology

T cells loaded with magnetic nanoparticles are retained in peripheral lymph nodes by the application of a magnetic field

Laura Sanz-Ortega et al.

JOURNAL OF NANOBIOTECHNOLOGY (2019)

Add to Collection
Review Immunology

Vaccine Strategies to Improve Anti-cancer Cellular Immune Responses

Karim Vermaelen

FRONTIERS IN IMMUNOLOGY (2019)

Add to Collection
Article Immunology

Reprogramming the adjuvant properties of aluminum oxyhydroxide with nanoparticle technology

Mark T. Orr et al.

NPJ VACCINES (2019)

Add to Collection
Article Chemistry, Multidisciplinary

Surgical Tumor-Derived Personalized Photothermal Vaccine Formulation for Cancer Immunotherapy

Xinyu Ye et al.

ACS NANO (2019)

Add to Collection
Article Medicine, Research & Experimental

A tumor microenvironment responsive biodegradable CaCO3/MnO2- based nanoplatform for the enhanced photodynamic therapy and improved PD-L1 immunotherapy

Yanlei Liu et al.

THERANOSTICS (2019)

Add to Collection
Review Pharmacology & Pharmacy

Recent advances in metal nanoparticles in cancer therapy

Ankush Sharma et al.

JOURNAL OF DRUG TARGETING (2018)

Add to Collection
Review Materials Science, Multidisciplinary

Metallic nanoparticles for cancer immunotherapy

Emily Reiser Evans et al.

MATERIALS TODAY (2018)

Add to Collection
Article Chemistry, Multidisciplinary

Turning the Old Adjuvant from Gel to Nanoparticles to Amplify CD8(+) T Cell Responses

Hao Jiang et al.

ADVANCED SCIENCE (2018)

Add to Collection
Article Chemistry, Multidisciplinary

Simultaneous Fenton-like Ion Delivery and Glutathione Depletion by MnO2-Based Nanoagent to Enhance Chemodynamic Therapy

Li-Sen Lin et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Add to Collection
Article Biophysics

Gold nanoparticles functionalized with angiogenin-mimicking peptides modulate cell membrane interactions

Lorena M. Cucci et al.

BIOINTERPHASES (2018)

Add to Collection
Letter Immunology

Anticancer efficacy of noble metal nanoparticles relies on reprogramming tumor-associated macrophages through redox pathways and pro-inflammatory cytokine cascades

Mahuya Sengupta et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2018)

Add to Collection
Review Chemistry, Multidisciplinary

Metal-organic framework-based materials: superior adsorbents for the capture of toxic and radioactive metal ions

Jie Li et al.

CHEMICAL SOCIETY REVIEWS (2018)

Add to Collection
Article Immunology

Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses

Chenguang Wang et al.

IMMUNITY (2018)

Add to Collection
Article Medicine, Research & Experimental

Iron Oxide Nanoparticles-Based Vaccine Delivery for Cancer Treatment

Yi Zhao et al.

MOLECULAR PHARMACEUTICS (2018)

Add to Collection
Review Chemistry, Multidisciplinary

Recent advances in functional nanomaterials for light-triggered cancer therapy

Shili Gai et al.

NANO TODAY (2018)

Add to Collection
Review Biochemistry & Molecular Biology

Understanding the tumor immune microenvironment (TIME) for effective therapy

Mikhail Binnewies et al.

NATURE MEDICINE (2018)

Add to Collection
Article Biophysics

Gold nanoparticles functionalized with angiogenin-mimicking peptides modulate cell membrane interactions

Lorena M. Cucci et al.

BIOINTERPHASES (2018)

Add to Collection
Article Medicine, Research & Experimental

O-2-generating MnO2 nanoparticles for enhanced photodynamic therapy of bladder cancer by ameliorating hypoxia

Tingsheng Lin et al.

THERANOSTICS (2018)

Add to Collection
Article Pharmacology & Pharmacy

Mechanistic study of the adjuvant effect of chitosan-aluminum nanoparticles

F. Lebre et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

Add to Collection
Article Multidisciplinary Sciences

Radioactive (Y-90) upconversion nanoparticles conjugated with recombinant targeted toxin for synergistic nanotheranostics of cancer

Evgenii L. Guryev et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Add to Collection
Article Materials Science, Biomaterials

Magnetic delivery of Fe3O4@polydopamine nanoparticle-loaded natural killer cells suggest a promising anticancer treatment

Liya Wu et al.

BIOMATERIALS SCIENCE (2018)

Add to Collection
Article Nanoscience & Nanotechnology

Physical activation of innate immunity by spiky particles

Ji Wang et al.

NATURE NANOTECHNOLOGY (2018)

Add to Collection
Review Immunology

Pattern Recognition Receptors and the Host Cell Death Molecular Machinery

Gustavo P. Amarante-Mendes et al.

FRONTIERS IN IMMUNOLOGY (2018)

Add to Collection
Review Immunology

Cancer immunotherapy: A need for peripheral immunodynamic monitoring

Wenjun Wang et al.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2018)

Add to Collection
Review Oncology

Using immunotherapy to boost the abscopal effect

Wilfred Ngwa et al.

NATURE REVIEWS CANCER (2018)

Add to Collection
Review Immunology

Intratumoral Delivery of Immunotherapy-Act Locally, Think Globally

M. Angela Aznar et al.

JOURNAL OF IMMUNOLOGY (2017)

Add to Collection
Article Pharmacology & Pharmacy

Immunomodulatory properties of titanium dioxide nanostructural materials

T. Sree Latha et al.

INDIAN JOURNAL OF PHARMACOLOGY (2017)

Add to Collection
Article Nanoscience & Nanotechnology

Enhancement of the Immune Function by Titanium Dioxide Nanorods and Their Application in Cancer Immunotherapy

Yanli Wang et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2017)

Add to Collection
Article Materials Science, Biomaterials

Near-infrared mediated chemo/photodynamic synergistic therapy with DOX-UCNPs@mSiO2/TiO2-TC nanocomposite

Ruihan Tong et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

Add to Collection
Article Multidisciplinary Sciences

Cytotoxic effect of albumin coated copper nanoparticle on human breast cancer cells of MDA-MB 231

Marzieh Azizi et al.

PLOS ONE (2017)

Add to Collection
Article Multidisciplinary Sciences

Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses

Guangbao Yang et al.

NATURE COMMUNICATIONS (2017)

Add to Collection
Article Medicine, Research & Experimental

Radionuclide I-131 Labeled Albumin-Paclitaxel Nanoparticles for Synergistic Combined Chemo-radioisotope Therapy of Cancer

Longlong Tian et al.

THERANOSTICS (2017)

Add to Collection
Review Immunology

Why the Immune System Should Be Concerned by Nanomaterials?

Marc J. Pallardy et al.

FRONTIERS IN IMMUNOLOGY (2017)

Add to Collection
Review Biochemistry & Molecular Biology

Gold Nanoparticles: Promising Agent to Improve the Diagnosis and Therapy of Cancer

Limin Ning et al.

CURRENT DRUG METABOLISM (2017)

Add to Collection
Review Oncology

Intratumoral immunotherapy: using the tumor as the remedy

A. Marabelle et al.

ANNALS OF ONCOLOGY (2017)

Add to Collection
Review Oncology

Cancer nanomedicine: progress, challenges and opportunities

Jinjun Shi et al.

NATURE REVIEWS CANCER (2017)

Add to Collection
Article Oncology

Correlation between Ferumoxytol Uptake in Tumor Lesions by MRI and Response to Nanoliposomal Irinotecan in Patients with Advanced Solid Tumors: A Pilot Study

Ramesh K. Ramanathan et al.

CLINICAL CANCER RESEARCH (2017)

Add to Collection
Article Chemistry, Multidisciplinary

Metal-Organic Framework (MOF)-Based Drug/Cargo Delivery and Cancer Therapy

Ming-Xue Wu et al.

ADVANCED MATERIALS (2017)

Add to Collection
Article Biophysics

Near-infrared light-mediated DOX-UCNPs@mHTiO2 nanocomposite for chemo/photodynamic therapy and imaging

Yuhua Chen et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2017)

Add to Collection
Review Pharmacology & Pharmacy

Delivering safer immunotherapies for cancer

Lauren Milling et al.

ADVANCED DRUG DELIVERY REVIEWS (2017)

Add to Collection
Article Chemistry, Multidisciplinary

Near-Infrared-Triggered Photodynamic Therapy with Multitasking Upconversion Nanoparticles in Combination with Checkpoint Blockade for Immunotherapy of Colorectal Cancer

Jun Xu et al.

ACS NANO (2017)

Add to Collection
Article Chemistry, Applied

Thermal and magnetic properties of chitosan-iron oxide nanoparticles

Paula I. P. Soares et al.

CARBOHYDRATE POLYMERS (2016)

Add to Collection
Review Chemistry, Multidisciplinary

Cu and Cu-Based Nanoparticles: Synthesis and Applications in Review Catalysis

Manoj B. Gawande et al.

CHEMICAL REVIEWS (2016)

Add to Collection
Article Biotechnology & Applied Microbiology

Cytotoxicity of gold nanoparticles in human neural precursor cells and rat cerebral cortex

Uhn Lee et al.

JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2016)

Add to Collection
Review Hematology

A Retrospective 30Years After Discovery of the Enhanced Permeability and Retention Effect of Solid Tumors: Next-Generation Chemotherapeutics and Photodynamic TherapyProblems, Solutions, and Prospects

Hiroshi Maeda et al.

MICROCIRCULATION (2016)

Add to Collection
Review Biochemistry & Molecular Biology

The cause of cancer mutations: Improvable bad life or inevitable stochastic replication errors?

I. V. Alekseenko et al.

MOLECULAR BIOLOGY (2016)

Add to Collection
Article Nanoscience & Nanotechnology

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

Saeid Zanganeh et al.

NATURE NANOTECHNOLOGY (2016)

Add to Collection
Article Oncology

How Cancers Escape Immune Destruction and Mechanisms of Action for the New Significantly Active Immune Therapies: Helping Nonimmunologists Decipher Recent Advances

Jonathan L. Messerschmidt et al.

ONCOLOGIST (2016)

Add to Collection
Article Multidisciplinary Sciences

ROS-generating TiO2 nanoparticles for non-invasive sonodynamic therapy of cancer

Dong Gil You et al.

SCIENTIFIC REPORTS (2016)

Add to Collection
Review Oncology

Immunodynamics: a cancer immunotherapy trials network review of immune monitoring in immuno-oncology clinical trials

Holbrook E. Kohrt et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2016)

Add to Collection
Article Chemistry, Multidisciplinary

Antigen-Loaded Upconversion Nanoparticles for Dendritic Cell Stimulation, Tracking, and Vaccination in Dendritic Cell-Based Immunotherapy

Jian Xiang et al.

ACS NANO (2015)

Add to Collection
Article Chemistry, Multidisciplinary

Imaging-Guided Combined Photothermal and Radiotherapy to Treat Subcutaneous and Metastatic Tumors Using Iodine-131-Doped Copper Sulfide Nanoparticles

Xuan Yi et al.

ADVANCED FUNCTIONAL MATERIALS (2015)

Add to Collection
Review Biochemistry & Molecular Biology

Magnetic nanoparticle-based drug delivery for cancer therapy

Rainer Tietze et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

Add to Collection
Article Engineering, Biomedical

Gold nanoparticles with different charge and moiety induce differential cell response on mesenchymal stem cell osteogenesis

Jia'En Jasmine Li et al.

BIOMATERIALS (2015)

Add to Collection
Article Biochemistry & Molecular Biology

Doxorubicin loaded polymeric gold nanoparticles targeted to human folate receptor upon laser photothermal therapy potentiates chemotherapy in breast cancer cell lines

Hussaina Banu et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2015)

Add to Collection
Article Medicine, Research & Experimental

Therapeutic properties of a vector carrying the HSV thymidine kinase and GM-CSF genes and delivered as a complex with a cationic copolymer

Irina V. Alekseenko et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2015)

Add to Collection
Review Oncology

In situ vaccination: Cancer immunotherapy both personalized and off-the-shelf

Linda Hammerich et al.

MOLECULAR ONCOLOGY (2015)

Add to Collection
Article Nanoscience & Nanotechnology

Nanoparticles in medicine: Current challenges facing inorganic nanoparticle toxicity assessments and standardizations

Margarethe Hofmann-Amtenbrink et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)

Add to Collection
Article Nanoscience & Nanotechnology

Thermal and magnetic properties of iron oxide colloids: influence of surfactants

Paula I. P. Soares et al.

NANOTECHNOLOGY (2015)

Add to Collection
Article Cell Biology

Cancer Therapeutic Effects of Titanium Dioxide Nanoparticies Are Associated with Oxidative Stress and Cytokine induction

Rina Fujiwara et al.

PATHOBIOLOGY (2015)

Add to Collection
Review Multidisciplinary Sciences

Nonadditivity of nanoparticle interactions

Carlos A. Silvera Batista et al.

SCIENCE (2015)

Add to Collection
Review Biotechnology & Applied Microbiology

Advances in aluminum hydroxide-based adjuvant research and its mechanism

Peng He et al.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2015)

Add to Collection
Review Biotechnology & Applied Microbiology

Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications

Yueh-Hsia Luo et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Add to Collection
Article Oncology

In Vitro Administration of Gold Nanoparticles Functionalized with MUC-1 Protein Fragment Generates Anticancer Vaccine Response via Macrophage Activation and Polarization Mechanism

Teodora Mocan et al.

JOURNAL OF CANCER (2015)

Add to Collection
Article Materials Science, Biomaterials

The enhanced chemotherapeutic effects of doxorubicin loaded PEG coated TiO2 nanocarriers in an orthotopic breast tumor bearing mouse model

Yang Du et al.

JOURNAL OF MATERIALS CHEMISTRY B (2015)

Add to Collection
Review Immunology

Vaccine adjuvant uses of poly-IC and derivatives

Karen Ao Martins et al.

EXPERT REVIEW OF VACCINES (2015)

Add to Collection
Article Chemistry, Multidisciplinary

In vivo Gold Nanoparticle Delivery of Peptide Vaccine Induces Anti-Tumor Immune Response in Prophylactic and Therapeutic Tumor Models

Joao Paulo Mattos Almeida et al.

SMALL (2015)

Add to Collection
Article

Using quantitative proteomic analysis to understand genotype specific intrinsic drug resistance in melanoma

John M. Koomen et al.

Oncotarget (2015)

Add to Collection
Review Chemistry, Multidisciplinary

EPR: Evidence and fallacy

Joseph W. Nichols et al.

JOURNAL OF CONTROLLED RELEASE (2014)

Add to Collection
Article Chemistry, Medicinal

Enhanced Mucosal Immune Responses Against Tetanus Toxoid Using Novel Delivery System Comprised of Chitosan-Functionalized Gold Nanoparticles and Botanical Adjuvant: Characterization, Immunogenicity, and Stability Assessment

Ganesh Barhate et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2014)

Add to Collection
Review Nanoscience & Nanotechnology

Gold nanoparticle mediated cancer immunotherapy

Joao Paulo Mattos Almeida et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2014)

Add to Collection
Article Chemistry, Multidisciplinary

A general mechanism for intracellular toxicity of metal-containing nanoparticles

Stefania Sabella et al.

NANOSCALE (2014)

Add to Collection
Article Nanoscience & Nanotechnology

Gold nanoparticles cellular toxicity and recovery: Adipose Derived Stromal cells

Tatsiana Mironava et al.

NANOTOXICOLOGY (2014)

Add to Collection
Article Multidisciplinary Sciences

Probing the inherent stability of siRNA immobilized on nanoparticle constructs

Stacey N. Barnaby et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Add to Collection
Article Biochemistry & Molecular Biology

Memo Is a Copper-Dependent Redox Protein with an Essential Role in Migration and Metastasis

Gwen MacDonald et al.

SCIENCE SIGNALING (2014)

Add to Collection
Review Biotechnology & Applied Microbiology

Recent progress in adjuvant discovery for peptide-based subunit vaccines

Fazren Azmi et al.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2014)

Add to Collection
Review Immunology

Oncology Meets Immunology: The Cancer-Immunity Cycle

Daniel S. Chen et al.

IMMUNITY (2013)

Add to Collection
Article Pharmacology & Pharmacy

Quillaja saponaria extract as mucosal adjuvant with chitosan functionalized gold nanoparticles for mucosal vaccine delivery: Stability and immunoefficiency studies

Ganesh Barhate et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)

Add to Collection
Article Toxicology

Toxicity assessment of manganese oxide micro and nanoparticles in Wistar rats after 28days of repeated oral exposure

Shailendra Pratap Singh et al.

JOURNAL OF APPLIED TOXICOLOGY (2013)

Add to Collection
Article Chemistry, Multidisciplinary

'Multicopy Multivalent' Glycopolymer-Stabilized Gold Nanoparticles as Potential Synthetic Cancer Vaccines

Alison L. Parry et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Add to Collection
Article Toxicology

Iron oxide particles modulate the ovalbumin-induced Th2 immune response in mice

Masarin Ban et al.

TOXICOLOGY LETTERS (2013)

Add to Collection
Review Immunology

Mechanisms of action of adjuvants

Sunita Awate et al.

FRONTIERS IN IMMUNOLOGY (2013)

Add to Collection
Article Toxicology

Intestinal toxicity evaluation of TiO2 degraded surface-treated nanoparticles: a combined physico-chemical and toxicogenomics approach in caco-2 cells

Matthieu Fisichella et al.

PARTICLE AND FIBRE TOXICOLOGY (2012)

Add to Collection
Review Immunology

Natural Innate and Adaptive Immunity to Cancer

Matthew D. Vesely et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 29 (2011)

Add to Collection
Article Chemistry, Multidisciplinary

Nanoporous TiO2 spheres with narrow pore size distribution and improved visible light photocatalytic abilities

Hai Ming et al.

CHEMICAL COMMUNICATIONS (2011)

Add to Collection
Article Chemistry, Multidisciplinary

Surface charge of gold nanoparticles mediates mechanism of toxicity

Nicole M. Schaeublin et al.

NANOSCALE (2011)

Add to Collection
Article Pharmacology & Pharmacy

Nano Titanium Dioxide Particles Promote Allergic Sensitization and Lung Inflammation in Mice

Soren T. Larsen et al.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2010)

Add to Collection
Article Biochemistry & Molecular Biology

Over-expression of ST3Gal-I promotes mammary tumorigenesis

Gianfranco Picco et al.

GLYCOBIOLOGY (2010)

Add to Collection
Article Immunology

MUC1 immunotherapy

Richard E. Beatson et al.

IMMUNOTHERAPY (2010)

Add to Collection
Article Chemistry, Multidisciplinary

The Immunotherapeutic Effect of Fe3O4 Nanoparticles as Adjuvants on Mice H-22 Live Cancer

Hui Liu et al.

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2010)

Add to Collection
Article Pharmacology & Pharmacy

Engineered nanornaterials cause cytotoxicity and activation on mouse antigen presenting cells

J. Palomaki et al.

TOXICOLOGY (2010)

Add to Collection
Review Chemistry, Multidisciplinary

Immunotherapy for cancer: synthetic carbohydrate-based vaccines

Therese Buskas et al.

CHEMICAL COMMUNICATIONS (2009)

Add to Collection
Review Pharmacology & Pharmacy

The Immunomodulatory Role of Angiocidin, a Novel Angiogenesis Inhibitor

A. Gaurnier-Hausser et al.

CURRENT PHARMACEUTICAL DESIGN (2009)

Add to Collection
Article Immunology

Towards an understanding of the adjuvant action of aluminium

Philippa Marrack et al.

NATURE REVIEWS IMMUNOLOGY (2009)

Add to Collection
Editorial Material Immunology

Alum adjuvanticity: Unraveling a century old mystery

Ennio De Gregorio et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2008)

Add to Collection
Article Urology & Nephrology

Ferumoxytol for Treating Iron Deficiency Anemia in CKD

Bruce S. Spinowitz et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)

Add to Collection
Article Toxicology

Tissue distribution and toxicity of intravenously administered titanium dioxide nanoparticles in rats

Eric Fabian et al.

ARCHIVES OF TOXICOLOGY (2008)

Add to Collection
Review Oncology

The concurrent chemoradiation paradigm - general principles

Tanguy Y. Seiwert et al.

NATURE CLINICAL PRACTICE ONCOLOGY (2007)

Add to Collection
Article Immunology

Potentiation of the immune response to non-adsorbed antigens by aluminum-containing adjuvants

Ilia Z. Romero Mendez et al.

VACCINE (2007)

Add to Collection
Article Allergy

Ultrafine but not fine particulate matter causes airway inflammation and allergic airway sensitization to co-administered antigen in mice

C. de Haar et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2006)

Add to Collection
Review Oncology

Photodynamic therapy and anti-tumour immunity

Ana P. Castano et al.

NATURE REVIEWS CANCER (2006)

Add to Collection
Article Medicine, General & Internal

Safety and immunogenicity of an inactivated subvirion influenza A (H5N1) vaccine

JJ Treanor et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Add to Collection
Article Immunology

Role of aluminum-containing adjuvants in antigen internalization by dendritic cells in vitro

GL Morefield et al.

VACCINE (2005)

Add to Collection
Article Biochemical Research Methods

Toxicity of gold nanoparticles functionalized with cationic and anionic side chains

CM Goodman et al.

BIOCONJUGATE CHEMISTRY (2004)

Add to Collection
Article Cell Biology

Aluminium compounds for use in vaccines

EB Lindblad

IMMUNOLOGY AND CELL BIOLOGY (2004)

Add to Collection
Article Immunology

Mechanisms of stimulation of the immune response by aluminum adjuvants

H HogenEsch

VACCINE (2002)

Add to Collection
Article Chemistry, Multidisciplinary

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

H Maeda et al.

JOURNAL OF CONTROLLED RELEASE (2000)

Add to Collection
Webinars Posters Questions Hubs Funding Journals Papers Connect Collections Reviewers About Us FAQs Mobile App Privacy Policy Terms of Use
© Peeref 2019-2024. All rights reserved.