Importance of long non-coding RNAs in the pathogenesis, diagnosis, and treatment of prostate cancer

Article Andrology

FOXD1-AS1 promotes malignant behaviours of prostate cancer cells via the miR-3167/YWHAZ axis

Weilong Qu et al.

Summary: FOXD1-AS1 promotes malignant phenotypes of prostate cancer cells by up-regulating YWHAZ through interacting with miR-3167. This mechanism provides potential prognostic biomarkers for pre-treatment evaluation in patients.

ANDROLOGIA (2022)

Add to Collection

Article Andrology

Differential gene expression of BCL-2, ZEB2-AS1 and BALR-2 in prostate cancer and benign prostatic hyperplasia

Maryam Ahani et al.

Summary: The study found that BCL-2 and BALR-2 have specific expression patterns in the progression of prostate cancer, which could be used as potential markers for distinguishing prostate cancer tissues from ANCTs or BPH samples.

ANDROLOGIA (2022)

Add to Collection

Article Oncology

Long Noncoding RNA Small Nucleolar RNA Host Gene 3 Mediates Prostate Cancer Migration, Invasion, and Epithelial-Mesenchymal Transition by Sponging miR-487a-3p to Regulate TRIM25

Lihang Yu et al.

Summary: SNHG3 mediates prostate cancer cell migration, invasion, and epithelial-mesenchymal transition by sponging miR-487a-3p to regulate TRIM25.

CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2022)

Add to Collection

Article Oncology

Cancer statistics, 2022

Rebecca L. Siegel et al.

Summary: Each year, the American Cancer Society compiles data on cancer occurrence and outcomes in the United States. The latest data shows that breast and prostate cancer progress has stagnated, while lung cancer has shown improvements in survival rates. Lung cancer incidence for advanced disease has declined while localized-stage rates have increased, resulting in higher survival rates. Mortality patterns align with incidence trends, with lung cancer deaths declining rapidly, breast cancer deaths slowing, and prostate cancer deaths stabilizing.

CA-A CANCER JOURNAL FOR CLINICIANS (2022)

Add to Collection

Article Oncology

Loss of Long Noncoding RNA NXTAR in Prostate Cancer Augments Androgen Receptor Expression and Enzalutamide Resistance

Ruchi Ghildiyal et al.

Summary: This study identifies a lncRNA called NXTAR that can epigenetically downregulate AR/AR-V7 expression, providing a therapeutic strategy to reinstate NXTAR expression for treating recurrent CRPC.

CANCER RESEARCH (2022)

Add to Collection

Article Biochemistry & Molecular Biology

SNHG3 could promote prostate cancer progression through reducing methionine dependence of PCa cells

Xiaotian Wang et al.

Summary: In recent years, the morbidity and mortality of prostate cancer have increased dramatically, while the understanding of its onset and progression remains limited. In this study, it was discovered that SNHG3 acts as a molecular sponge and stimulates proliferation, migration, and invasion of prostate cancer cells by targeting SLC7A11. It also inhibits methionine dependence and apoptosis and affects the cell cycle. These findings provide new insights into the molecular mechanism of SNHG3 in regulating prostate cancer progression.

CELLULAR & MOLECULAR BIOLOGY LETTERS (2022)

Add to Collection

Article Oncology

MiR-423-5p prevents MALAT1-mediated proliferation and metastasis in prostate cancer

Carmela Ferri et al.

Summary: This study found that MALAT1 expression is associated with high Gleason grade, metastasis occurrence, and reduced survival in PCa patients. The study also revealed a direct interaction between miR-423-5p and MALAT1, which inhibits MALAT1's activity and suppresses cell proliferation, migration, and invasion in PCa.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Silencing of TP73-AS1 impairs prostate cancer cell proliferation and induces apoptosis via regulation of TP73

Ahmet Arslan et al.

Summary: The study found that TP73-AS1 was upregulated and TP73 was downregulated in prostate cancer cells, with a negative correlation between them. Silencing TP73-AS1 gene induced cellular apoptosis, interfered with cell cycle progression, and modulated gene expression in prostate cancer cells, leading to reduced colony formation and migration capacities. The findings suggest a key regulatory role for the TP73-TP73-AS1 axis in prostate cancer development and progression, indicating a potential diagnostic and therapeutic target.

MOLECULAR BIOLOGY REPORTS (2022)

Add to Collection

Article Cell Biology

E2F transcription factor 2-activated DLEU2 contributes to prostate tumorigenesis by upregulating serum and glucocorticoid-induced protein kinase 1

Peizhang Li et al.

Summary: This study evaluated the expression and roles of lncRNA DLEU2 in prostate cancer and found that patients with high expression of DLEU2 had a poor prognosis. Overexpression of DLEU2 promoted the proliferation, migration, and invasion of prostate cancer. Mechanistically, DLEU2 acted as an miR-582-5p sponge to promote the expression of SGK1, and its transcription was activated by the dysregulation of E2F2 expression. Animal experiments confirmed that knockdown of DLEU2 attenuated prostate cancer tumorigenesis. These findings suggest that E2F2-activated DLEU2 may function as a competing endogenous RNA to facilitate prostate cancer progression.

CELL DEATH & DISEASE (2022)

Add to Collection

Article Oncology

LINC01207 promotes prostate cancer progression by sponging miR-1182 to upregulate AKT3

Daming Qin et al.

Summary: The study showed that LINC01207 was upregulated in prostate cancer tissues and played a promoting role in proliferation, migration, and invasion of PC cells, by sponging miR-1182 to regulate the protein levels of AKT3. Therefore, LINC01207 may play a role in tumorigenesis of PC and serve as a therapeutic target for PC treatment.

ONCOLOGY LETTERS (2022)

Add to Collection

Article Urology & Nephrology

PCGEM1 promotes proliferation, migration and invasion in prostate cancer by sponging miR-506 to upregulate TRIAP1

He Liu et al.

Summary: This study reveals the important role of a long noncoding RNA (PCGEM1) in prostate cancer. PCGEM1 upregulates TRIAP1 expression by interacting with miR-506-3p, thereby promoting proliferation, migration, and invasion of prostate cancer cells.

BMC UROLOGY (2022)

Add to Collection

Article Oncology

LncRNA EIF3J-AS1 functions as an oncogene by regulating MAFG to promote prostate cancer progression

Chen Ye et al.

Summary: This study demonstrates that EIF3J-AS1/MAFG may play a key role in facilitating the malignant progression of prostate cancer (PCa), and explores the mechanisms by which EIF3J-AS1 inhibits the proliferation and metastatic ability of PCa cells.

JOURNAL OF CANCER (2022)

Add to Collection

Article Oncology

Long non-coding RNA MAGI2-AS3 inactivates STAT3 pathway to inhibit prostate cancer cell proliferation via acting as a microRNA-424-5p sponge

Xin Wei et al.

Summary: This study revealed that MAGI2-AS3 acts as a negative regulator in prostate cancer development. Overexpression of MAGI2-AS3 leads to decreased cell viability and increased apoptosis in prostate cancer cells by inhibiting STAT3 pathway through modulating miR-424-5p and COP1 expression.

JOURNAL OF CANCER (2022)

Add to Collection

Article Biotechnology & Applied Microbiology

High expression of small nucleolar RNA host gene 3 predicts poor prognosis and promotes hone metastasis in prostate cancer by activating transforming growth factor-beta signaling

Xinhua Xi et al.

Summary: This study found that high expression of SNHG3 is associated with bone metastasis in prostate cancer, and can serve as a predictor of poor prognosis. SNHG3 enhances the transforming growth factor beta signaling pathway by targeting miR-214-3p, promoting tumor growth and bone metastasis.

BIOENGINEERED (2022)

Add to Collection

Article Oncology

The lncRNA NEAT1/miRNA-766-5p/E2F3 Regulatory Axis Promotes Prostate Cancer Progression

Wenhui Zhao et al.

Summary: NEAT1 facilitates prostate cancer progression by targeting the miR-766-5p/E2F3 axis. Silencing NEAT1 inhibits cell proliferation, invasion, and migration while promoting apoptosis and cell cycle arrest in prostate cancer cells. Mechanistic studies reveal that NEAT1 acts as a sponge for miR-766-5p, and upregulation of miR-766-5p inhibits prostate cancer progression.

JOURNAL OF ONCOLOGY (2022)

Add to Collection

Article Biochemistry & Molecular Biology

LINC00624/TEX10/NF-KB axis promotes proliferation and migration of human prostate cancer cells

Jian Zhou et al.

Summary: The study found that LINC00624 is highly expressed in prostate cancer and is associated with poor prognosis. Knockdown of LINC00624 was found to decrease the proliferative and migratory ability of prostate cancer cells. Mechanistically, LINC00624 and TEX10 co-regulate NF-KB activity.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022)

Add to Collection

Article Cardiac & Cardiovascular Systems

MIR22HG Aggravates Oxygen-Glucose Deprivation and Reoxygenation-Induced Cardiomyocyte Injury through the miR-9-3p/SH2B3 Axis

Yi Ge et al.

Summary: This study investigated the role and mechanism of MIR22HG in ischemia/reperfusion injury. The results showed that MIR22HG was upregulated in cardiomyocytes after ischemia/reperfusion treatment, and its knockdown promoted cell viability, inhibited apoptosis, and reduced extracellular matrix accumulation. Mechanistically, MIR22HG bound to miR-9-3p, which targeted the SH2B3 3' untranslated region, and MIR22HG positively regulated SH2B3 expression while miR-9-3p negatively regulated it.

CARDIOVASCULAR THERAPEUTICS (2022)

Add to Collection

Article Biotechnology & Applied Microbiology

lncRNA-DANCR Promotes Taxol Resistance of Prostate Cancer Cells through Modulating the miR-33b-5p-LDHA Axis

Yu-yong Wang et al.

Summary: This study reveals the role of DANCR in taxol resistance and the underlying molecular mechanisms. The study found that DANCR was upregulated and miR-33b-5p was downregulated in prostate tumor specimens and taxol-resistant prostate cancer cells. Silencing DANCR or overexpressing miR-33b-5p enhanced the taxol sensitivity of prostate cancer cells. The study also identified an association between DANCR and miR-33b-5p, leading to downregulation of miR-33b-5p in prostate cancer. The study further showed that glucose metabolism was elevated in taxol-resistant prostate cancer cells, and LDHA was a direct target of miR-33b-5p. Restoring miR-33b-5p successfully overcame the DANCR-promoted taxol resistance.

DISEASE MARKERS (2022)

Add to Collection

Article Endocrinology & Metabolism

Prognostic Value of Long Noncoding RNA SNHG11 in Patients with Prostate Cancer

Ying Li et al.

Summary: This study explores the prognostic value of long noncoding RNA SNHG11 in prostate cancer. The results show that SNHG11 is upregulated in prostate cancer and predicts an unfavorable prognosis. Knockdown of SNHG11 can suppress the proliferation, migration, and invasion of prostate cancer cells.

HORMONE AND METABOLIC RESEARCH (2022)

Add to Collection

Article Oncology

lncRNA MNX1-AS1 promotes prostate cancer progression through regulating miR-2113/MDM2 axis

Dong Liang et al.

Summary: The study found that MNX1-AS1 promotes prostate cancer progression by regulating the miR-2113/MDM2 axis.

MOLECULAR MEDICINE REPORTS (2022)

Add to Collection

Article Cell Biology

LncRNA-MALAT1 Regulates Cancer Glucose Metabolism in Prostate Cancer via MYBL2/mTOR Axis

Xiangyu Mu et al.

Summary: This study reveals that MALAT1 controls prostate cancer proliferation and glucose metabolism by upregulating the MYBL2-mTOR axis, and knocking down MALAT1 or MYBL2 significantly inhibits the proliferation capacity of PCa cell lines.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2022)

Add to Collection

Review Pathology

A review on the role of PCA3 lncRNA in carcinogenesis with an especial focus on prostate cancer

Soudeh Ghafouri-Fard et al.

Summary: PCA3 is a lncRNA with high specificity for prostate cancer and plays a crucial role in the pathogenesis of prostate cancer. It regulates multiple signaling pathways and is also expressed in other types of cancer cells. Several studies have evaluated the diagnostic value of PCA3 in prostate cancer and found that it has moderate diagnostic ability.

PATHOLOGY RESEARCH AND PRACTICE (2022)

Add to Collection

Article Cell Biology

RP1-59D14.5 triggers autophagy and represses tumorigenesis and progression of prostate cancer via activation of the Hippo signaling pathway

Bing Zhong et al.

Summary: RP1-59D14.5 acts as a tumor suppressor in prostate cancer (PCa) by activating the Hippo pathway through regulating the miR-147a/LATS1/2 and HUR/CK1/beta TrCP pathways, thus inhibiting the proliferation, migration, and invasion of PCa cells.

CELL DEATH & DISEASE (2022)

Add to Collection

Article Biotechnology & Applied Microbiology

Long non-coding RNA MIR22HG suppresses cell proliferation and promotes apoptosis in prostate cancer cells by sponging microRNA-9-3p

Wei Zhang et al.

Summary: This study found that long non-coding RNA MIR22HG is expressed at a low level in prostate cancer cells. MIR22HG overexpression inhibits cell proliferation and promotes apoptosis, possibly by sponging miR-9-3p. These findings are important for the treatment of prostate cancer.

BIOENGINEERED (2022)

Add to Collection

Article Oncology

LINC00893 inhibits the progression of prostate cancer through miR-3173-5p/SOCS3/JAK2/STAT3 pathway

Chuigong Yu et al.

Summary: This study demonstrated that LINC00893 suppresses the progression of prostate cancer cells through targeting the miR-3173-5p/SOCS3/JAK2/STAT3 signaling axis. This finding uncovers a novel tumor-suppressor role of LINC00893 in prostate cancer and suggests its potential as a targeted therapy strategy.

CANCER CELL INTERNATIONAL (2022)

Add to Collection

Article Oncology

METTL3-stabilized lncRNA SNHG7 accelerates glycolysis in prostate cancer via SRSF1/c-Myc axis

Jun Liu et al.

Summary: It has been discovered that METTL3-stabilized lncRNA SNHG7 accelerates glycolysis in prostate cancer via the SRSF1/c-Myc axis, which is significant for understanding the role of m(6)A in lncRNA metabolism and tumor progression.

EXPERIMENTAL CELL RESEARCH (2022)

Add to Collection

Article Oncology

Long non-coding RNA CASC11 interacts with YBX1 to promote prostate cancer progression by suppressing the p53 pathway

Xianchao Sun et al.

Summary: This study reveals the important role of long non-coding RNA CASC11 in the progression of prostate cancer. CASC11 promotes tumor proliferation and migration by promoting the cell cycle and competitively interacting with YBX1 to block the p53 pathway. The use of poly (beta-amino ester)/si-CASC11 nanoparticles enhances the antitumor effect by inhibiting CASC11 expression. This study provides a potential therapeutic strategy for the treatment of prostate cancer patients.

INTERNATIONAL JOURNAL OF ONCOLOGY (2022)

Add to Collection

Review Oncology

Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention

Sepideh Mirzaei et al.

Summary: This review highlights the role of epigenetic alterations in the development of prostate cancer, specifically focusing on lncRNAs. Aberrant expression of lncRNAs in prostate cancer is well-documented, affecting various molecular pathways and regulating tumor progression. Additionally, lncRNAs play a role in radio-resistance, chemo-resistance, and immune evasion of prostate cancer, making them potential targets for therapeutic interventions.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2022)

Add to Collection

Article Engineering, Biomedical

Effect and Mechanism of lncRNA CERS6-AS1 on the Biological Behavior of Prostate Cancer Cell

Fu Huang et al.

Summary: Silencing CERS6-AS1 can inhibit the proliferation and migration of prostate cancer cells DU145 and induce cell apoptosis, and the mechanism may be related to the regulation of the miR-16-5p/HMGA2 axis.

APPLIED BIONICS AND BIOMECHANICS (2022)

Add to Collection

Article Oncology

Long Non-Coding RNA AC008972.1 as a Novel Therapeutic Target for Prostate Cancer

Qingqi Zeng et al.

Summary: The study found that the high expression of lncRNA AC008972.1 in prostate cancer was associated with low overall survival in patients. Silencing of lncRNA AC008972.1 inhibited prostate cancer progression through multiple pathways, indicating its oncogenic role and potential as a novel therapeutic target for prostate cancer.

CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2022)

Add to Collection

Article Cell & Tissue Engineering

METTL3-Mediated m6A Modification of lncRNA MALAT1 Facilitates Prostate Cancer Growth by Activation of PI3K/AKT Signaling

Yuanshen Mao et al.

Summary: In prostate cancer, the m(6)A modification of MALAT1 mediated by METTL3 promotes the growth and invasion of tumor cells by activating the PI3K/AKT signaling pathway.

CELL TRANSPLANTATION (2022)

Add to Collection

Article Oncology

LncRNA NEAT1-associated aerobic glycolysis blunts tumor immunosurveillance by T cells in prostate cancer

Kai-Guo Xia et al.

Summary: In this study, the expression of NEAT1 was found to be higher in prostate cancer tissues compared to non-neoplastic tissues, and knockdown of NEAT1 significantly reduced the proliferative capability of PCa cells. Bioinformatics analysis showed enrichment of acidic substance-related gene sets associated with NEAT1 expression. Depletion of NEAT1 inhibited aerobic glycolysis in PCa cells and reduced lactate levels in the medium.

NEOPLASMA (2022)

Add to Collection

Article Environmental Sciences

DLX6-AS1accelerates cell proliferation through regulatingmiR-497-5p/SNCGpathway in prostate cancer

Xu Zhu et al.

Summary: This study found that DLX6-AS1 is significantly upregulated in prostate cancer and functions as an oncogene by promoting tumor growth through the miR-497-5p/SNCG axis. Silencing DLX6-AS1 can inhibit the progression of prostate cancer.

ENVIRONMENTAL TOXICOLOGY (2021)

Add to Collection

Article Biotechnology & Applied Microbiology

lncRNA PCAT14 Is a Diagnostic Marker for Prostate Cancer and Is Associated with Immune Cell Infiltration

Yunkun Yan et al.

Summary: The study revealed that PCAT14 is highly expressed in prostate cancer and may serve as a diagnostic marker. It is suggested that PCAT14 might promote the development of prostate cancer by regulating immune cell infiltration.

DISEASE MARKERS (2021)

Add to Collection

Article Biotechnology & Applied Microbiology

Long non-coding RNA SNHG8 promotes prostate cancer progression through repressing miR-384 and up-regulating HOXB7

Zhenfeng Shi et al.

Summary: In this study, SNHG8 was found to promote proliferation, migration and invasion of prostate cancer (PCa) cells through decoying miR-384 and up-regulating HOXB7.

JOURNAL OF GENE MEDICINE (2021)

Add to Collection

Article Medicine, Research & Experimental

PGM5-AS1 impairs miR-587-mediated GDF10 inhibition and abrogates progression of prostate cancer

Lei Du et al.

Summary: The study revealed that PGM5-AS1 upregulates GDF10 gene expression by competitively binding to miR-587, thus inhibiting proliferation and accelerating apoptosis of PCa cells.

JOURNAL OF TRANSLATIONAL MEDICINE (2021)

Add to Collection

Article Oncology

LINC00992 exerts oncogenic activities in prostate cancer via regulation of SOX4

Changde Fu et al.

Summary: The study revealed that LINC00992 (LNC992) is overexpressed in prostate cancer (PCa) and associated with poor prognosis. Knockdown of LNC992 inhibited proliferation, migration, and angiogenesis of PCa cells, while promoting SOX4 translation by binding to EIF4A3, and subsequently enhancing growth and metastasis of PCa cells.

EXPERIMENTAL CELL RESEARCH (2021)

Add to Collection

Article Oncology

Long non-coding RNA AC245100.4 promotes prostate cancer tumorigenesis via the microRNA-145-5p/RBBP5 axis

Hui Xie et al.

Summary: The study found that AC245100.4 expression was significantly upregulated in prostate cancer and its knockdown inhibited tumor growth. Functional analysis showed that AC245100.4 played a role in regulating cell proliferation and migration, while mechanistic studies revealed its interaction with miR-145-5p and RBBP5 through a ceRNA network.

ONCOLOGY REPORTS (2021)

Add to Collection

Article Cell Biology

Down-regulated LINC00115 inhibits prostate cancer cell proliferation and invasion via targeting miR-212-5p/FZD5/Wnt/beta-catenin axis

Naixiong Peng et al.

Summary: LINC00115 is significantly up-regulated in prostate cancer tissues and inhibits cell proliferation and invasion by targeting the miR-212-5p/FZD5/Wnt/β-catenin axis. This suggests that LINC00115 may be a potential therapeutic target for prostate cancer patients.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

Add to Collection

Article Medical Laboratory Technology

LncRNA FGF14-AS2 represses growth of prostate carcinoma cells via modulating miR-96-5p/AJAP1 axis

Rubing Li et al.

Summary: lncRNA FGF14-AS2 is a downregulated lncRNA in prostate carcinoma that can inhibit the expression of miR-96-5p, while miR-96-5p hampers AJAP1. The effects of FGF14-AS2 on prostate carcinoma cells' biological behaviors are mediated through modulation of miR-96-5p and its target gene AJAP1.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2021)

Add to Collection

Article Andrology

LncRNA SNHG9 is a prognostic biomarker and correlated with immune infiltrates in prostate cancer

Chao Li et al.

Summary: The study demonstrated that high expression of SNHG9 is associated with poor prognosis and immune infiltrations in prostate cancer, suggesting its potential as a promising prognostic biomarker in PCa.

TRANSLATIONAL ANDROLOGY AND UROLOGY (2021)

Add to Collection

Article Oncology

Long non-coding RNA SNHG16 functions as a tumor activator by sponging miR-373-3p to regulate the TGF-β-R2/SMAD pathway in prostate cancer

Wubin Weng et al.

Summary: This study revealed that SNHG16 promotes the proliferation and migration of prostate cancer cells by targeting the miR-373-3p/TGF-beta-R2/SMAD axis. The results indicate the potential role of SNHG16 as a therapeutic target in prostate cancer.

MOLECULAR MEDICINE REPORTS (2021)

Add to Collection

Article Biotechnology & Applied Microbiology

Long non-coding RNA ADAMTS9-AS1 inhibits the progression of prostate cancer by modulating the miR-142-5p/CCND1 axis

Zhien Zhou et al.

Summary: The study showed that ADAMTS9-AS1 is down-regulated in prostate cancer, and its overexpression can suppress cell proliferation and induce apoptosis. Furthermore, miR-142-5p mimic and si-CCND1 can weaken the inhibitory effects of ADAMTS9-AS1 overexpression on prostate cancer cell growth.

JOURNAL OF GENE MEDICINE (2021)

Add to Collection

Article Obstetrics & Gynecology

lncRNA HLA Complex Group 18 (HCG18) Facilitated Cell Proliferation, Invasion, and Migration of Prostate Cancer Through Modulating miR-370-3p/DDX3X Axis

Xiaobo Pan et al.

Summary: This study revealed the promoting effects of lncRNA HCG18 on cell proliferation, invasion, and migration in pancreatic cancer by up-regulating DDX3X through sponging miR-370-3p, providing a novel insight into the regulatory mechanisms of pancreatic cancer.

REPRODUCTIVE SCIENCES (2021)

Add to Collection

Article Cell Biology

LncRNA SNHG1 and RNA binding protein hnRNPL form a complex and coregulate CDH1 to boost the growth and metastasis of prostate cancer

Xiao Tan et al.

Summary: The interaction between LncRNA and RNA-binding protein (RBPs) is crucial in regulating tumor progression. SNHG1, a newly discovered lncRNA, competitively interacts with hnRNPL to inhibit E-cadherin translation, ultimately promoting metastasis in prostate cancer (PCa).

CELL DEATH & DISEASE (2021)

Add to Collection

Article Cell Biology

Exosomal long noncoding RNA HOXD-AS1 promotes prostate cancer metastasis via miR-361-5p/FOXM1 axis

Yongming Jiang et al.

Summary: Exosomal lncRNA HOXD-AS1 is upregulated in CRPC and metastatic PCa, promoting cancer cell metastasis by modulating the miR-361-5p/FOXM1 axis. Serum exosomal HOXD-AS1 is correlated with disease characteristics and survival outcomes, serving as a potential liquid biopsy biomarker for metastatic PCa detection and treatment guidance.

CELL DEATH & DISEASE (2021)

Add to Collection

Article Oncology

Long Non-Coding RNA (IncRNA) RAMS11 Promotes Metastatis and Cell Growth of Prostate Cancer by CBX4 Complex Binding to Top2α

Zhixiong Zheng et al.

Summary: The study revealed that lncRNA RAMS11 promotes cell growth and metastasis of prostate cancer by binding to CBX4 to activate Top2 alpha expression. This finding may offer a new approach for the treatment of prostate cancer.

CANCER MANAGEMENT AND RESEARCH (2021)

Add to Collection

Article Cell Biology

LncRNA PlncRNA-1 accelerates the progression of prostate cancer by regulating PTEN/Akt axis

Zilian Cui et al.

Aging-US (2021)

Add to Collection

Article Oncology

Long non-coding RNA LINC01116 acts as an oncogene in prostate cancer cells through regulation of miR-744-5p/UBE2L3 axis

Shengjie Yu et al.

Summary: Our study suggests that lncRNA LINC01116 acts as an oncogene in prostate cancer, promoting cell growth by regulating the miR-744-5p/UBE2L3 axis. Inhibition of LINC01116 could suppress cell proliferation, migration, invasion, and EMT progress in prostate cancer cells. Additionally, miR-744-5p was found to bind with LINC01116, while UBE2L3 was validated as the target gene of miR-744-5p.

CANCER CELL INTERNATIONAL (2021)

Add to Collection

Article Medicine, Research & Experimental

Knockdown of lncRNA MIR4435-2HG and ST8SIA1 expression inhibits the proliferation, invasion and migration of prostate cancer cells in vitro and in vivo by blocking the activation of the FAK/AKT/β-catenin signaling pathway

Pengyi Xing et al.

Summary: The study demonstrated that interference with MIR4435-2HG and ST8SIA1 could effectively inhibit the proliferation, invasion, and migration of prostate cancer cells by blocking the activation of the FAK/AKT/beta-catenin signaling pathway.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2021)

Add to Collection

Review Cell Biology

Interaction between Non-Coding RNAs and Androgen Receptor with an Especial Focus on Prostate Cancer

Mohammad Taheri et al.

Summary: The androgen receptor (AR) has multiple functional domains that can affect the pathogenesis of human malignancies, especially prostate cancer, through genomic and non-genomic activities. The interactions between non-coding RNAs and AR play a crucial role in designing novel treatment options and modulating response to conventional therapeutics.

CELLS (2021)

Add to Collection

Article Oncology

Long non-coding RNA NORAD promotes the prostate cancer cell extracellular vesicle release via microRNA-541-3p-regulated PKM2 to induce bone metastasis of prostate cancer

Chuan-yi Hu et al.

Summary: This study found that NORAD is highly expressed in PCa tissues and cell lines, and NORAD knockdown can reduce EVs secretion and internalization, inhibit proliferation, migration, and bone metastasis of PCa cells. Additionally, NORAD interacts with miR-541-3p, leading to upregulation of PKM2, which further promotes the transfer of PKH67-labeled EVs to bone marrow stromal cells.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)

Add to Collection

Article Biotechnology & Applied Microbiology

Long non-coding DANCR targets miR-185-5p to upregulate LIM and SH3 protein 1 promoting prostate cancer via the FAK/PI3K/AKT/GSK3β/snail pathway

Wendong Sun et al.

Summary: The study revealed that DANCR in prostate cancer activates the FAK/PI3K/AKT/GSK3 beta/Snail pathway through the miR-185-5p/LASP1 axis, promoting malignancy. It could serve as a potential biomarker for the diagnosis and monitoring of prostate cancer.

JOURNAL OF GENE MEDICINE (2021)

Add to Collection

Article Cell Biology

SNHG10 Is a Prognostic Biomarker Correlated With Immune Infiltrates in Prostate Cancer

Qiang Chen et al.

Summary: The study revealed that SNHG10 is overexpressed in prostate cancer and is associated with advanced clinical parameters, showing significant diagnostic ability. SNHG10 expression is also correlated with oxidative phosphorylation and immune infiltrated cells, affecting cell proliferation, migration, and invasion of PC.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Add to Collection

Article Cell Biology

Long Non-coding RNAs LINC01679 as a Competitive Endogenous RNAs Inhibits the Development and Progression of Prostate Cancer via Regulating the miR-3150a-3p/SLC17A9 Axis

Yuan-yuan Mi et al.

Summary: This study focused on selecting potential lncRNA signatures related to prostate cancer for prognosis prediction accuracy. Through bioinformatics analysis, it was revealed that LINC01679 regulates the miR-3150a-3p/SLC17A9 axis, playing a crucial role in suppressing PCa development.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Add to Collection

Article Andrology

Role of BCAR4 in prostate cancer cell autophagy

Zhiping Cai et al.

Summary: The study found that BCAR4 and Beclin-1 are both upregulated in prostate cancer and positively correlated. BCAR4 enhances autophagy in PC cells by activating Beclin-1, while Beclin-1 does not control levels of BCAR4. The regulatory relationship between BCAR4 and Beclin-1 is mediated by miR-15 and miR-146.

TRANSLATIONAL ANDROLOGY AND UROLOGY (2021)

Add to Collection

Review Pathology

BCYRN1: An oncogenic lncRNA in diverse cancers

Soudeh Ghafouri-Fard et al.

Summary: BCYRN1, a long noncoding RNA primarily found in neurons, not only plays a role in the pathogenesis of neurodegenerative disorders, but also in the process of carcinogenesis. Studies have shown elevated levels of BCYRN1 in various cancer types are associated with poor patient survival, making it a potential candidate for targeted therapy in the field of cancer.

PATHOLOGY RESEARCH AND PRACTICE (2021)

Add to Collection

Article Oncology

CASC11 promotes aggressiveness of prostate cancer cells through miR-145/IGF1R axis

Ozel Capik et al.

Summary: This study investigated the potential functions of CASC11 in prostate cancer progression. The results showed that upregulation of CASC11 promotes cellular phenotypes associated with prostate cancer progression through the CASC11/miR-145/IGF1R axis.

PROSTATE CANCER AND PROSTATIC DISEASES (2021)

Add to Collection

Article Oncology

Long non-coding RNA SNHG17 enhances the aggressiveness of C4-2 human prostate cancer cells in association with β-catenin signaling

Haijun Zhao et al.

Summary: The study demonstrated that the high expression of lncRNA SNHG17 in prostate cancer is associated with poor patient outcomes, suggesting its potential as a therapeutic target for PCa.

ONCOLOGY LETTERS (2021)

Add to Collection

Article Oncology

LINC00467 Promotes Prostate Cancer Progression via M2 Macrophage Polarization and the miR-494-3p/STAT3 Axis

Hao Jiang et al.

Summary: The study revealed that LINC00467 was upregulated in prostate cancer, and its inhibition suppressed the growth, migration, and invasion of PC cells, leading to a suppression of tumor growth. Furthermore, LINC00467 was primarily localized in the cytoplasm, promoting prostate cancer progression through the miR-494-3p/STAT3 axis.

FRONTIERS IN ONCOLOGY (2021)

Add to Collection

Article Oncology

Glioma glycolipid metabolism: MSI2-SNORD12B-FIP1L1-ZBTB4 feedback loop as a potential treatment target

Weiwei Dong et al.

Summary: Increased expression of MSI2 and SNORD12B and decreased expression of ZBTB4 were observed in GBM tissues and cells. Inhibiting MSI2 or SNORD12B, or overexpressing ZBTB4, suppressed glycolipid metabolism and proliferation of GBM cells. These findings suggest a potential therapeutic target for glioma treatment through a positive feedback loop involving MSI2/SNORD12B/FIP1L1/ZBTB4.

CLINICAL AND TRANSLATIONAL MEDICINE (2021)

Add to Collection

Article Biology

Long Noncoding RNA NEAT1 as a Potential Candidate Biomarker for Prostate Cancer

Diana Nitusca et al.

Summary: This study suggests that NEAT1 could serve as a diagnostic biomarker for PCa with a relatively high diagnostic value. Further studies on larger cohorts are needed to confirm these findings and explore the oncogenic mechanism of NEAT1 in the development of PCa.

LIFE-BASEL (2021)

Add to Collection

Article Cell Biology

LncRNA CCAT1 promotes prostate cancer cells proliferation, migration, and invasion through regulation of miR-490-3p/FRAT1 axis

Xiaowei Cai et al.

Aging-US (2021)

Add to Collection

Article Oncology

AGAP2-AS1/miR-628-5p/FOXP2 feedback loop facilitates the growth of prostate cancer via activating WNT pathway

Xu Zhao et al.

Summary: AGAP2-AS1, acting as an oncogene in some cancers like prostate cancer, is highly expressed in PCa cells and promotes cell growth by sponging miR-628-5p and regulating the expression of FOXP2. The feedback loop among AGAP2-AS1, miR-628-5p, and FOXP2 facilitates PCa cell growth by activating the WNT pathway.

CARCINOGENESIS (2021)

Add to Collection

Article Medicine, Research & Experimental

lncRNA SNHG11 facilitates prostate cancer progression through the upregulation of IGF-1R expression and by sponging miR-184

Qiang Xie et al.

Summary: The study found that SNHG11 is upregulated in prostate cancer and enhances PCa progression by modulating the miR-184/IGF-1R signaling axis.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2021)

Add to Collection

Article Oncology

A Novel Urine Exosomal lncRNA Assay to Improve the Detection of Prostate Cancer at Initial Biopsy: A Retrospective Multicenter Diagnostic Feasibility Study

Yun Li et al.

Summary: This study developed and validated a novel noninvasive post-DRE urine-based lncRNA assay for the diagnosis of prostate cancer (PCa) and clinically significant PCa. The assay demonstrated good diagnostic power and clinical utility, improving early diagnosis of PCa and high-grade PCa.

CANCERS (2021)

Add to Collection

Review Cell Biology

Role of lncRNA BANCR in Human Cancers: An Updated Review

Bashdar Mahmud Hussen et al.

Summary: BANCR, a long non-coding RNA located in a gene desert region on chromosome 9, has been shown to play a role in tumorigenesis by affecting cell proliferation, migration, and various other processes. It has different expression patterns in various cancers, with up-regulation in some cancers and down-regulation in others. More research is needed to fully understand its specific mechanisms in different types of cancer.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Add to Collection

Article Medicine, General & Internal

Associations between LncRNA MALAT1 Polymorphisms and Lymph Node Metastasis in Prostate Cancer

Ju-Chuan Hu et al.

Summary: Evidence suggests that certain SNPs of MALAT1 are significantly associated with the susceptibility to advanced Gleason grade and nodal metastasis in prostate cancer, indicating an enhanced oncogenic potential in the presence of these SNPs.

DIAGNOSTICS (2021)

Add to Collection

Article Andrology

Long ncRNA MALAT1 promotes cell proliferation, migration, and invasion in prostate cancer via sponging miR-145

Dingrong Zhang et al.

Summary: The study reveals that MALAT1 acts as a competing endogenous RNA (ceRNA) to regulate miR-145, playing a significant role in the progression of prostate cancer.

TRANSLATIONAL ANDROLOGY AND UROLOGY (2021)

Add to Collection

Article Oncology

m6A modification of lncRNA PCAT6 promotes bone metastasis in prostate cancer through IGF2BP2-mediated IGF1R mRNA stabilization

Chuandong Lang et al.

Summary: This study uncovers a novel molecular mechanism involving the m(6)A-induced PCAT6/IGF2BP2/IGF1R axis in promoting PCa bone metastasis and tumor growth, suggesting that PCAT6 may serve as a promising prognostic marker and therapeutic target for bone-metastatic PCa.

CLINICAL AND TRANSLATIONAL MEDICINE (2021)

Add to Collection

Article Oncology

PVT1 Expression Is a Predictor for Poor Survival of Prostate Cancer Patients

Jianhua Liu et al.

Summary: The study investigated the expression of PVT1 in prostate cancer and found significant correlations with tumor-related characteristics, suggesting that PVT1 may serve as a biomarker for the diagnosis and prognosis of prostate cancer.

TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2021)

Add to Collection

Article Biotechnology & Applied Microbiology

Muscleblind-like 1 antisense RNA 1 inhibits cell proliferation, invasion, and migration of prostate cancer by sponging miR-181a-5p and regulating PTEN/PI3K/AKT/mTOR signaling

Xiang Ding et al.

Summary: The study found that MBNL1-AS1 inhibits the progression of Prostate cancer by regulating miR-181a-5p and the PTEN/PI3K/AKT/mTOR signaling pathway.

BIOENGINEERED (2021)

Add to Collection

Article Oncology

LncRNA BLACAT1 Promotes Proliferation, Migration and Invasion of Prostate Cancer Cells via Regulating miR-29a-3p/DVL3 Axis

Bo Liao et al.

Summary: BLACAT1 is significantly up-regulated in prostate cancer tissues, modulating the proliferative and metastatic abilities of prostate cancer cells and potentially regulating the expression of DVL3 by sponging miR-29a-3p.

TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2021)

Add to Collection

Article Oncology

Overexpression of LINC00852 promotes prostate cancer cell proliferation and metastasis

Shengming Yi et al.

Summary: In this study, it was found that LINC00852 is highly expressed in prostate cancer tissues. Overexpression of LINC00852 significantly enhanced proliferation and colony formation abilities of PC3 prostate cancer cells, as well as migration and invasion capabilities. Flow cytometric analysis showed a decrease in G0/G1 phase cells, and the expression of epithelial-mesenchymal transition-related proteins was affected by overexpression of LINC00852.

ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2021)

Add to Collection

Article Medicine, Research & Experimental

LncRNA DANCR silence inhibits SOX5-medicated progression and autophagy in osteosarcoma via regulating miR-216a-5p

Zhengxia Pan et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Add to Collection

Article Medicine, Research & Experimental

MALAT1 knockdown inhibits prostate cancer progression by regulating miR-140/BIRC6 axis

Tongtong Hao et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Add to Collection

Article Oncology

Knockdown of lncRNA CCAT1 enhances sensitivity of paclitaxel in prostate cancer via regulating miR-24-3p and FSCN1

Xiaohui Li et al.

CANCER BIOLOGY & THERAPY (2020)

Add to Collection

Article Oncology

Long Noncoding RNA SNHG1 Contributes to the Promotion of Prostate Cancer Cells Through Regulating miR-377-3p/AKT2 Axis

Mao Xie et al.

CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2020)

Add to Collection

Article Oncology

LINC00908 negatively regulates microRNA-483-5p to increase TSPYL5 expression and inhibit the development of prostate cancer

Li Fan et al.

CANCER CELL INTERNATIONAL (2020)

Add to Collection

Article Oncology

Long non-coding RNA FER1L4 inhibits prostate cancer progression via sponging miR-92a-3p and upregulation of FBXW7

Wei Huo et al.

CANCER CELL INTERNATIONAL (2020)

Add to Collection

Article Physiology

Long non-coding RNA PRRT3-AS1 silencing inhibits prostate cancer cell proliferation and promotes apoptosis and autophagy

Fan Li et al.

EXPERIMENTAL PHYSIOLOGY (2020)

Add to Collection

Article Cell Biology

Long non-coding RNA LINC00673 silencing inhibits proliferation and drug resistance of prostate cancer cells via decreasing KLF4 promoter methylation

Zhenming Jiang et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)

Add to Collection

Article Medicine, General & Internal

Long non-coding RNA small nucleolar RNA host gene 7 expression level in prostate cancer tissues predicts the prognosis of patients with prostate cancer

Qier Xia et al.

MEDICINE (2020)

Add to Collection

Article Cell Biology

The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles

Andrew M. Leidal et al.

NATURE CELL BIOLOGY (2020)

Add to Collection

Article Biotechnology & Applied Microbiology

Long Non Coding RNA SNHG16 Facilitates Proliferation, Migration, Invasion and Autophagy of Neuroblastoma Cells via Sponging miR-542-3p and Upregulating ATG5 Expression

Yi Wen et al.

ONCOTARGETS AND THERAPY (2020)

Add to Collection

Article Pharmacology & Pharmacy

Curcumol enhances the sensitivity of doxorubicin in triple-negative breast cancer via regulating the miR-181b-2-3p-ABCC3 axis

Cheng Zeng et al.

BIOCHEMICAL PHARMACOLOGY (2020)

Add to Collection

Article Biochemistry & Molecular Biology

The long non-coding RNA LINC00473 contributes to cell proliferation via JAK-STAT3 signaling pathway by regulating miR-195-5p/SEPT2 axis in prostate cancer

Zengshu Xing et al.

BIOSCIENCE REPORTS (2020)

Add to Collection

Article Oncology

Downregulation of lncRNA ZEB1-AS1 Represses Cell Proliferation, Migration, and Invasion Through Mediating PI3K/AKT/mTOR Signaling by miR-342-3p/CUL4B Axis in Prostate Cancer

Teng Ma et al.

CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2020)

Add to Collection

Article Oncology

Long Noncoding RNA SOX2-OT Knockdown Inhibits Proliferation and Metastasis of Prostate Cancer Cells Through Modulating miR-452-5p/HMGB3 Axis and Inactivating Wnt/β-Catenin Pathway

Xiaofei Song et al.

CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2020)

Add to Collection

Article Biochemistry & Molecular Biology

Long non-coding RNA FAM66C is associated with clinical progression and promotes cell proliferation by inhibiting proteasome pathway in prostate cancer

Yimin Xie et al.

CELL BIOCHEMISTRY AND FUNCTION (2020)

Add to Collection

Article Biochemistry & Molecular Biology

Long non-coding RNA LINC00337 induces autophagy and chemoresistance to cisplatin in esophageal squamous cell carcinoma cells via upregulation of TPX2 by recruiting E2F4

Chengliang Yang et al.

FASEB JOURNAL (2020)

Add to Collection

Article Cell Biology

Long intergenic noncoding RNA 00844 promotes apoptosis and represses proliferation of prostate cancer cells through upregulating GSTP1 by recruiting EBF1

Qiu Kaiyan et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2020)

Add to Collection

Article Oncology

lncRNA ZFAS1 Is Involved in the Proliferation, Invasion and Metastasis of Prostate Cancer Cells Through Competitively Binding to miR-135a-5p

Jiaqiang Pan et al.

CANCER MANAGEMENT AND RESEARCH (2020)

Add to Collection

Article Biotechnology & Applied Microbiology

Knockdown of lncRNA TUG1 Enhances Radiosensitivity of Prostate Cancer via the TUG1/miR-139-5p/SMC1A Axis

Dianhui Xiu et al.

ONCOTARGETS AND THERAPY (2020)

Add to Collection

Article Biotechnology & Applied Microbiology

LncRNA LINC00665 Promotes Prostate Cancer Progression via miR-1224-5p/SNDI Axis

Wei Chen et al.

ONCOTARGETS AND THERAPY (2020)

Add to Collection

Article Cell Biology

LncRNA SNHG17 aggravated prostate cancer progression through regulating its homolog SNORA71B via a positive feedback loop

Gaoliang Wu et al.

CELL DEATH & DISEASE (2020)

Add to Collection

Article Oncology

lncRNA Erbb4-IR is downregulated in prostate carcinoma and predicts prognosis

Jiuyun Zhou et al.

ONCOLOGY LETTERS (2020)

Add to Collection

Article Oncology

LncRNA SNHG3 sponges miR-577 to up-regulate SMURF1 expression in prostate cancer

Teng Li et al.

CANCER MEDICINE (2020)

Add to Collection

Article Medicine, General & Internal

Role of long non-coding RNA NEAT1 in the prognosis of prostate cancer patients

Junchao Bai et al.

MEDICINE (2020)

Add to Collection

Article Oncology

LncRNA-SNHG16 Silencing Inhibits Prostate Carcinoma Cell Growth, Downregulate GLUT1 Expression and Reduce Glucose Uptake

Mingfeng Shao et al.

CANCER MANAGEMENT AND RESEARCH (2020)

Add to Collection

Article Genetics & Heredity

Long Non-coding RNA SNHG17 Promotes Cell Proliferation and Invasion in Castration-Resistant Prostate Cancer by Targeting the miR-144/CD51 Axis

Minghua Bai et al.

FRONTIERS IN GENETICS (2020)

Add to Collection

Article Oncology

TUG1 knockdown inhibits the tumorigenesis and progression of prostate cancer by regulating microRNA-496/Wnt/β-catenin pathway

Gang Li et al.

ANTI-CANCER DRUGS (2020)

Add to Collection

Article Oncology

LINC00689 promotes prostate cancer progression via regulating miR-496/CTNNB1 to activate Wnt pathway

Liwei Meng et al.

CANCER CELL INTERNATIONAL (2020)

Add to Collection

Article Oncology

MCM3AP-AS1/miR-876-5p/WNT5A axis regulates the proliferation of prostate cancer cells

Jie Wu et al.

CANCER CELL INTERNATIONAL (2020)

Add to Collection

Article Oncology

Long non-coding RNA SNHG6 regulates the sensitivity of prostate cancer cells to paclitaxel by sponging miR-186

Chunhui Cao et al.

CANCER CELL INTERNATIONAL (2020)

Add to Collection

Article Biology

Identification of long non-coding RNAs in advanced prostate cancer associated with androgen receptor splicing factors

Ken-ichi Takayama et al.

COMMUNICATIONS BIOLOGY (2020)

Add to Collection

Article Oncology

The ERG-Regulated LINC00920 Promotes Prostate Cancer Cell Survival via the 14-3-3ε-FOXO Pathway

Arlou Kristina Angeles et al.

MOLECULAR CANCER RESEARCH (2020)

Add to Collection

Article Oncology

NNT-AS1 modulates prostate cancer cell proliferation, apoptosis and migration through miR-496/DDIT4 axis

Changlei Yao et al.

CANCER CELL INTERNATIONAL (2020)

Add to Collection

Article Oncology

LncRNA KCNQ1OT1 sponges miR-15a to promote immune evasion and malignant progression of prostate cancer via up-regulating PD-L1

Qi-Hua Chen et al.

CANCER CELL INTERNATIONAL (2020)

Add to Collection

Article Oncology

Long noncoding RNA LINC00261 suppresses prostate cancer tumorigenesis through upregulation of GATA6-mediated DKK3

Yang Li et al.

CANCER CELL INTERNATIONAL (2020)

Add to Collection

Article Biotechnology & Applied Microbiology

Long Noncoding RNA PVT1 Promotes Prostate Cancer Metastasis by Increasing NOP2 Expression via Targeting Tumor Suppressor MicroRNAs

Feng Sun et al.

ONCOTARGETS AND THERAPY (2020)

Add to Collection

Article Biotechnology & Applied Microbiology

The Long Non-Coding RNA IDH1-AS1 Promotes Prostate Cancer Progression by Enhancing IDH1 Enzyme Activity

Shuo Wu et al.

ONCOTARGETS AND THERAPY (2020)

Add to Collection

Article Genetics & Heredity

LncRNA HORAS5 promotes taxane resistance in castration-resistant prostate cancer via a BCL2A1-dependent mechanism

Perla Pucci et al.

EPIGENOMICS (2020)

Add to Collection

Article Medicine, General & Internal

Association of long-chain non-coding RNAGAS5gene polymorphisms with prostate cancer risk and prognosis in Chinese Han population

Lisha Zhao et al.

MEDICINE (2020)

Add to Collection

Article Genetics & Heredity

LncRNA AC245100.4binds HSP90 to promote the proliferation of prostate cancer

Rongjun Cui et al.

EPIGENOMICS (2020)

Add to Collection

Article Oncology

Long Non-Coding RNA GAS5 Suppresses Tumor Progression and Enhances the Radiosensitivity of Prostate Cancer Through the miR-320a/RAB21 Axis

Xiulong Ma et al.

CANCER MANAGEMENT AND RESEARCH (2020)

Add to Collection

Article Oncology

Long non-coding RNA NORAD contributes to the proliferation, invasion and EMT progression of prostate cancer via the miR-30a-5p/RAB11A/WNT/β-catenin pathway

Yunxia Zhang et al.

CANCER CELL INTERNATIONAL (2020)

Add to Collection

Article Biochemistry & Molecular Biology

Long non-coding RNA NEAT1 promotes bone metastasis of prostate cancer through N6-methyladenosine

Simeng Wen et al.

MOLECULAR CANCER (2020)

Add to Collection

Article Biotechnology & Applied Microbiology

Long Noncoding RNA SNHG12 Promotes Prostate Tumor Occurrence and Progression via AKT Regulation

Zheng Chen et al.

BIOMED RESEARCH INTERNATIONAL (2020)

Add to Collection

Article Pathology

High expression of lncRNA SNHG1 in prostate cancer patients and inhibition of SNHG1 suppresses cell proliferation and promotes apoptosis

Qi Tang et al.

INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY (2020)

Add to Collection

Article Oncology

LncRNA AFAP1-AS1 modulates the sensitivity of paclitaxel-resistant prostate cancer cells to paclitaxel via miR-195-5p/FKBP1A axis

Weiping Leng et al.

CANCER BIOLOGY & THERAPY (2020)

Add to Collection

Article Mathematical & Computational Biology

Long noncoding RNA MIR22HG is down-regulated in prostate cancer

Hao Shen et al.

MATHEMATICAL BIOSCIENCES AND ENGINEERING (2020)

Add to Collection

Article Oncology

Altered expression of lncRNA NCK1-AS1 distinguished patients with prostate cancer from those with benign prostatic hyperplasia

Zhihui Guan et al.

ONCOLOGY LETTERS (2019)

Add to Collection

Article Oncology

IncRNA DGCR5 Up-Regulates TGF-β1, Increases Cancer Cell Stemness and Predicts Survival of Prostate Cancer Patients

Bin Li et al.

CANCER MANAGEMENT AND RESEARCH (2019)

Add to Collection

Article Medicine, General & Internal

Impact of GAS5 genetic polymorphism on prostate cancer susceptibility and clinicopathologic characteristics

Chia-Yen Lin et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2019)

Add to Collection

Article Genetics & Heredity

Analysis of the androgen receptor-regulated lncRNA landscape identifies a role for ARLNC1 in prostate cancer progression

Yajia Zhang et al.

NATURE GENETICS (2018)

Add to Collection

Review Cell Biology

Genetics and biology of prostate cancer

Guocan Wang et al.

GENES & DEVELOPMENT (2018)

Add to Collection

Article Oncology

Long non-coding RNA urothelial carcinoma associated 1 ( UCA1) mediates radiation response in prostate cancer

Alireza Fotouhi Ghiam et al.

ONCOTARGET (2017)

Add to Collection

Article Genetics & Heredity

HOTAIR genetic variants are associated with prostate cancer and benign prostate hyperplasia in an Iranian population

Mohammad Taheri et al.

GENE (2017)

Add to Collection

Review Oncology

Long non-coding RNAs and prostate cancer

Aya Misawa et al.

CANCER SCIENCE (2017)

Add to Collection

Article Medicine, Research & Experimental

Association of ANRIL gene polymorphisms with prostate cancer and benign prostatic hyperplasia in an Iranian population

Mohammad Taheri et al.

BIOMARKERS IN MEDICINE (2017)

Add to Collection

Article Pathology

The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma Definition of Grading Patterns and Proposal for a New Grading System

Jonathan I. Epstein et al.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2016)

Add to Collection

Article Biochemistry & Molecular Biology

Androgen-induced Long Noncoding RNA (lncRNA) SOCS2-AS1 Promotes Cell Growth and Inhibits Apoptosis in Prostate Cancer Cells

Aya Misawa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Add to Collection

Article Cell Biology

LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer

Ali Zhang et al.

CELL REPORTS (2015)

Add to Collection

Article Multidisciplinary Sciences

The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer

Dimple Chakravarty et al.

NATURE COMMUNICATIONS (2014)

Add to Collection

Article Oncology

The Long Non-Coding RNA PCAT-1 Promotes Prostate Cancer Cell Proliferation through cMyc

John R. Prensner et al.

NEOPLASIA (2014)

Add to Collection

Article Biochemistry & Molecular Biology

Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer

Ken-ichi Takayama et al.

EMBO JOURNAL (2013)

Add to Collection

Article Multidisciplinary Sciences

lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs

Liuqing Yang et al.

NATURE (2013)

Add to Collection

Article Genetics & Heredity

The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex

John R. Prensner et al.

NATURE GENETICS (2013)

Add to Collection

Review Oncology

The Emergence of lncRNAs in Cancer Biology

John R. Prensner et al.

CANCER DISCOVERY (2011)

Add to Collection

Article Public, Environmental & Occupational Health

Smoking as a Risk Factor for Prostate Cancer: A Meta-Analysis of 24 Prospective Cohort Studies

Michael Huncharek et al.

AMERICAN JOURNAL OF PUBLIC HEALTH (2010)

Add to Collection

Article Medical Laboratory Technology

APTIMA PCA3 molecular urine test: Development of a method to aid in the diagnosis of prostate cancer

Jack Groskopf et al.

CLINICAL CHEMISTRY (2006)

Add to Collection

Importance of long non-coding RNAs in the pathogenesis, diagnosis, and treatment of prostate cancer

Related references

Export Citation

Share Paper