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ONCOLOGY REPORTS (2016)
NON-CODING RNAs IN DEVELOPMENT AND DISEASE: BACKGROUND, MECHANISMS, AND THERAPEUTIC APPROACHES
Julia Beermann et al.
PHYSIOLOGICAL REVIEWS (2016)
MiR-100 Inhibits Osteosarcoma Cell Proliferation, Migration, and Invasion and Enhances Chemosensitivity by Targeting IGFIR
Yang Liu et al.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2016)
MicroRNA-21 promotes proliferation, invasion and suppresses apoptosis in human osteosarcoma line MG63 through PTEN/Akt pathway
Chen Lv et al.
TUMOR BIOLOGY (2016)
Increased expression of microRNA-148a in osteosarcoma promotes cancer cell growth by targeting PTEN
Hao Zhang et al.
ONCOLOGY LETTERS (2016)
Overcoming Therapeutic Resistance of Bone Sarcomas: Overview of the Molecular Mechanisms and Therapeutic Targets for Bone Sarcoma Stem Cells
Tomohiro Fujiwara et al.
STEM CELLS INTERNATIONAL (2016)
The Warburg effect in tumor progression: Mitochondrial oxidative metabolism as an anti-metastasis mechanism
Jianrong Lu et al.
CANCER LETTERS (2015)
The Down-Regulation of MicroRNA-497 Contributes to Cell Growth and Cisplatin Resistance Through PI3K/Akt Pathway in Osteosarcoma
Xue-jun Shao et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)
The PI3K/AKT/mTOR pathway as a therapeutic target in ovarian cancer
Seiji Mabuchi et al.
GYNECOLOGIC ONCOLOGY (2015)
Osteosarcoma: Current Treatment and a Collaborative Pathway to Success
Michael S. Isakoff et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
microRNA-93 promotes cell proliferation via targeting of PTEN in Osteosarcoma cells
Masanori Kawano et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2015)
miR-214 promotes osteosarcoma tumor growth and metastasis by decreasing the expression of PTEN
Chun-Jie Liu et al.
MOLECULAR MEDICINE REPORTS (2015)
GPNMB cooperates with neuropilin-1 to promote mammary tumor growth and engages integrin α5β1 for efficient breast cancer metastasis
G. Maric et al.
ONCOGENE (2015)
MicroRNA-1908 is upregulated in human osteosarcoma and regulates cell proliferation and migration by repressing PTEN expression
Hongmou Yuan et al.
ONCOLOGY REPORTS (2015)
MicroRNA-375 functions as a tumor suppressor in osteosarcoma by targeting PIK3CA
Zhi-cai Shi et al.
TUMOR BIOLOGY (2015)
VEGF-mediated suppression of cell proliferation and invasion by miR-410 in osteosarcoma
Dong Zhao et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2015)
Less understood issues: p21Cip1 in mitosis and its therapeutic potential
N-N Kreis et al.
ONCOGENE (2015)
MicroRNA-26a inhibits osteosarcoma cell proliferation by targeting IGF-1
Xinyu Tan et al.
BONE RESEARCH (2015)
PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance
Merritt P. Edlind et al.
ASIAN JOURNAL OF ANDROLOGY (2014)
miR-17 inhibitor suppressed osteosarcoma tumor growth and metastasis via increasing PTEN expression
Yong Gao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Kinome and mRNA expression profiling of high-grade osteosarcoma cell lines implies Akt signaling as possible target for therapy
Marieke L. Kuijjer et al.
BMC MEDICAL GENOMICS (2014)
Osteosarcoma treatment - Where do we stand? A state of the art review
Anja Luetke et al.
CANCER TREATMENT REVIEWS (2014)
MicroRNA-141 and MicroRNA-146b-5p Inhibit the Prometastatic Mesenchymal Characteristics through the RNA-binding Protein AUF1 Targeting the Transcription Factor ZEB1 and the Protein Kinase AKT
Huda H. Al-Khalaf et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Metastatic potential in MDA-MB-231 human breast cancer cells is inhibited by proton beam irradiation via the Akt/nuclear factor-κB signaling pathway
Kyu-Shik Lee et al.
MOLECULAR MEDICINE REPORTS (2014)
MicroRNA-214 regulates osteosarcoma survival and growth by directly targeting phosphatase and tensin homolog
Xuming Wang et al.
MOLECULAR MEDICINE REPORTS (2014)
microRNA-25 promotes osteosarcoma cell proliferation by targeting the cell-cycle inhibitor p27
Xiu-Hui Wang et al.
MOLECULAR MEDICINE REPORTS (2014)
Inhibition of the PI3K/Akt/mTOR Signaling Pathway in Diffuse Large B-Cell Lymphoma: Current Knowledge and Clinical Significance
Agata Majchrzak et al.
MOLECULES (2014)
Discovery and saturation analysis of cancer genes across 21 tumour types
Michael S. Lawrence et al.
NATURE (2014)
PI3K and cancer: lessons, challenges and opportunities
David A. Fruman et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
MicroRNA-1 functions as a potential tumor suppressor in osteosarcoma by targeting Med1 and Med31
Chaoyin Jiang et al.
ONCOLOGY REPORTS (2014)
miR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma
Fei Guo et al.
ONCOLOGY REPORTS (2014)
The mTOR Pathway Controls Cell Proliferation by Regulating the FoxO3a Transcription Factor via SGK1 Kinase
Shunsuke Mori et al.
PLOS ONE (2014)
Upregulation of micro-ribonucleic acid-128 cooperating with downregulation of PTEN confers metastatic potential and unfavorable prognosis in patients with primary osteosarcoma
Zheng Tian et al.
ONCOTARGETS AND THERAPY (2014)
Molecular mechanisms of chemoresistance in osteosarcoma
Hongtao He et al.
ONCOLOGY LETTERS (2014)
Glaucocalyxin A, a negative Akt regulator, specifically induces apoptosis in human brain glioblastoma U87MG cells
Xian Xiao et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2013)
Targeted Regulation of PI3K/Akt/mTOR/NF-κB Signaling by Indole Compounds and their Derivatives: Mechanistic Details and Biological Implications for Cancer Therapy
Aamir Ahmad et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2013)
Inhibition of fatty acid synthase suppresses U-2 OS cell invasion and migration via downregulating the activity of HER2/PI3K/AKT signaling pathway in vitro
Tao Fang Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
MiR-223/Ect2/p21 signaling regulates osteosarcoma cell cycle progression and proliferation
Jianli Xu et al.
BIOMEDICINE & PHARMACOTHERAPY (2013)
Insulin resistance and cancer: the role of insulin and IGFs
Sefirin Djiogue et al.
ENDOCRINE-RELATED CANCER (2013)
Core promoter analysis of porcine Six1 gene and its regulation of the promoter activity by CpG methylation
Wangjun Wu et al.
GENE (2013)
PHD4 Stimulates Tumor Angiogenesis in Osteosarcoma Cells via TGF-α
Anne Klotzsche-von Ameln et al.
MOLECULAR CANCER RESEARCH (2013)
Nutrient regulation of the mTOR Complex 1 signaling pathway
Sang Gyun Kim et al.
MOLECULES AND CELLS (2013)
MicroRNA-221 Induces Cell Survival and Cisplatin Resistance through PI3K/Akt Pathway in Human Osteosarcoma
Guangyi Zhao et al.
PLOS ONE (2013)
MiR-133b Is Down-Regulated in Human Osteosarcoma and Inhibits Osteosarcoma Cells Proliferation, Migration and Invasion, and Promotes Apoptosis
Huafu Zhao et al.
PLOS ONE (2013)
Insulin-like growth factor-1 induces lymphangiogenesis and facilitates lymphatic metastasis in colorectal cancer
Zhen-Jun Li et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2013)
Heat Shock Protein 90B1 Plays an Oncogenic Role and is a Target of microRNA-223 in Human Osteosarcoma
Guodong Li et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2012)
Overexpression of factor inhibiting HIF-1 enhances vessel maturation and tumor growth via platelet-derived growth factor-C
Aleksandar Kuzmanov et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Modeling human osteosarcoma in mice through 3AB-OS cancer stem cell xenografts
Riccardo Di Fiore et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2012)
PI3K-independent AKT activation in cancers: A treasure trove for novel therapeutics
Kiran Mahajan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2012)
Development of PI3K/AKT/mTOR Pathway Inhibitors and Their Application in Personalized Therapy for Non-Small-Cell Lung Cancer
Vassiliki Papadimitrakopoulou
JOURNAL OF THORACIC ONCOLOGY (2012)
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
Sophia Y. Lunt et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Twenty Years of Follow-Up of Survivors of Childhood Osteosarcoma
Rajaram Nagarajan et al.
CANCER (2011)
Hispidulin, a small flavonoid molecule, suppresses the angiogenesis and growth of human pancreatic cancer by targeting vascular endothelial growth factor receptor 2-mediated PI3K/Akt/mTOR signaling pathway
Lijun He et al.
CANCER SCIENCE (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Appraising the Current Role of Chemotherapy for the Treatment of Sarcoma
David R. D'Adamo
SEMINARS IN ONCOLOGY (2011)
Glaucocalyxin A induces apoptosis in human leukemia HL-60 cells through mitochondria-mediated death pathway
Li Wen Gao et al.
TOXICOLOGY IN VITRO (2011)
Homeoprotein Six1 Increases TGF-β Type I Receptor and Converts TGF-β Signaling from Suppressive to Supportive for Tumor Growth
Douglas S. Micalizzi et al.
CANCER RESEARCH (2010)
Autocrine VEGF Signaling Synergizes with EGFR in Tumor Cells to Promote Epithelial Cancer Development
Beate M. Lichtenberger et al.
CELL (2010)
Eaten alive: a history of macroautophagy
Zhifen Yang et al.
NATURE CELL BIOLOGY (2010)
The emerging mechanisms of isoform-specific PI3K signalling
Bart Vanhaesebroeck et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
MicroRNAs in Cancer
Yong Sun Lee et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2009)
The binding of von Willebrand factor type C domains of Chordin family proteins to BMP-2 and Tsg is mediated by their SD1 subdomain
Takuo Fujisawa et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
MicroRNAs: Target Recognition and Regulatory Functions
David P. Bartel
CELL (2009)
Targeting the phosphoinositide 3-kinase pathway in cancer
Pixu Liu et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
p21 in cancer: intricate networks and multiple activities
Tarek Abbas et al.
NATURE REVIEWS CANCER (2009)
The BCL-2 protein family: opposing activities that mediate cell death
Richard J. Youle et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy
Isabel M. Chu et al.
NATURE REVIEWS CANCER (2008)
Adjuvant and neoadjuvant combination chemotherapy for osteogenic sarcoma
Stefano Ferrari et al.
CURRENT OPINION IN ONCOLOGY (2007)
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
Jeffrey A. Engelman et al.
NATURE REVIEWS GENETICS (2006)
Processing of primary microRNAs by the Microprocessor complex
AM Denli et al.
NATURE (2004)
PI3K-Akt pathway: Its functions and alterations in human cancer
M Osaki et al.
APOPTOSIS (2004)
Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane
SM Maira et al.
SCIENCE (2001)
PKB/AKT: Functional insights from genetic models
MP Scheid et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)