Related references
Note: Only part of the references are listed.Synovial joint-on-a-chip for modeling arthritis: progress, pitfalls, and potential
Zhong Alan Li et al.
TRENDS IN BIOTECHNOLOGY (2023)
Joint-on-chip platforms: entering a new era of in vitro models for arthritis
Carlo Alberto Paggi et al.
NATURE REVIEWS RHEUMATOLOGY (2022)
Mechanosignalling in cartilage: an emerging target for the treatment of osteoarthritis
Tom Hodgkinson et al.
NATURE REVIEWS RHEUMATOLOGY (2022)
Mesenchymal stromal cell-based therapy for cartilage regeneration in knee osteoarthritis
Xiao-Na Xiang et al.
STEM CELL RESEARCH & THERAPY (2022)
Emerging microfluidics-enabled platforms for osteoarthritis management: from benchtop to bedside
Zhou Zou et al.
THERANOSTICS (2022)
Pump-free microfluidic magnetic levitation approach for density-based cell characterization
Qiu-Hua Gao et al.
BIOSENSORS & BIOELECTRONICS (2022)
Human organs-on-chips for disease modelling, drug development and personalized medicine
Donald E. Ingber
NATURE REVIEWS GENETICS (2022)
Advances in organ-on-a-chip systems for modelling joint tissue and osteoarthritic diseases
L. Banh et al.
OSTEOARTHRITIS AND CARTILAGE (2022)
Capturing Essential Physiological Aspects of Interacting Cartilage and Bone Tissue with Osteoarthritis Pathophysiology: A Human Osteochondral Unit-on-a-Chip Model
Margo Tuerlings et al.
ADVANCED MATERIALS TECHNOLOGIES (2022)
Highly Organized Porous Gelatin-Based Scaffold by Microfluidic 3D-Foaming Technology and Dynamic Culture for Cartilage Tissue Engineering
Hsia-Wei Liu et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
The Role of Epigenetic in Dental and Oral Regenerative Medicine by Different Types of Dental Stem Cells: A Comprehensive Overview
Ahmed Hussain et al.
STEM CELLS INTERNATIONAL (2022)
A guide to the organ-on-a-chip
Chak Ming Leung et al.
NATURE REVIEWS METHODS PRIMERS (2022)
Models of Osteoarthritis: Relevance and New Insights
Hasmik Jasmine Samvelyan et al.
CALCIFIED TISSUE INTERNATIONAL (2021)
Encapsulated Mesenchymal Stromal Cell Microbeads Promote Endogenous Regeneration of Osteoarthritic Cartilage Ex Vivo
Neety Sahu et al.
ADVANCED HEALTHCARE MATERIALS (2021)
Osteoarthritic Subchondral Bone Release Exosomes That Promote Cartilage Degeneration
Xiaoxin Wu et al.
CELLS (2021)
Mechanical Performance of 3D-Printed Biocompatible Polycarbonate for Biomechanical Applications
Giovanni Gomez-Gras et al.
POLYMERS (2021)
Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets
Dominika E. Nanus et al.
EBIOMEDICINE (2021)
Hypoxia induces DOT1L in articular cartilage to protect against osteoarthritis
Astrid De Roover et al.
JCI INSIGHT (2021)
A Facile and Scalable Hydrogel Patterning Method for Microfluidic 3D Cell Culture and Spheroid-in-Gel Culture Array
Chengxun Su et al.
BIOSENSORS-BASEL (2021)
Development of a human osteochondral construct on a microfluidic chip – to advance functional studies of osteoarthritis risk genes
M. Tuerlings et al.
OSTEOARTHRITIS AND CARTILAGE (2021)
Macro, Micro, and Molecular. Changes of the Osteochondral Interface in Osteoarthritis Development
Xiwei Fan et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Drug Evaluation Based on a Multi-Channel Cell Chip with a Horizontal Co-Culture
Gyeong-Ji Kim et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Osteocyte Dysfunction in Joint Homeostasis and Osteoarthritis
Lanlan Zhang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Recapitulating monocyte extravasation to the synovium in an organotypic microfluidic model of the articular joint
Carlotta Mondadori et al.
BIOFABRICATION (2021)
Nanocellulose-Based Scaffolds for Chondrogenic Differentiation and Expansion
Marcin Szustak et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)
Establishment of a human three-dimensional chip-based chondro-synovial coculture joint model for reciprocal cross talk studies in arthritis research
Mario Rothbauer et al.
LAB ON A CHIP (2021)
Survival and Proliferation under Severely Hypoxic Microenvironments Using Cell-Laden Oxygenating Hydrogels
Shabir Hassan et al.
JOURNAL OF FUNCTIONAL BIOMATERIALS (2021)
Modulation of inflammation by anti-TNF α mAb-dendrimer nanoparticles loaded in tyramine-modified gellan gum hydrogels in a cartilage-on-a-chip model
I. M. Oliveira et al.
JOURNAL OF MATERIALS CHEMISTRY B (2021)
Microenvironment in subchondral bone: predominant regulator for the treatment of osteoarthritis
Wenhui Hu et al.
ANNALS OF THE RHEUMATIC DISEASES (2021)
Subchondral bone microenvironment in osteoarthritis and pain
Yan Hu et al.
BONE RESEARCH (2021)
The emerging role of fibroblast-like synoviocytes-mediated synovitis in osteoarthritis: An update
Dafei Han et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
Porous Scaffold Design for Additive Manufacturing in Orthopedics: A Review
Hao Chen et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)
Monolithic microfluidic platform for exerting gradients of compression on cell-laden hydrogels, and application to a model of the articular cartilage
Carlo Alberto Paggi et al.
SENSORS AND ACTUATORS B-CHEMICAL (2020)
Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis
Ching-Heng Chou et al.
SCIENTIFIC REPORTS (2020)
Knockdown of exosome-mediated lnc-PVT1 alleviates lipopolysaccharide-induced osteoarthritis progression by mediating the HMGB1/TLR4/NF-κB pathway via miR-93-5p
Yong Meng et al.
MOLECULAR MEDICINE REPORTS (2020)
Design and Evaluation of an Osteogenesis-on-a-Chip Microfluidic Device Incorporating 3D Cell Culture
Hossein Bahmaee et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)
Utility of direct 3D co-culture model for chondrogenic differentiation of mesenchymal stem cells on hyaluronan scaffold (Hyaff-11)
Iwona Deszcz et al.
REGENERATIVE BIOMATERIALS (2020)
Biocompatible PEGDA Resin for 3D Printing
Chandler Warr et al.
ACS APPLIED BIO MATERIALS (2020)
Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies
Aiyong Cui et al.
ECLINICALMEDICINE (2020)
Is It Time to Start Transitioning From 2D to 3D Cell Culture?
Caleb Jensen et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2020)
2dyn/cm2 shear force upregulates kruppel-like factor 4 expression in human chondrocytes to inhibit the interleukin-1β-activated nuclear factor-κB
Shun-Fu Chang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip
Sasan Jalili-Firoozinezhad et al.
NATURE BIOMEDICAL ENGINEERING (2019)
Human Ocular Angiogenesis-Inspired Vascular Models on an Injection-Molded Microfluidic Chip
Jihoon Ko et al.
ADVANCED HEALTHCARE MATERIALS (2019)
Hyperphysiological compression of articular cartilage induces an osteoarthritic phenotype in a cartilage-on-a-chip model
Paola Occhetta et al.
NATURE BIOMEDICAL ENGINEERING (2019)
Load-induced osteoarthritis on a chip
Riccardo Gottardi
NATURE BIOMEDICAL ENGINEERING (2019)
Models of osteoarthritis: the good, the bad and the promising
P. J. Cope et al.
OSTEOARTHRITIS AND CARTILAGE (2019)
Osteochondral Tissue Chip Derived From iPSCs: Modeling OA Pathologies and Testing Drugs
Zixuan Lin et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2019)
Modelling cancer in microfluidic human organs-on-chips
Alexandra Sontheimer-Phelps et al.
NATURE REVIEWS CANCER (2019)
Microfluidic nutrient gradient-based three-dimensional chondrocyte culture-on-a-chip as an in vitro equine arthritis model
J. Rosser et al.
MATERIALS TODAY BIO (2019)
Decellularization of human donor aortic and pulmonary valved conduits using low concentration sodium dodecyl sulfate
Tayyebeh Vafaee et al.
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2018)
Ex vivo replication of phenotypic functions of osteocytes through biomimetic 3D bone tissue construction
Qiaoling Sun et al.
BONE (2018)
Extracellular vesicles in cartilage homeostasis and osteoarthritis
Shigeru Miyaki et al.
CURRENT OPINION IN RHEUMATOLOGY (2018)
Mimicking the 3D biology of osteochondral tissue with microfluidic-based solutions: breakthroughs towards boosting drug testing and discovery
Mariana R. Carvalho et al.
DRUG DISCOVERY TODAY (2018)
Hypoxic Three-Dimensional Cellular Network Construction Replicates Ex Vivo the Phenotype of Primary Human Osteocytes
Saba Choudhary et al.
TISSUE ENGINEERING PART A (2018)
A microfluidic chip-based co-culture of fibroblast-like synoviocytes with osteoblasts and osteoclasts to test bone erosion and drug evaluation
Hui-Peng Ma et al.
ROYAL SOCIETY OPEN SCIENCE (2018)
Maintenance of chondrocyte phenotype during expansion on PLLA microtopographies
Elisa Costa et al.
JOURNAL OF TISSUE ENGINEERING (2018)
Automated 3D bioassembly of micro-tissues for biofabrication of hybrid tissue engineered constructs
N. V. Mekhileri et al.
BIOFABRICATION (2018)
Harpagoside suppresses IL-6 expression in primary human osteoarthritis chondrocytes
Abdul Haseeb et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2017)
Novel treatment strategies in rheumatoid arthritis
Gerd R. Burmester et al.
LANCET (2017)
Modeling Physiological Events in 2D vs. 3D Cell Culture
Kayla Duval et al.
PHYSIOLOGY (2017)
Effects of Type I Collagen Concentration in Hydrogel on the Growth and Phenotypic Expression of Rat Chondrocytes
Guang-Zhen Jin et al.
TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2017)
Dorsal root ganglion neurons regulate the transcriptional and translational programs of osteoblast differentiation in a microfluidic platform
Diana Isabel Silva et al.
CELL DEATH & DISEASE (2017)
Effects of insulin-like growth factor 1 and basic fibroblast growth factor on the morphology and proliferation of chondrocytes embedded in Matrigel in a microfluidic platform
Yuancheng Li et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2017)
Effects of Type I Collagen Concentration in Hydrogel on the Growth and Phenotypic Expression of Rat Chondrocytes
Guang-Zhen Jin et al.
TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2017)
Conditional Macrophage Depletion Increases Inflammation and Does Not Inhibit the Development of Osteoarthritis in Obese Macrophage Fas-Induced Apoptosis-Transgenic Mice
Chia-Lung Wu et al.
ARTHRITIS & RHEUMATOLOGY (2017)
Osteoarthritis: toward a comprehensive understanding of pathological mechanism
Di Chen et al.
BONE RESEARCH (2017)
Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis
Masashi Nagao et al.
SCIENTIFIC REPORTS (2017)
A pump-free microfluidic 3D perfusion platform for the efficient differentiation of human hepatocyte-like cells
Louis Jun Ye Ong et al.
BIOTECHNOLOGY AND BIOENGINEERING (2017)
Design and characterization of hydrogel-based microfluidic devices with biomimetic solute transport networks
Hyung-Jun Koo et al.
BIOMICROFLUIDICS (2017)
Wnt signaling in cartilage development and diseases: lessons from animal studies
Yu Usami et al.
LABORATORY INVESTIGATION (2016)
Microfluidics-based optimization of neuroleukin-mediated regulation of articular chondrocyte proliferation
Kang Tian et al.
MOLECULAR MEDICINE REPORTS (2016)
Restraining non-specific adsorption of protein using Parylene C-caulked polydimethylsiloxane
Yaoping Liu et al.
BIOMICROFLUIDICS (2016)
Animal models of osteoarthritis: classification, update, and measurement of outcomes
Emmanuel L. Kuyinu et al.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH (2016)
Bone-cartilage crosstalk: a conversation for understanding osteoarthritis
David M. Findlay et al.
BONE RESEARCH (2016)
A pump-free membrane-controlled perfusion microfluidic platform
Vasiliy N. Goral et al.
Biomicrofluidics (2015)
Articular cartilage zonal differentiation via 3D Second-Harmonic Generation imaging microscopy
Rajeev Chaudhary et al.
CONNECTIVE TISSUE RESEARCH (2015)
Hypoxia combined with spheroid culture improves cartilage specific function in chondrocytes
Yang Shi et al.
INTEGRATIVE BIOLOGY (2015)
A multi-organ chip co-culture of neuro spheres and liver equivalents for long-term substance testing
Eva-Maria Materne et al.
JOURNAL OF BIOTECHNOLOGY (2015)
A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
Ilka Maschmeyer et al.
LAB ON A CHIP (2015)
Organs-on-chips at the frontiers of drug discovery
Eric W. Esch et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
Inflammation in joint injury and post-traumatic osteoarthritis
J. Lieberthal et al.
OSTEOARTHRITIS AND CARTILAGE (2015)
Animal Models of Osteoarthritis: Comparisons and Key Considerations
A. M. McCoy
VETERINARY PATHOLOGY (2015)
Oxygen control with microfluidics
Martin D. Brennan et al.
LAB ON A CHIP (2014)
Stem Cell-Based Microphysiological Osteochondral System to Model Tissue Response to Interleukin-1β
Hang Lin et al.
MOLECULAR PHARMACEUTICS (2014)
Microfluidic organs-on-chips
Sangeeta N. Bhatia et al.
NATURE BIOTECHNOLOGY (2014)
A Microfluidic-Based Multi-Shear Device for Investigating the Effects of Low Fluid-Induced Stresses on Osteoblasts
Weiliang Yu et al.
PLOS ONE (2014)
Successful therapies for Alzheimer's disease: why so many in animal models and none in humans?
Rafael Franco et al.
FRONTIERS IN PHARMACOLOGY (2014)
Fluid shear stress-induced osteoarthritis: roles of cyclooxygenase-2 and its metabolic products in inducing the expression of proinflammatory cytokines and matrix metalloproteinases
Pu Wang et al.
FASEB JOURNAL (2013)
A Comparison of Three-Dimensional Culture Systems to Evaluate In Vitro Chondrogenesis of Equine Bone Marrow-Derived Mesenchymal Stem Cells
Ashlee E. Watts et al.
TISSUE ENGINEERING PART A (2013)
The use of animal as models: ethical considerations
Neil Levy
INTERNATIONAL JOURNAL OF STROKE (2012)
A Library of Tunable Agarose Carbomer-Based Hydrogels for Tissue Engineering Applications: The Role of Cross-Linkers
Filippo Rossi et al.
JOURNAL OF APPLIED POLYMER SCIENCE (2012)
A proposed model of naturally occurring osteoarthritis in the domestic rabbit
Boaz Arzi et al.
LAB ANIMAL (2012)
Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels
Yoojin Shin et al.
NATURE PROTOCOLS (2012)
A Review of Translational Animal Models for Knee Osteoarthritis
Martin H. Gregory et al.
ARTHRITIS (2012)
Single-Monomer Formulation of Polymerized Polyethylene Glycol Diacrylate as a Nonadsorptive Material for Microfluidics
Chad I. Rogers et al.
ANALYTICAL CHEMISTRY (2011)
A 3D cartilage - Inflammatory cell culture system for the modeling of human osteoarthritis
Lin Sun et al.
BIOMATERIALS (2011)
Generation of oxygen gradients in microfluidic devices for cell culture using spatially confined chemical reactions
Yung-Ann Chen et al.
LAB ON A CHIP (2011)
Coculture of Human Mesenchymal Stem Cells and Articular Chondrocytes Reduces Hypertrophy and Enhances Functional Properties of Engineered Cartilage
Liming Bian et al.
TISSUE ENGINEERING PART A (2011)
From 3D cell culture to organs-on-chips
Dongeun Huh et al.
TRENDS IN CELL BIOLOGY (2011)
A Central Role for Hypoxic Signaling in Cartilage, Bone, and Hematopoiesis
Erinn B. Rankin et al.
Current Osteoporosis Reports (2011)
Clinical and ultrasonographic predictors of joint replacement for knee osteoarthritis: results from a large, 3-year, prospective EULAR study
P. G. Conaghan et al.
ANNALS OF THE RHEUMATIC DISEASES (2010)
Shear-induced Interleukin-6 Synthesis in Chondrocytes ROLES OF E PROSTANOID (EP) 2 AND EP3 IN cAMP/PROTEIN KINASE A-AND PI3-K/Akt-DEPENDENT NF-κB ACTIVATION
Pu Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the guinea pig
V. B. Kraus et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
Angiogenesis in osteoarthritis
Sadaf Ashraf et al.
CURRENT OPINION IN RHEUMATOLOGY (2008)
Hypoxia-inducible factor-1α regulates matrix metalloproteinase-1 activity in human bone marrow-derived mesenchymal stem cells
Jiunn-Liang Lin et al.
FEBS LETTERS (2008)
Animal Models of Osteoarthritis
Christopher B. Little et al.
CURRENT RHEUMATOLOGY REVIEWS (2008)
Hypoxia and osteoarthritis: how chondrocytes survive hypoxic environments
David Pfander et al.
CURRENT OPINION IN RHEUMATOLOGY (2007)
Universal microfluidic gradient generator
Daniel Irimia et al.
ANALYTICAL CHEMISTRY (2006)
Elucidating in vitro cell-cell interaction using a microfluidic coculture system
CW Wei et al.
BIOMEDICAL MICRODEVICES (2006)
Study of osteoblastic cells in a microfluidic environment
E Leclerc et al.
BIOMATERIALS (2006)
The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis
Jan Bondeson et al.
ARTHRITIS RESEARCH & THERAPY (2006)
Co-culture of osteoblasts and chondrocytes modulates cellular differentiation in vitro
J Jiang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Dynamic osmotic loading of chondrocytes using a novel microfluidic device
PG Chao et al.
JOURNAL OF BIOMECHANICS (2005)
Osteoarthritis - An untreatable disease?
HA Wieland et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Is osteoarthritis a systemic disorder of bone?
J Rogers et al.
ARTHRITIS AND RHEUMATISM (2004)
Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis
AB Blom et al.
OSTEOARTHRITIS AND CARTILAGE (2004)
Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation
PLEM van Lent et al.
ARTHRITIS AND RHEUMATISM (2004)
Quantitative structural organization of normal adult human articular cartilage
EB Hunziker et al.
OSTEOARTHRITIS AND CARTILAGE (2002)
Normal and pathological adaptations of articular cartilage to joint loading
JPA Arokoski et al.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS (2000)