Related references
Note: Only part of the references are listed.A partial reduction of Drp1 improves cognitive behavior and enhances mitophagy, autophagy and dendritic spines in a transgenic Tau mouse model of Alzheimer disease
Ramesh Kandimalla et al.
HUMAN MOLECULAR GENETICS (2022)
Dual-process brain mitochondria isolation preserves function and clarifies protein composition
Maria F. Noterman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
CRMP2 Is Involved in Regulation of Mitochondrial Morphology and Motility in Neurons
Tatiana Brustovetsky et al.
CELLS (2021)
Involvement of CRMP2 in Regulation of Mitochondrial Morphology and Motility in Huntington's Disease
Tatiana Brustovetsky et al.
CELLS (2021)
Alzheimer disease
David S. Knopman et al.
NATURE REVIEWS DISEASE PRIMERS (2021)
Druggability of CRMP2 for Neurodegenerative Diseases
Rajesh Khanna et al.
ACS CHEMICAL NEUROSCIENCE (2020)
Collapsin Response Mediator Proteins: Novel Targets for Alzheimer's Disease
Tam T. Quach et al.
JOURNAL OF ALZHEIMERS DISEASE (2020)
Mitochondria' dynamics and transport in Alzheimer's disease
Padraig J. Flannery et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2019)
Mitochondria as Potential Targets in Alzheimer Disease Therapy: An Update
Giovanna Cenini et al.
FRONTIERS IN PHARMACOLOGY (2019)
Alzheimer's disease
C. A. Lane et al.
EUROPEAN JOURNAL OF NEUROLOGY (2018)
Amyloid-beta-dependent phosphorylation of collapsin response mediator protein-2 dissociates kinesin in Alzheimer's disease
Sara H. Mokhtar et al.
NEURAL REGENERATION RESEARCH (2018)
Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer's Disease
Isaura V. A. Martins et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer's disease
P. Hemachandra Reddy et al.
HUMAN MOLECULAR GENETICS (2017)
Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model
Wenzhang Wang et al.
HUMAN MOLECULAR GENETICS (2017)
Influence of Transgenic Metallothionein-1 on Gliosis, CA1 Neuronal Loss, and Brain Metal Levels of the Tg2576 Mouse Model of Alzheimer's Disease
Gemma Comes et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Oxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease
Eric Tonnies et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Mitochondria-Division Inhibitor 1 Protects Against Amyloid-beta induced Mitochondrial Fragmentation and Synaptic Damage in Alzheimer's Disease
P. Hemachandra Reddy et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Amyloid-Beta and Phosphorylated Tau Accumulations Cause Abnormalities at Synapses of Alzheimer's disease Neurons
Ravi Rajmohan et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model
Seung Hyun Baek et al.
JOURNAL OF NEUROSCIENCE (2017)
A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer's Disease and Its Target Molecule
Zhiyou Yang et al.
FRONTIERS IN PHARMACOLOGY (2017)
Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases
Ju Gao et al.
ANTIOXIDANTS (2017)
(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5
Aubin Moutal et al.
MOLECULAR NEUROBIOLOGY (2016)
(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology
Aubin Moutal et al.
PAIN (2016)
Mitochondrial division and fusion in metabolism
Madhuparna Roy et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease
Ignacio Pedros et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
Collapsin Response Mediator Protein 2 (CRMP2) Interacts with N-Methyl-D-aspartate (NMDA) Receptor and Na+/Ca2+ Exchanger and Regulates Their Functional Activity
Tatiana Brustovetsky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Mitochondrial trafficking and anchoring in neurons: New insight and implications
Zu-Hang Sheng
JOURNAL OF CELL BIOLOGY (2014)
The functionalized amino acid (S)-Lacosannide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth
Sarah M. Wilson et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Role of mitochondrial homeostasis and dynamics in Alzheimer's disease
J. Eva Selfridge et al.
NEUROBIOLOGY OF DISEASE (2013)
Amyloid-β25-35 induces impairment of cognitive function and long-term potentiation through phosphorylation of collapsin response mediator protein 2
Toshinari Isono et al.
NEUROSCIENCE RESEARCH (2013)
Deregulated Cdk5 Activity Is Involved in Inducing Alzheimer's Disease
Varsha Shukla et al.
ARCHIVES OF MEDICAL RESEARCH (2012)
Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics
P. Hemachandra Reddy et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)
Roles of Glycogen Synthase Kinase 3 in Alzheimer's Disease
Zhiyou Cai et al.
CURRENT ALZHEIMER RESEARCH (2012)
Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimers disease neurons: implications for mitochondrial dysfunction and neuronal damage
Maria Manczak et al.
HUMAN MOLECULAR GENETICS (2012)
Phosphorylation of CRMP2 (Collapsin Response Mediator Protein 2) Is Involved in Proper Dendritic Field Organization
Naoya Yamashita et al.
JOURNAL OF NEUROSCIENCE (2012)
Defects in Mitochondrial Dynamics and Metabolomic Signatures of Evolving Energetic Stress in Mouse Models of Familial Alzheimer's Disease
Eugenia Trushina et al.
PLOS ONE (2012)
Opening Pandora's jar: a primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders
Rajesh Khanna et al.
FUTURE NEUROLOGY (2012)
Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons
Marcus J. Calkins et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease
P. Hemachandra Reddy
BRAIN RESEARCH (2011)
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
Maria Manczak et al.
HUMAN MOLECULAR GENETICS (2011)
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
Marcus J. Calkins et al.
HUMAN MOLECULAR GENETICS (2011)
CRMP2 Hyperphosphorylation is Characteristic of Alzheimer's Disease and not a Feature Common to Other Neurodegenerative Diseases
Ritchie Williamson et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Neuroprotection against Traumatic Brain Injury by a Peptide Derived from the Collapsin Response Mediator Protein 2 (CRMP2)
Joel M. Brittain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
The memory enhancing effect of the APP-derived tripeptide Ac-rER is mediated through CRMP2
Radmila Mileusnic et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Collapsin Response Mediator Protein-2: An Emerging Pathologic Feature and Therapeutic Target for Neurodisease Indications
Kenneth Hensley et al.
MOLECULAR NEUROBIOLOGY (2011)
Mitochondrial dynamics in cell death and neurodegeneration
Dong-Hyung Cho et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
Mitofusin 2 Is Necessary for Transport of Axonal Mitochondria and Interacts with the Miro/Milton Complex
Albert Misko et al.
JOURNAL OF NEUROSCIENCE (2010)
Stimulation of glutamate receptors in cultured hippocampal neurons causes Ca2+-dependent mitochondrial contraction
Tatiana Brustovetsky et al.
CELL CALCIUM (2009)
Increased CRMP2 Phosphorylation is Observed in Alzheimer's Disease; Does this Tell us Anything About Disease Development?
M. P. M. Soutar et al.
CURRENT ALZHEIMER RESEARCH (2009)
Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
Hsiuchen Chen et al.
HUMAN MOLECULAR GENETICS (2009)
Semaphorin3A Signaling Mediated by Fyn-dependent Tyrosine Phosphorylation of Collapsin Response Mediator Protein 2 at Tyrosine 32
Yutaka Uchida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Regulation of N-type voltage-gated calcium channels (Cav2.2) and transmitter release by collapsin response mediator protein-2 (CRMP-2) in sensory neurons
Xian Xuan Chi et al.
JOURNAL OF CELL SCIENCE (2009)
CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity
Nariko Arimura et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
Xinglong Wang et al.
JOURNAL OF NEUROSCIENCE (2009)
Novel procedure to investigate the effect of phosphorylation on protein complex formation in vitro and in cells
Makoto Rembutsu et al.
BIOCHEMISTRY (2008)
Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species
Tianzheng Yu et al.
CARDIOVASCULAR RESEARCH (2008)
Antioxidant Therapy in Alzheimer's Disease: Theory and Practice
Gjumrakch Aliev et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2008)
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
Heng Du et al.
NATURE MEDICINE (2008)
Mutant huntingtin and mitochondrial dysfunction
Ella Bossy-Wetzel et al.
TRENDS IN NEUROSCIENCES (2008)
The beta-amyloid protein of Alzheimers disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanism
Steven Petratos et al.
BRAIN (2008)
Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression
Adam R. Cole et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Calcium-dependent spontaneously reversible remodeling of brain mitochondria
Natalia Shalbuyeva et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Kinesin-1 and dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons
AD Pilling et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Cyclin-dependent protein kinase 5 primes microtubule-associated protein tau site-specifically for glycogen synthase kinase 3β
T Li et al.
BIOCHEMISTRY (2006)
Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones
N Arimura et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain
KA Ryan et al.
JOURNAL OF CELL BIOLOGY (2005)
Excitotoxic injury to mitochondria isolated from cultured neurons
YE Kushnareva et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses
XF Guo et al.
NEURON (2005)
Tubulin and CRMP-2 complex is transported via Kinesin-1
T Kimura et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3β phosphorylation of CRMP2:: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease
Y Uchida et al.
GENES TO CELLS (2005)
GSK-3β regulates phosphorylation of CRMP-2 and neuronal polarity
T Yoshimura et al.
CELL (2005)
Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease
C Schmitz et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Cdk5, a therapeutic target for Alzheimer's disease?
LH Tsai et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2004)
GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons
AR Cole et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cell cultures from animal models of Alzheimer's disease as a tool for faster screening and testing of drug efficacy
F Trinchese et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2004)
Mitochondrial fission in apoptosis, neurodegeneration and aging
E Bossy-Wetzel et al.
CURRENT OPINION IN CELL BIOLOGY (2003)
Collapsin response mediator proteins (CRMPs) - Involvement in nervoust system development and adult neurodegenerative disorders
E Charrier et al.
MOLECULAR NEUROBIOLOGY (2003)
Axonal transport of mitochondria to synapses depends on Milton, a novel Drosophila protein
RS Stowers et al.
NEURON (2002)
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells
E Smirnova et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
Phosphorylation of collapsin response mediator protein-2 by Rho-kinase -: Evidence for two separate signaling pathways for growth cone collapse
N Arimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Neurofibrillary tangle-associated collapsin response mediator protein-2 (CRMP-2) is highly phosphorylated on Thr-509, Ser-518, and Ser-522
YJ Gu et al.
BIOCHEMISTRY (2000)
Share Paper
