4.6 Review

Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review

Journal

CELLS
Volume 12, Issue 6, Pages -

Publisher

MDPI
DOI: 10.3390/cells12060951

Keywords

stem cells; androgenic alopecia; female pattern hair loss; mesenchymal stem cell; follicle-derived stem cells; alopecia; male pattern hair loss; tissue regeneration; clinical application

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Androgenetic alopecia is a common condition causing hair loss in both men and women, which can significantly affect one's psychological well-being. A systematic review was conducted to assess the efficacy of using stem cells in treating androgenetic alopecia. The review analyzed the results of using different types of stem cells compared to control treatment or other types of treatment for male and female androgenetic alopecia. The use of stem cells shows promise as an alternative or complementary therapy for androgenetic alopecia, but further research is needed for validation in larger and more diverse samples.
Androgenetic alopecia is a condition that results in hair loss in both men and women. This can have a significant impact on a person's psychological well-being, which can lead to a decreased quality of life. We conducted a systematic review to evaluate the efficacy of using stem cells in androgenic alopecia. The search was conducted in MEDLINE via PubMed, Web of Science, and Scopus databases. The review was performed on data pertaining to the efficacy of using different types of stem cells in androgenic alopecia: quantitative results of stem cell usage were compared to the control treatment or, different types of treatment for female and male androgenetic alopecia. Of the outcomes, the density of hair was analyzed. Fourteen articles were selected for this review. During and after treatment with stem cells, no major side effects were reported by patients with alopecia. The use of stem cells in androgenic alopecia seems to be a promising alternative to the standard treatment or it could play the role of complementary therapy to improve the effect of primary treatment. However, these results should be interpreted with caution until they can be reproduced in larger and more representative samples.

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