4.6 Review

Potential Role of Circulating miRNAs for Breast Cancer Management in the Neoadjuvant Setting: A Road to Pave

Related references

Note: Only part of the references are listed.
Article Medicine, General & Internal

Development and validation of the new HER2DX assay for predicting pathological response and survival outcome in early-stage HER2-positive breast cancer

Aleix Prat et al.

Summary: A new HER2DX risk score and pCR score have been developed to accurately predict survival and treatment response in early-stage HER2-positive breast cancer.

EBIOMEDICINE (2022)

Review Oncology

Circulating miRNAs in Breast Cancer Diagnosis and Prognosis

Barbara Cardinali et al.

Summary: This review discusses the potential application of circulating microRNAs (miRNAs) as diagnostic and monitoring biomarkers in breast cancer. It highlights the advantages and challenges that need to be addressed. Although further studies are needed to support their clinical utility, miRNAs could represent novel tools for breast cancer management.

CANCERS (2022)

Article Surgery

Evaluating the Role of Circulating MicroRNAs to Aid Therapeutic Decision Making for Neoadjuvant Chemotherapy in Breast Cancer A Prospective, Multicenter Clinical Trial

Matthew G. Davey et al.

Summary: This study demonstrates the potential value of circulating miRNA measurement in predicting response to neoadjuvant chemotherapy (NAC). By analyzing the correlation between miRNA expression trends and treatment response, miRNAs that are associated with NAC response were identified. These findings have the potential to inform personalized treatment decision-making.

ANNALS OF SURGERY (2022)

Review Oncology

miRNAs as therapeutic predictors and prognostic biomarkers of neoadjuvant chemotherapy in breast cancer: a systematic review and meta-analysis

Zhuo Zhang et al.

Summary: The study found that many miRNAs may be associated with NAC response and prognosis in BC patients. Further well-designed studies are needed to elucidate the molecular mechanisms underlying these associations.

BREAST CANCER RESEARCH AND TREATMENT (2022)

Review Oncology

Circulating microRNAs: Challenges with their use as liquid biopsy biomarkers

Satoko Takizawa et al.

Summary: Circulating miRNA is a potential biomarker for liquid biopsy, but its levels are influenced by various factors. Research into these factors is ongoing, but more evidence is needed to draw definite conclusions.

CANCER BIOMARKERS (2022)

Review Oncology

Panels of circulating microRNAs as potential diagnostic biomarkers for breast cancer: a systematic review and meta-analysis

Thu H. N. Nguyen et al.

Summary: This study identified 8 potential circulating miRNAs as diagnostic biomarkers for breast cancer (BC) and developed two diagnostic models with high accuracy. However, the miRNA panels need further validation in large case-control studies for clinical use.

BREAST CANCER RESEARCH AND TREATMENT (2022)

Article Biochemistry & Molecular Biology

Circulating Small EVs miRNAs as Predictors of Pathological Response to Neo-Adjuvant Therapy in Breast Cancer Patients

Oana Baldasici et al.

Summary: miRNAs expression in plasma sEVs showed no correlation with tissue samples, but can predict pathological response of BC to NAT.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Oncology

Circulating Exosomal microRNAs as Predictive Biomarkers of Neoadjuvant Chemotherapy Response in Breast Cancer

Valentina K. Todorova et al.

Summary: This study investigated the potential of circulating exosomal microRNAs to predict pathological complete response (pCR) in breast cancer patients undergoing neoadjuvant chemotherapy (NACT). Several microRNAs were found to be associated with pCR and correlated with survival, subtype, and metastasis in breast cancer.

CURRENT ONCOLOGY (2022)

Review Cell Biology

microRNAstrand selection: Unwinding the rules

Jeffrey C. Medley et al.

Summary: miRNAs play a central role in regulating gene expression by targeting specific mRNAs for degradation or translational repression. The process of miRNA strand selection determines the specificity of miRISC towards its targets, and aberrant strand selection can lead to altered gene regulation in diseases. Understanding the rules governing miRNA strand selection can shed light on disease mechanisms and potential therapeutic interventions.

WILEY INTERDISCIPLINARY REVIEWS-RNA (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Oncology

Circulating microRNAs as indicators in the prediction of neoadjuvant chemotherapy response in luminal B breast cancer

Zhuo Zhang et al.

Summary: This study focused on the predictive effect of circulating miRNAs on NAC response in luminal B breast cancer patients and identified specific miRNAs as potential markers for predicting response to NAC and prognosis in this subtype of breast cancer. Further studies are needed to explore the underlying mechanisms.

THORACIC CANCER (2021)

Review Medicine, General & Internal

Breast cancer

Sibylle Loibl et al.

Summary: Breast cancer diagnosis and treatment have become increasingly complex, incorporating various biomarkers and neoadjuvant therapies, with de-escalation schemes for radiotherapy now becoming standard practice.

LANCET (2021)

Review Biochemistry & Molecular Biology

Circulating miRNA analysis for cancer diagnostics and therapy

Lukas Valihrach et al.

MOLECULAR ASPECTS OF MEDICINE (2020)

Review Oncology

Genomic Signatures in Luminal Breast Cancer

Julian Puppe et al.

BREAST CARE (2020)

Review Cell Biology

Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease

Marcelo A. Mori et al.

CELL METABOLISM (2019)

Article Cell Biology

Extracellular RNA profiles with human age

Douglas F. Dluzen et al.

AGING CELL (2018)

Article Obstetrics & Gynecology

Serum levels of circulating miRNA-21, miRNA-10b and miRNA-200c in triple-negative breast cancer patients

Sebastian Niedzwiecki et al.

GINEKOLOGIA POLSKA (2018)

Review Endocrinology & Metabolism

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

Jacob O'Brien et al.

FRONTIERS IN ENDOCRINOLOGY (2018)

Review Oncology

Exosome-encapsulated microRNAs as circulating biomarkers for breast cancer

Doireann P. Joyce et al.

INTERNATIONAL JOURNAL OF CANCER (2016)

Article Oncology

Biomarker: Predictive or Prognostic?

Karla V. Ballman

JOURNAL OF CLINICAL ONCOLOGY (2015)

Article Medical Laboratory Technology

Quantitative Measurement of Serum MicroRNA-21 Expression in Relation to Breast Cancer Metastasis in Chinese Females

Guinian Wang et al.

ANNALS OF LABORATORY MEDICINE (2015)

Review Biotechnology & Applied Microbiology

Challenges in Using Circulating miRNAs as Cancer Biomarkers

Paola Tiberio et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Article Cell Biology

Neoadjuvant Chemotherapy in Breast Cancer Patients Induces miR-34a and miR-122 Expression

Pierre Freres et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2015)

Article Biochemistry & Molecular Biology

Serum microRNA-195 is down-regulated in breast cancer: a potential marker for the diagnosis of breast cancer

Fu-long Zhao et al.

MOLECULAR BIOLOGY REPORTS (2014)

Article Hematology

Smoking alters circulating plasma microvesicle pattern and microRNA signatures

Sigrun Badrnya et al.

THROMBOSIS AND HAEMOSTASIS (2014)

Review Physiology

Does regulation of skeletal muscle function involve circulating microRNAs?

Wataru Aoi et al.

FRONTIERS IN PHYSIOLOGY (2014)

Review Medical Laboratory Technology

Pre-analytical variables in miRNA analysis

Nils Becker et al.

CLINICAL BIOCHEMISTRY (2013)

Article Cell Biology

miRNA profiling of cancer

Gianpiero Di Leva et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2013)

Article Cardiac & Cardiovascular Systems

Aspirin treatment hampers the use of plasma microRNA-126 as a biomarker for the progression of vascular disease

Hetty C. de Boer et al.

EUROPEAN HEART JOURNAL (2013)

Article Multidisciplinary Sciences

Plasma Processing Conditions Substantially Influence Circulating microRNA Biomarker Levels

Heather H. Cheng et al.

PLOS ONE (2013)

Article Oncology

Neoadjuvant treatment of breast cancer

A. M. Thompson et al.

ANNALS OF ONCOLOGY (2012)

Article Oncology

Blood Cell Origin of Circulating MicroRNAs: A Cautionary Note for Cancer Biomarker Studies

Colin C. Pritchard et al.

CANCER PREVENTION RESEARCH (2012)

Review Biochemistry & Molecular Biology

Lipid-based carriers of microRNAs and intercellular communication

Kasey C. Vickers et al.

CURRENT OPINION IN LIPIDOLOGY (2012)

Article Public, Environmental & Occupational Health

The impact of mammographic screening on breast cancer mortality in Europe: a review of observational studies

Mireille Broeders et al.

JOURNAL OF MEDICAL SCREENING (2012)

Article Medicine, Research & Experimental

De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer

Xiwei Wu et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2012)

Article Multidisciplinary Sciences

Circulating MiR-125b as a Marker Predicting Chemoresistance in Breast Cancer

Hongjiang Wang et al.

PLOS ONE (2012)

Article Hematology

Analytical challenges and technical limitations in assessing circulating MiRNAs

Anna Zampetaki et al.

THROMBOSIS AND HAEMOSTASIS (2012)

Review Cell Biology

Posttranscriptional Upregulation by MicroRNAs

Shobha Vasudevan

WILEY INTERDISCIPLINARY REVIEWS-RNA (2012)

Article Medical Laboratory Technology

Analysis of Circulating MicroRNA: Preanalytical and Analytical Challenges

Jennifer S. McDonald et al.

CLINICAL CHEMISTRY (2011)

Review Oncology

Circulating microRNAs: Association with disease and potential use as biomarkers

Glen Reid et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2011)

Review Oncology

MicroRNAs in body fluids-the mix of hormones and biomarkers

Maria Angelica Cortez et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2011)

Article Multidisciplinary Sciences

Impact of Cellular miRNAs on Circulating miRNA Biomarker Signatures

Radha Duttagupta et al.

PLOS ONE (2011)

Article Multidisciplinary Sciences

Haemolysis during Sample Preparation Alters microRNA Content of Plasma

Michaela B. Kirschner et al.

PLOS ONE (2011)

Article Multidisciplinary Sciences

Plasma miRNA as Biomarkers for Assessment of Total-Body Radiation Exposure Dosimetry

Wanchang Cui et al.

PLOS ONE (2011)

Article Multidisciplinary Sciences

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

Jason D. Arroyo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Oncology

Strengths and Limitations of Laboratory Procedures for MicroRNA Detection

Jill Koshiol et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2010)

Article Biochemistry & Molecular Biology

Export of microRNAs and microRNA-protective protein by mammalian cells

Kai Wang et al.

NUCLEIC ACIDS RESEARCH (2010)

Article Multidisciplinary Sciences

Functional delivery of viral miRNAs via exosomes

D. Michiel Pegtel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Biotechnology & Applied Microbiology

MicroRNA identification in plasma and serum: a new tool to diagnose and monitor diseases

Maria Angelica Cortez et al.

EXPERT OPINION ON BIOLOGICAL THERAPY (2009)

Review Genetics & Heredity

Causes and consequences of microRNA dysregulation in cancer

Carlo M. Croce

NATURE REVIEWS GENETICS (2009)

Review Biochemistry & Molecular Biology

Technical variables in high-throughput miRNA expression profiling: Much work remains to be done

Peter T. Nelson et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2008)

Article Multidisciplinary Sciences

Circulating microRNAs as stable blood-based markers for cancer detection

Patrick S. Mitchell et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Biotechnology & Applied Microbiology

MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype

Cherie Blenkiron et al.

GENOME BIOLOGY (2007)