4.7 Review

Severity and Longitudinal Course of Depression, Anxiety and Post-Traumatic Stress in Paediatric and Young Adult Cancer Patients: A Systematic Review and Meta-Analysis

Related references

Note: Only part of the references are listed.
Review Oncology

Natural Progression of Left Ventricular Function following Anthracyclines without Cardioprotective Therapy: A Systematic Review and Meta-Analysis

Ainsley Ryan Yan Bin Lee et al.

Summary: This PRISMA-adherent systematic review and meta-analysis aims to evaluate the progression of cardiac dysfunction and levels of natriuretic peptides, and risk of heart failure in cancer patients receiving anthracyclines. The review found that there were no significant declines in cardiac function compared to after six months of treatment cessation. Approximately one in six patients experienced significant declines in LVEF.

CANCERS (2023)

Article Psychology, Social

Prospective assessment of anxiety among pediatric oncology patients and their caregivers during the COVID-19 pandemic a cohort study

Michal Yaffe Ornstein et al.

Summary: This study aimed to assess the anxiety and emotional-behavioral difficulties among oncologic children and their caregivers during the COVID-19 pandemic. The findings showed that a certain proportion of caregivers and patients reported anxiety symptoms, but the prevalence was similar to anxiety reported following a diagnosis of pediatric malignancy. There were no significant differences between patients' self-reports and caregivers' reports in terms of anxiety and emotional-behavioral difficulties. This suggests that the psychological impact of the COVID-19 pandemic on these individuals is relatively small, but late effects still need to be monitored.

JOURNAL OF PSYCHOSOCIAL ONCOLOGY (2023)

Review Psychiatry

Depression and anxiety in older adults with cancer: Systematic review and meta-summary of risk, protective and exacerbating factors

Ainsley Ryan Yan Bin Lee et al.

Summary: This systematic review examined the risk factors of depression and anxiety in older adults with cancer. Thirty-three cohort studies were included, with 31 evaluating depression and seven evaluating anxiety. The results showed various factors in different domains that can either protect against or exacerbate depression and anxiety in this population. Understanding these factors can help policymakers tailor interventions to manage psychological distress in older adults with cancer.

GENERAL HOSPITAL PSYCHIATRY (2023)

Article Oncology

Associations of Symptom Clusters and Health Outcomes in Adult Survivors of Childhood Cancer: A Report From the St Jude Lifetime Cohort Study

Hyewon Shin et al.

Summary: The purpose of this study was to identify symptom clusters among adult survivors of childhood cancers and test their associations with health-related quality of life (HRQOL) and physical and neurocognitive performance. The study identified four clusters of symptoms, and survivors with higher symptom burden were associated with sociodemographic characteristics, treatment factors, HRQOL, and functional outcomes.

JOURNAL OF CLINICAL ONCOLOGY (2023)

Article Oncology

Post-Traumatic Stress Symptoms in Adolescent Hodgkin Lymphoma Survivors: A Report from Children's Oncology Group AHOD0031

Rachel S. Werk et al.

Summary: This study investigates the associations between experiences and beliefs and post-traumatic stress symptoms (PTSS) among adolescent survivors of intermediate-risk Hodgkin lymphoma (HL). The results indicate that fatigue, concerns for the future, activity limitations, and relapse history are associated with higher PTSS scores. Longer time since diagnosis is associated with lower PTSS scores.

JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY (2023)

Article Nutrition & Dietetics

Vitamin E, Alpha-Tocopherol, and Its Effects on Depression and Anxiety: A Systematic Review and Meta-Analysis

Ainsley Ryan Yan Bin Lee et al.

Summary: This systematic review and meta-analysis evaluated the effects of vitamin E supplementation on depression and anxiety. The results showed that vitamin E supplementation had a beneficial effect on depression, but the effect on anxiety was inconclusive. Future studies with larger sample sizes and excluding other constituents are warranted.

NUTRIENTS (2022)

Article Psychology, Developmental

Worries and Benefit Finding in Cancer Survivors and Parents: A Longitudinal Study

Sofie Prikken et al.

Summary: This study aimed to explore the interplay between positive and negative illness experiences in childhood cancer survivors and their families, and prospectively investigate the relationship between benefit finding, cancer-related worries, depressive symptoms, and life satisfaction. The findings suggest that benefit finding is related to both positive well-being and negative illness experiences, and can buffer the negative effects of cancer-related worries on life satisfaction.

JOURNAL OF PEDIATRIC PSYCHOLOGY (2022)

Article Oncology

Health-related quality of life in long-term survivors of childhood brain tumors: a population-based cohort study

Lisa Ljungman et al.

Summary: This study investigated the health-related quality of life (HRQL) and predictors of survivors of childhood brain tumors. The results showed that male survivors had lower HRQL and depressive symptoms had a significant impact on HRQL.

SUPPORTIVE CARE IN CANCER (2022)

Review Health Care Sciences & Services

Behavioral Interventions for the Patient-Caregiver Unit in Patients with Chronic Heart Failure: A Systematic Review of Caregiver Outcomes

G. Suthershinii et al.

Summary: This systematic review examines the effectiveness of behavioral interventions targeted at chronic heart failure patients and informal caregivers. The study found limited improvement on quality of life, depression, and loneliness among caregivers.

JOURNAL OF MULTIDISCIPLINARY HEALTHCARE (2022)

Article Psychology, Clinical

Depression, anxiety and post-traumatic growth among COVID-19 survivors six-month after discharge

Xin Xiao et al.

Summary: The study investigated depression, anxiety, and post-traumatic growth (PTG) among COVID-19 survivors and their correlates. The results suggest that post-hospitalisation and psychosocial factors had relatively stronger associations with depression, anxiety, and PTG.

EUROPEAN JOURNAL OF PSYCHOTRAUMATOLOGY (2022)

Review Pharmacology & Pharmacy

Transcranial alternating current stimulation and its effects on cognition and the treatment of psychiatric disorders: a systematic review and meta-analysis

Ainsley Ryan Yan Bin Lee et al.

Summary: Transcranial alternating current stimulation (TACS) is a non-invasive method of brain stimulation that has shown promise in ameliorating symptoms of depression and schizophrenia in patients. It also improves cognition in both patients and healthy subjects. However, the findings are limited by the sample size of included studies, and further research is needed to better understand the potential of TACS.

THERAPEUTIC ADVANCES IN CHRONIC DISEASE (2022)

Article Psychiatry

Psychiatric disorders in childhood cancer survivors in Denmark, Finland, and Sweden: a register-based cohort study from the SALiCCS research programme

Line Elmerdahl Frederiksen et al.

Summary: Childhood cancer survivors have a higher long-term risk of psychiatric disorders compared to their siblings and the general population. They are more likely to have recurrent psychiatric hospital contacts and contacts for different psychiatric disorders.

LANCET PSYCHIATRY (2022)

Article Oncology

Childhood cancer: Estimating regional and global incidence

W. T. Johnston et al.

Summary: Most of the world's population is not covered by cancer surveillance systems, making estimating global childhood cancer burden more challenging. The Baseline Model estimated a higher number of childhood cancers compared to other models.

CANCER EPIDEMIOLOGY (2021)

Article Oncology

Childhood cancer: Survival, treatment modalities, late effects and improvements over time

Friederike Erdmann et al.

Summary: Pediatric oncologists have improved in organization and clinical trial participation, with chemotherapy being the main treatment element and high survival rates achieved in most European and North American countries. Survivors of childhood cancer face long-term risks of somatic and mental health issues, as well as social and economic difficulties.

CANCER EPIDEMIOLOGY (2021)

Article Clinical Neurology

Pathways to post-traumatic growth in cancer patients: moderated mediation and single mediation analyses with resilience, personality, and coping strategies

A. Gori et al.

Summary: The study found that resilience levels can directly or indirectly impact post-traumatic growth (PTG) or post-traumatic symptoms in cancer patients, with positive attitude as a mediator. Additionally, openness has a negative moderating effect on the relationship between resilience and positive attitude.

JOURNAL OF AFFECTIVE DISORDERS (2021)

Review Medicine, General & Internal

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Matthew J. Page et al.

Summary: The PRISMA statement was designed to help systematic reviewers transparently report the purpose, methods, and findings of their reviews. The updated PRISMA 2020 statement includes new reporting guidance, a 27-item checklist, an abstract checklist, and revised flow diagrams for reviews.

BMJ-BRITISH MEDICAL JOURNAL (2021)

Review Oncology

Post-traumatic growth after cancer: a scoping review of qualitative research

Fiona Menger et al.

Summary: Interest in post-traumatic growth after cancer is increasing due to its positive associations with health-related quality of life. Qualitative research provides valuable insight into survivors' experiences, with findings suggesting that positive health behavior changes may occur post-cancer and warrant further exploration in future research.

SUPPORTIVE CARE IN CANCER (2021)

Article Oncology

Trajectories and risk factors for anxiety and depression in children and adolescents with cancer: A 1-year follow-up

Maya Yardeni et al.

Summary: The study found that about half of children with cancer experienced anxiety and/or depressive disorders at least once during the follow-up period. Over time, there was a decrease in depressive symptoms and disorders, while anxiety disorders remained stable. The results highlight the importance of focusing on children with brain tumors and those in the acute phase of treatment regarding anxiety and disorders.

CANCER MEDICINE (2021)

Review Psychology, Multidisciplinary

A Meta-analytic Review of the Relationship Between Posttraumatic Growth, Anxiety, and Depression

Laura J. Long et al.

Summary: The meta-analysis found that the relationship between posttraumatic growth and global anxiety and depression is not significant, with significant heterogeneity in effects. In samples with cancer, less posttraumatic growth is more strongly associated with depression, while certain aspects of posttraumatic growth are related to greater anxiety in non-cancer samples.

JOURNAL OF HAPPINESS STUDIES (2021)

Article Psychology, Multidisciplinary

Depression, Anxiety and Post-traumatic Growth Among Bereaved Adults: A Latent Class Analysis

Jie Li et al.

Summary: The study explored the co-occurrence of depression, anxiety, and post-traumatic growth among bereaved Chinese adults and identified differential predictors of class membership. The findings highlight the important role of stressor characteristics and support in influencing impairment and positive outcomes in bereavement.

FRONTIERS IN PSYCHOLOGY (2021)

Review Medicine, General & Internal

Synthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline

Mhairi Campbell et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

Review Clinical Neurology

The prevalence of moderate-to-high posttraumatic growth: A systematic review and meta-analysis

Wu Xiaoli et al.

JOURNAL OF AFFECTIVE DISORDERS (2019)

Article Psychology, Social

Predicting social withdrawal, anxiety and depression symptoms in pediatric brain tumor survivors

Leandra Desjardins et al.

JOURNAL OF PSYCHOSOCIAL ONCOLOGY (2019)

Review Health Care Sciences & Services

The Effectiveness of Psychosocial Interventions for Psychological Outcomes in Pediatric Oncology: A Systematic Review

Anna Coughtrey et al.

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT (2018)

Article Medicine, General & Internal

A prospective follow-up of quality of life, depression, and anxiety in children with lymphoma and solid tumors

Nihal Sargin Yildirim et al.

TURKISH JOURNAL OF MEDICAL SCIENCES (2017)

Article Oncology

Survivors of Childhood Cancer in the United States: Prevalence and Burden of Morbidity

Siobhan M. Phillips et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2015)

Article Pediatrics

Psychological Morbidity in Children Undergoing Chemotherapy for Acute Lymphoblastic Leukemia

Vineeta Gupta et al.

INDIAN JOURNAL OF PEDIATRICS (2014)

Review Health Care Sciences & Services

The development of a critical appraisal tool for use in systematic reviews addressing questions of prevalence

Zachary Munn et al.

INTERNATIONAL JOURNAL OF HEALTH POLICY AND MANAGEMENT (2014)

Article Psychiatry

The Biological Effects of Childhood Trauma

Michael D. De Bellis et al.

CHILD AND ADOLESCENT PSYCHIATRIC CLINICS OF NORTH AMERICA (2014)

Article Psychiatry

Pediatric Depression: An Evidence-Based Update on Treatment Interventions

Amy H. Cheung et al.

CURRENT PSYCHIATRY REPORTS (2013)

Review Oncology

Coping processes relevant to posttraumatic growth: an evidence-based review

Rama Krsna Rajandram et al.

SUPPORTIVE CARE IN CANCER (2011)

Article Oncology

The Impact of Cancer on Children's Physical, Emotional, and Psychosocial Well-being

Ho Cheung William Li et al.

CANCER NURSING (2010)

Review Oncology

Epidemiology of childhood cancer

Peter Kaatsch

CANCER TREATMENT REVIEWS (2010)

Article Oncology

Social Outcomes in the Childhood Cancer Survivor Study Cohort

James G. Gurney et al.

JOURNAL OF CLINICAL ONCOLOGY (2009)

Article Mathematical & Computational Biology

Performance of the trim and fill method in the presence of publication bias and between-study heterogeneity

Jaime L. Peters et al.

STATISTICS IN MEDICINE (2007)

Article Medicine, General & Internal

Chronic health conditions in adult survivors of childhood cancer

Kevin C. Oeffinger et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Review Psychology, Developmental

Posttraumatic stress symptoms after childhood cancer

O Taieb et al.

EUROPEAN CHILD & ADOLESCENT PSYCHIATRY (2003)

Article Psychology, Developmental

Incidence and associations of parental and child posttraumatic stress symptoms in pediatric patients

MA Landolt et al.

JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY (2003)

Article Mathematical & Computational Biology

Quantifying heterogeneity in a meta-analysis

JPT Higgins et al.

STATISTICS IN MEDICINE (2002)