4.7 Article

Role of Chemerin and Perivascular Adipose Tissue Characteristics on Cardiovascular Risk Assessment by Arterial Stiffness Markers in Patients with Morbid Obesity

Related references

Note: Only part of the references are listed.
Review Medicine, General & Internal

Cardiac Rehabilitation in Patients with Peripheral Artery Disease-A Literature Review in COVID-19 Era

Razvan Anghel et al.

Summary: This article reviews and summarizes the scientific literature on cardiac rehabilitation programs for patients with peripheral artery disease (PAD) and explores how these programs were adapted during the COVID-19 pandemic. The implementation of such programs has faced challenges due to social distancing and work-related restrictions. Home-based walking exercises and alternative forms of exercise such as cycling have been found to be more accessible and acceptable during the pandemic. Supervised exercise therapy has shown positive impacts on functional capacity and quality of life for these patients.

JOURNAL OF CLINICAL MEDICINE (2022)

Review Biochemistry & Molecular Biology

Novel Biomarkers of Atherosclerotic Vascular Disease-Latest Insights in the Research Field

Cristina Andreea Adam et al.

Summary: Atherosclerotic vascular disease is a cardiovascular continuum that has led to the development of new diagnostic and therapeutic strategies. The understanding of pathophysiological mechanisms and molecules involved in atherosclerosis has resulted in the identification of potential new biomarkers for early diagnosis. Technological advancements have shifted the focus to new biomarkers for future therapeutic targets.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Nutrition & Dietetics

Relationship between adipose tissue distribution and arterial stiffness in HFpEF

Weiwei Hu et al.

Summary: The study aimed to investigate the relationship between adipose tissue distribution and arterial stiffness in patients with heart failure and preserved ejection fraction. Results showed a significant correlation between VFA and baPWV, with VFA independently associated with baPWV.

NUTRITION (2022)

Article Pharmacology & Pharmacy

Perivascular adipose tissue-mediated arterial stiffening in aging and disease: An emerging translational therapeutic target?

Bradley S. Fleenor et al.

Summary: Cardiovascular diseases are the leading cause of death in modern societies, and arterial stiffening plays a crucial role in the development of these diseases. Perivascular adipose tissue, a relatively understudied fat depot, has direct and profound effects on arterial stiffening. Identifying it as a therapeutic target to lower arterial stiffness and reduce cardiovascular disease risk has significant clinical implications.

PHARMACOLOGICAL RESEARCH (2022)

Article Biology

Cardiac Rehabilitation in Peripheral Artery Disease in a Tertiary Center-Impact on Arterial Stiffness and Functional Status after 6 Months

Razvan Anghel et al.

Summary: This study assessed factors associated with clinical improvement in patients with peripheral artery disease (PAD) undergoing a rehabilitation program at an academic medical center in north-eastern Europe. The results showed that smoking cessation, changing sedentary lifestyle, and improvement in lipid and carbohydrate profile, as well as functional status parameters, were associated with clinical improvement at the 6-months follow-up. This study highlights the importance of an integrative, multidisciplinary management approach in maintaining functional status and improving quality of life in PAD patients.

LIFE-BASEL (2022)

Review Biology

Impact of Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors on Arterial Stiffness and Vascular Aging-What Do We Know So Far? (A Narrative Review)

Cristina Andreea Adam et al.

Summary: Vascular aging is closely related to the occurrence of cardiovascular diseases. Sodium-glucose cotransporter 2 inhibitors can reduce arterial stiffness and vascular resistance, improve endothelial function, and decrease the risk of cardiovascular events.

LIFE-BASEL (2022)

Review Biochemistry & Molecular Biology

The Role of Adipokines in Inflammatory Mechanisms of Obesity

Tatiana V. V. Kirichenko et al.

Summary: This article reviews the key functions of adipokines in the inflammatory mechanisms, complications, and associated diseases of obesity. Through an extensive search on the role of adipokines in the pathogenesis of obesity, existing research findings are summarized.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Review Biochemistry & Molecular Biology

Role of Chemerin in Cardiovascular Diseases

Mirjana T. Macvanin et al.

Summary: This review summarizes the latest research findings on the mechanisms of chemerin action, its role in the development and progression of cardiovascular diseases, and novel strategies for developing chemerin-targeting therapeutic agents.

BIOMEDICINES (2022)

Article Medicine, General & Internal

Cardiac Rehabilitation and Mortality Risk Reduction in Peripheral Artery Disease at 6-Month Outcome

Razvan Anghel et al.

Summary: The management of patients with peripheral artery disease (PAD) is integrative and multidisciplinary, in which cardiac rehabilitation (CR) plays a prognostic role in terms of functional status, quality of life, and long-term impact on morbidity and mortality. This study found that comorbidities such as obesity, renal dysfunction, dyslipidemia, tobacco use, and diabetes mellitus have long-term prognostic value for PAD patients. Additionally, factors such as low-density lipoprotein cholesterol, triglycerides, fasting glucose, peak oxygen uptake, pain-free walking distance, maximum walking time, and maximum walking distance are associated with clinical improvement at the 6-month follow-up for PAD patients.

DIAGNOSTICS (2022)

Article Cardiac & Cardiovascular Systems

Prognostic value of plasma adipokine chemerin in patients with coronary artery disease

Bo Wang et al.

Summary: This study found that plasma chemerin levels were increased in CAD patients, and high chemerin levels were an independent predictor of MACEs in CAD patients.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

Editorial Material Biochemistry & Molecular Biology

Metabolic Syndrome: From Molecular Mechanisms to Novel Therapies

Ali Abbas Rizvi et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Nutrition & Dietetics

Visceral adiposity index is associated with arterial stiffness in hypertensive adults with normal-weight: the china H-type hypertension registry study

Junpei Li et al.

Summary: The study found a positive association between VAI and baPWV as well as high arterial stiffness in normal-weight adults with hypertension. Establishing this association could aid in stratifying arterial stiffness risk in normal-weight hypertensive populations, who are often overlooked in cardiovascular disease prevention.

NUTRITION & METABOLISM (2021)

Article Multidisciplinary Sciences

Association between body fat parameters and arterial stiffness

Hack-Lyoung Kim et al.

Summary: This study found that baPWV was associated with WHR and VFA, but not with BMI and WC. This suggests that arterial stiffness may have a stronger connection to abdominal obesity than overall obesity.

SCIENTIFIC REPORTS (2021)

Article Cardiac & Cardiovascular Systems

Comparison Between Invasive and Noninvasive Methods to Estimate Subendocardial Oxygen Supply and Demand Imbalance

Paolo Salvi et al.

Summary: Carotid applanation tonometry is a valid noninvasive method for estimating SEVR values when all factors determining myocardial supply and demand flow are taken into consideration. The new noninvasive method showed much better agreement with invasive determination of SEVR compared to the traditional method.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2021)

Review Medicine, General & Internal

Adipokines and Arterial Stiffness in Obesity

Ioana Para et al.

Summary: Adipokines are active molecules produced by adipose tissue involved in obesity-related metabolic and cardiovascular diseases. Arterial stiffness, a consequence of arteriosclerosis, is an independent predictor of cardiovascular morbidity and mortality. Dysregulation of adipokines may lead to increased arterial stiffness through various mechanisms.

MEDICINA-LITHUANIA (2021)

Article Physiology

Measures of ejection duration and subendocardial viability ratio in normal weight and overweight adolescent children

Nicholas D. Tocci et al.

Summary: The study found that overweight adolescents demonstrated higher values in cf-PWV and ASBP, as well as lower values in SEVR compared to their normal weight peers.

PHYSIOLOGICAL REPORTS (2021)

Article Biochemistry & Molecular Biology

Exercise training prevents the perivascular adipose tissue-induced aortic dysfunction with metabolic syndrome

Evan DeVallance et al.

REDOX BIOLOGY (2019)

Article Medicine, Research & Experimental

Assessment of Arterial Stiffness in Metabolic Syndrome Related to Insulin Resistance in Apparently Healthy Men

Ali Reza Khoshdel et al.

METABOLIC SYNDROME AND RELATED DISORDERS (2019)

Review Physiology

Cellular mechanisms underlying obesity-induced arterial stiffness

Annayya R. Aroor et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2018)

Review Endocrinology & Metabolism

Chemerin: a multifaceted adipokine involved in metabolic disorders

Gisela Helfer et al.

JOURNAL OF ENDOCRINOLOGY (2018)

Article Peripheral Vascular Disease

Long-Term Improvement in Aortic Pulse Wave Velocity After Weight Loss Can Be Predicted by White Adipose Tissue Factors

Jesper Backdahl et al.

AMERICAN JOURNAL OF HYPERTENSION (2018)

Article Geriatrics & Gerontology

Hesperidin reverses perivascular adipose-mediated aortic stiffness with aging

An Ouyang et al.

EXPERIMENTAL GERONTOLOGY (2017)

Review Pharmacology & Pharmacy

Perivascular adipose tissue inflammation in vascular disease

Ryszard Nosalski et al.

BRITISH JOURNAL OF PHARMACOLOGY (2017)

Review Cardiac & Cardiovascular Systems

Metabolic syndrome: pathophysiology, management, and modulation by natural compounds

Yogita Rochlani et al.

THERAPEUTIC ADVANCES IN CARDIOVASCULAR DISEASE (2017)

Article Cardiac & Cardiovascular Systems

Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease

Jose J. Fuster et al.

CIRCULATION RESEARCH (2016)

Review Endocrinology & Metabolism

Perivascular adipose tissue: An unique fat compartment relevant for the cardiometabolic syndrome

D. I. Siegel-Axel et al.

REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2016)

Review Endocrinology & Metabolism

Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism

Amaia Rodriguez et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2015)

Review Peripheral Vascular Disease

An update on the role of adipokines in arterial stiffness and hypertension

Andrea R. Sabbatini et al.

JOURNAL OF HYPERTENSION (2015)

Review Hematology

Adipokines at the crossroad between obesity and cardiovascular disease

Filippo Molica et al.

THROMBOSIS AND HAEMOSTASIS (2015)

Review Physiology

Vascular stiffness in insulin resistance and obesity

Guanghong Jia et al.

FRONTIERS IN PHYSIOLOGY (2015)

Article Cardiac & Cardiovascular Systems

Adiponectin, type 2 diabetes and cardiovascular risk

Soren Lindberg et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2015)

Article Hematology

Links Between Ectopic Fat and Vascular Disease in Humans

Soo Lim et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2014)

Article Hematology

Perivascular Adipose Tissue in Vascular Function and Disease A Review of Current Research and Animal Models

Nicholas K. Brown et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2014)

Review Biochemistry & Molecular Biology

Processing, Signaling, and Physiological Function of Chemerin

Andreas Mattern et al.

IUBMB LIFE (2014)

Review Cardiac & Cardiovascular Systems

Adipokines: A link between obesity and cardiovascular disease

Kazuto Nakamura et al.

JOURNAL OF CARDIOLOGY (2014)

Review Medicine, Research & Experimental

Adipokines and Lipoproteins: Modulation by Antihyperglycemic and Hypolipidemic Agents

Ali A. Rizvi et al.

METABOLIC SYNDROME AND RELATED DISORDERS (2014)

Article Cardiac & Cardiovascular Systems

The Myocardial Oxygen Supply: Demand Index Revisited

Julien I. E. Hoffman et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2014)

Review Endocrinology & Metabolism

Adipokines as a novel link between obesity and atherosclerosis

Hye Jin Yoo et al.

WORLD JOURNAL OF DIABETES (2014)

Review Pathology

Biological Relevance of Inflammation and Oxidative Stress in the Pathogenesis of Arterial Diseases

David P. Hajjar et al.

AMERICAN JOURNAL OF PATHOLOGY (2013)

Review Cardiac & Cardiovascular Systems

Adipokines as mediators of endothelial function and atherosclerosis

George Ntaios et al.

ATHEROSCLEROSIS (2013)

Article Cardiac & Cardiovascular Systems

Adiponectin and progression of arterial stiffness in hypertensive patients

Jong-Chan Youn et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2013)

Review Endocrinology & Metabolism

Towards an integrative approach to understanding the role of chemerin in human health and disease

J. L. Rourke et al.

OBESITY REVIEWS (2013)

Article Peripheral Vascular Disease

Circulating Chemerin Level is Independently Correlated with Arterial Stiffness

Hye Jin Yoo et al.

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2012)

Review Endocrinology & Metabolism

Obesidomics: contribution of adipose tissue secretome analysis to obesity research

Maria Pardo et al.

ENDOCRINE (2012)

Article Endocrinology & Metabolism

Adipose tissue mass and location affect circulating adiponectin levels

A. T. Turer et al.

DIABETOLOGIA (2011)

Article Peripheral Vascular Disease

Adipokines in Periaortic and Epicardial Adipose Tissue: Differential Expression and Relation to Atherosclerosis

Sofia G. Spiroglou et al.

Journal of Atherosclerosis and Thrombosis (2011)

Review Immunology

Adipokines in inflammation and metabolic disease

Noriyuki Ouchi et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Review Cell Biology

The autocrine and paracrine roles of adipokines

Kalypso Karastergiou et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)

Review Cell Biology

Adipose tissue as an endocrine organ

Sandra Galic et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)

Article Biochemistry & Molecular Biology

Secretory Products From Human Adipocytes Stimulate Proinflammatory Cytokine Secretion From Human Endothelial Cells

Grit Sommer et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

Toshimasa Yamauchi et al.

NATURE MEDICINE (2007)

Review Cardiac & Cardiovascular Systems

Cardioprotection by adiponectin

Noriyuki Ouchi et al.

TRENDS IN CARDIOVASCULAR MEDICINE (2006)

Article Cardiac & Cardiovascular Systems

Mature adipocytes and perivascular adipose tissue stimulate vascular smooth muscle cell proliferation: effects of aging and obesity

C Barandier et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)