4.4 Article

Microwave-Assisted PEG-400 Medaited Synthesis of 4,5-dihydro-1H-benzo[g]indazole Derivatives: An Enaminone Approach

Related references

Note: Only part of the references are listed.
Review Chemistry, Applied

Recent Advances in Reactions Using Enaminone in Water or Aqueous Medium

Zhouying Wang et al.

Summary: Enaminones have attracted renewed interest in organic synthesis for their versatility, especially their ability to tolerate water. Designing synthetic methods in aqueous medium using enaminones as building blocks has received extensive attention and notable success.

ADVANCED SYNTHESIS & CATALYSIS (2022)

Article Chemistry, Multidisciplinary

Iron-catalyzed [4

Jindian Duan et al.

Summary: The iron-catalyzed [4 + 2] annulation reaction of α, β-unsaturated ketoxime acetates with enaminones has been developed, providing efficient access to highly substituted pyridines in moderate to good yields. Notable features of this strategy include low-cost catalytic system, simple and mild reaction condition, and wide substrate scope. Mechanistic studies suggest that FeCl2 may directly serve as a Lewis acid to activate the α, β-unsaturated ketoxime acetates for the nucleophilic addition.

GREEN SYNTHESIS AND CATALYSIS (2021)

Review Oncology

2-Pyrazolines as Biologically Active and Fluorescent Agents, An Overview

Pramod Singh et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2018)

Article Chemistry, Multidisciplinary

A General One-Pot Synthesis of 2H-Indazoles Using an Organophosphorus-Silane System

Jens Schoene et al.

CHEMISTRY-A EUROPEAN JOURNAL (2018)

Article Chemistry, Multidisciplinary

Synthesis and in vitro Antifungal Evaluation of Novel N-Substituted 4-Aryl-2-methylimidazoles

Nerith-Rocio Elejalde et al.

CHEMISTRYSELECT (2018)

Review Chemistry, Medicinal

Synthesis of indazole motifs and their medicinal importance: An overview

Digambar D. Gaikwad et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)

Article Chemistry, Organic

Variations in the Blaise Reaction: Conceptually New Synthesis of 3-Amino Enones and 1,3-Diketones

H. Surya Prakash Rao et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2015)

Article Chemistry, Medicinal

Indazole- and Indole-5-carboxamides: Selective and Reversible Monoamine Oxidase B Inhibitors with Subnanomolar Potency

Nikolay T. Tzvetkov et al.

JOURNAL OF MEDICINAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

Enaminones 11. An examination of some ethyl ester enaminone derivatives as anticonvulsant agents

Mariano S. Alexander et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors

Keith W. Woods et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2006)

Article Chemistry, Organic

Total synthesis of nigellicine and nigeglanine hydrobromide

EL Elliott et al.

ORGANIC LETTERS (2005)

Review Chemistry, Multidisciplinary

Polyethylene glycol and solutions of polyethylene glycol as green reaction media

J Chen et al.

GREEN CHEMISTRY (2005)

Article Infectious Diseases

Evaluation of in vitro and in vivo activity of benzindazole-4,9-quinones against Cryptosporidium parvum

O Kayser et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2002)

Article Biochemical Research Methods

Structure-based design of inhibitors of the rice blast fungal enzyme trihydroxynaphthalene reductase

DB Jordan et al.

JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2001)