Fucoxanthin as antioxidant, anti-hyaluronidase and cytotoxic agent: potential of brown seaweeds decoction for tea supplement

The decoctions of Dictyota dichotoma, Padina gymnospora, Sargassum wightii, Turbinaria conoides, tea leaf (Camellia sinensis), and commercial tea were prepared separately. The antioxidant, anti-hyaluronidase (anti-wrinkling) and cytotoxic activities of decoctions were assessed. The decoctions were added with milk tea and assessed their physio-palatable property. The results showed that among the four seaweed decoctions (BSDs), Dictyota dichotoma exhibits a remarkable antioxidant, anti-hyaluronidase and cytotoxic properties. The decoctions of tea leaf, Dictyota dichotoma, Padina gymnospora, Turbinaria conoides and Sargassum wightii had the cytotoxic property with -IC50 of 64.68, 73.24, 161.35, 203.52, 218.73 mu g/ml, respectively against HeLa cell lines. The FTIR of the BSD confirmed the presence of fucoxanthin as the principal compound. After adding milk, the mixture of decoctions prepared by tea and brown seaweeds the pH was increased from 4.97 (commercial tea) to 6.93 (Dictyota dichotoma) that would protect teeth from correction caused by acidic tea decoction besides other health benefits. Hence, it can be used as a healthy and nutritious tea drink to protect the skin from solar radiation as values addition to tea. [GRAPHICS] .

Automated summary

Different plant and seaweed decoctions were evaluated, and it was found that Dictyota dichotoma, Padina gymnospora, Sargassum wightii, and tea leaf showed excellent antioxidant, anti-hyaluronidase, and cytotoxic effects. Among them, Dictyota dichotoma exhibited the strongest cytotoxicity against Hela cells. After adding milk, the pH of the mixture of tea and brown seaweeds increased from 4.97 (commercial tea) to 6.93 (Dictyota dichotoma), providing protection for teeth against acidic tea decoctions and offering additional health benefits for skin protection against solar radiation.