Current opinions on the present and future use of functional near-infrared spectroscopy in psychiatry

Functional near-infrared spectroscopy (fNIRS) is an optical imaging technique for assessing human brain activity by noninvasively measuring the fluctuation of cerebral oxygenated- and deoxygenated-hemoglobin concentrations associated with neuronal activity. Owing to its superior mobility, low cost, and good tolerance for motion, the past few decades have witnessed a rapid increase in the research and clinical use of fNIRS in a variety of psychiatric disorders. In this perspective article, we first briefly summarize the state-of-the-art concerning fNIRS research in psychiatry. In particular, we highlight the diverse applications of fNIRS in psychiatric research, the advanced development of fNIRS instruments, and novel fNIRS study designs for exploring brain activity associated with psychiatric disorders. We then discuss some of the open challenges and share our perspectives on the future of fNIRS in psychiatric research and clinical practice. We conclude that fNIRS holds promise for becoming a useful tool in clinical psychiatric settings with respect to developing closed-loop systems and improving individualized treatments and diagnostics. (c) The Authors. Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

Automated summary

Functional near-infrared spectroscopy (fNIRS) is a noninvasive optical imaging technique used to assess human brain activity. It has been widely used in psychiatric research and clinical practice due to its mobility, low cost, and tolerance for motion. This article summarizes the applications of fNIRS in psychiatry, the development of fNIRS instruments, and new study designs to explore brain activity associated with psychiatric disorders. The challenges and future perspectives of fNIRS in psychiatric research and clinical practice are also discussed.