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Article
Biochemistry & Molecular Biology
Treatment resistance in psychiatry: state of the art and new directions
Oliver D. Howes et al.
Summary: Treatment resistance is a common issue in psychiatric disorders, leading to increased healthcare burden and costs. Despite growing research attention, there are significant gaps in understanding and addressing this issue, with key outstanding problems including heterogeneity and lack of consensus criteria. Recommendations for future research include harmonisation of definitions and exploration of novel interventions to improve targeted and personalised therapeutic approaches.
MOLECULAR PSYCHIATRY (2022)