Review: Research progress of adipose-derived stem cells in the treatment of chronic wounds

Although methods are used to treat wounds clinically, there are still many challenges in the treatment of chronic wounds due to excessive inflammatory response, difficulties in epithelialization, vascularization, and other factors. With the increasing research on adipose-derived stem cells (ADSCs) in recent years, accumulating evidence has shown that ADSCs scan promotes the healing of chronic wounds by regulating macrophage function and cellular immunity and promoting angiogenesis and epithelialization. The present study reviewed the difficulties in the treatment of chronic wounds, as well as the advantages and the mechanism of ADSCs in promoting the healing of chronic wounds, to provide a reference for the stem cell therapy of chronic wounds.

Automated summary

Although there are methods for treating wounds clinically, chronic wounds still pose challenges due to excessive inflammation, difficulties in epithelialization, vascularization, and other factors. Recent research on adipose-derived stem cells (ADSCs) has shown that they can promote the healing of chronic wounds by regulating macrophage function, cellular immunity, and promoting angiogenesis and epithelialization. This study reviews the difficulties in treating chronic wounds and the advantages and mechanisms of ADSCs in promoting their healing to provide a reference for stem cell therapy.