4.7 Article

Glutaredoxin 1 protects lens epithelial cells from epithelial-mesenchymal transition by preventing casein kinase 1? S-glutathionylation during posterior capsular opacification

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Glutaredoxin 1 controls monocyte reprogramming during nutrient stress and protects mice against obesity and atherosclerosis in a sex-specific manner

Yong Joo Ahn et al.

Summary: High-calorie diet leads to the reprogramming of blood monocytes and the formation of adipocytes, while the absence of enzyme glutaredoxin 1 in female mice causes abnormal oxidative stress responses in macrophages, promoting atherogenesis and obesity.

NATURE COMMUNICATIONS (2022)

Review Biochemistry & Molecular Biology

Glutathione and Glutaredoxin in Redox Regulation and Cell Signaling of the Lens

Marjorie F. Lou

Summary: The ocular lens contains high levels of the antioxidants glutathione and thioltransferase, which play important roles in regulating redox balance and protecting the lens from oxidative damage.

ANTIOXIDANTS (2022)

Article Cell Biology

Moderate oxidative stress promotes epithelial-mesenchymal transition in the lens epithelial cells via the TGF-β/Smad and Wnt/β-catenin pathways

Xi Chen et al.

Summary: The study demonstrates that both TGF-beta/Smad and canonical Wnt/beta-catenin pathways play a significant role in regulating epithelial-mesenchymal transformation of lens epithelial cells but might be in a different stage.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2021)

Article Multidisciplinary Sciences

Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages

Yuxian Guo et al.

Summary: Redox-dependent regulation plays a key role in the pathogenesis of acute lung injury, and the study demonstrates that Grx1-regulated S-glutathionylation controls macrophage inflammation and alleviates acute lung injury, revealing a molecular mechanism.

NATURE COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

Glutaredoxin: Discovery, redox defense and much more

Fernando T. Ogata et al.

Summary: Glutaredoxin (Grx) is a small protein with an active site cysteine pair that regulates redox reactions through glutathionylation, playing a crucial role in various physiological and pathological conditions.

REDOX BIOLOGY (2021)

Review Medicine, General & Internal

Posterior Capsule Opacification: A Review of Experimental Studies

Joanna Konopinska et al.

Summary: Posterior capsule opacification (PCO) is a common complication of cataract surgery, with an incidence of up to 10%. Research focuses on the pathomechanism, prevention methods, and in vitro studies, while clinical studies and pharmacological methods are also being explored. Further studies are needed to understand the multifactorial etiology and variations in responses to surgery in humans and laboratory animals.

JOURNAL OF CLINICAL MEDICINE (2021)

Review Biochemistry & Molecular Biology

Sexual dimorphism in glutathione metabolism and glutathione-dependent responses

Luxi Wang et al.

REDOX BIOLOGY (2020)

Article Biochemistry & Molecular Biology

MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling

Qingling Huang et al.

EMBO JOURNAL (2020)

Review Biochemistry & Molecular Biology

Role of Glutaredoxin-1 and Glutathionylation in Cardiovascular Diseases

Mannix Burns et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Biochemistry & Molecular Biology

-Catenin/Smad3 Interaction Regulates Transforming Growth Factor--Induced Epithelial to Mesenchymal Transition in the Lens

Aftab Taiyab et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Biochemistry & Molecular Biology

Glutaredoxin1 Diminishes Amyloid Beta-Mediated Oxidation of F-Actin and Reverses Cognitive Deficits in an Alzheimer's Disease Mouse Model

Reddy Peera Kommaddi et al.

ANTIOXIDANTS & REDOX SIGNALING (2019)

Review Cell Biology

Casein kinase 1α: biological mechanisms and theranostic potential

Shaojie Jiang et al.

CELL COMMUNICATION AND SIGNALING (2018)

Article Biochemistry & Molecular Biology

S-Glutathionylation of estrogen receptor α affects dendritic cell function

Jie Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Article Biochemical Research Methods

Glutaredoxin-1 Silencing Induces Cell Senescence via p53/p21/p16 Signaling Axis

Fan Yang et al.

JOURNAL OF PROTEOME RESEARCH (2018)

Article Biochemistry & Molecular Biology

Reducing protein oxidation reverses lung fibrosis

Vikas Anathy et al.

NATURE MEDICINE (2018)

Review Biochemistry & Molecular Biology

Roles of TGF β and FGF Signals in the Lens: Tropomyosin Regulation for Posterior Capsule Opacity

Eri Kubo et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Ophthalmology

Lens Epithelial Cells Initiate an Inflammatory Response Following Cataract Surgery

Jian Jiang et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2018)

Review Medicine, General & Internal

Cataracts

Yu-Chi Liu et al.

LANCET (2017)

Article Biochemistry & Molecular Biology

Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1

Di Shao et al.

ANTIOXIDANTS & REDOX SIGNALING (2017)

Article Cell Biology

MiR-9-5p promotes MSC migration by activating β-catenin signaling pathway

Xianyang Li et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2017)

Review Ophthalmology

The global state of cataract blindness

Cameron M. Lee et al.

CURRENT OPINION IN OPHTHALMOLOGY (2017)

Review Toxicology

Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases

Olga Gorelenkova Miller et al.

ARCHIVES OF TOXICOLOGY (2015)

Article Multidisciplinary Sciences

Lenalidomide induces ubiquitination and degradation of CK1a in del(5q) MDS

Jan Kroenke et al.

NATURE (2015)

Review Ophthalmology

Posterior Capsule Opacification After Phacoemulsification: Annual Review

Abhay R. Vasavada et al.

ASIA-PACIFIC JOURNAL OF OPHTHALMOLOGY (2014)

Article Multidisciplinary Sciences

RNA Helicase DDX3 Is a Regulatory Subunit of Casein Kinase 1 in Wnt-β-Catenin Signaling

Cristina-Maria Cruciat et al.

SCIENCE (2013)

Article Ophthalmology

TGFβ/Smad4-Dependent and -Independent Regulation of Human Lens Epithelial Cells

Lucy Jean Dawes et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)

Article Multidisciplinary Sciences

Phosphoproteome analysis of the human mitotic spindle

M Nousiainen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Ophthalmology

Long-term changes in the morphology of posterior capsule opacification

T Neumayer et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2005)

Article Ophthalmology

Short-term changes in the morphology of posterior capsule opacification

W Buehl et al.

JOURNAL OF CATARACT AND REFRACTIVE SURGERY (2005)

Article Ophthalmology

Posterior capsule opacification in mice

N Lois et al.

ARCHIVES OF OPHTHALMOLOGY (2005)

Article Biochemistry & Molecular Biology

Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism

CM Liu et al.

Article Ophthalmology

Glutathione: A vital lens antioxidant

FJ Giblin

JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2000)