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Implant Materials for Anterior Column Reconstruction of Cervical Spine Tumor

Journal

ORTHOPAEDIC SURGERY
Volume 15, Issue 5, Pages 1219-1227

Publisher

WILEY
DOI: 10.1111/os.13702

Keywords

3D-printed; Allogenic bone; Autogenous bone; Bioactive ceramics; Bone cement; Cervical spine reconstruction; Cervical spine tumor; Implant materials; PEEK; TMC

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The spine is commonly affected by bone metastases in cancer patients, often leading to symptomatic epidural spinal cord compression. The main treatment for cervical spine tumors is surgical resection followed by radiotherapy. Implant materials used for anterior column reconstruction in cervical spine tumor resection need to possess various properties such as biocompatibility, bioactivity, and long-term mechanical strength. The choice of implant materials plays a role in surgical efficacy and patient prognosis. This article provides an overview of different implant materials used for anterior column reconstruction, discussing their properties, advantages, disadvantages, derivatives, and clinical applications, while also looking towards future advancements in this field.
The spine is the most common site of bone metastases. Many cancer patients will ultimately develop spinal metastatic disease with symptomatic epidural spinal cord compression. At present, the main treatment for cervical spine tumors is surgical resection combined with postoperative radiotherapy. Implant materials for cervical spine anterior column reconstruction need to meet amounts of different properties, such as biocompatibility, bioactivity and the ability to maintain long-term mechanical strength. The selection of different materials determines the surgical efficacy and prognosis of patients to a certain extent. This article provides an overview of a variety of implant materials used for anterior column reconstruction after cervical spine tumor resection, introduces and analyzes their properties, advantages, disadvantages, derivatives, and applications in clinical practice, and looks forward to the future development of implant materials.

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