Journal
LANGMUIR
Volume 32, Issue 48, Pages 12710-12715Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.langmuir.6b02519
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Funding
- Singapore government's National Research Foundation [NRF-CRP9-2011-04]
- Agency of Science, Technology and Research in Singapore
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The widespread application of surface-attached nano bubbles and nanodroplets in biomedical engineering and nanotechnology is limited by numerous experimental challenges, in particular, the possibility of contamination in nucleation experiments. These challenges are complicated by recent reports that it can be difficult to distinguish between nanoscale drops and bubbles. Here we identify clear differences in the mechanical responses of nanobubbles and nanodroplets under various modes of AFM imaging that subject the objects to predominantly vertical or lateral forces. This allows us to distinguish among nanodroplets, nanobubbles, and oil-covered nanobubbles in water.
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