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A story of the potential effect of non-steroidal anti-inflammatory drugs (NSAIDs) in Parkinson's disease: beneficial or detrimental effects

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Aspirin Use Associated With Amyotrophic Lateral Sclerosis: a Total Population-Based Case-Control Study

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JOURNAL OF EPIDEMIOLOGY (2015)

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LANCET NEUROLOGY (2015)

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Non-steroidal anti-inflammatory drugs (NSAIDs) and neuroprotection in the elderly: a view from the mitochondria

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NEURAL REGENERATION RESEARCH (2015)

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DOPAMINE MIDBRAIN NEURONS IN HEALTH AND PARKINSON'S DISEASE: EMERGING ROLES OF VOLTAGE-GATED CALCIUM CHANNELS AND ATP-SENSITIVE POTASSIUM CHANNELS

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PPARγ and PGC-1α as Therapeutic Targets in Parkinson's

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Elevated prostacyclin biosynthesis in mice impacts memory and anxiety-like behavior

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BEHAVIOURAL BRAIN RESEARCH (2014)

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LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?

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Tolfenamic acid downregulates BACE1 and protects against lead-induced upregulation of Alzheimer's disease related biomarkers

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NEUROPHARMACOLOGY (2014)

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A Case-Control Study of the Protective Effect of Alcohol, Coffee, and Cigarette Consumption on Parkinson Disease Risk: Time-Since-Cessation Modifies the Effect of Tobacco Smoking

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PLOS ONE (2014)

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The T-type calcium channel as a new therapeutic target for Parkinson's disease

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COX-2-derived endocannabinoid metabolites as novel inflammatory mediators

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Origins and impact of the term 'NSAID'

Jonas Kure Buer

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The anti-inflammatory drug celecoxib inhibits t-type Ca2+ currents in spermatogenic cells yet it elicits the acrosome reaction in mature sperm

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Microsomal prostaglandin E synthase-1 is induced in alzheimer's disease and its deletion mitigates alzheimer's disease-like pathology in a mouse model

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Short-term treatment with tolfenamic acid improves cognitive functions in Alzheimer's disease mice

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NEUROBIOLOGY OF AGING (2013)

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Enhanced Prostacyclin Synthesis by Adenoviral Gene Transfer Reduced Glial Activation and Ameliorated Dopaminergic Dysfunction in Hemiparkinsonian Rats

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ACS CHEMICAL NEUROSCIENCE (2012)

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Non-steroidal anti-inflammatory drugs and amyotrophic lateral sclerosis: Results from five prospective cohort studies

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AMYOTROPHIC LATERAL SCLEROSIS (2012)

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Vascular effects of prostacyclin: does activation of PPARδ play a role?

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Non-Steroidal Anti-Inflammatory Drug Use and the Risk of Parkinson's Disease

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Association of Cumulative Lead Exposure with Parkinson's Disease

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Systemic inflammatory cells fight off neurodegenerative disease

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Anti-inflammatory drugs and risk of Parkinson disease A meta-analysis

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NEUROLOGY (2010)

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NSAID Use and the Risk of Parkinson's Disease Systematic Review and Meta-Analysis of Observational Studies

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DRUGS & AGING (2009)

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Acetaminophen inhibits neuronal inflammation and protects neurons from oxidative stress

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The translational therapeutics of prostaglandin inhibition in atherothrombosis

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Diclofenac, a Non-steroidal Anti-inflammatory Drug, Inhibits L-type Ca2+ Channels in Neonatal Rat Ventricular Cardiomyocytes

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Racial Differences in the Diagnosis of Parkinson's Disease

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Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein

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NEURON (2009)

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Therapeutic targets in prostaglandin E2 signaling for neurologic disease

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CURRENT MEDICINAL CHEMISTRY (2008)

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The endocannabinoid system in Parkinson's disease

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Non-steroidal anti-inflammatory drug use and the risk of Parkinson disease: A retrospective cohort study

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PPAR: a therapeutic target in Parkinson's disease

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Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2

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The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective

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Combined effects of smoking, coffee, and NSAIDs on Parkinson's disease risk

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Protective effects of NSAIDs on the development of Alzheimer disease

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NEUROSCIENCE LETTERS (2008)

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Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease

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PGE2 receptor EP1 renders dopaminergic neurons selectively vulnerable to low-level oxidative stress and direct PGE2 neurotoxicity

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JOURNAL OF NEUROSCIENCE RESEARCH (2007)

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Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin

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EUROPEAN JOURNAL OF PHARMACOLOGY (2007)

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Non-steroidal anti-inflammatory drugs in Parkinson's disease

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Effect of non-steroidal anti-inflammatory medications on the risk of amyotrophic lateral sclerosis

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AMYOTROPHIC LATERAL SCLEROSIS (2007)

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Prostaglandin E2 produced by late induced COX-2 stimulates hippocampal neuron loss after seizure in the CA3 region

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Aspirin protects striatal dopaminergic neurons from neurotoxin-induced degeneration: An in vivo microdialysis study

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Nonsteroidal anti-inflammatory drugs and the incidence of Parkinson disease

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NSAID Use and the Risk of Parkinson's Disease

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To be or not to be (inflamed) - is that the question in anti-inflammatory drug therapy of neurodegenerative disorders?

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Lipid signaling: Sleep, synaptic plasticity, and neuroprotection

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Dopaminergic neurotoxicity by 6-OHDA and MPP+:: Differential requirement for neuronal cyclooxygenase activity

E Carrasco et al.

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Are men at greater risk for Parkinson's disease than women?

GF Wooten et al.

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Cyclooxygenases mRNA and protein expression in striata in the experimental mouse model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration to mouse

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BRAIN RESEARCH (2004)

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Amyloid β protein impairs motor function via thromboxane A2 in the rat striatum

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NEUROBIOLOGY OF DISEASE (2004)

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Cyclooxygenase enzymes: Regulation and function

FA Fitzpatrick

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BRAIN RESEARCH BULLETIN (2003)

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Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease

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Levodopa treatment reverses endocannabinoid system abnormalities in experimental parkinsonism

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Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

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Parkinson disease with old-age onset - A comparative study with subjects with middle-age onset

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ARCHIVES OF NEUROLOGY (2003)

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Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats

K Sairam et al.

BRAIN RESEARCH (2003)

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A role for endocannabinoids in indomethacin-induced spinal antinociception

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EUROPEAN JOURNAL OF PHARMACOLOGY (2002)

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Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1,2,3,6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra

ZH Feng et al.

NEUROSCIENCE LETTERS (2002)

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Indomethacin protects against neurodegeneration caused by MPTP intoxication in mice

I Kurkowska-Jastrzebska et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2002)

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Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and-2

C Knott et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2000)

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NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: The role of oxidant/antioxidant balance

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Meta-analysis of observational studies in epidemiology - A proposal for reporting

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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)

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