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V Kumar
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V Kumar
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TRENDS IN IMMUNOLOGY (2018)
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JOURNAL OF IMMUNOLOGY (2018)
Metabolic and Transcriptional Modules Independently Diversify Plasma Cell Lifespan and Function
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MOLECULAR CANCER (2018)
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NATURE IMMUNOLOGY (2018)
Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation
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FRONTIERS IN IMMUNOLOGY (2018)
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TRENDS IN CANCER (2018)
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FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2018)
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IMMUNITY (2017)
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Amy J. Petty et al.
IMMUNOTHERAPY (2017)
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AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance
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Alberto Mantovani et al.
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IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease
Ivy M. Dambuza et al.
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FRONTIERS IN IMMUNOLOGY (2017)
Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells
Amir A. Al-Khami et al.
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NATURE IMMUNOLOGY (2017)
MYC and HIF in shaping immune response and immune metabolism
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CELL (2017)
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Julia Jellusova et al.
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Luke A. J. O'Neill et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
PD-1 expression on dendritic cells suppresses CD8(+) T cell function and antitumor immunity
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ONCOIMMUNOLOGY (2016)
Transcriptional Control of Dendritic Cell Development
Theresa L. Murphy et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 34 (2016)
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Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche
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CELL (2016)
L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
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CELL (2016)
Lactate Wreaks Havoc on Tumor-Infiltrating T and NK Cells
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LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
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Cell Metabolism (2016)
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HAEMATOLOGICA (2016)
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Nicole E. Scharping et al.
IMMUNITY (2016)
Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells
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IMMUNITY (2016)
Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation
Stanley Ching-Cheng Huang et al.
IMMUNITY (2016)
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Christoph Wilhelm et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor Types
Michael D. Iglesia et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2016)
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression
Valerie A. Gerriets et al.
NATURE IMMUNOLOGY (2016)
Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
Min Peng et al.
SCIENCE (2016)
TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
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The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V. Liberti et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
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Davalyn R. Powell et al.
TRENDS IN IMMUNOLOGY (2016)
Dendritic Cells and Cancer Immunity
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TRENDS IN IMMUNOLOGY (2016)
IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance
David H. Munn et al.
TRENDS IN IMMUNOLOGY (2016)
The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
Vinit Kumar et al.
TRENDS IN IMMUNOLOGY (2016)
TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype
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ONCOTARGET (2016)
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Luke A. J. O'Neill
CELL REPORTS (2016)
Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages
Jan Van den Bossche et al.
CELL REPORTS (2016)
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Cell Reports (2016)
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Iris de Weerdt et al.
HAEMATOLOGICA (2016)
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Michael D. Iglesia et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2016)
TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
Sebastien Viel et al.
SCIENCE SIGNALING (2016)
T-bet and Eomesodermin in NK Cell Development, Maturation, and Function
Federico Simonetta et al.
FRONTIERS IN IMMUNOLOGY (2016)
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Amir A. Al-Khami et al.
ONCOIMMUNOLOGY (2016)
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ONCOIMMUNOLOGY (2016)
B Lymphocytes and Cancer: A Love-Hate Relationship
Grace J. Yuen et al.
TRENDS IN CANCER (2016)
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Luke A. J. O'Neill et al.
NATURE REVIEWS IMMUNOLOGY (2016)
Neutrophils in cancer: neutral no more
Seth B. Coffelt et al.
NATURE REVIEWS CANCER (2016)
β-Catenin Promotes Regulatory T-cell Responses in Tumors by Inducing Vitamin A Metabolism in Dendritic Cells
Yuan Hong et al.
CANCER RESEARCH (2015)
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
Chih-Hao Chang et al.
CELL (2015)
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Beth Kelly et al.
CELL RESEARCH (2015)
Acquisition and Presentation of Tumor Antigens by Dendritic Cells
Irene Bonaccorsi et al.
CRITICAL REVIEWS IN IMMUNOLOGY (2015)
Regulatory B Cells: Origin, Phenotype, and Function
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IMMUNITY (2015)
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High Mitochondrial Respiration and Glycolytic Capacity Represent a Metabolic Phenotype of Human Tolerogenic Dendritic Cells
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JOURNAL OF IMMUNOLOGY (2015)
Activation-Specific Metabolic Requirements for NK Cell IFN-γ Production
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JOURNAL OF IMMUNOLOGY (2015)
Inflammatory ILC2 cells: disguising themselves as progenitors?
Shigeo Koyasu
NATURE IMMUNOLOGY (2015)
CD47 blockade as another immune checkpoint therapy for cancer
Robert H. Vonderheide
NATURE MEDICINE (2015)
CD47 blockade triggers T cell-mediated destruction of immunogenic tumors
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NATURE MEDICINE (2015)
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SCIENCE SIGNALING (2015)
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Peter J. Siska et al.
TRENDS IN IMMUNOLOGY (2015)
NCR+ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures
Paolo Carrega et al.
NATURE COMMUNICATIONS (2015)
PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation
Nikolaos Patsoukis et al.
NATURE COMMUNICATIONS (2015)
M-CSF from Cancer Cells Induces Fatty Acid Synthase and PPARβ/δ Activation in Tumor Myeloid Cells, Leading to Tumor Progression
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CELL REPORTS (2015)
Mode of Bioenergetic Metabolism during B Cell Differentiation in the Intestine Determines the Distinct Requirement for Vitamin B1
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CELL REPORTS (2015)
Lactate Regulates Metabolic and Proinflammatory Circuits in Control of T Cell Migration and Effector Functions
Robert Haas et al.
PLOS BIOLOGY (2015)
Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation
Dorota Klysz et al.
SCIENCE SIGNALING (2015)
Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy
Alisha Holtzhausen et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies
Fokhrul Hossain et al.
CANCER IMMUNOLOGY RESEARCH (2015)
The Regulatory Role of Invariant NKT Cells in Tumor Immunity
Rosanna M. McEwen-Smith et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
Valerie A. Gerriets et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
IL-25-responsive, lineage-negative KLRG1hi cells are multipotential 'inflammatory' type 2 innate lymphoid cells
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NATURE IMMUNOLOGY (2015)
Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
Abhishek K. Jha et al.
IMMUNITY (2015)
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Nilushi S. De Silva et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Presence of B Cells in Tertiary Lymphoid Structures Is Associated with a Protective Immunity in Patients with Lung Cancer
Claire Germain et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
Fatty acid oxidation is dispensable for human macrophage IL-4-induced polarization
Dmitry Namgaladze et al.
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Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish
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BLOOD (2014)
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CANCER CELL (2014)
Activity of the Monocarboxylate Transporter 1 Inhibitor AZD3965 in Small Cell Lung Cancer
Radoslaw Polanski et al.
CLINICAL CANCER RESEARCH (2014)
Prognostic B-cell Signatures Using mRNA-Seq in Patients with Subtype-Specific Breast and Ovarian Cancer
Michael D. Iglesia et al.
CLINICAL CANCER RESEARCH (2014)
INNATE LYMPHOID CELLS: IMMUNOREGULATORY CELLS OF MUCOSAL INFLAMMATION
V. Kumar
EUROPEAN JOURNAL OF INFLAMMATION (2014)
Inflammatory T Cell Responses Rely on Amino Acid Transporter ASCT2 Facilitation of Glutamine Uptake and mTORC1 Kinase Activation
Mako Nakaya et al.
IMMUNITY (2014)
Innate lymphoid cells: New paradigm in immunology of inflammation
Vijay Kumar
IMMUNOLOGY LETTERS (2014)
p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8+ T cells
Sian M. Henson et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow
Cecile Daussy et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
PD-L1 is a novel direct target of HIF-1α., and its blockade under hypoxia enhanced MDSC-mediated T cell activation
Muhammad Zaeem Noman et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
mTORC1-Dependent Metabolic Reprogramming Is a Prerequisite for NK Cell Effector Function
Raymond P. Donnelly et al.
JOURNAL OF IMMUNOLOGY (2014)
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKε supports the anabolic demands of dendritic cell activation
Bart Everts et al.
NATURE IMMUNOLOGY (2014)
The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells
Antoine Marais et al.
NATURE IMMUNOLOGY (2014)
Regulatory B cells are induced by gut microbiota-driven interleukin-1β and interleukin-6 production
Elizabeth C. Rosser et al.
NATURE MEDICINE (2014)
Interleukin-35 induces regulatory B cells that suppress autoimmune disease
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NATURE MEDICINE (2014)
Tumoricidal activity of human dendritic cells
Jurjen Tel et al.
TRENDS IN IMMUNOLOGY (2014)
Polyamine-Blocking Therapy Reverses Immunosuppression in the Tumor Microenvironment
Candace S. Hayes et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Polarization of ILC2s in Peripheral Blood Might Contribute to Immunosuppressive Microenvironment in Patients with Gastric Cancer
Qingli Bie et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2014)
Metabolic Regulation of T Lymphocytes
Nancie J. MacIver et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)
Tumor Microenvironmental Conversion of Natural Killer Cells into Myeloid-Derived Suppressor Cells
Young-Jun Park et al.
CANCER RESEARCH (2013)
Cancer metabolism: Key players in metabolic reprogramming
Tomoyoshi Soga
CANCER SCIENCE (2013)
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
Chih-Hao Chang et al.
CELL (2013)
Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
Gabriela Bindea et al.
IMMUNITY (2013)
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
Madhusudhanan Sukumar et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Role of Fatty-Acid Synthesis in Dendritic Cell Generation and Function
Adeel Rehman et al.
JOURNAL OF IMMUNOLOGY (2013)
Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells
Zaheed Husain et al.
JOURNAL OF IMMUNOLOGY (2013)
Type 2 innate lymphoid cells control eosinophil homeostasis
Jesse C. Nussbaum et al.
NATURE (2013)
Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
Linda V. Sinclair et al.
NATURE IMMUNOLOGY (2013)
Innate and adaptive immune cells in the tumor microenvironment
Thomas F. Gajewski et al.
NATURE IMMUNOLOGY (2013)
Adenosine as an endogenous immunoregulator in cancer pathogenesis: where to go?
V. Kumar
PURINERGIC SIGNALLING (2013)
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TRENDS IN CELL BIOLOGY (2013)
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Zaheed Husain et al.
ONCOIMMUNOLOGY (2013)
Neutrophil recruitment and function in health and inflammation
Elzbieta Kolaczkowska et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes
Andrea Cerutti et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Decisions About Dendritic Cells: Past, Present, and Future
Ralph M. Steinman
ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 (2012)
L-glutamine is a key parameter in the immunosuppression phenomenon
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Immunosuppressive activity enhances central carbon metabolism and bioenergetics in myeloid-derived suppressor cells in vitro models
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BMC CELL BIOLOGY (2012)
The Transcription Factors T-bet and Eomes Control Key Checkpoints of Natural Killer Cell Maturation
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IMMUNITY (2012)
Activated CD69+ T Cells Foster Immune Privilege by Regulating IDO Expression in Tumor-Associated Macrophages
Qiyi Zhao et al.
JOURNAL OF IMMUNOLOGY (2012)
MicroRNA-494 Is Required for the Accumulation and Functions of Tumor-Expanded Myeloid-Derived Suppressor Cells via Targeting of PTEN
Yang Liu et al.
JOURNAL OF IMMUNOLOGY (2012)
Pivotal Advance: Arginase-1-independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced expression of inflammatory genes
Jan Van den Bossche et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2012)
The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry
David Dominguez-Sola et al.
NATURE IMMUNOLOGY (2012)
Hallmarks of cancer: of all cancer cells, all the time?
Sebastien L. Floor et al.
TRENDS IN MOLECULAR MEDICINE (2012)
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AGING-US (2011)
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Matthew D. Vesely et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 29 (2011)
Lactate: A Metabolic Key Player in Cancer
Franziska Hirschhaeuser et al.
CANCER RESEARCH (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
Ruoning Wang et al.
IMMUNITY (2011)
The mechanisms by which polyamines accelerate tumor spread
Kuniyasu Soda
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2011)
HIF1α-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
Lewis Z. Shi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
Ryan D. Michalek et al.
JOURNAL OF IMMUNOLOGY (2011)
Compartmentalization of the nucleus
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TRENDS IN CELL BIOLOGY (2011)
Regulation of cancer cell metabolism
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NATURE REVIEWS CANCER (2011)
Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation
Connie M. Krawczyk et al.
BLOOD (2010)
HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
Cesar A. Corzo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells
Joshua D. Mezrich et al.
JOURNAL OF IMMUNOLOGY (2010)
B Cells Are Required for Optimal CD4+ and CD8+ T Cell Tumor Immunity: Therapeutic B Cell Depletion Enhances B16 Melanoma Growth in Mice
David J. DiLillo et al.
JOURNAL OF IMMUNOLOGY (2010)
Targeting dendritic cell metabolism in cancer
Laurence Zitvogel et al.
NATURE MEDICINE (2010)
Lipid accumulation and dendritic cell dysfunction in cancer
Donna L. Herber et al.
NATURE MEDICINE (2010)
The polarization of immune cells in the tumour environment by TGFβ
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NATURE REVIEWS IMMUNOLOGY (2010)
Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: N1 versus N2 TAN
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CANCER CELL (2009)
Adenosine: An endogenous modulator of innate immune system with therapeutic potential
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EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment
Greg M. Delgoffe et al.
IMMUNITY (2009)
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
Loise M. Francisco et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Myeloid-derived suppressor cells as regulators of the immune system
Dmitry I. Gabrilovich et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Adenosine receptors in regulation of dendritic cell differentiation and function
Sergey V. Novitskiy et al.
BLOOD (2008)
Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
Candace M. Cham et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase
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JOURNAL OF CLINICAL INVESTIGATION (2007)
Metabolic mechanisms of cancer-induced inhibition of immune responses
Antonella Viola et al.
SEMINARS IN CANCER BIOLOGY (2007)
Immune surveillance of tumors
Jeremy B. Swann et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Inhibitory effect of tumor cell-derived lactic acid on human T cells
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BLOOD (2007)
Regulation of carcinogenesis by IL-5 and CCL11: A potential role for eosinophils in tumor immune surveillance
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JOURNAL OF IMMUNOLOGY (2007)
Cell-autonomous control of interferon type I expression by indoleamine 2,3-dioxygenase in regulatory CD19(+) dendritic cells
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EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
Tryptophan catabolism generates autoimmune-preventive regulatory T cells
Francesca Fallarino et al.
TRANSPLANT IMMUNOLOGY (2006)
Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response
Peter J. Murray
CURRENT OPINION IN PHARMACOLOGY (2006)
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor ζ-chain and induce a regulatory phenotype in naive T cells
Francesca Fallarino et al.
JOURNAL OF IMMUNOLOGY (2006)
The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells
Nuno L. Alves et al.
IMMUNITY (2006)
Acid-mediated tumor invasion: a multidisciplinary study
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CANCER RESEARCH (2006)
Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO
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EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
Regulation of immune responses by L- arginine metabolism
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NATURE REVIEWS IMMUNOLOGY (2005)
Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis
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MOLECULAR AND CELLULAR BIOLOGY (2005)
Interchromosomal associations between alternatively expressed loci
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NATURE (2005)
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
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IMMUNITY (2005)
De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent
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CANCER CELL (2005)
Hypoxia-induced neutrophil survival is mediated by HIF-1α-dependent NF-κB activity
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JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Drug-induced increase of carcinoembryonic antigen expression in cancer cells
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PHARMACOLOGICAL RESEARCH (2004)
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
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NATURE MEDICINE (2004)
Prognostic significance of tissue transglutaminase in drug resistant and metastatic breast cancer
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CLINICAL CANCER RESEARCH (2004)
XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum
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JOURNAL OF CELL BIOLOGY (2004)
Long-range intrachromosomal interactions in the T helper type 2 cytokine locus
CG Spilianakis et al.
NATURE IMMUNOLOGY (2004)
Applying the principles of stem-cell biology to cancer
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NATURE REVIEWS CANCER (2003)
Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade
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INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2002)
Impaired perforin-dependent NK cell cytotoxicity and proliferative activity of peripheral blood T cells is associated with metastatic melanoma
V Jovic et al.
TUMORI JOURNAL (2001)
Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population
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LANCET (2000)
CD91: a receptor for heat shock protein gp96
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NATURE IMMUNOLOGY (2000)