Advances in Schiff Base and Its Coating on Metal Biomaterials-A Review

In recent years, metal biomaterials have emerged one after another, and have many excellent properties, playing a great role in medicine. However, these coatings cannot meet the medical needs in every aspect. Schiff base is an important organic synthetic reagent and liquid crystal material in organic chemistry. It mainly refers to a class of organic compounds containing imine or azomethine characteristic groups (-RC=N-). It has important anti-tumor, anti-virus, antifungal and antibacterial activities. Based on the excellent properties of Schiff base, the coatings made of Schiff base can improve the bioactivity of materials, which have a good development prospect in medicine. In this paper, the preparation methods and properties of Schiff base and many advantages of Schiff base coatings are reviewed. The research on the modification of coatings or functional membranes by Schiff base and Schiff base reaction, as well as the extensive application of special Schiff base coatings in many fields such as anti-corrosion, antibacterial, flame retardant, etc., are carried out. Suggestions for further research on Schiff base coatings on metal biomaterials are put forward.

Automated summary

In recent years, metal biomaterials with excellent properties have been widely used in medicine. However, these coatings have limitations in meeting all medical needs. Schiff base, an important organic reagent, possesses various anti-tumor, antiviral, antifungal, and antibacterial activities. Schiff base coatings, by taking advantage of their properties, have great potential for improving the bioactivity of materials in medicine. This review highlights the preparation methods, properties, and advantages of Schiff base coatings, as well as their extensive applications in corrosion resistance, antibacterial, flame retardancy, and other fields. Suggestions for further research on Schiff base coatings for metal biomaterials are also proposed.