4.7 Article

Protective role of resveratrol against VCM-induced hepatotoxicity in male wistar rats

Related references

Note: Only part of the references are listed.
Article Chemistry, Medicinal

Hepatic-Targeted Nano-enzyme with Resveratrol Loading for Precise Relief of Nonalcoholic Steatohepatitis

Yili Tong et al.

Summary: In this study, liver-targeted Ce-based hollow mesoporous nanocarriers loaded with bioactive drugs were successfully constructed. The nanosystem enhanced cellular drug uptake and effectively treated nonalcoholic steatohepatitis, resulting in the recovery of liver function.

CHEMMEDCHEM (2023)

Review Pharmacology & Pharmacy

Hepatoprotective and therapeutic effects of resveratrol: A focus on anti-inflammatory and antioxidative activities

Supat Chupradit et al.

Summary: The liver is a vital organ in the body, and resveratrol (RES) exhibits pharmacological activities that can treat various liver diseases by reducing inflammation, inducing apoptosis, and reducing oxidative stress.

FUNDAMENTAL & CLINICAL PHARMACOLOGY (2022)

Article Cell Biology

Resveratrol Alleviates Hepatic Fibrosis in Associated with Decreased Endoplasmic Reticulum Stress-Mediated Apoptosis and Inflammation

Zhenyu Ma et al.

Summary: Resveratrol (RSV) exerts a protective effect in a CCl4-induced rat model of hepatic fibrosis (HF) by reducing collagen deposition, reversing epithelial-mesenchymal transition, and decreasing apoptosis and inflammation induced by endoplasmic reticulum stress (ERS).

INFLAMMATION (2022)

Article Infectious Diseases

Antibiotics and Liver Cirrhosis: What the Physicians Need to Know

Caterina Zoratti et al.

Summary: This narrative review aims to provide physicians with basic and practical knowledge for efficiently choosing the best antibiotic therapy in patients with liver cirrhosis and ongoing infections.

ANTIBIOTICS-BASEL (2022)

Review Plant Sciences

Medicinal plants used against hepatic disorders in Bangladesh: A comprehensive review

Rajib Das et al.

Summary: The study summarizes the processes of hepatotoxicity induced by various toxins and explores identified hepatoprotective plants and their phytoconstituents, providing new directions for treating liver injury. Through literature searches and comprehensive analysis, it is found that a variety of plants offer good pharmacological evidence that can be used in the treatment of hepatic disorders.

JOURNAL OF ETHNOPHARMACOLOGY (2022)

Article Pharmacology & Pharmacy

Association of resveratrol with the suppression of TNF-α/NF-kB/iNOS/HIF-1α axis-mediated fibrosis and systemic hypertension in thioacetamide-induced liver injury

Hasnaa A. Ebrahim et al.

Summary: This study investigated the link between liver fibrosis and hypertension induced by thioacetamide, as well as the role of inflammation, nuclear factor-kappa B, nitrosative stress, and hypoxia-inducible factor-1 alpha. The findings suggest that the anti-inflammatory and antioxidant resveratrol can ameliorate the fibrosis and hypertension caused by thioacetamide.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2022)

Article Environmental Sciences

The efficiency of pomegranate (Punica granatum) peel ethanolic extract in attenuating the vancomycin-triggered liver and kidney tissues injury in rats

Khlood M. El Bohi et al.

Summary: The study found that Punica granatum peel ethanol extract (PPEE) has potential to attenuate liver and kidney tissue injury induced by vancomycin treatment in rats, by reducing oxidative damage, inflammation, and apoptotic cell death. Administering PPEE prior to vancomycin medication showed more effective restoration efficacy.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2021)

Article Geriatrics & Gerontology

Antioxidant effect of Resveratrol: Change in MAPK cell signaling pathway during the aging process

Milena Almeida Santos et al.

Summary: Aging is associated with an increase in ROS levels, and resveratrol can reduce ROS levels in both age groups, with greater efficiency observed in the middle-aged group. Inhibiting PKA, Akt/PKB, and MAPK signaling pathways can alter the antioxidant effects of resveratrol and change the signaling pattern of the MAPK pathway during the aging process.

ARCHIVES OF GERONTOLOGY AND GERIATRICS (2021)

Article Behavioral Sciences

Effects of melatonin and resveratrol on recognition memory and passive avoidance performance in a mouse model of Alzheimer's disease

Samah Labban et al.

Summary: This study showed that melatonin and resveratrol had positive effects on improving memory deficits in a sporadic mouse model of Alzheimer's disease, with better outcomes when used in combination. Additionally, both substances enhanced the cholinergic system and BDNF, CREB signaling pathways in the prefrontal cortex in the AD mouse model.

BEHAVIOURAL BRAIN RESEARCH (2021)

Review Infectious Diseases

The monitoring of vancomycin: a systematic review and meta-analyses of area under the concentration-time curve-guided dosing and trough-guided dosing

Moeko Tsutsuura et al.

Summary: This systematic review and meta-analysis investigated the relationship between VCM monitoring strategies and its effectiveness and safety. Findings suggest that VCM trough concentrations and AUC values are correlated with outcomes. AUC-guided monitoring may have potential in reducing nephrotoxicity compared to trough-guided monitoring.

BMC INFECTIOUS DISEASES (2021)

Article Immunology

Intravenous to Oral Switch in Complicated Staphylococcus aureus Bacteremia Without Endovascular Infection: A Retrospective Single-Center Cohort Study

Ilse J. E. Kouijzer et al.

Summary: This retrospective cohort study found that patients with disseminated Staphylococcus aureus bacteremia, who did not have endovascular infection on echocardiography and F-18-FDG-PET/CT, were successfully treated without relapse after IV-oral switch. The mortality rate was low and comparable to those who received prolonged intravenous treatment, and IV-oral switch was associated with a shorter hospital stay.

CLINICAL INFECTIOUS DISEASES (2021)

Article Biochemistry & Molecular Biology

Antioxidant, anti-inflammatory and neuroprotective actions of resveratrol after experimental nervous system insults. Special focus on the molecular mechanisms involved

C. A. Miguel et al.

Summary: Secondary damage is a key factor in promoting cell death, neurodegeneration, and functional deficits following acute central nervous system insults. Resveratrol, a natural compound found in grape skin and red wine, has shown potential neuroprotective effects by modulating multiple pathways involved in antioxidant, anti-inflammatory, and anti-apoptotic processes.

NEUROCHEMISTRY INTERNATIONAL (2021)

Review Biochemistry & Molecular Biology

The potential effect of phytochemicals and herbal plant remedies for treating drug-induced hepatotoxicity: a review

Manisha Parthasarathy et al.

Summary: Drug-induced liver injury, primarily caused by synthetic drugs, poses a significant challenge for patients and physicians. Traditional medicines are being explored as an alternative therapy due to their pharmacological benefits, minimal side effects, and natural availability. Phytochemicals, essential components of plants, have shown promise in reducing cell death, restoring antioxidant defense mechanisms, limiting oxidative stress, and preventing tissue inflammation and mitochondrial dysfunction in treating drug-induced hepatotoxicity.

MOLECULAR BIOLOGY REPORTS (2021)

Article Clinical Neurology

Melatonin Improves Short-Term Spatial Memory in a Mouse Model of Alzheimer's Disease

Samah Labban et al.

Summary: This study demonstrated the potential of melatonin (MLT) to alleviate spatial memory impairment in sporadic Alzheimer's disease (AD) mice. MLT improved gene expression related to memory in the hippocampus of AD model mice.

DEGENERATIVE NEUROLOGICAL AND NEUROMUSCULAR DISEASE (2021)

Article Microbiology

The risk of vancomycin toxicity in patients with liver impairment

Luigi Brunetti et al.

ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS (2020)

Review Gastroenterology & Hepatology

Comprehensive review of hepatotoxicity associated with traditional Indian Ayurvedic herbs

Cyriac Abby Philips et al.

WORLD JOURNAL OF HEPATOLOGY (2020)

Review Plant Sciences

The natural phenolic compounds as modulators of NADPH oxidases in hypertension

Mozhdeh Yousefian et al.

PHYTOMEDICINE (2019)

Article Medicine, Research & Experimental

Genistein can ameliorate hepatic inflammatory reaction in nonalcoholic steatohepatitis rats

Yimin Yin et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

Article Medicine, Research & Experimental

Green tea polyphenols attenuate hepatic steatosis, and reduce insulin resistance and inflammation in high-fat diet-induced rats

Hong-Miao Xia et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2019)

Article Biochemistry & Molecular Biology

The effects of zingerone against vancomycin-induced lung, liver, kidney and testis toxicity in rats: The behavior of some metabolic enzymes

Cuneyt Caglayan et al.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2019)

Review Biochemistry & Molecular Biology

Functions and dysfunctions of nitric oxide in brain

Pol Picon-Pages et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)

Review Neurosciences

Molecular Mechanisms Underlying the Anti-depressant Effects of Resveratrol: a Review

Marcos Roberto de Oliveira et al.

MOLECULAR NEUROBIOLOGY (2018)

Article Medicine, Research & Experimental

Hepatoprotective effect of berberine against methotrexate induced liver toxicity in rats

Saeed Mehrzadi et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Article Biochemistry & Molecular Biology

Hepatoprotective effects exerted by Poria Cocos polysaccharides against acetaminophen-induced liver injury in mice

Ka Wu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Review Medicine, Research & Experimental

Role of Reduced Nitric Oxide in Liver Cell Apoptosis Inhibition During Liver Damage

Ying-yi Wang et al.

ARCHIVES OF MEDICAL RESEARCH (2018)

Article Medicine, General & Internal

The effects of resveratrol on hepatic oxidative stress in metabolic syndrome model induced by high fructose diet

Yilmaz C. Demirtas et al.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY (2018)

Article Gastroenterology & Hepatology

IL-6 Trans-Signaling Is Essential for the Development of Hepatocellular Carcinoma in Mice

Juri Bergmann et al.

HEPATOLOGY (2017)

Article Medicine, Research & Experimental

Vitamin E (α tocopherol) attenuates toxicity and oxidative stress induced by aflatoxin in rats

Seval Yilmaz et al.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE (2017)

Article Biochemistry & Molecular Biology

Resveratrol Exerts Antioxidant Effects by Activating SIRT2 To Deacetylate Prx1

Yanchao Pan et al.

BIOCHEMISTRY (2017)

Article Food Science & Technology

Resveratrol Regulates Activated Hepatic Stellate Cells by Modulating NF-κB and the PI3K/Akt Signaling Pathway

De-Quan Zhang et al.

JOURNAL OF FOOD SCIENCE (2016)

Review Gastroenterology & Hepatology

Antibiotic Prophylaxis in Cirrhosis: Good and Bad

Javier Fernandez et al.

HEPATOLOGY (2016)

Review Endocrinology & Metabolism

Review of vancomycin-induced renal toxicity: an update

Oluwatoyin Bamgbola

THERAPEUTIC ADVANCES IN ENDOCRINOLOGY AND METABOLISM (2016)

Article Multidisciplinary Sciences

Integrative Metabolic Signatures for Hepatic Radiation Injury

Irwin Jack Kurland et al.

PLOS ONE (2015)

Review Pharmacology & Pharmacy

Nitric oxide in liver diseases

Yasuko Iwakiri et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2015)

Article Gastroenterology & Hepatology

The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice

Yingqun Zhou et al.

GASTROENTEROLOGY RESEARCH AND PRACTICE (2015)

Review Nutrition & Dietetics

Hepatic Steatosis as a Marker of Metabolic Dysfunction

Elisa Fabbrini et al.

NUTRIENTS (2015)

Article Medicine, General & Internal

Liver cirrhosis

Emmanuel A. Tsochatzis et al.

LANCET (2014)

Article Food Science & Technology

Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases

Albino Carrizzo et al.

FOOD AND CHEMICAL TOXICOLOGY (2013)

Review Medicine, General & Internal

Acute Liver Failure

William Bernal et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Review Oncology

Nitric oxide and cancer: a review

Sheetal Korde Choudhari et al.

WORLD JOURNAL OF SURGICAL ONCOLOGY (2013)

Article Pharmacology & Pharmacy

Alanine Aminotransferase: A Clinical and Regulatory Tool for Detecting Liver Injury-Past, Present, and Future

J. R. Senior

CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)

Article Pathology

Protective role of curcumin in nephrotoxic oxidative damage induced by vancomycin in rats

Mohamed H. S. Ahmida

EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY (2012)

Review Gastroenterology & Hepatology

Acute-on chronic liver failure

Rajiv Jalan et al.

JOURNAL OF HEPATOLOGY (2012)

Article Gastroenterology & Hepatology

Tissue-nonspecific Alkaline Phosphatase Is Activated in Enterocytes by Oxidative Stress Via Changes in Glycosylation

Rocio Lopez-Posadas et al.

INFLAMMATORY BOWEL DISEASES (2011)

Article Pharmacology & Pharmacy

Pharmacokinetics of vancomycin in neonates admitted to the neonatology unit at the Jordan University Hospital

E. F. Badran et al.

INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS (2011)

Review Plant Sciences

On the origins of nitric oxide

Kapuganti J. Gupta et al.

TRENDS IN PLANT SCIENCE (2011)

Article Chemistry, Medicinal

Resveratrol Inhibits Dimethylnitrosamine-Induced Hepatic Fibrosis in Rats

Eun-Sil Lee et al.

ARCHIVES OF PHARMACAL RESEARCH (2010)

Article Biochemistry & Molecular Biology

Role of IL-6 trans-signaling in CCl4 induced liver damage

Jessica Gewiese-Rabsch et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)

Article Immunology

IL-6 induces hepatic inflammation and collagen synthesis in vivo

I. CHOI et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)

Article Environmental Sciences

Resveratrol, a red wine polyphenol, attenuates lipopolysaccharide-induced oxidative stress in rat liver

Hichem Sebai et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2010)

Review Biochemistry & Molecular Biology

Apoptosis and glutathione: beyond an antioxidant

R. Franco et al.

CELL DEATH AND DIFFERENTIATION (2009)

Review Biochemistry & Molecular Biology

Glutathione in liver diseases and hepatotoxicity

Liyun Yuan et al.

MOLECULAR ASPECTS OF MEDICINE (2009)

Article Medicine, Research & Experimental

Resveratrol protects primary rat hepatocytes against necrosis induced by reactive oxygen species

J. A. Rubiolo et al.

BIOMEDICINE & PHARMACOTHERAPY (2008)

Article Gastroenterology & Hepatology

Resveratrol inhibits nonalcoholic fatty liver disease in rats

Luis Bujanda et al.

BMC GASTROENTEROLOGY (2008)

Review Food Science & Technology

Indian medicinal herbs as sources of antioxidants

Shahin Sharif Ali et al.

FOOD RESEARCH INTERNATIONAL (2008)

Review Gastroenterology & Hepatology

Mechanisms of hepatic fibrogenesis

Scott L. Friedman

GASTROENTEROLOGY (2008)

Review Cardiac & Cardiovascular Systems

Dietary polyphenols: Good, bad, or indifferent for your health?

Barry Halliwell

CARDIOVASCULAR RESEARCH (2007)

Article Cell Biology

Protective role of erdosteine on vancomycin-induced oxidative stress in rat liver

Mehmet Sahin et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2006)

Article Pharmacology & Pharmacy

Vancomycin-induced elevation of liver enzyme levels

RM Cadle et al.

ANNALS OF PHARMACOTHERAPY (2006)

Article Gastroenterology & Hepatology

Protective effects of resveratrol against acetaminophen-induced toxicity in mice

Goksel Sener et al.

HEPATOLOGY RESEARCH (2006)

Review Medicine, Research & Experimental

Role of nitric oxide in liver injury

T Chen et al.

CURRENT MOLECULAR MEDICINE (2003)

Article Oncology

Nitric oxide levels and lipid peroxidation in plasma of patients with gastric cancer

E Bakan et al.

JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2002)

Review Biochemistry & Molecular Biology

Prooxidant and antioxidant functions of nitric oxide in liver toxicity

JD Laskin et al.

ANTIOXIDANTS & REDOX SIGNALING (2001)

Article Public, Environmental & Occupational Health

Drug-induced liver disorders - Implications for drug development and regulation

N Kaplowitz

DRUG SAFETY (2001)

Review Medical Laboratory Technology

Effects of hepatic function on vancomycin pharmacokinetics in patients with cancer

A Aldaz et al.

THERAPEUTIC DRUG MONITORING (2000)