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H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation
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Disruption of an EHMT1-Associated Chromatin-Modification Module Causes Intellectual Disability
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Recruitment and Biological Consequences of Histone Modification of H3K27me3 and H3K9me3
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ILAR JOURNAL (2012)
Directional Neuronal Migration Is Impaired in Mice Lacking Adenomatous Polyposis Coli 2
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Brian J. O'Roak et al.
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Eric J. Wagner et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders
Brian J. O'Roak et al.
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Mutations in the β-Tubulin Gene TUBB5 Cause Microcephaly with Structural Brain Abnormalities
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REST-Mediated Recruitment of Polycomb Repressor Complexes in Mammalian Cells
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Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing
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PLOS GENETICS (2012)
Immune function genes CD99L2, JARID2 and TPO show association with autism spectrum disorder
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J. A. Rosenfeld et al.
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Development and Evolution of the Human Neocortex
Jan H. Lui et al.
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EUROPEAN JOURNAL OF NEUROSCIENCE (2011)
H3K36 Methylation Antagonizes PRC2-mediated H3K27 Methylation
Wen Yuan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Deletion of 14-3-3ε and CRK: A Clinical Syndrome With Macrocephaly, Developmental Delay, and Generalized Epilepsy
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Oblique Radial Glial Divisions in the Developing Mouse Neocortex Induce Self-Renewing Progenitors outside the Germinal Zone That Resemble Primate Outer Subventricular Zone Progenitors
Atsunori Shitamukai et al.
JOURNAL OF NEUROSCIENCE (2011)
Dual Function of Histone H3 Lysine 36 Methyltransferase ASH1 in Regulation of Hox Gene Expression
Yujiro Tanaka et al.
PLOS ONE (2011)
Functional characterization of the zebrafish WHSC1-related gene, a homolog of human NSD2
Toshiko Yamada-Okabe et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
A syndrome of short stature, microcephaly and speech delay is associated with duplications reciprocal to the common Sotos syndrome deletion
Luis M. Franco et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2010)
Renewed focus on the developing human neocortex
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JOURNAL OF ANATOMY (2010)
Changes in Prefrontal Axons May Disrupt the Network in Autism
Basilis Zikopoulos et al.
JOURNAL OF NEUROSCIENCE (2010)
Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture
Timothy W. Yu et al.
NATURE GENETICS (2010)
A common mechanism for microcephaly
Bernd Wollnik
NATURE GENETICS (2010)
Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function
Agda Karina Lucio-Eterovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex
Joao D. Pereira et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Epigenetic control of inducible gene expression in the immune system
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EPIGENOMICS (2010)
Role of H3K4 demethylases in complex neurodevelopmental diseases
Christopher Wynder et al.
EPIGENOMICS (2010)
A Microdeletion at 12q24.31 Can Mimic Beckwith-Wiedemann Syndrome Neonatally
E. Baple et al.
MOLECULAR SYNDROMOLOGY (2010)
The Target of the NSD Family of Histone Lysine Methyltransferases Depends on the Nature of the Substrate
Yan Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Widespread Changes in Dendritic and Axonal Morphology in Mecp2-Mutant Mouse Models of Rett Syndrome: Evidence for Disruption of Neuronal Networks
Pavel V. Belichenko et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2009)
APC2 Plays an Essential Role in Axonal Projections through the Regulation of Microtubule Stability
Takafumi Shintani et al.
JOURNAL OF NEUROSCIENCE (2009)
Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II
Pengfei Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells
Daniel A. Lim et al.
NATURE (2009)
A genome-wide linkage and association scan reveals novel loci for autism
Lauren A. Weiss et al.
NATURE (2009)
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome
Keisuke Nimura et al.
NATURE (2009)
Evolution of the neocortex: a perspective from developmental biology
Pasko Rakic
NATURE REVIEWS NEUROSCIENCE (2009)
Polycomb Limits the Neurogenic Competence of Neural Precursor Cells to Promote Astrogenic Fate Transition
Yusuke Hirabayashi et al.
NEURON (2009)
Functional and Evolutionary Insights into Human Brain Development through Global Transcriptome Analysis
Matthew B. Johnson et al.
NEURON (2009)
Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation
Ali Shilatifard
CURRENT OPINION IN CELL BIOLOGY (2008)
Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation
John W. Edmunds et al.
EMBO JOURNAL (2008)
The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology
Scott V. Dindot et al.
HUMAN MOLECULAR GENETICS (2008)
Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes
Jeong-Heon Lee et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Mammalian ASH1L is a histone methyl transferase that occupies the transcribed region of active genes
Gregory D. Gregory et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Mutation analysis of the NSD1 gene in patients with autism spectrum disorders and macrocephaly
Joseph D. Buxbaum et al.
BMC MEDICAL GENETICS (2007)
Heterogeneity of NSD1 alterations in 116 patients with Sotos syndrome
Pascale Saugier-Veber et al.
HUMAN MUTATION (2007)
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
Karl Agger et al.
NATURE (2007)
Trithorax-group protein ASH1 methylates histone H3 lysine 36
Yujro Tanaka et al.
GENE (2007)
NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis
Gang G. Wang et al.
NATURE CELL BIOLOGY (2007)
Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2
Sandra Lubitz et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
High-resolution profiling of histone methylations in the human genome
Artern Barski et al.
CELL (2007)
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Jeong-Heon Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Mutations in α-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans
David A. Keays et al.
CELL (2007)
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James Cox et al.
TRENDS IN MOLECULAR MEDICINE (2006)
Molecular cytogenetic analysis of de novo dup(5)(q35.2q35.3) and review of the literature of pure partial trisomy 5q
Chih-Ping Chen et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2006)
Pten regulates neuronal arborization and social interaction in mice
Chang-Hyuk Kwon et al.
NEURON (2006)
Control of dendritic arborization by the phosphoinositide-3'-kinase-Akt-mammalian target of rapamycin pathway
J Jaworski et al.
JOURNAL OF NEUROSCIENCE (2005)
ASPM mutations identified in patients with primary microcephaly and seizures
J Shen et al.
JOURNAL OF MEDICAL GENETICS (2005)
NSD1 mutations in Sotos syndrome
F Faravelli
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2005)
Spatial distribution of di- and tri-methyl lysine 36 of histone H3 at active genes
AJ Bannister et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Mutation analysis of the NSD1 gene in a group of 59 patients with congenital overgrowth
M Cecconi et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2005)
A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size
J Bond et al.
NATURE GENETICS (2005)
A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3K36 methylation with transcript elongation
KO Kizer et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
The etiology of Wolf-Hirschhorn syndrome
AD Bergemann et al.
TRENDS IN GENETICS (2005)
Sotos syndrome common deletion is mediated by directly oriented subunits within inverted Sos-REP low-copy repeats
N Kurotaki et al.
HUMAN MOLECULAR GENETICS (2005)
Macrocephaly and the control of brain growth in autistic disorders
P McCaffery et al.
PROGRESS IN NEUROBIOLOGY (2005)
Epilepsy in Wolf-Hirschhorn syndrome (4p-)
K Kagitani-Shimono et al.
EPILEPSIA (2005)
Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: A major site of neurogenesis
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites
N Takei et al.
JOURNAL OF NEUROSCIENCE (2004)
The Wnt/β-catenin pathway directs neuronal differentiation of cortical neural precursor cells
Y Hirabayashi et al.
DEVELOPMENT (2004)
Increased brain size and glial cell number in CD81-null mice
EE Geisert et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2002)
Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
A Chenn et al.
SCIENCE (2002)
Identification of microcephalin, a protein implicated in determining the size of the human brain
AP Jackson et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2002)
Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia
SC Noctor et al.
JOURNAL OF NEUROSCIENCE (2002)
Haploinsufficiency of NSD1 causes Sotos syndrome
N Kurotaki et al.
NATURE GENETICS (2002)
Mouse models for the Wolf-Hirschhorn deletion syndrome
D Näf et al.
HUMAN MOLECULAR GENETICS (2001)
Functional interaction between the coactivator Drosophila CREB-binding protein and ASH1, a member of the trithorax group of chromatin modifiers
F Bantignies et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Prediction of the coding sequences of unidentified human genes.: XVII.: The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro
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DNA RESEARCH (2000)
Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells
Y Mimori-Kiyosue et al.
JOURNAL OF CELL BIOLOGY (2000)
Macrocephaly - cutis marmorata telangiectatica congenita: report of five patients and a review of the literature
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CLINICAL DYSMORPHOLOGY (2000)