☆ 4.4 Article

Effect of an Intranasal Corticosteroid on Quality of Life and Local Microbiome in Young Children With Chronic Rhinosinusitis A Randomized Clinical Trial

JAMA PEDIATRICS (2023)

Related references

Note: Only part of the references are listed.

Article Medicine, General & Internal

The Long-Term Effects of 12-Week Intranasal Steroid Therapy on Adenoid Size, Its Mucus Coverage and Otitis Media with Effusion: A Cohort Study in Preschool Children

Aleksander Zwierz et al.

Summary: The purpose of this study was to analyze the long-term effects of a 12-week course of topical steroids on adenoid size, mucus, and middle ear effusion. The results indicated that there was no significant effect on adenoid size, mucus, and otitis media with effusion (OME) three to six months after finishing the treatment. Therefore, the decision of adenoidectomy and tympanostomy should not be procrastinated.

JOURNAL OF CLINICAL MEDICINE (2022)

Add to Collection

Article Allergy

Unraveling the role of the microbiome in chronic rhinosinusitis

Alkis J. Psaltis et al.

Summary: This article provides a review of the current literature on chronic rhinosinusitis, with a particular focus on the sinonasal microbiome research, evidence of dysbiosis in the disease state, and factors that may influence the microbiome. The possible mechanisms of the disease, therapeutic implications through microbial manipulation, and deficiencies and limitations of the current research are also discussed.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2022)

Add to Collection

Review Otorhinolaryngology

A Scholarly Review of the Safety and Efficacy of Intranasal Corticosteroids Preparations in the Treatment of Chronic Rhinosinusitis

Luis Macias-Valle et al.

Summary: The scholarly review presents an update on the efficacy, safety, and distribution of intranasal corticosteroids (INCS) for chronic rhinosinusitis (CRS) treatment. Studies show significant improvement in disease-specific and general quality of life measures with all formulations of INCS, indicating the effectiveness and safety of both FDA and non-FDA approved options. Novel distribution devices may further enhance penetration to specific areas within the sinuses.

ENT-EAR NOSE & THROAT JOURNAL (2021)

Add to Collection

Review Allergy

Intranasal Corticosteroids: Topical Potency, Systemic Activity and Therapeutic Index

Peter Daley-Yates et al.

Summary: Intranasal corticosteroids are the preferred treatment option for allergic rhinitis, with variations in potency and pharmacokinetic properties influencing clinical efficacy. While higher glucocorticoid receptor binding affinity is associated with improved topical potency, there is a lack of conclusive evidence on the correlation between topical potency and clinical response in patients with more severe allergic rhinitis. It is important to consider both efficacy and systemic exposure when comparing INCS regimens for therapeutic equivalence.

JOURNAL OF ASTHMA AND ALLERGY (2021)

Add to Collection

Review Allergy

Roles of innate lymphoid cells (ILCs) in allergic diseases: The 10-year anniversary for ILC2s

Kathleen R. Bartemes et al.

Summary: ILC2, a type of innate lymphoid cell, responds rapidly to allergen exposure and environmental insults in mucosal organs by producing type 2 cytokines. In addition to being activated by epithelium-derived cytokines, ILC2s are regulated by other cytokines, eicosanoids, and neuropeptides.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

Add to Collection

Article Critical Care Medicine

Effects of Inhaled Corticosteroid/Long-Acting β2-Agonist Combination on the Airway Microbiome of Patients with Chronic Obstructive Pulmonary Disease A Randomized Controlled Clinical Trial (DISARM)

Fernando Sergio Leitao Filho et al.

Summary: This study aimed to investigate the effects of ICS/LABA on the airway microbiome in COPD patients, and the results showed that fluticasone-based ICS/LABA therapy can modify the airway microbiome in COPD, leading to a relative reduction in alpha-diversity and a greater number of bacterial taxa changes.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2021)

Add to Collection

Review Otorhinolaryngology

Intranasal Corticosteroid Therapy: Systematic Review and Meta-analysis of Reported Safety and Adverse Effects in Children

Angela M. Donaldson et al.

OTOLARYNGOLOGY-HEAD AND NECK SURGERY (2020)

Add to Collection

Article Microbiology

Antibiotic Treatment for Chronic Rhinosinusitis: Prescription Patterns and Associations With Patient Outcome and the Sinus Microbiota

Christian A. Lux et al.

FRONTIERS IN MICROBIOLOGY (2020)

Add to Collection

Review Allergy

Contributions of Innate Lymphoid Cells in Chronic Rhinosinusitis

Amber U. Luong et al.

CURRENT ALLERGY AND ASTHMA REPORTS (2019)

Add to Collection

Article Allergy

Single Nucleotide Polymorphisms in Chemosensory Pathway Genes GNB3, TAS2R19, and TAS2R38 Are Associated with Chronic Rhinosinusitis

Phillip R. Purnell et al.

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2019)

Add to Collection

Article Multidisciplinary Sciences

Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients

David Michalovich et al.

NATURE COMMUNICATIONS (2019)

Add to Collection

Review Otorhinolaryngology

The Sinus and Nasal Quality of Life Survey (SN-5) in the Management of Pediatric Chronic Rhinosinusitis: A systematic review and meta-analysis

Jonathan S. Ni et al.

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY (2018)

Add to Collection

Article Immunology

Chronic Rhinosinusitis: Potential Role of Microbial Dysbiosis and Recommendations for Sampling Sites

Elizabeth Copeland et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2018)

Add to Collection

Article Otorhinolaryngology

Untitled

International Forum of Allergy & Rhinology (2018)

Add to Collection

Article Otorhinolaryngology

Untitled

International Forum of Allergy & Rhinology (2018)

Add to Collection

Article Microbiology

Compositionally and functionally distinct sinus microbiota in chronic rhinosinusitis patients have immunological and clinically divergent consequences

Emily K. Cope et al.

MICROBIOME (2017)

Add to Collection

Article Dermatology

Cutaneous microbiome effects of fluticasone propionate cream and adjunctive bleach baths in childhood atopic dermatitis

Mercedes E. Gonzalez et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2016)

Add to Collection

Article Microbiology

Chronic rhinosinusitis: a microbiome in dysbiosis and the search for alternative treatment options

Amanda Bordin et al.

MICROBIOLOGY AUSTRALIA (2016)

Add to Collection

Article Critical Care Medicine

Comparison of the Respiratory Microbiome in Healthy Nonsmokers and Smokers

Alison Morris et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)

Add to Collection

Review Respiratory System

Climate change, extreme weather events, air pollution and respiratory health in Europe

M. De Sario et al.

EUROPEAN RESPIRATORY JOURNAL (2013)

Add to Collection

Article Endocrinology & Metabolism

Lack of bone metabolism side effects after 3 years of nasal topical steroids in children with allergic rhinitis

Ozkaya Emin et al.

JOURNAL OF BONE AND MINERAL METABOLISM (2011)

Add to Collection

Article Otorhinolaryngology

The role of allergy in rhinosinusitis

Harshita Pant et al.

CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY (2009)

Add to Collection

Article Otorhinolaryngology

Quality of life for children with persistent sinonasal symptoms

DJ Kay et al.

OTOLARYNGOLOGY-HEAD AND NECK SURGERY (2003)

Add to Collection

© Peeref 2019-2024. All rights reserved.