Studying pulmonary fibrosis due to microbial infection via automated microscopic image analysis

Article Radiology, Nuclear Medicine & Medical Imaging

Six-month Follow-up Chest CT Findings after Severe COVID-19 Pneumonia

Xiaoyu Han et al.

Summary: The study found that over one-third of severe COVID-19 patients showed fibrotic-like changes in the lung at 6-month follow-up CT, which were associated with older age, acute respiratory distress syndrome, longer hospital stays, tachycardia, noninvasive mechanical ventilation, and higher initial chest CT score.

RADIOLOGY (2021)

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Review Medicine, Research & Experimental

Virus infection induced pulmonary fibrosis

Wei Jie Huang et al.

Summary: Pulmonary fibrosis, the end stage of various lung diseases, may be triggered by virus infection, but the specific mechanisms are not fully understood. Studying the relationship between pulmonary fibrosis and various viruses, as well as the infection mechanisms, may provide insights into potential anti-fibrotic treatment targets.

JOURNAL OF TRANSLATIONAL MEDICINE (2021)

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Review Oncology

Macrophage-stroma interactions in fibrosis: biochemical, biophysical, and cellular perspectives

Gwenda F. Vasse et al.

Summary: This review discusses the interactions between macrophages and (fibrotic) stroma from biochemical, biophysical, and cellular perspectives. Future perspectives on how macrophage-stroma interactions can be further examined for more specific targeting in the treatment of fibrosis are provided.

JOURNAL OF PATHOLOGY (2021)

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Letter Infectious Diseases