4.7 Article

Case Report: A case of Chlamydia psittaci infection in an HIV patient

Journal

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fcimb.2023.1185803

Keywords

Chlamydia psittaci; psittacosis; next-generation sequencing; diagnosis; genotype

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This case describes the first report of a psittacosis infection in a human immunodeficiency virus infected patient in Zhejiang Province. The pathogen responsible for the disease, Chlamydia psittaci, has the ability to infect a wide range of birds and humans. Confirmation of C. psittaci infection was done using nested polymerase chain reaction (PCR) and Real-Time PCR, with phylogenetic analysis revealing clustering with genotype A. This study emphasizes the importance of considering psittacosis in patients with chronic diseases such as HIV, and highlights the need for increased awareness and surveillance of psittacosis in China.
Chlamydia psittaci is the pathogen of psittacosis and infects a wide range of birds and even humans. Human infection occurs most commonly in those with a history of contact with birds or poultry. We describe a case of psittacosis in a human immunodeficiency virus infected patient in Zhejiang Province for the first time. C. psittaci infection was confirmed by nested polymerase chain reaction (PCR) and Real-Time PCR. Phylogenetic analysis revealed that the sequences from the patient's samples clustered with genotype A in the same branch. Our study highlights the possibility of diagnosing psittacosis in patients with a chronic disease such as HIV-infected patients, and should increase awareness and surveillance of psittacosis in China.

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