Related references
Note: Only part of the references are listed.HIPK2 in the physiology of nervous system and its implications in neurological disorders
F. Sardina et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2023)
Novel elasticity measurements reveal C. elegans cuticle stiffens with age and in a long-lived mutant
Mohammad Rahimi et al.
BIOPHYSICAL JOURNAL (2022)
Primary cilia and ciliary signaling pathways in aging and age-related brain disorders
Rong Ma et al.
NEUROBIOLOGY OF DISEASE (2022)
AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models
Mihaly Varadi et al.
NUCLEIC ACIDS RESEARCH (2022)
Ensembl 2022
Fiona Cunningham et al.
NUCLEIC ACIDS RESEARCH (2022)
Chaperone networks are shaped by cellular differentiation and identity
Khairun Nisaa et al.
TRENDS IN CELL BIOLOGY (2022)
Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes
Manusnan Suriyalaksh et al.
ISCIENCE (2022)
Single cell RNA-sequencing: A powerful yet still challenging technology to study cellular heterogeneity
May Ke et al.
BIOESSAYS (2022)
The Intestine as a Lifespan- and Proteostasis-Promoting Signaling Tissue
Francesca Hodge et al.
FRONTIERS IN AGING (2022)
A hitchhiker's guide to single-cell transcriptomics and data analysis pipelines
Richa Nayak et al.
GENOMICS (2021)
The landscape of molecular chaperones across human tissues reveals a layered architecture of core and variable chaperones
Netta Shemesh et al.
NATURE COMMUNICATIONS (2021)
The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing
Yincong Zhang et al.
NATURE COMMUNICATIONS (2021)
Integrated analysis of multimodal single-cell data
Yuhan Hao et al.
CELL (2021)
Molecular topography of an entire nervous system
Seth R. Taylor et al.
CELL (2021)
Highly accurate protein structure prediction with AlphaFold
John Jumper et al.
NATURE (2021)
Tribbles pseudokinase NIPI-3 regulates intestinal immunity in Caenorhabditis elegans by controlling SKN-1/Nrf activity
Chenggang Wu et al.
CELL REPORTS (2021)
Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans
Maria Lazaro-Pena et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2021)
Single-cell RNA sequencing technologies and bioinformatics pipelines (vol 50, pg 1, 2018)
Byungjin Hwang et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2021)
Cell-Nonautonornous Regulation of Proteostasis in Aging and Disease
Richard I. Morimoto
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2020)
Loss of HIPK2 Protects Neurons from Mitochondrial Toxins by Regulating Parkin Protein Turnover
Jiasheng Zhang et al.
JOURNAL OF NEUROSCIENCE (2020)
WormBase: a modern Model Organism Information Resource
Todd W. Harris et al.
NUCLEIC ACIDS RESEARCH (2020)
The reactome pathway knowledgebase
Bijay Jassal et al.
NUCLEIC ACIDS RESEARCH (2020)
Four glial cells regulate ER stress resistance and longevity via neuropeptide signaling in C. elegans
Ashley E. Frakes et al.
SCIENCE (2020)
Homeodomain-interacting protein kinase (Hipk) plays roles in nervous system and muscle structure and function
Simon J. H. Wang et al.
PLOS ONE (2020)
Divergent Nodes of Non-autonomous UPRER Signaling through Serotonergic and Dopaminergic Neurons
Ryo Higuchi-Sanabria et al.
CELL REPORTS (2020)
Cell non-autonomous regulation of health and longevity
Hillary A. Miller et al.
ELIFE (2020)
Emerging topics in C-elegans aging research: Transcriptional regulation, stress response and epigenetics
Martin S. Denzel et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2019)
Neuronal XBP-1 Activates Intestinal Lysosomes to Improve Proteostasis in C. elegans
Soudabeh Imanikia et al.
CURRENT BIOLOGY (2019)
GABA receptors differentially regulate life span and health span in C. elegans through distinct downstream mechanisms
Fengling Yuan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2019)
Neuropeptides in Alzheimer's Disease: An Update
Carla Petrella et al.
CURRENT ALZHEIMER RESEARCH (2019)
Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans
Yue Zhang et al.
ELIFE (2019)
TOR Signaling in Caenorhabditis elegans Development, Metabolism, and Aging
T. Keith Blackwell et al.
GENETICS (2019)
Neuropeptides Exert Neuroprotective Effects in Alzheimer's Disease
Xin-Yi Chen et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)
Homeodomain-interacting protein kinase phosphorylates the Drosophila Paired box protein 6 (Pax6) homologues Twin of eyeless and Eyeless
E. L. Steinmetz et al.
INSECT MOLECULAR BIOLOGY (2018)
The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan
Adam B. Cornwel et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2018)
The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling
Qian Zhang et al.
CELL (2018)
Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression
Rachel Kaletsky et al.
PLOS GENETICS (2018)
Mutations in the guanylate cyclase gcy-28 neuronally dissociate naive attraction and memory retrieval
Naijin Li et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2018)
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
Xin-Xuan Lin et al.
NATURE COMMUNICATIONS (2018)
Single-cell RNA sequencing technologies and bioinformatics pipelines
Byungjin Hwang et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2018)
Hyperglycemia triggers HIPK2 protein degradation
Silvia Baldari et al.
ONCOTARGET (2017)
Shaping proteostasis at the cellular, tissue, and organismal level
Ambre J. Sala et al.
JOURNAL OF CELL BIOLOGY (2017)
Young Human Cholinergic Neurons Respond to Physiological Regulators and Improve Cognitive Symptoms in an Animal Model of Alzheimer's Disease
Annamaria Morelli et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2017)
Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans
Caroline Kumsta et al.
NATURE COMMUNICATIONS (2017)
The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1restricted autophagy in Caenorhabditis elegans
Ritika Das et al.
PLOS GENETICS (2017)
Aldicarb-induced Paralysis Assay to Determine Defects in Synaptic Transmission in Caenorhabditis elegans
Kelly H. Oh et al.
BIO-PROTOCOL (2017)
From the research laboratory to the database: the Caenorhabditis elegans kinome in UniProtKB
Rossana Zaru et al.
BIOCHEMICAL JOURNAL (2017)
Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis
Kristen M. Berendzen et al.
CELL (2016)
Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis
Sebum Lee et al.
NEURON (2016)
Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals
Shuhei Nakamura et al.
NATURE COMMUNICATIONS (2016)
Homeodomain-Interacting Protein Kinase (HPK-1) regulates stress responses and ageing in C. elegans
Slavica Berber et al.
SCIENTIFIC REPORTS (2016)
A cellular and regulatory map of the GABAergic nervous system of C. elegans
Marie Gendrel et al.
ELIFE (2016)
The Biology of Proteostasis in Aging and Disease
Johnathan Labbadia et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)
Transcriptional and epigenetic regulation of autophagy in aging
Louis R. Lapierre et al.
AUTOPHAGY (2015)
Neuronal Serotonin Release Triggers the Heat Shock Response in C. elegans in the Absence of Temperature Increase
Marcus C. Tatum et al.
CURRENT BIOLOGY (2015)
The Opposing Actions of Target of Rapamycin and AMP-Activated Protein Kinase in Cell Growth Control
Sravanth K. Hindupur et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
Metabotropic GABA signalling modulates longevity in C-elegans
Lei Chun et al.
NATURE COMMUNICATIONS (2015)
Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity
Peter M. Douglas et al.
CELL REPORTS (2015)
A gene-expression-based neural code for food abundance that modulates lifespan
Eugeni V. Entchev et al.
ELIFE (2015)
Hypoxia disrupts proteostasis in Caenorhabditis elegans
Emily M. Fawcett et al.
AGING CELL (2015)
Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity
Collin Y. Ewald et al.
NATURE (2015)
MDL-1, a growth- and tumor-suppressor, slows aging and prevents germline hyperplasia and hypertrophy in C. elegans
Michele Riesen et al.
AGING-US (2014)
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
Yang Liao et al.
BIOINFORMATICS (2014)
Trimmomatic: a flexible trimmer for Illumina sequence data
Anthony M. Bolger et al.
BIOINFORMATICS (2014)
Impaired proteostasis: role in the pathogenesis of diabetes mellitus
Stephane Jaisson et al.
DIABETOLOGIA (2014)
Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition
Ronak Lakhani et al.
EMBO MOLECULAR MEDICINE (2014)
Neuronal Vesicular Trafficking and Release in Age-Related Cognitive Impairment
Ferenc Deak
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
The Caenorhabditis elegans Myc-Mondo/Mad Complexes Integrate Diverse Longevity Signals
David W. Johnson et al.
PLOS GENETICS (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
STAR: ultrafast universal RNA-seq aligner
Alexander Dobin et al.
BIOINFORMATICS (2013)
XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity
Rebecca C. Taylor et al.
CELL (2013)
Homeodomain Interacting Protein Kinase (HPK-1) is Required in the Soma for Robust Germline Proliferation in C. elegans
Slavica Berber et al.
DEVELOPMENTAL DYNAMICS (2013)
Alzheimer's disease: An update of the roles of receptors, astrocytes and primary cilia (Review)
Ubaldo Armato et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2013)
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
Eyleen J. O'Rourke et al.
NATURE CELL BIOLOGY (2013)
The Caenorhabditis elegans Lifespan Machine
Nicholas Stroustrup et al.
NATURE METHODS (2013)
Glucose restriction induces cell death in parental but not in homeodomain-interacting protein kinase 2-depleted RKO colon cancer cells: molecular mechanisms and implications for tumor therapy
A. Garufi et al.
CELL DEATH & DISEASE (2013)
The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans
Louis R. Lapierre et al.
NATURE COMMUNICATIONS (2013)
Neuronal Reprograming of Protein Homeostasis by Calcium-Dependent Regulation of the Heat Shock Response
M. Catarina Silva et al.
PLOS GENETICS (2013)
Reduction of the immunostainable length of the hippocampal dentate granule cells' primary cilia in 3xAD-transgenic mice producing human Aβ1-42 and tau
Balu Chakravarthy et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Depletion of homeodomain-interacting protein kinase 3 impairs insulin secretion and glucose tolerance in mice
N. Shojima et al.
DIABETOLOGIA (2012)
A Redox-Regulated SUMO/Acetylation Switch of HIPK2 Controls the Survival Threshold to Oxidative Stress
Laureano de la Vega et al.
MOLECULAR CELL (2012)
Dopamine Signaling Is Essential for Precise Rates of Locomotion by C. elegans
Daniel T. Omura et al.
PLOS ONE (2012)
Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks
Robi Tacutu et al.
PLOS ONE (2012)
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Bo Li et al.
BMC BIOINFORMATICS (2011)
The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity
Jenni Durieux et al.
CELL (2011)
Behavioral Choice between Conflicting Alternatives Is Regulated by a Receptor Guanylyl Cyclase, GCY-28, and a Receptor Tyrosine Kinase, SCD-2, in AIA Interneurons of Caenorhabditis elegans
Yoichi Shinkai et al.
JOURNAL OF NEUROSCIENCE (2011)
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
Fabian Sievers et al.
MOLECULAR SYSTEMS BIOLOGY (2011)
Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins
Veena Prahlad et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Aging as an Event of Proteostasis Collapse
Rebecca C. Taylor et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
The Homeobox Protein CEH-23 Mediates Prolonged Longevity in Response to Impaired Mitochondrial Electron Transport Chain in C. elegans
Ludivine Walter et al.
PLOS BIOLOGY (2011)
Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation
Shilpa M. Hattangadi et al.
BLOOD (2010)
A cellular perspective on conformational disease: the role of genetic background and proteostasis networks
Tali Gidalevitz et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2010)
MEDICAL PROGRESS Williams-Beuren Syndrome
Barbara R. Pober
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Gene ontology analysis for RNA-seq: accounting for selection bias
Matthew D. Young et al.
GENOME BIOLOGY (2010)
Glucose Shortens the Life Span of C. elegans by Downregulating DAF-16/FOXO Activity and Aquaporin Gene Expression
Seung-Jae Lee et al.
CELL METABOLISM (2009)
The HIF-1 Hypoxia-Inducible Factor Modulates Lifespan in C. elegans
Yi Zhang et al.
PLOS ONE (2009)
HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans
Di Chen et al.
PLOS GENETICS (2009)
HIPKs: Jack of all trades in basic nuclear activities
Cinzia Rinaldo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
Yeast Yak1 kinase, a bridge between PKA and stress-responsive transcription factors, Hsf1 and Msn2/Msn4
Peter Lee et al.
MOLECULAR MICROBIOLOGY (2008)
A Behavioral switch: cGMP and PKC signaling in olfactory neurons reverses odor preference in C. elegans
Makoto Tsunozaki et al.
NEURON (2008)
A role for autophagy in the extension of lifespan by dietary restriction in C-elegans
Malene Hansen et al.
PLOS GENETICS (2008)
A Novel Role for the SMG-1 Kinase in Lifespan and Oxidative Stress Resistance in Caenorhabditis elegans
Ingrid Masse et al.
PLOS ONE (2008)
Regulation of the cellular heat shock response in Caenorhabditis elegans by thermosensory neurons
Veena Prahlad et al.
SCIENCE (2008)
Adapting proteostasis for disease intervention
William E. Balch et al.
SCIENCE (2008)
An antidepressant that extends lifespan in adult Caenorhabditis elegans
Michael Petrascheck et al.
NATURE (2007)
Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants
Andrew V. Samuelson et al.
GENES & DEVELOPMENT (2007)
Neuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells
Susana M. Garcia et al.
GENES & DEVELOPMENT (2007)
A C-elegans Myc-like network cooperates with semaphorin and Wnt signaling pathways to control cell migration
Christopher L. Pickett et al.
DEVELOPMENTAL BIOLOGY (2007)
HIPK2: a multitalented partner for transcription factors in DNA damage response and development
Cinzia Rinaldo et al.
BIOCHEMISTRY AND CELL BIOLOGY (2007)
Serotonin receptors antagonistically modulate Caenorhabditis elegans longevity
Hana Murakami et al.
AGING CELL (2007)
Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans
Kally Z. Pan et al.
AGING CELL (2007)
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
Malene Hansen et al.
AGING CELL (2007)
HIPK2 - a versatile switchboard regulating the transcription machinery and cell death
Marco A. Calzado et al.
CELL CYCLE (2007)
Essential function of HIPK2 in TGF beta-dependent survival of midbrain dopamine neurons
Jiasheng Zhang et al.
NATURE NEUROSCIENCE (2007)
Polyglutamine proteins at the pathogenic threshold display neuron-specific aggregation in a pan-neuronal Caenorhabditis elegans model
Heather R. Brignull et al.
JOURNAL OF NEUROSCIENCE (2006)
Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2
EA Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Progressive disruption of cellular protein folding in models of polyglutamine diseases
T Gidalevitz et al.
SCIENCE (2006)
PDSM, a motif for phosphorylation-dependent SUMO modification
V Hietakangas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Analysis of synaptic transmission in Caenorhabditis elegans using an aldicarb-sensitivity assay
Timothy R. Mahoney et al.
NATURE PROTOCOLS (2006)
A systematic RNAi screen for longevity genes in C-elegans
B Hamilton et al.
GENES & DEVELOPMENT (2005)
Expression profiling of GABAergic motor neurons in Caenorhabditis elegans
H Cinar et al.
CURRENT BIOLOGY (2005)
Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones
JF Morley et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
GenAge: a genomic and proteomic network map of human ageing
JP de Magalhaes et al.
FEBS LETTERS (2004)
Intraflagellar transport motors in Caenorhabditis elegans neurons
JM Scholey et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2004)
The Gene Ontology (GO) database and informatics resource
MA Harris et al.
NUCLEIC ACIDS RESEARCH (2004)
Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans
C Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Role of the ASK1-SEK1-JNK1-HIPK1 signal in Daxx trafficking and ASK1 oligomerization
JJ Song et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy
BC Kraemer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
SKN-1 links C-elegans mesendodermal specification to a conserved oxidative stress response
JH An et al.
GENES & DEVELOPMENT (2003)
Effect of glucose concentration on activation of the ASK1-SEK1-JNK1 signal transduction pathway
JJ Song et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2003)
DAF-16 target genes that control C-elegans life-span and metabolism
SS Lee et al.
SCIENCE (2003)
Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1
V Hietakangas et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity
JA Ecsedy et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Stochastic and genetic factors influence tissue-specific decline in ageing C-elegans
LA Herndon et al.
NATURE (2002)
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
JF Morley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Serotonin modulates locomotory behavior and coordinates egg-laying and movement in Caenorhabditis elegans
LA Hardaker et al.
JOURNAL OF NEUROBIOLOGY (2001)
Food and metabolic signaling defects in a Caenorhabditis elegans serotonin-synthesis mutant
JY Sze et al.
NATURE (2000)
KEGG: Kyoto Encyclopedia of Genes and Genomes
M Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2000)