Journal
ASIAN JOURNAL OF ORGANIC CHEMISTRY
Volume -, Issue -, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ajoc.202300182
Keywords
Pd-catalyzed; carboamination reaction; alkenyl hydrazones; aryl triflates; dihydropyrazoles
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In this study, a novel and efficient strategy for the synthesis of dihydropyrazoles was presented. The synthesis involved the Pd-catalyzed carboamination reaction of alkenyl hydrazones with aryl triflates, leading to the simultaneous formation of C-C and C-N bonds. This methodology offers a practical and efficient approach for the synthesis of diversely aryl substituted dihydropyrazoles in good yields.
Herein, we presented a novel and highly efficient strategy for the synthesis of dihydropyrazoles via Pd-catalyzed carboamination reaction of alkenyl hydrazones with aryl triflates. The simultaneous formation of C-C and C-N bonds in one step is particularly appealing. This methodology provides a practical and efficient avenue of the synthesis of diversely aryl substituted dihydropyrazoles in good yields.
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