Synthesis of Dihydropyrazoles by Pd-Catalyzed Carboamination of Alkenyl Hydrazones with Aryl Triflates

Herein, we presented a novel and highly efficient strategy for the synthesis of dihydropyrazoles via Pd-catalyzed carboamination reaction of alkenyl hydrazones with aryl triflates. The simultaneous formation of C-C and C-N bonds in one step is particularly appealing. This methodology provides a practical and efficient avenue of the synthesis of diversely aryl substituted dihydropyrazoles in good yields.

Automated summary

In this study, a novel and efficient strategy for the synthesis of dihydropyrazoles was presented. The synthesis involved the Pd-catalyzed carboamination reaction of alkenyl hydrazones with aryl triflates, leading to the simultaneous formation of C-C and C-N bonds. This methodology offers a practical and efficient approach for the synthesis of diversely aryl substituted dihydropyrazoles in good yields.