Journal
LAB ON A CHIP
Volume 16, Issue 9, Pages 1561-1564Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5lc01498k
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Funding
- German Ministry of Education and Research (BMBF) [03X5527]
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Cyclic olefin copolymer (COC) is widely used in microfluidics due to its UV-transparency, its biocompatibility and high chemical resistance. Here we present a fast and cost-effective solvent bonding technique, which allows for the efficient bonding of protein-patterned COC structures. The bonding process is carried out at room temperature and takes less than three minutes. Enzyme activity is retained upon bonding and microstructure deformation does not occur.
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