Synthesis, Characterization, Properties, and Biomedical Application of Chitosan-Based Hydrogels

The prospective applications of chitosan-based hydrogels (CBHs), a category of biocompatible and biodegradable materials, in biomedical disciplines such as tissue engineering, wound healing, drug delivery, and biosensing have garnered great interest. The synthesis and characterization processes used to create CBHs play a significant role in determining their characteristics and effectiveness. The qualities of CBHs might be greatly influenced by tailoring the manufacturing method to get certain traits, including porosity, swelling, mechanical strength, and bioactivity. Additionally, characterization methods aid in gaining access to the microstructures and properties of CBHs. Herein, this review provides a comprehensive assessment of the state-of-the-art with a focus on the affiliation between particular properties and domains in biomedicine. Moreover, this review highlights the beneficial properties and wide application of stimuli-responsive CBHs. The main obstacles and prospects for the future of CBH development for biomedical applications are also covered in this review.

Automated summary

The potential applications of chitosan-based hydrogels (CBHs) in biomedical fields such as tissue engineering, wound healing, drug delivery, and biosensing have attracted great interest. The synthesis and characterization methods used to create CBHs play a crucial role in determining their properties and effectiveness. Tailoring the manufacturing process can greatly influence the qualities of CBHs, including porosity, swelling, mechanical strength, and bioactivity. Characterization methods are also important in understanding the microstructures and properties of CBHs. This review provides a comprehensive assessment of the current state-of-the-art, focusing on the relationship between specific properties and biomedical domains. It also highlights the beneficial properties and wide application of stimuli-responsive CBHs, as well as discussing the main obstacles and future prospects for CBH development in biomedical applications.