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Metal-Organic Frameworks Applications in Synergistic Cancer Photo-Immunotherapy

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Application of smart nanoparticles as a potential platform for effective colorectal cancer therapy

Sonia Iranpour et al.

Summary: Nanomedicine combines nanotechnology and medicine to enhance the safety and efficacy of therapeutic agents for disease diagnosis and treatment. In the field of colorectal cancer therapy, mesoporous silica nanoparticles, superparamagnetic iron oxide nanoparticles, and metal organic frameworks have been utilized as inorganic nanocarriers. However, challenges remain in maximizing the therapeutic index when using these nanocarriers for cancer treatment.

COORDINATION CHEMISTRY REVIEWS (2021)

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Review Nanoscience & Nanotechnology

CpG-Based Nanovaccines for Cancer Immunotherapy

Wenqiang Chen et al.

Summary: Nanoparticles used as carriers and/or adjuvants in tumor vaccines have shown significant therapeutic effects in cancer treatment. CpG ODN, a commonly used immune stimulant, can activate humoral and cellular immunity through Toll-like receptor 9 for cancer prevention or treatment.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

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Article Chemistry, Multidisciplinary

Photothermal-Chemotherapy Enhancing Tumor Immunotherapy by Multifunctional Metal-Organic Framework Based Drug Delivery System

Weidong Ni et al.

Summary: Immunotherapy shows promise for tumor treatment, but its clinical effect is limited by tumor immunogenicity and the immunosuppressive microenvironment. Researchers combined metal-organic framework MIL-100 loaded with mitoxantrone (MTO) with photothermal-chemotherapy to enhance immunogenic cell death. The resulting MMH NPs, with dual therapeutic properties and imaging modes, showed high antitumor efficacy and immune effect when co-injected with anti-OX40 antibody in colorectal cancer. This novel combined therapeutic strategy is promising for future tumor therapy.

NANO LETTERS (2021)

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Article Chemistry, Physical

Metal-Organic Frameworks (MOFs)-Based Nanomaterials for Drug Delivery

Mohammad Reza Saeb et al.

Summary: Metal-organic frameworks (MOFs), especially nanoscale MOFs (NMOFs), show exceptional tailorable properties and high potential for carrying anticancer drugs. Compared to other delivery systems, NMOFs are more flexible, have higher biodegradability potential, and can be easily functionalized.

MATERIALS (2021)

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Article Engineering, Biomedical

An Engineered Prussian Blue Nanoparticles-Based Nanoimmunotherapy Elicits Robust and Persistent Immunological Memory in a TH-MYCN Neuroblastoma Model

Anshi Shukla et al.

Summary: The CpG-PBNP-PTT nanoimmunotherapy shows efficacy in triggering immunogenic cell death in vitro and generating complete tumor regression in vivo, leading to improved long-term survival in a murine NB model. Furthermore, the treatment generates robust T cell-mediated immunological memory and slows tumor progression in untreated areas, demonstrating therapeutic implications for solid tumors like NB.

ADVANCED NANOBIOMED RESEARCH (2021)

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Review Engineering, Biomedical

Advances in Functional Metal-Organic Frameworks Based On-Demand Drug Delivery Systems for Tumor Therapeutics

Bhanu Nirosha Yalamandala et al.

Summary: Hybrid materials like MOFs show promise in tumor therapy by enabling precise drug release and energy delivery, including thermal or dynamic therapy. Overcoming tumor heterogeneity and leveraging innate immune system are crucial for the clinical translation of MOFs, requiring further comprehensive studies and strategies.

ADVANCED NANOBIOMED RESEARCH (2021)

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Review Chemistry, Physical

Revisiting the MIL-101 metal-organic framework: design, synthesis, modifications, advances, and recent applications

Mahmoud Y. Zorainy et al.

Summary: Metal-organic frameworks (MOFs) have become a burgeoning topic in materials science and engineering, with success attributed to the diversity and precise control of their structures. This study critically reviews the design and synthesis of MIL-101 MOFs, including different metal analogues, synthesis strategies, and applications. The influence of synthesis parameters on final product characteristics is discussed, along with the detection of various polymorphs in the framework structures. Recent applications of MIL-101 in adsorption, catalysis, sensor design, and drug delivery are also presented and discussed.

JOURNAL OF MATERIALS CHEMISTRY A (2021)

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Review Nanoscience & Nanotechnology

Phototherapy meets immunotherapy: a win-win strategy to fight against cancer

Jianhua Zou et al.

Summary: Phototherapy combined with immunotherapy enhances the immunostimulating response and has synergistic effects for cancer treatment. Photoimmunotherapy (PIT) is a potential win-win strategy to prevent tumor metastases and recurrence by inducing immunogenic cell death (ICD).

NANOPHOTONICS (2021)

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Review Medicine, Research & Experimental

Recent strategies for nano-based PTT combined with immunotherapy: from a biomaterial point of view

Xingyue Huang et al.

Summary: The review summarized cutting-edge strategies in combining nano-based photothermal therapy (PTT) with immunotherapy for cancer treatment, which includes four categories of combination strategies. Various photothermal agents and nanoplatforms characteristics, as well as the immunological mechanisms for the synergism, were introduced in detail. Existing challenges and future prospects in combined PTT and immunotherapy were also discussed.

THERANOSTICS (2021)

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Review Chemistry, Multidisciplinary

Supramolecular agents for combination of photodynamic therapy and other treatments

Nahyun Kwon et al.

Summary: Photodynamic therapy (PDT) shows promise in treating various cancers, but its therapeutic benefits are limited by oxygen dependence and inadequate light permeability. Recent advancements in supramolecular approaches have led to the development of multifunctional supramolecular photosensitizer assemblies that combine PDT with other therapies to achieve synergistic effects and maximize treatment outcomes.

CHEMICAL SCIENCE (2021)

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Review Chemistry, Multidisciplinary

Nanoscale metal-organic framework composites for phototherapy and synergistic therapy of cancer

Zhihong Bao et al.

Summary: Phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), has gained significant attention for its high spatial selectivity and non-invasiveness. Nanoscale metal-organic frameworks (nMOFs) are ideal for biomedical applications, especially in cancer phototherapy, due to their unique characteristics.

MATERIALS CHEMISTRY FRONTIERS (2021)

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Review Medicine, Research & Experimental

Cancer photo-immunotherapy: from bench to bedside

Miao Wang et al.

Summary: The combination of targeted therapy and immunotherapy is considered an ideal strategy for treating metastatic cancer, with phototherapy emerging as a promising targeted therapy that can initiate antitumor immune responses through induced immunogenic tumor cell death. The use of phototherapy in conjunction with immunoadjuvant therapy has shown to induce a systemic antitumor immune response, controlling residual tumor cells at the treatment site and distant metastases.

THERANOSTICS (2021)

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Article Chemistry, Multidisciplinary

A Nanoscale Metal-Organic Framework to Mediate Photodynamic Therapy and Deliver CpG Oligodeoxynucleotides to Enhance Antigen Presentation and Cancer Immunotherapy

Kaiyuan Ni et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

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Article Engineering, Biomedical

Photodynamic Therapy Combined with Antihypoxic Signaling and CpG Adjuvant as an In Situ Tumor Vaccine Based on Metal-Organic Framework Nanoparticles to Boost Cancer Immunotherapy

Zhixiong Cai et al.

ADVANCED HEALTHCARE MATERIALS (2020)

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Article Chemistry, Multidisciplinary

Increasing the Potential Interacting Area of Nanomedicine Enhances Its Homotypic Cancer Targeting Efficacy

Jingyi Zhu et al.

ACS NANO (2020)

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Review Engineering, Biomedical

Metal-organic frameworks for stimuli-responsive drug delivery

Ying Wang et al.

BIOMATERIALS (2020)

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Review Chemistry, Multidisciplinary

Recent progress in tumor photodynamic immunotherapy

Lijun Shen et al.

CHINESE CHEMICAL LETTERS (2020)

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Article Chemistry, Multidisciplinary

Engineering of Upconverted Metal-Organic Frameworks for Near-Infrared Light-Triggered Combinational Photodynamic/Chemo-/Immunotherapy against Hypoxic Tumors

Yulei Shao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

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Review Chemistry, Multidisciplinary

Metal-Organic Frameworks for Biomedical Applications

Jie Yang et al.

SMALL (2020)

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Article Nanoscience & Nanotechnology

One Stone Two Birds: Zr-Fc Metal-Organic Framework Nanosheet for Synergistic Photothermal and Chemodynamic Cancer Therapy

Zheng Deng et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Nanoscience & Nanotechnology

Treating Immunologically Cold Tumors by Precise Cancer Photoimmunotherapy with an Extendable Nanoplatform

Wenqian Yu et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Engineering, Biomedical

Site-specific MOF-based immunotherapeutic nanoplatforms via synergistic tumor cells-targeted treatment and dendritic cells-targeted immunomodulation

Huiyuan Zhang et al.

BIOMATERIALS (2020)

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Article Engineering, Biomedical

Near infrared light-triggered metal ion and photodynamic therapy based on AgNPs/porphyrinic MOFs for tumors and pathogens elimination

Lu Zhang et al.

BIOMATERIALS (2020)

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Article Chemistry, Multidisciplinary

Penetrable Nanoplatform for Cold Tumor Immune Microenvironment Reeducation

Qinjun Chen et al.

ADVANCED SCIENCE (2020)

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Review Chemistry, Multidisciplinary

Nanoscale Metal-Organic Frameworks for Cancer Immunotherapy

Kaiyuan Ni et al.

ACCOUNTS OF CHEMICAL RESEARCH (2020)

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Article Chemistry, Multidisciplinary

A Hepatocellular Carcinoma Targeting Nanostrategy with Hypoxia-Ameliorating and Photothermal Abilities that, Combined with Immunotherapy, Inhibits Metastasis and Recurrence

Tianjun Zhou et al.

ACS NANO (2020)

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Article Chemistry, Multidisciplinary

Programmable Delivery of Immune Adjuvant to Tumor-Infiltrating Dendritic Cells for Cancer Immunotherapy

Jing Liu et al.

NANO LETTERS (2020)

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Review Chemistry, Multidisciplinary

Destruction of Metal-Organic Frameworks: Positive and Negative Aspects of Stability and Lability

Liang Feng et al.

CHEMICAL REVIEWS (2020)

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Article Oncology

CpG-coated prussian blue nanoparticles-based photothermal therapy combined with anti-CTLA-4 immune checkpoint blockade triggers a robust abscopal effect against neuroblastoma

Juliana Cano-Mejia et al.

TRANSLATIONAL ONCOLOGY (2020)

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Review Engineering, Multidisciplinary

Learning from Nature: Bioinspired Chlorin-Based Photosensitizers Immobilized on Carbon Materials for Combined Photodynamic and Photothermal Therapy

Lucas D. Dias et al.

BIOMIMETICS (2020)

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Review Chemistry, Multidisciplinary

Nanoparticle Phototherapy in the Era of Cancer Immunotherapy

Shiyi Zhou et al.

TRENDS IN CHEMISTRY (2020)

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Review Chemistry, Multidisciplinary

Emerging combination strategies with phototherapy in cancer nanomedicine

Zhongjian Xie et al.

CHEMICAL SOCIETY REVIEWS (2020)

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Review Oncology

Turning Cold into Hot: Firing up the Tumor Microenvironment

Qianqian Duan et al.

TRENDS IN CANCER (2020)

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Article Materials Science, Biomaterials

pH-Responsive metal-organic framework encapsulated gold nanoclusters with modulated release to enhance photodynamic therapy/chemotherapy in breast cancer

Luyun Zhang et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

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Article Chemistry, Multidisciplinary

Photothermal therapy-induced immunogenic cell death based on natural melanin nanoparticles against breast cancer

Yanhua Li et al.

CHEMICAL COMMUNICATIONS (2020)

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Review Immunology

Tumour-intrinsic resistance to immune checkpoint blockade

Anusha Kalbasi et al.

NATURE REVIEWS IMMUNOLOGY (2020)

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Article Biophysics

Bimetallic ZrHf-based metal-organic framework embedded with carbon dots: Ultra-sensitive platform for early diagnosis of HER2 and HER2-overexpressed living cancer cells

Chenxi Gu et al.

BIOSENSORS & BIOELECTRONICS (2019)

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Review Chemistry, Multidisciplinary

Two-dimensional cancer theranostic nanomaterials: Synthesis, surface functionalization and applications in photothermal therapy

Chandran Murugan et al.

JOURNAL OF CONTROLLED RELEASE (2019)

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Article Multidisciplinary Sciences

Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death

Wei Li et al.

NATURE COMMUNICATIONS (2019)

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Article Chemistry, Multidisciplinary

被撤回的出版物: Nanoscale Metal-Organic Framework Mediates Radical Therapy to Enhance Cancer Immunotherapy (Retracted article. See vol. 9, pg. 755, 2023)

Kaiyuan Ni et al.

CHEM (2019)

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Article Chemistry, Multidisciplinary

Nanozymes-Engineered Metal-Organic Frameworks for Catalytic Cascades-Enhanced Synergistic Cancer Therapy

Chuang Liu et al.

NANO LETTERS (2019)

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Review Chemistry, Multidisciplinary

Metal-organic framework structures: adsorbents for natural gas storage

Asian Yu Tsivadze et al.

RUSSIAN CHEMICAL REVIEWS (2019)

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Article Chemistry, Multidisciplinary

Dual Metal-Organic Framework Heterointerface

Yue Luo et al.

ACS CENTRAL SCIENCE (2019)

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Review Biochemistry & Molecular Biology

The Course of Immune Stimulation by Photodynamic Therapy: Bridging Fundamentals of Photochemically Induced Immunogenic Cell Death to the Enrichment of T-Cell Repertoire

Shubhankar Nath et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2019)

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Article Engineering, Biomedical

Gemcitabine nanoparticles promote antitumor immunity against melanoma

Yuan Zhang et al.

BIOMATERIALS (2019)

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Review Chemistry, Inorganic & Nuclear

Nanoscale metal-organic frameworks for phototherapy of cancer

Guangxu Lan et al.

COORDINATION CHEMISTRY REVIEWS (2019)

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Article Pharmacology & Pharmacy

Development of gelatin microsphere encapsulated Cu-based metal-organic framework nanohybrid for the methotrexate delivery

Parinaz Nezhad-Mokhtari et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2019)

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Review Materials Science, Multidisciplinary

Metal-organic frameworks: Structures and functional applications

Long Jiao et al.

MATERIALS TODAY (2019)

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Article Chemistry, Multidisciplinary

Metal Organic Framework-Based Stimuli-Responsive Systems for Drug Delivery

Wen Cai et al.

ADVANCED SCIENCE (2019)

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Article Chemistry, Multidisciplinary

Biomimetic Metal-Organic Framework Nanoparticles for Cooperative Combination of Antiangiogenesis and Photodynamic Therapy for Enhanced Efficacy

Huan Min et al.

ADVANCED MATERIALS (2019)

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Article Chemistry, Multidisciplinary

Hyaluronic Acid-Based Activatable Nanomaterials for Stimuli-Responsive Imaging and Therapeutics: Beyond CD44-Mediated Drug Delivery

Ki Young Choi et al.

ADVANCED MATERIALS (2019)

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Article Chemistry, Multidisciplinary

Expandable Immunotherapeutic Nanoplatforms Engineered from Cytomembranes of Hybrid Cells Derived from Cancer and Dendritic Cells

Wen-Long Liu et al.

ADVANCED MATERIALS (2019)

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Review Chemistry, Multidisciplinary

X-ray-activated nanosystems for theranostic applications

Xiaofeng Chen et al.

CHEMICAL SOCIETY REVIEWS (2019)

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Review Pharmacology & Pharmacy

Metal-Organic Framework Mediated Multifunctional Nanoplatforms for Cancer Therapy

Jin-Yue Zeng et al.

ADVANCED THERAPEUTICS (2019)

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Article Materials Science, Biomaterials

Harnessing combinational phototherapy via post-synthetic PpIX conjugation on nanoscale metal-organic frameworks

Rui Chen et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

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Article Chemistry, Inorganic & Nuclear

Functionalized Eu(III)-Based Nanoscale Metal-Organic Framework To Achieve Near-IR-Triggered and -Targeted Two-Photon Absorption Photodynamic Therapy

Jianguo Jia et al.

INORGANIC CHEMISTRY (2018)

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Article Chemistry, Multidisciplinary

Multifunctional Efficiency: Extending the Concept of Atom Economy to Functional Nanomaterials

Ralph Freund et al.

ACS NANO (2018)

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Review Chemistry, Multidisciplinary

Stable Metal-Organic Frameworks: Design, Synthesis, and Applications

Shuai Yuan et al.

ADVANCED MATERIALS (2018)

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Article Engineering, Biomedical

Biomimetic O2-Evolving metal-organic framework nanoplatform for highly efficient photodynamic therapy against hypoxic tumor

Shutao Gao et al.

BIOMATERIALS (2018)

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Article Oncology

Emerging Concepts for Immune Checkpoint Blockade-Based Combination Therapies

Roberta Zappasodi et al.

CANCER CELL (2018)

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Article Chemistry, Physical

Control of Structure Topology and Spatial Distribution of Biomacromolecules in Protein@ZIF-8 Biocomposites

Weibin Liang et al.

CHEMISTRY OF MATERIALS (2018)

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Review Immunology

Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors

Kristian M. Hargadon et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2018)

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Review Oncology

Next generation of immune checkpoint therapy in cancer: new developments and challenges

Julian A. Marin-Acevedo et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)

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Article Chemistry, Multidisciplinary

Nanoscale Metal-Organic Framework Overcomes Hypoxia for Photodynamic Therapy Primed Cancer Immunotherapy

Guangxu Lan et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

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Review Engineering, Biomedical

Progress in Applications of Prussian Blue Nanoparticles in Biomedicine

Zhiguo Qin et al.

ADVANCED HEALTHCARE MATERIALS (2018)

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Article Materials Science, Biomaterials

Albumin/sulfonamide stabilized iron porphyrin metal organic framework nanocomposites: targeting tumor hypoxia by carbonic anhydrase IX inhibition and T-1-T-2 dual mode MRI guided photodynamic/photothermal therapy

Wei Zhu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

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Review Immunology

The Role of indoleamine-2,3-Dioxygenase in Cancer Development, Diagnostics, and Therapy

Lilla Hornyak et al.

FRONTIERS IN IMMUNOLOGY (2018)

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Article Chemistry, Multidisciplinary

Improving the Mechanical Stability of Metal-Organic Frameworks Using Chemical Caryatids

Seyed Mohamad Moosavi et al.

ACS CENTRAL SCIENCE (2018)

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Article Chemistry, Multidisciplinary

Metal-Organic Framework Nanoshuttle for Synergistic Photodynamic and Low-Temperature Photothermal Therapy

Kai Zhang et al.

ADVANCED FUNCTIONAL MATERIALS (2018)

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Article Chemistry, Multidisciplinary

An all-in-one antitumor and anti-recurrence/metastasis nanomedicine with multi-drug co-loading and burst drug release for multi-modality therapy

Ji-Chun Yang et al.

CHEMICAL SCIENCE (2018)

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Article Nanoscience & Nanotechnology

Carbon Dots/Prussian Blue Satellite/Core Nanocomposites for Optical Imaging and Photothermal Therapy

Xinyi Peng et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

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Article Chemistry, Multidisciplinary

Mechanical Properties in Metal-Organic Frameworks: Emerging Opportunities and Challenges for Device Functionality and Technological Applications

Nicholas C. Burtch et al.

ADVANCED MATERIALS (2018)

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Article Nanoscience & Nanotechnology

Prussian blue nanoparticle-based photothermal therapy combined with checkpoint inhibition for photothermal immunotherapy of neuroblastoma

Juliana Cano-Mejia et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2017)

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Article Multidisciplinary Sciences

T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition

Enfu Hui et al.

SCIENCE (2017)

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Article Chemistry, Multidisciplinary

Grand Challenges and Future Opportunities for Metal-Organic Frameworks

Christopher H. Hendon et al.

ACS CENTRAL SCIENCE (2017)

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Article Oncology

Cancer Nanomedicine: Lessons for Immuno-Oncology

Shiladitya Sengupta

TRENDS IN CANCER (2017)

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Review Chemistry, Multidisciplinary

Advancing porphyrin's biomedical utility via supramolecular chemistry

M. A. Rajora et al.

CHEMICAL SOCIETY REVIEWS (2017)

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Article Chemistry, Physical

Exosome-Coated Metal-Organic Framework Nanoparticles: An Efficient Drug Delivery Platform

Bernhard Illes et al.

CHEMISTRY OF MATERIALS (2017)

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Review Pharmacology & Pharmacy

Delivering safer immunotherapies for cancer

Lauren Milling et al.

ADVANCED DRUG DELIVERY REVIEWS (2017)

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Article Chemistry, Multidisciplinary

Metal-Organic Framework Nanoparticles in Photodynamic Therapy: Current Status and Perspectives

Marjorie Lismont et al.

ADVANCED FUNCTIONAL MATERIALS (2017)

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Article Chemistry, Multidisciplinary

Cell Membrane Camouflaged Hollow Prussian Blue Nanoparticles for Synergistic Photothermal-/Chemotherapy of Cancer

Wansong Chen et al.

ADVANCED FUNCTIONAL MATERIALS (2017)

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Article Nanoscience & Nanotechnology

Multifunctional Metal-Organic Framework Nanoprobe for Cathepsin B-Activated Cancer Cell Imaging and Chemo-Photodynamic Therapy

Jintong Liu et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

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Article Chemistry, Multidisciplinary

Metal-Organic Framework/Graphene Quantum Dot Nanoparticles Used for Synergistic Chemo-and Photothermal Therapy

Zhengfang Tian et al.

ACS OMEGA (2017)

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Review Immunology

Immunogenic cell death in cancer and infectious disease

Lorenzo Galluzzi et al.

NATURE REVIEWS IMMUNOLOGY (2017)

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Article Nanoscience & Nanotechnology

Engineering Phototheranostic Nanoscale Metal-Organic Frameworks for Multimodal Imaging-Guided Cancer Therapy

Wen Cai et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

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Article Nanoscience & Nanotechnology

PPy@MIL-100 Nanoparticles as a pH- and Near-IR-Irradiation-Responsive Drug Carrier for Simultaneous Photothermal Therapy and Chemotherapy of Cancer Cells

Yu-Da Zhu et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

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Article Chemistry, Multidisciplinary

Nanoscale Metal-Organic Particles with Rapid Clearance for Magnetic Resonance Imaging-Guided Photothermal Therapy

Yu Yang et al.

ACS NANO (2016)

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Article Chemistry, Multidisciplinary

Metal-Organic-Framework-Based Vaccine Platforms for Enhanced Systemic Immune and Memory Response

Yan Zhang et al.

ADVANCED FUNCTIONAL MATERIALS (2016)

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Review Chemistry, Multidisciplinary

Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

Zijian Zhou et al.

CHEMICAL SOCIETY REVIEWS (2016)

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Article Chemistry, Multidisciplinary

Size-Controlled Synthesis of Porphyrinic Metal-Organic Framework and Functionalization for Targeted Photodynamic Therapy

Jihye Park et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

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Article Chemistry, Multidisciplinary

Chlorin-Based Nanoscale Metal-Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy

Kuangda Lu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

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Article Medicine, Research & Experimental

Gemcitabine reduces MDSCs, tregs and TGFβ-1 while restoring the teff/treg ratio in patients with pancreatic cancer

Emma Eriksson et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2016)

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Review Cell Biology

PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

Weiping Zou et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

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Review Chemistry, Multidisciplinary

Cancer-Targeted Nanotheranostics: Recent Advances and Perspectives

Yufei Ma et al.

SMALL (2016)

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Review Nanoscience & Nanotechnology

Chemical, thermal and mechanical stabilities of metal-organic frameworks

Ashlee J. Howarth et al.

NATURE REVIEWS MATERIALS (2016)

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Article Developmental Biology

Immunogenic cell death

Abhishek D. Garg et al.

INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2015)

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Review Chemistry, Multidisciplinary

Nanocomposite-Based Photodynamic Therapy Strategies for Deep Tumor Treatment

Jun Hu et al.

SMALL (2015)

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Review Pharmacology & Pharmacy

HIF-1α pathway: role, regulation and intervention for cancer therapy

Georgina N. Masoud et al.

ACTA PHARMACEUTICA SINICA B (2015)

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Review Biochemistry & Molecular Biology

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

L. Galluzzi et al.

CELL DEATH AND DIFFERENTIATION (2015)

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Article Chemistry, Multidisciplinary

Topology-Guided Design and Syntheses of Highly Stable Mesoporous Porphyrinic Zirconium Metal-Organic Frameworks with High Surface Area

Tian-Fu Liu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

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Review Chemistry, Multidisciplinary

Structuring of metal-organic frameworks at the mesoscopic/macroscopic scale

Shuhei Furukawa et al.

CHEMICAL SOCIETY REVIEWS (2014)

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Article Chemistry, Multidisciplinary

Nanoscale Metal-Organic Framework for Highly Effective Photodynamic Therapy of Resistant Head and Neck Cancer

Kuangda Lu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

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Article Chemistry, Multidisciplinary

Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

Ronnie H. Fang et al.

NANO LETTERS (2014)

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Review Multidisciplinary Sciences

The Chemistry and Applications of Metal-Organic Frameworks

Hiroyasu Furukawa et al.

SCIENCE (2013)

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Review Biochemistry & Molecular Biology

Autophagy and mitophagy in cellular damage control

Jianhua Zhang

REDOX BIOLOGY (2013)

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Review Biochemistry & Molecular Biology

Non Polymeric Nanoparticles for Photodynamic Therapy Applications: Recent Developments

R. Chouikrat et al.

CURRENT MEDICINAL CHEMISTRY (2012)

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Review Oncology

The blockade of immune checkpoints in cancer immunotherapy

Drew M. Pardoll

NATURE REVIEWS CANCER (2012)

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Review Multidisciplinary Sciences

Cancer immunotherapy comes of age

Ira Mellman et al.

NATURE (2011)

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Review Cell Biology

Mechanisms of mitophagy

Richard J. Youle et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)

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Review Immunology

IL-6: Regulator of Treg/Th17 balance

Akihiro Kimura et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2010)

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Review Chemistry, Multidisciplinary

Metal-organic framework structures - how closely are they related to classical inorganic structures?

Srinivasan Natarajan et al.

CHEMICAL SOCIETY REVIEWS (2009)

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Review Biochemistry & Molecular Biology

Photodynamic therapy (PDT): A short review on cellular mechanisms and cancer research applications for PDT

C. A. Robertson et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2009)

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Article Multidisciplinary Sciences

Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization

KangAe Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

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Review Oncology

Application of nanotechnology in cancer therapy and imaging

Xu Wang et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2008)

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Article Medicine, General & Internal

Sorafenib in advanced hepatocellular carcinoma

Josep M. Llovet et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

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Article Multidisciplinary Sciences

A chromium terephthalate-based solid with unusually large pore volumes and surface area

G Férey et al.

SCIENCE (2005)

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Article Multidisciplinary Sciences

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

CM Revankar et al.

SCIENCE (2005)

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Review Chemistry, Multidisciplinary

Reticular chemistry: Occurrence and taxonomy of nets and grammar for the design of frameworks

NW Ockwig et al.

ACCOUNTS OF CHEMICAL RESEARCH (2005)

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Review Chemistry, Inorganic & Nuclear

Photosensitized singlet oxygen and its applications

MC DeRosa et al.

COORDINATION CHEMISTRY REVIEWS (2002)

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