Journal
POLYMERS
Volume 15, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/polym15061423
Keywords
laser direct writing; enzyme-free glucose sensor; silver particles; glucose-responsive; hydrogels
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A silver-doped Concanavalin A (Con A)-based hydrogel sensor is proposed as an ideal continuous glucose monitoring system for diabetic patients. It demonstrates good glucose-responsive ability and high linearity within a large detection range, making it excellent among existing enzyme-free glucose sensors.
A continuous glucose monitoring (CGM) system is an ideal monitoring system for the blood glucose control of diabetic patients. The development of flexible glucose sensors with good glucose-responsive ability and high linearity within a large detection range is still challenging in the field of continuous glucose detection. A silver-doped Concanavalin A (Con A)-based hydrogel sensor is proposed to address the above issues. The proposed flexible enzyme-free glucose sensor was prepared by combining Con-A-based glucose-responsive hydrogels with green-synthetic silver particles on laser direct-writing graphene electrodes. The experimental results showed that in a glucose concentration range of 0-30 mM, the proposed sensor is capable of measuring the glucose level in a repeatable and reversible manner, showing a sensitivity of 150.12 omega/mM with high linearity of R-2 = 0.97. Due to its high performance and simple manufacturing process, the proposed glucose sensor is excellent among existing enzyme-free glucose sensors. It has good potential in the development of CGM devices.
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