Journal
MEDIZINISCHE KLINIK-INTENSIVMEDIZIN UND NOTFALLMEDIZIN
Volume 118, Issue 2, Pages 107-113Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00063-023-00993-1
Keywords
Pathologic processes; Dysbiosis; Inflammation; High-throughput nucleotide sequencing; Fecal microbiota transplantation
Categories
Ask authors/readers for more resources
The gut microbiota, consisting of over 1200 different bacteria, forms a symbiotic relationship with the human organism. It plays a crucial role in maintaining homeostasis of the immune system and essential metabolic processes. This article summarizes recent findings on the role of the bacterial gut microbiota in sepsis, which is highly relevant in intensive care medicine.
The gut microbiota is comprised of over 1200 different bacteria and forms a symbiotic community with the human organism, the holobiont. It plays an important role in the maintenance of homeostasis, e.g., of the immune system and essential metabolic processes. Disturbances in the balance of this reciprocal relationship are called dysbiosis and, in the field of sepsis, are associated with incidence of disease, extent of the systemic inflammatory response, severity of organ dysfunction, and mortality. In addition to providing guiding principles in the fascinating relationship between human and microbe, this article summarizes recent findings regarding the role of the bacterial gut microbiota in sepsis, which is one a very relevant in intensive care medicine.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available