Cytokine expression in gingival crevicular fluid around teeth opposing dental implants and 3-unit fixed partial dentures in a cross-sectional study

ObjectiveThis study aimed to study the cytokines in gingival crevicular fluid (GCF) of the teeth opposing to dental implants and 3-unit fixed partial dentures (FPDs).Materials and methodsA total of 74 participants were recruited for this cross-sectional study. Based on the status of lower first molars, the participants were divided into dental implants group and 3-unit FPDs group. Social index and oral hygiene were recorded. Occlusal loading was evaluated with a T-scan. GCF was sampled from the upper first molar and assessed with a commercial cytokine assay kit.ResultsForty three dental implants patients and 31 3-unit FPDs patients received all of the clinical and laboratory evaluation. The dental implants group had a higher occlusion force distribution on first molars region. IL-10, IL-17, RANK had a higher mean in dental implants group and was associated with occlusion force of first molar. There was a weakly association between IL-10 and dental implants in the binary logistic regression analyses.ConclusionsIn this study, the teeth opposing implants have a higher level of cytokines in the GCF than teeth opposing to 3-unit FPDs in periodontal healthy participants because of the poor osseoperception of dental implants. IL-10 might reflect a higher occlusion force in dental implants region.

Automated summary

This study aimed to investigate the cytokines in gingival crevicular fluid (GCF) of the teeth opposing dental implants and 3-unit fixed partial dentures (FPDs). Participants were divided into dental implants group and 3-unit FPDs group, and their occlusal loading and GCF cytokine levels were evaluated. The results showed that teeth opposing implants had higher levels of IL-10, IL-17, and RANK in GCF, which were associated with occlusion force. IL-10 might reflect a higher occlusion force in dental implants.