Related references
Note: Only part of the references are listed.An integrative genomics approach identifies KDM4 as a modulator of trained immunity
Simone J. C. F. M. Moorlag et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2022)
Neonatal BCG vaccination is associated with a long-term DNA methylation signature in circulating monocytes
Samantha Bannister et al.
SCIENCE ADVANCES (2022)
Aconitate decarboxylase 1 is a mediator of polymicrobial sepsis
Runliu Wu et al.
SCIENCE TRANSLATIONAL MEDICINE (2022)
Plasma metabolome predicts trained immunity responses after antituberculosis BCG vaccination
Valerie A. C. M. Koeken et al.
PLOS BIOLOGY (2022)
Dimethyl Itaconate Alleviates the Inflammatory Responses of Macrophages in Sepsis
Sheng Zhang et al.
INFLAMMATION (2021)
Inhibition of succinate dehydrogenase activity impairs human T cell activation and function
Claudia Nastasi et al.
SCIENTIFIC REPORTS (2021)
Staphylococcus aureus induces an itaconate-dominated immunometabolic response that drives biofilm formation
Kira L. Tomlinson et al.
NATURE COMMUNICATIONS (2021)
The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity
Giulio Cavalli et al.
CELL REPORTS (2021)
Glutathione Metabolism Contributes to the Induction of Trained Immunity
Anaisa V. Ferreira et al.
CELLS (2021)
Integrative metabolomics and transcriptomics identifies itaconate as an adjunct therapy to treat ocular bacterial infection
Sukhvinder Singh et al.
CELL REPORTS MEDICINE (2021)
Protocol In vitro induction of trained immunity in adherent human monocytes
Jorge Dominguez-Andres et al.
STAR PROTOCOLS (2021)
Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation
Sebastian A. Riquelme et al.
CELL METABOLISM (2020)
The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan
Samuel T. Keating et al.
CELL REPORTS (2020)
Changes in Plasma Itaconate Elevation in Early Rheumatoid Arthritis Patients Elucidates Disease Activity Associated Macrophage Activation
Ronan Daly et al.
METABOLITES (2020)
BCG vaccination in humans inhibits systemic inflammation in a sex-dependent manner
Valerie A. C. M. Koeken et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Itaconate controls the severity of pulmonary fibrosis
Patricia P. Ogger et al.
SCIENCE IMMUNOLOGY (2020)
Comparative evaluation of itaconate and its derivatives reveals divergent inflammasome and type I interferon regulation in macrophages
Amanda Swain et al.
NATURE METABOLISM (2020)
Identification of bioactive metabolites using activity metabolomics
Markus M. Rinschen et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Itaconate as an immune modulator
Anaisa V. Ferreira et al.
AGING-US (2019)
S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate
Wei Qin et al.
NATURE CHEMICAL BIOLOGY (2019)
4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects
Shan-Ting Liao et al.
NATURE COMMUNICATIONS (2019)
The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity
Jorge Dominguez-Andres et al.
CELL METABOLISM (2019)
mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human Monocytes
Yahya Sohrabi et al.
FRONTIERS IN IMMUNOLOGY (2019)
Chronic granulomatous disease 2018: advances in pathophysiology and clinical management
Reinhard A. Seger
LYMPHOSIGN JOURNAL-THE JOURNAL OF INHERITED IMMUNE DISORDERS (2019)
BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis
Eva Kaufmann et al.
CELL (2018)
BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity
Rob J. W. Arts et al.
CELL HOST & MICROBE (2018)
Blocking fatty acid-fueled mROS production within macrophages alleviates acute gouty inflammation
Christopher J. Hall et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Irg1 expression in myeloid cells prevents immunopathology during M-tuberculosis infection
Sharmila Nair et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
Electrophilic properties of itaconate and derivatives regulate the I kappa B zeta-ATF3 inflammatory axis
Monika Bambouskova et al.
NATURE (2018)
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
Evanna L. Mills et al.
NATURE (2018)
Role of glutathione in the regulation of epigenetic mechanisms in disease
Jose Luis Garcia-Gimenez et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
IRG1 increases MHC class I level in macrophages through STAT-TAP1 axis depending on NADPH oxidase mediated reactive oxygen species
Xing Liu et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2017)
Quantitative NMR analysis of intra-and extracellular metabolism of mammalian cells: A tutorial
Sarantos Kostidis et al.
ANALYTICA CHIMICA ACTA (2017)
β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance
Boris Novakovic et al.
CELL (2016)
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
Vicky Lampropoulou et al.
CELL METABOLISM (2016)
Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels
Thekla Cordes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Immunometabolic Pathways in BCG-Induced Trained Immunity
Rob J. W. Arts et al.
CELL REPORTS (2016)
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid
Jan Naujoks et al.
PLOS PATHOGENS (2016)
mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity
Shih-Chin Cheng et al.
SCIENCE (2014)
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
Sadia Saeed et al.
SCIENCE (2014)
Immunoresponsive Gene 1 Augments Bactericidal Activity of Macrophage-Lineage Cells by Regulating β-Oxidation-Dependent Mitochondrial ROS Production
Christopher J. Hall et al.
CELL METABOLISM (2013)
Immune Responsive Gene 1 (IRG1) Promotes Endotoxin Tolerance by Increasing A20 Expression in Macrophages through Reactive Oxygen Species
Yingke Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
Alessandro Michelucci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Matrix eQTL: ultra fast eQTL analysis via large matrix operations
Andrey A. Shabalin
BIOINFORMATICS (2012)
Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes
Jessica Quintin et al.
CELL HOST & MICROBE (2012)
Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes
Johanneke Kleinnijenhuis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
High-Throughput, Accurate Mass Metabolome Profiling of Cellular Extracts by Flow Injection - Time-of-Flight Mass Spectrometry
Tobias Fuhrer et al.
ANALYTICAL CHEMISTRY (2011)
Haplotype and isoform specific expression estimation using multi-mapping RNA-seq reads
Ernest Turro et al.
GENOME BIOLOGY (2011)
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
Sven Heinz et al.
MOLECULAR CELL (2010)
Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence
EJ Muñoz-Elías et al.
NATURE MEDICINE (2005)
Itaconate reduces visceral fat by inhibiting fructose 2,6-bisphosphate synthesis in rat liver
A Sakai et al.
NUTRITION (2004)
Share Paper
