Co-infection with Mycobacterium tuberculosis and Nocardia farcinica in a COPD patient: a case report

Review Medicine, General & Internal

Clinical Characteristics and Treatment Outcome of Central Nervous System Nocardiosis: A Systematic Review of Reported Cases

Durga Shankar Meena et al.

Summary: Systemic nocardiosis involving the central nervous system is a significant condition with high mortality, particularly in patients with impaired immune function. This systematic review examines the epidemiology, clinical features, diagnosis, therapeutic interventions, and outcomes of patients with central nervous system nocardiosis. The study suggests that a combination of surgery and antimicrobial therapy may improve clinical outcomes.

MEDICAL PRINCIPLES AND PRACTICE (2022)

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Review Infectious Diseases

How do I manage nocardiosis?

Ili Margalit et al.

Summary: Nocardiosis, a rare infection, primarily affects immunocompromised individuals, commonly involving the lungs and potentially spreading to other sites. Trimethoprim-sulfamethoxazole is the preferred initial therapy due to its high susceptibility against Nocardia, being a cornerstone of treatment for years.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

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Article Medicine, General & Internal

Pneumocystis jiroveci pneumonia, Nocardia brasiliensis, and Mycobacterium tuberculosis co-infection in a myasthenia gravis patient A case report

Jiahui Hou et al.

Summary: Myasthenia gravis (MG) is an autoimmune disorder that can lead to muscle weakness and fatigue. Patients with MG are more susceptible to respiratory infections due to weakened respiratory muscles. In this reported case, a MG patient on long-term steroid therapy developed a rare coinfection with Pneumocystis jirovecii, Nocardia brasiliensis, and Mycobacterium tuberculosis (MTB), highlighting the importance of recognizing the predisposition of MG patients to co-infections for better treatment outcomes.

MEDICINE (2021)

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Article Respiratory System

Effects of Empirical Glucocorticoid Use on Severe Acute Exacerbation of COPD During Hospitalization

Ling Wu et al.

Summary: This study aimed to investigate the impact of glucocorticoid use during hospitalization in COPD patients. The results showed that the annual rate of future COPD exacerbations was significantly lower in the glucocorticoid group compared to the control group. Subgroup analysis revealed that the use of glucocorticoids was particularly effective in patients with blood eosinophil <100 cells/μl.

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2021)

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Article Microbiology