☆ 4.6 Review

Gut Microbiota and its Metabolites: Bridge of Dietary Nutrients and Alzheimer's Disease

ADVANCES IN NUTRITION (2023)

Related references

Note: Only part of the references are listed.
Article Medicine, General & Internal

Lecanemab in Early Alzheimer's Disease

Christopher H. van Dyck et al.

Summary: Lecanemab, a humanized monoclonal antibody, reduced amyloid markers and showed improvement in cognition and function in early Alzheimer's disease patients. However, it also resulted in adverse events. Longer trials are needed to determine its efficacy and safety in early Alzheimer's disease.

NEW ENGLAND JOURNAL OF MEDICINE (2023)

Add to Collection
Article Biochemistry & Molecular Biology

Selenium supplementation enhanced the expression of selenoproteins in hippocampus and played a neuroprotective role in LPS-induced neuroinflammation

Xiaosheng Liang et al.

Summary: Selenium deficiency and decreased selenoprotein functions are linked to cognitive decline and neurodegenerative diseases. Dietary supplementation of sodium selenite can alleviate neuroinflammation and improve cognition in mouse models. The neuroprotective role of selenium may be attributed to the increased expression of selenoproteins, including SELENOP and GPX4.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

Add to Collection
Review Microbiology

Bile acids and the gut microbiota: metabolic interactions and impacts on disease

Stephanie L. Collins et al.

Summary: This Review discusses host-microbiota interactions and their impact on bile acid metabolism and composition. The gut microbiota plays a crucial role in bile acid metabolism, with diverse biological roles for bile acids being discovered. External factors such as antibiotics and diet also influence bile acid composition. Understanding the impact of bile acid signaling networks in different organs is increasingly important for the development of targeted therapeutics.

NATURE REVIEWS MICROBIOLOGY (2023)

Add to Collection
Article Microbiology

Predicting Neurodegenerative Disease Using Prepathology Gut Microbiota Composition: a Longitudinal Study in Mice Modeling Alzheimer's Disease Pathologies

Emily M. Borsom et al.

Summary: The gut microbiota-brain axis is believed to play a role in the development of Alzheimer's disease, and this study shows that the composition of the gut microbiota is associated with the development of AD pathologies. The study also demonstrates the potential of using microbiota features as a predictor of AD.

MICROBIOLOGY SPECTRUM (2023)

Add to Collection
Review Biochemistry & Molecular Biology

Magnesium and the Brain: A Focus on Neuroinflammation and Neurodegeneration

Jeanette A. M. Maier et al.

Summary: Magnesium plays a crucial role in regulating metabolism and maintaining tissue homeostasis, including the brain. It is essential for nerve signal transmission and protecting the blood-brain barrier. Deficiency in magnesium can lead to systemic low-grade inflammation, which is common in various diseases, particularly neurodegenerative disorders. This review provides evidence linking magnesium imbalance to multiple sclerosis, Alzheimer's, and Parkinson's diseases.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Add to Collection
Article Immunology

Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: A randomized clinical trial

Peijun Tian et al.

Summary: The study demonstrated that Bifidobacterium breve CCFM1025 has a promising antidepressant effect in managing major depression disorder. Compared to placebo, CCFM1025 showed better relief of depressive symptoms, possibly through changes in gut microbiome and tryptophan metabolism.

BRAIN BEHAVIOR AND IMMUNITY (2022)

Add to Collection
Review Cell Biology

Emerging targetome and signalome landscape of gut microbial metabolites

Xiao Zheng et al.

Summary: The interaction between microbial metabolites and host targets plays a crucial role in signal transmission and biological regulation. Understanding the interaction between microbial metabolites and host targets can provide new insights into host health and disease, expand the range of druggable targets, and inspire drug design and discovery.

CELL METABOLISM (2022)

Add to Collection
Article Nutrition & Dietetics

Integrative Metabolomic Characterization Reveals the Mediating Effect of Bifidobacterium breve on Amino Acid Metabolism in a Mouse Model of Alzheimer's Disease

Guangsu Zhu et al.

Summary: Alzheimer's disease is characterized by global metabolic alterations, leading to cognitive impairment. This study found that B. breve CCFM1025 intervention can restore the metabolic changes induced by Aβ injection, particularly in amino acid metabolism.

NUTRIENTS (2022)

Add to Collection
Article Clinical Neurology

Combination of gut microbiota and plasma amyloid-β as a potential index for identifying preclinical Alzheimer's disease: a cross-sectional analysis from the SILCODE study

Can Sheng et al.

Summary: This study found that the composition of gut microbiota is altered in preclinical AD, and the combination of plasma Aβ and gut microbiota can serve as a diagnostic tool for early AD screening.

ALZHEIMERS RESEARCH & THERAPY (2022)

Add to Collection
Article Microbiology

Stratification of the Gut Microbiota Composition Landscape across the Alzheimer's Disease Continuum in a Turkish Cohort

Süleyman Yıldırım et al.

mSystems (2022)

Add to Collection
Review Cell Biology

The role of serotonin within the microbiota-gut-brain axis in the development of Alzheimer's disease: A narrative review

Emma Aaldijk et al.

Summary: This review summarizes the available evidence concerning the orchestrating role of serotonin within the microbiota-gut-brain axis in the development of Alzheimer's disease (AD), and highlights general considerations for future studies.

AGEING RESEARCH REVIEWS (2022)

Add to Collection
Article Nutrition & Dietetics

Vitamin D and brain health: an observational and Mendelian randomization study

Shreeya S. Navale et al.

Summary: This study found an association between low vitamin D status and neuroimaging outcomes, as well as the risks of dementia and stroke. Vitamin D deficiency may increase the risk of dementia, but has no effect on stroke risk.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)

Add to Collection
Review Nutrition & Dietetics

Dietary and supplemental long-chain omega-3 fatty acids as moderators of cognitive impairment and Alzheimer's disease

Amy H. R. Wood et al.

Summary: This review summarizes evidence from observational studies and clinical trials on the protective effect of LC omega-3 PUFAs against cognitive impairment and reduced risk of Alzheimer's disease. Findings suggest that individuals consuming higher amounts of LC omega-3 PUFAs are less likely to develop cognitive impairment and may benefit from a preventative strategy against Alzheimer's disease when consumed prior to or in the early stages of cognitive decline.

EUROPEAN JOURNAL OF NUTRITION (2022)

Add to Collection
Review Behavioral Sciences

Can dietary patterns prevent cognitive impairment and reduce Alzheimer's disease risk: Exploring the underlying mechanisms of effects

Chuan-Qi Chu et al.

Summary: Dietary patterns have significant effects on cognitive function and the development of Alzheimer's disease (AD), although the underlying mechanisms are not fully understood. This article provides a comprehensive overview of the effects of different dietary patterns on cognitive impairment, highlighting the modulation of cognitive impairment through gut microbiota. A framework for developing personalized dietary patterns based on individual gut microbiome compositions is proposed.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2022)

Add to Collection
Article Cell Biology

Vitamin D supplementation worsens Alzheimer's progression: Animal model and human cohort studies

Rai-Hua Lai et al.

Summary: Vitamin D deficiency may not be the cause but a consequence of AD. Supplementation of vitamin D in AD mice and humans exacerbates AD and enhances the non-genomic VDR/p53 complex in the brain. Long-term use of vitamin D-3 supplements may increase the risk of dementia and mortality.

AGING CELL (2022)

Add to Collection
Review Nutrition & Dietetics

Diet in the Prevention of Alzheimer's Disease: Current Knowledge and Future Research Requirements

Oliwia Stefaniak et al.

Summary: Alzheimer's disease is a progressive brain disease that is becoming a major health issue due to the aging population. Nutrition plays a crucial role in preventing and delaying the development of the disease, with diets rich in neuroprotective nutrients such as antioxidants, B vitamins, and polyunsaturated fatty acids recommended. Studies have shown that healthy dietary patterns like the Mediterranean diet can reduce the risk of Alzheimer's disease.

NUTRIENTS (2022)

Add to Collection
Article Endocrinology & Metabolism

Metabolic Messengers: bile acids

Alessia Perino et al.

Summary: Bile acids are amphipathic steroid acids that play a crucial role in the regulation of metabolic responses. Their actions through activation of specific receptors control energy homeostasis and alterations in bile acid signaling are associated with metabolic diseases. Modulation of the bile acid pool could be a potential therapeutic approach.

NATURE METABOLISM (2022)

Add to Collection
Article Nutrition & Dietetics

Long-term dietary protein intake and subjective cognitive decline in US men and women

Tian-Shin Yeh et al.

Summary: This study revealed that higher protein intake, especially when compared to carbohydrates, was associated with lower odds of subjective cognitive decline. Plant protein sources were also found to be beneficial in reducing the risk of cognitive decline compared to animal protein sources.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)

Add to Collection
Article Neurosciences

Adherence to a Mediterranean diet is associated with cognitive function in an older non-Mediterranean sample: findings from the Maine-Syracuse Longitudinal Study

Alexandra T. Wade et al.

Summary: This study found an association between adherence to a Mediterranean diet and cognitive function in middle-aged and older individuals. Particularly, higher adherence to a Mediterranean diet was associated with improvements in cognitive function in participants aged 70 and above.

NUTRITIONAL NEUROSCIENCE (2021)

Add to Collection
Review Nutrition & Dietetics

Probiotics for dementia: a systematic review and meta-analysis of randomized controlled trials

Jenifer F. Kruger et al.

Summary: Probiotic supplementation did not show significant benefits on cognitive function in individuals with dementia, but did improve certain metabolic markers. The current evidence is insufficient to support the clinical application of probiotics and synbiotics for individuals with dementia.

NUTRITION REVIEWS (2021)

Add to Collection
Article Neurosciences

Gut microbiota interacts with intrinsic brain activity of patients with amnestic mild cognitive impairment

Ping Liu et al.

Summary: The study revealed that alterations in gut microbiota (GM) in patients with amnestic mild cognitive impairment (aMCI) can impact local spontaneous brain activity and subsequently affect cognitive function. Specific correlations were found between different GM compositions and brain activity. Members of Clostridium were positively correlated with brain activity, while Veillonellaceae showed a negative correlation.

CNS NEUROSCIENCE & THERAPEUTICS (2021)

Add to Collection
Review Urology & Nephrology

Food as medicine: targeting the uraemic phenotype in chronic kidney disease

Denise Mafra et al.

Summary: The authors discuss how food and specific nutrients could affect the uraemic phenotype in chronic kidney disease (CKD). They suggest using a food-as-medicine approach to prevent and treat CKD. Unhealthy diets have been identified as a major risk factor for poor health outcomes, sparking interest in the concept of 'food as medicine', especially in metabolic diseases like CKD.

NATURE REVIEWS NEPHROLOGY (2021)

Add to Collection
Review Neurosciences

Bile Acids: A Communication Channel in the Gut-Brain Axis

Vera F. Monteiro-Cardoso et al.

Summary: Bile acids are signalling hormones involved in the regulation of metabolic pathways, modulated by the gut microbiome. Gut bacteria send signals to the central nervous system, impacting brain function. Despite increasing understanding of the role of bile acids in the central nervous system, little is known about their molecular mechanisms and physiological roles.

NEUROMOLECULAR MEDICINE (2021)

Add to Collection
Article Geriatrics & Gerontology

Strength training or green tea prevent memory deficits in a β-amyloid peptide-mediated Alzheimer's disease model

Helen L. Schimidt et al.

Summary: Strength exercise can improve memory impairments, green tea supplementation can enhance antioxidant capacity, and the combination of strength exercise and green tea has a certain effect on improving memory impairments.

EXPERIMENTAL GERONTOLOGY (2021)

Add to Collection
Review Clinical Neurology

Vitamin D in the development and progression of alzheimer's disease: implications for clinical management

Francesco Panza et al.

Summary: Insufficient and deficient levels of vitamin D may increase susceptibility to Alzheimer's disease. Further research and clinical trials are needed to fully understand the relationship between vitamin D levels and AD, as well as the effectiveness of vitamin D supplementation for prevention or treatment.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2021)

Add to Collection
Review Clinical Neurology

Effects of probiotics supplementation on dementia and cognitive impairment: A systematic review and meta-analysis of preclinical and clinical studies

Cristofer Ruiz-Gonzalez et al.

Summary: The study found that probiotics have a positive impact on MCI and dementia, improving cognitive function, memory, and learning abilities, as well as regulating brain-derived neurotrophic factor levels and improving inflammatory profiles.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2021)

Add to Collection
Article Clinical Neurology

Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer's disease

Luke Whiley et al.

Summary: The study found significantly lower concentrations of tryptophan pathway metabolites in the AD group, while higher concentrations of indoleamine pathway metabolites were observed. Concentrations of various metabolites showed a decreasing trend with clinical diagnosis: control > MCI > AD. There were no significant differences between the two MCI subgroups, and the use of SSRI medication influenced serum observations but not urine results.

ALZHEIMERS RESEARCH & THERAPY (2021)

Add to Collection
Article Gastroenterology & Hepatology

Leveraging diet to engineer the gut microbiome

Mathis Wolter et al.

Summary: Autoimmune diseases share patterns of gut microbiome perturbation and immune dysregulation linked to intestinal barrier dysfunction. Dietary tools for precise engineering of the gut microbiome have the potential to modulate host-microbiome interaction in the treatment of autoimmune diseases.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

Add to Collection
Article Neurosciences

Gut Microbiome Features of Chinese Patients Newly Diagnosed with Alzheimer's Disease or Mild Cognitive Impairment

Mingyan Guo et al.

Summary: This study revealed that patients newly diagnosed with AD or MCI have gut dysbiosis, characterized by a decrease in potentially protective microbiome and an increase in microbiome promoting inflammation. Furthermore, the degree of gut dysbiosis worsens as the disease progresses from MCI to AD.

JOURNAL OF ALZHEIMERS DISEASE (2021)

Add to Collection
Review Medicine, General & Internal

Alzheimer's disease

Philip Scheltens et al.

Summary: Alzheimer's disease is projected to see a significant increase in prevalence in the future, with genetics playing a key role. Novel biomarkers and lifestyle-based prevention trials show promising therapeutic potential. Promising pharmacological treatments are advancing in clinical trials, targeting amyloid beta, tau, and inflammation.

LANCET (2021)

Add to Collection
Article Biochemistry & Molecular Biology

The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk

Dong D. Wang et al.

Summary: The study shows that a healthy Mediterranean-style diet is linked to specific functional and taxonomic components of the gut microbiome, and its protective effects on cardiometabolic health depend on microbial composition. In particular, the protective association between adherence to the Mediterranean diet and cardiometabolic disease risk is significantly stronger among participants with decreased abundance of Prevotella copri.

NATURE MEDICINE (2021)

Add to Collection
Review Gastroenterology & Hepatology

Disorders of the enteric nervous system - a holistic view

Beate Niesler et al.

Summary: The enteric nervous system (ENS) plays a crucial role in congenital enteric neuropathic disorders, but its role in systemic diseases is less understood. Evidence suggests that the ENS is emerging as a key player in neurodegenerative diseases, cancer, and diabetes, regulating gut function and contributing to various disorders by interacting with the gut microbiome, genetic background, central nervous system, and immune system.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

Add to Collection
Article Food Science & Technology

Postbiotics: Metabolites and mechanisms involved in microbiota-host interactions

Maria do Carmo Gouveia Peluzio et al.

Summary: Postbiotics, produced through the fermentation of dietary components, play a crucial role in influencing human health. Short-chain fatty acids serve as a primary energy source for colonocytes, polyamines promote homeostasis, and bile acids are involved in regulating glucose metabolism and the host immune response.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2021)

Add to Collection
Article Neurosciences

APOE-ε4 Carrier Status and Gut Microbiota Dysbiosis in Patients With Alzheimer Disease

Min Hou et al.

Summary: This study analyzed the gut microbiota composition and risk genetic variants in Alzheimer's disease (AD) patients and healthy controls, revealing a correlation between the APOE ε4 allele and AD development, as well as a positive association with certain pathogens. Targeting the microbiota might be an effective therapeutic strategy for AD patients susceptible to the APOE ε4 allele, but further investigation is needed.

FRONTIERS IN NEUROSCIENCE (2021)

Add to Collection
Review Chemistry, Multidisciplinary

Polyphenol-Containing Nanoparticles: Synthesis, Properties, and Therapeutic Delivery

Yuxin Guo et al.

Summary: Polyphenols, commonly found in plants, have beneficial effects on human health and their use in nanoparticles shows promising potential for various biomedical applications. Their coordination with metal ions forms important complexes with applications in surface modification, bioimaging, drug delivery, and disease treatments. The versatility of polyphenol-containing nanoparticles in different biomedical applications has been demonstrated, with challenges for future research being discussed.

ADVANCED MATERIALS (2021)

Add to Collection
Review Cell Biology

Alzheimer's disease as a chronic maladaptive polyamine stress response

Baruh Polis et al.

Summary: Polyamines are nitrogen-rich polycationic molecules with diverse evolutionary-conserved functions, playing pleiotropic, adaptive, and pathogenic roles in age-related neurodegenerative diseases. A universal short-term polyamine stress response is beneficial for survival but becomes detrimental following chronic stimuli, particularly in aging organisms. Fine-tuning arginase activity with natural inhibitors may be a novel treatment strategy for AD-related dementia.

AGING-US (2021)

Add to Collection
Article Nutrition & Dietetics

Meat consumption and risk of incident dementia: cohort study of 493,888 UK Biobank participants

Huifeng Zhang et al.

Summary: The study found that processed meat consumption may be associated with an increased risk of incident dementia, while increased intake of unprocessed red meat may be related to a reduced risk of dementia. The APOE ε4 allele increases the risk of dementia by 3 to 6 times.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2021)

Add to Collection
Article Immunology

Mannan oligosaccharide attenuates cognitive and behavioral disorders in the 5xFAD Alzheimer's disease mouse model via regulating the gut microbiota-brain axis

Qing Liu et al.

Summary: The study demonstrated that prebiotic mannan oligosaccharide (MOS) significantly improved cognitive function and mental symptoms, reduced anxiety and obsessive behaviors, and enhanced neuroprotection in the 5xFAD transgenic AD mice model. MOS treatment also balanced brain oxidative status, suppressed neuroinflammatory responses, alleviated HPA-axis disorders, and prevented gut barrier damage.

BRAIN BEHAVIOR AND IMMUNITY (2021)

Add to Collection
Article Neurosciences

Gut Microbiota Changes and Their Correlation with Cognitive and Neuropsychiatric Symptoms in Alzheimer's Disease

Yunzhe Zhou et al.

Summary: This study found significant differences in the gut microbiota composition between AD patients and healthy controls, with different taxa showing varied correlations with cognitive function and NPS. These findings contribute to a better understanding of the pathogenesis of AD and the potential therapeutic targets.

JOURNAL OF ALZHEIMERS DISEASE (2021)

Add to Collection
Article Chemistry, Medicinal

Epigallocatechin-3-Gallate Provides Protection Against Alzheimer's Disease-Induced Learning and Memory Impairments in Rats

Shanji Nan et al.

Summary: Recent evidence suggests that EGCG, a constituent of Green Tea Polyphenols, may have anti-inflammatory properties and exert a neuroprotective effect on Alzheimer's disease. In AD rat models, EGCG intervention decreased escape latency period, decreased Tau hyperphosphorylation, suppressed BACE1 expression and A beta 1-42 expression, and promoted Ach content by diminishing AchE activity. These findings suggest that EGCG may improve the antioxidant system and learning and memory function in rats with AD.

DRUG DESIGN DEVELOPMENT AND THERAPY (2021)

Add to Collection
Article Nutrition & Dietetics

Administration of Bifidobacterium breve Improves the Brain Function of Aβ1-42-Treated Mice via the Modulation of the Gut Microbiome

Guangsu Zhu et al.

Summary: This study found that the administration of bifidobacteria improved behavioral abnormalities and synaptic plasticity in an AD mouse model. The microbiome and metabolomic profiles of the mice indicated a correlation between specific bacterial taxa and their metabolites with AD-associated behaviors, suggesting the involvement of the gut-brain axis in the pathophysiology of AD. Overall, B. breve CCFM1025 and WX represent a novel probiotic dietary intervention for delaying the progression of AD by modulating the gut microbiome.

NUTRIENTS (2021)

Add to Collection
Article Immunology

Exploring the microbiota-Alzheimer's disease linkage using short-term antibiotic treatment followed by fecal microbiota transplantation

Min Wang et al.

Summary: The study established a novel AD mouse model with a near-germ-free status using antibiotic treatment and fecal microbiota transplantation, demonstrating an increase in Aβ plaques and suppression of astrocyte activation surrounding the plaques following microbiota engraftment.

BRAIN BEHAVIOR AND IMMUNITY (2021)

Add to Collection
Review Food Science & Technology

Dietary prospects of coconut oil for the prevention and treatment of Alzheimer's disease (AD): A review of recent evidences

S. V. Ramesh et al.

Summary: Coconut oil and its derivatives show promising potential as therapeutic agents for Alzheimer's disease, with their ability to regulate brain glucose metabolism and improve cognitive decline. However, further research is needed to identify bioactive components beyond MCFAs, conduct clinical trials to determine optimal dosages, and streamline information dissemination in the treatment of AD.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2021)

Add to Collection
Article Microbiology

Human gut-derived B. longum subsp. longum strains protect against aging in a D-galactose-induced aging mouse model

Yue Xiao et al.

Summary: This study identified geographically distinct gene pools/populations among Bifidobacterium longum strains and explored the mechanisms of probiotics on promoting host longevity. The research revealed different abilities of strains with different genotypes in combating host aging and provided new insights into the use of specific probiotics or molecules for promoting host longevity.

MICROBIOME (2021)

Add to Collection
Review Food Science & Technology

Probiotics for Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review and Meta-Analysis

Guangsu Zhu et al.

Summary: Analysis of randomized controlled trials suggests that dietary supplementation with probiotics may improve cognitive function, particularly in individuals with mild cognitive impairment.

FOODS (2021)

Add to Collection
Article Cell Biology

Microbiota from young mice counteracts selective age-associated behavioral deficits

Marcus Boehme et al.

Summary: The study demonstrates that rejuvenation of the gut microbiome by fecal microbiota transplantation from young mice can reverse aging-induced differences in the immune system, metabolome, and transcriptome, and improve specific cognitive deficits.

NATURE AGING (2021)

Add to Collection
Article Nutrition & Dietetics

Improved metabolic function and cognitive performance in middle-aged adults following a single dose of wild blueberry

Adrian R. Whyte et al.

Summary: Research has shown that consuming wild blueberries can improve memory and executive function in middle-aged adults, reducing cognitive fatigue. Additionally, wild blueberries also improve post-meal glucose and insulin responses. Further investigation is needed to understand the underlying mechanisms of how wild blueberries enhance cognitive function.

EUROPEAN JOURNAL OF NUTRITION (2021)

Add to Collection
Article Geriatrics & Gerontology

Mediterranean diet adherence is associated with better cognitive status and less depressive symptoms in a Greek elderly population

Maria Mantzorou et al.

Summary: This study evaluated the adherence of an elderly Greek population to the Mediterranean diet and its association with cognitive decline and psychological status. The results showed that higher adherence to the Mediterranean diet was linked to better cognitive and psychological status, as well as younger age, female gender, higher education level, and better anthropometric parameters. Public health policies are advised to focus on promoting the Mediterranean diet to reduce the risk of cognitive impairment and depression.

AGING CLINICAL AND EXPERIMENTAL RESEARCH (2021)

Add to Collection
Article Neurosciences

Synbiotic supplementation, systemic inflammation, and symptoms of brain disorders in elders: A secondary study from a randomized clinical trial

Eliana Regina Louzada et al.

NUTRITIONAL NEUROSCIENCE (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Polyphenolic Biflavonoids Inhibit Amyloid-Beta Fibrillation and Disaggregate Preformed Amyloid-Beta Fibrils

Erika Y. Choi et al.

BIOMOLECULES & THERAPEUTICS (2020)

Add to Collection
Review Clinical Neurology

The gut microbiome in neurological disorders

John F. Cryan et al.

LANCET NEUROLOGY (2020)

Add to Collection
Review Cell Biology

Efficacy of probiotics on cognition, and biomarkers of inflammation and oxidative stress in adults with Alzheimer's disease or mild cognitive impairment - a meta-analysis of randomized controned trials

Haoyue Deng et al.

AGING-US (2020)

Add to Collection
Article Gastroenterology & Hepatology

Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake

Victoria Meslier et al.

GUT (2020)

Add to Collection
Review Biochemistry & Molecular Biology

The therapeutic and nutraceutical potential of agmatine, and its enhanced production using Aspergillus oryzae

Naoki Akasaka et al.

AMINO ACIDS (2020)

Add to Collection
Review Cell Biology

Interaction between microbiota and immunity in health and disease

Danping Zheng et al.

CELL RESEARCH (2020)

Add to Collection
Editorial Material Nutrition & Dietetics

High Intake of Sugar and the Balance between Pro- and Anti-Inflammatory Gut Bacteria

Reetta Satokari

NUTRIENTS (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Toward Understanding Microbiome-Neuronal Signaling

K. G. Jameson et al.

MOLECULAR CELL (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Omega-3 Fatty Acid-Type Docosahexaenoic Acid Protects against Aβ-Mediated Mitochondrial Deficits and Pathomechanisms in Alzheimer's Disease-Related Animal Model

Yong Ho Park et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection
Article Gastroenterology & Hepatology

Human resident gut microbeBacteroides thetaiotaomicronregulates colonic neuronal innervation and neurogenic function

Rubina Aktar et al.

GUT MICROBES (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Vitamin A and Retinoic Acid in Cognition and Cognitive Disease

Marta U. Woloszynowska-Fraser et al.

ANNUAL REVIEW OF NUTRITION, VOL 40, 2020 (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Inhibition of Aβ aggregates in Alzheimer's disease by epigallocatechin and epicatechin-3-gallate from green tea

Tingting Chen et al.

BIOORGANIC CHEMISTRY (2020)

Add to Collection
Article Multidisciplinary Sciences

Microbiota modulate sympathetic neurons via a gut-brain circuit

Paul A. Muller et al.

NATURE (2020)

Add to Collection
Article Geriatrics & Gerontology

Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer’s disease mouse model

Elisabete Ferreiro et al.

NEUROBIOLOGY OF AGING (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Mulberry Fruit Extract Alleviates Cognitive Impairment by Promoting the Clearance of Amyloid-β and Inhibiting Neuroinflammation in Alzheimer's Disease Mice

Dianxun Liu et al.

NEUROCHEMICAL RESEARCH (2020)

Add to Collection
Article Food Science & Technology

Modulation of neuroinflammatory pathways by medicinal mushrooms, with particular relevance to Alzheimer's disease

Naufal Kushairi et al.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Yeast β-glucan alleviates cognitive deficit by regulating gut microbiota and metabolites in Aβ1-42-induced AD-like mice

Mengdai Xu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Bile Acid Signaling in Neurodegenerative and Neurological Disorders

Stephanie M. Grant et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Neuroprotective Effects of Chronic Resveratrol Treatment and Exercise Training in the 3xTg-AD Mouse Model of Alzheimer's Disease

Tom L. Broderick et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection
Article Gastroenterology & Hepatology

The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics

Kelly S. Swanson et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)

Add to Collection
Review Neurosciences

Gut microbial molecules in behavioural and neurodegenerative conditions

Brittany D. Needham et al.

NATURE REVIEWS NEUROSCIENCE (2020)

Add to Collection
Article Multidisciplinary Sciences

Vitamin D metabolites and the gut microbiome in older men

Robert L. Thomas et al.

NATURE COMMUNICATIONS (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Effect of oral administration of Magnesium N-Acetyltaurinate on synaptic plasticity in rodents

Manon Fassin et al.

MAGNESIUM RESEARCH (2020)

Add to Collection
Correction Biochemistry & Molecular Biology

Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome (vol 182, pg 1460, 2020)

Ruben A. T. Mars et al.

CELL (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Up-regulation of neprilysin mediates the protection of fructo-oligosaccharides against Alzheimer's disease

Sining Wu et al.

FOOD & FUNCTION (2020)

Add to Collection
Review Oncology

Dietary patterns and cancer risk

Susan E. Steck et al.

NATURE REVIEWS CANCER (2020)

Add to Collection
Article Geriatrics & Gerontology

Prebiotics Regulation of Intestinal Microbiota Attenuates Cognitive Dysfunction Induced by Surgery Stimulation in APP/PS1 Mice

Dengyang Han et al.

AGING AND DISEASE (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Dietary Protein and Gut Microbiota Composition and Function

Jianfei Zhao et al.

CURRENT PROTEIN & PEPTIDE SCIENCE (2019)

Add to Collection
Article Oncology

Long non-coding RNA HOXA-AS2 promotes the migration, invasion and stemness of bladder cancer via regulating miR-125b/Smad2 axis

Fei Wang et al.

EXPERIMENTAL CELL RESEARCH (2019)

Add to Collection
Article Agriculture, Multidisciplinary

Fructooligosaccharides Ameliorating Cognitive Deficits and Neurodegeneration in APP/PS1 Transgenic Mice through Modulating Gut Microbiota

Jing Sun et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease

Elena P. Moreno-Jimenez et al.

NATURE MEDICINE (2019)

Add to Collection
Article Neurosciences

Tau immunoreactivity in peripheral tissues of human aging and select tauopathies

Brittany N. Dugger et al.

NEUROSCIENCE LETTERS (2019)

Add to Collection
Article Nutrition & Dietetics

Efficacy and Safety of Lactobacillus Plantarum C29-Fermented Soybean (DW2009) in Individuals with Mild Cognitive Impairment: A 12-Week, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Yun-Ha Hwang et al.

NUTRIENTS (2019)

Add to Collection
Article Multidisciplinary Sciences

Analysis of the relationship between the gut microbiome and dementia: a cross-sectional study conducted in Japan

Naoki Saji et al.

SCIENTIFIC REPORTS (2019)

Add to Collection
Article Clinical Neurology

A ketogenic drink improves brain energy and some measures of cognition in mild cognitive impairment

Melanie Fortier et al.

ALZHEIMERS & DEMENTIA (2019)

Add to Collection
Article Immunology

Altered microbiomes distinguish Alzheimer's disease from amnestic mild cognitive impairment and health in a Chinese cohort

Ping Liu et al.

BRAIN BEHAVIOR AND IMMUNITY (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Concentrations of bile acid precursors in cerebrospinal fluid of Alzheimer's disease patients

William J. Griffiths et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Add to Collection
Review Agriculture, Multidisciplinary

Review on Bile Acids: Effects of the Gut Microbiome, Interactions with Dietary Fiber, and Alterations in the Bioaccessibility of Bioactive Compounds

Jashbir Singh et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2019)

Add to Collection
Article Immunology

Sex-specific effects of microbiome perturbations on cerebral Aβ amyloidosis and microglia phenotypes

Hemraj B. Dodiya et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2019)

Add to Collection
Review Gastroenterology & Hepatology

The role of short-chain fatty acids in microbiota-gut-brain communication

Boushra Dalile et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)

Add to Collection
Article Microbiology

Alzheimer's Disease Microbiome Is Associated with Dysregulation of the Anti-Inflammatory P-Glycoprotein Pathway

John P. Haran et al.

MBIO (2019)

Add to Collection
Article Microbiology

Effects of Bifidobacterium breve A1 on the cognitive function of older adults with memory complaints: a randomised, double-blind, placebo-controlled trial

Y. Kobayashi et al.

BENEFICIAL MICROBES (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

Gil Sharon et al.

CELL (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Altered SPMs and age-associated decrease in brain DHA in APOE4 female mice

Anneloes Martinsen et al.

FASEB JOURNAL (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Inonotus obliquus polysaccharides protect against Alzheimer's disease by regulating Nrf2 signaling and exerting antioxidative and antiapoptotic effects

Yanqiu Han et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Add to Collection
Article Multidisciplinary Sciences

A novel synbiotic delays Alzheimer's disease onset via combinatorial gut-brain-axis signaling in Drosophila melanogaster

Susan Westfall et al.

PLOS ONE (2019)

Add to Collection
Article Nutrition & Dietetics

A Mediterranean Diet with Fresh, Lean Pork Improves Processing Speed and Mood: Cognitive Findings from the MedPork Randomised Controlled Trial

Alexandra T. Wade et al.

NUTRIENTS (2019)

Add to Collection
Article Clinical Neurology

Mild cognitive impairment has similar alterations as Alzheimer's disease in gut microbiota

Binyin Li et al.

ALZHEIMERS & DEMENTIA (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy

Rosina Pryor et al.

CELL (2019)

Add to Collection
Review Physiology

THE MICROBIOTA-GUT-BRAIN AXIS

John F. Cryan et al.

PHYSIOLOGICAL REVIEWS (2019)

Add to Collection
Article Multidisciplinary Sciences

Dietary inulin alters the gut microbiome, enhances systemic metabolism and reduces neuroinflammation in an APOE4 mouse model

Jared D. Hoffman et al.

PLOS ONE (2019)

Add to Collection
Review Nutrition & Dietetics

The Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diets Are Associated with Less Cognitive Decline and a Lower Risk of Alzheimer's Disease-A Review

Annelien C. van den Brink et al.

ADVANCES IN NUTRITION (2019)

Add to Collection
Review Psychiatry

Inflammation-related biomarkers in major psychiatric disorders: a cross-disorder assessment of reproducibility and specificity in 43 meta-analyses

Ning Yuan et al.

TRANSLATIONAL PSYCHIATRY (2019)

Add to Collection
Article Medicine, General & Internal

Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimer's disease markers in subjects with mild cognitive impairment

Ravinder Nagpal et al.

EBIOMEDICINE (2019)

Add to Collection
Article Medical Laboratory Technology

Effects of One Year of Vitamin D and Marine Omega-3 Fatty Acid Supplementation on Biomarkers of Systemic Inflammation in Older US Adults

Karen H. Costenbader et al.

CLINICAL CHEMISTRY (2019)

Add to Collection
Article Clinical Neurology

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers

Kwangsik Nho et al.

ALZHEIMERS & DEMENTIA (2019)

Add to Collection
Article Clinical Neurology

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome

Siamak MahmoudianDehkordi et al.

ALZHEIMERS & DEMENTIA (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Protective roles of Amanita caesarea polysaccharides against Alzheimer's disease via Nrf2 pathway

Zhiping Li et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Add to Collection
Article Clinical Neurology

Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial

James A. Blumenthal et al.

NEUROLOGY (2019)

Add to Collection
Article Neurosciences

Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder

Martina Sgritta et al.

NEURON (2019)

Add to Collection
Article Neurosciences

Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer's disease

Miho Ota et al.

NEUROSCIENCE LETTERS (2019)

Add to Collection
Article Plant Sciences

Neuroprotective effects of a Rhodiola crenulata extract on amyloid-β peptides (Aβ1-42) -induced cognitive deficits in rat models of Alzheimer's disease

Zhang Xiaoxue et al.

PHYTOMEDICINE (2019)

Add to Collection
Review Nutrition & Dietetics

Role of Dietary Lipids in Modulating Inflammation through the Gut Microbiota

Paul J. Wisniewski et al.

NUTRIENTS (2019)

Add to Collection
Article Microbiology

GABA-modulating bacteria of the human gut microbiota

Philip Strandwitz et al.

NATURE MICROBIOLOGY (2019)

Add to Collection
Review Clinical Neurology

MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study

Diane E. Hosking et al.

ALZHEIMERS & DEMENTIA (2019)

Add to Collection
Article Gastroenterology & Hepatology

A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota

Henry Watson et al.

GUT (2018)

Add to Collection
Article Neurosciences

Neurotransmitter modulation by the gut microbiota

Philip Strandwitz

BRAIN RESEARCH (2018)

Add to Collection
Article Biochemistry & Molecular Biology

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet

Christine A. Olson et al.

CELL (2018)

Add to Collection
Review Microbiology

Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease

Allison Agus et al.

CELL HOST & MICROBE (2018)

Add to Collection
Article Neurosciences

Gut Microbiota is Altered in Patients with Alzheimer's Disease

Zhen-Qian Zhuang et al.

JOURNAL OF ALZHEIMERS DISEASE (2018)

Add to Collection
Article Nutrition & Dietetics

Blueberry Supplementation Influences the Gut Microbiota, Inflammation, and Insulin Resistance in High-Fat-Diet-Fed Rats

Sunhye Lee et al.

JOURNAL OF NUTRITION (2018)

Add to Collection
Article Genetics & Heredity

The fecal metabolome as a functional readout of the gut microbiome

Jonas Zierer et al.

NATURE GENETICS (2018)

Add to Collection
Review Pharmacology & Pharmacy

Alzheimer's disease and gut microbiota modifications: The long way between preclinical studies and clinical evidence

Cesare Mancuso et al.

PHARMACOLOGICAL RESEARCH (2018)

Add to Collection
Review Physiology

ARGINASE: A MULTIFACETED ENZYME IMPORTANT IN HEALTH AND DISEASE

R. William Caldwell et al.

PHYSIOLOGICAL REVIEWS (2018)

Add to Collection
Article Public, Environmental & Occupational Health

Consuming sustainable seafood: guidelines, recommendations and realities

Anna K. Farmery et al.

PUBLIC HEALTH NUTRITION (2018)

Add to Collection
Review Food Science & Technology

Dietary polyphenols: A novel strategy to modulate microbiota-gut-brain axis

Diana Serra et al.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2018)

Add to Collection
Article Food Science & Technology

EPA enriched ethanolamine plasmalogens significantly improve cognition of Alzheimer's disease mouse model by suppressing β-amyloid generation

Hongxia Che et al.

JOURNAL OF FUNCTIONAL FOODS (2018)

Add to Collection
Article Multidisciplinary Sciences

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

Rachel Fellows et al.

NATURE COMMUNICATIONS (2018)

Add to Collection
Review Nutrition & Dietetics

Microbiome-Mediated Effects of the Mediterranean Diet on Inflammation

Melisa A. Bailey et al.

ADVANCES IN NUTRITION (2018)

Add to Collection
Article Microbiology

Shifts on Gut Microbiota Associated to Mediterranean Diet Adherence and Specific Dietary Intakes on General Adult Population

Izaskun Garcia-Mantrana et al.

FRONTIERS IN MICROBIOLOGY (2018)

Add to Collection
Article Clinical Neurology

Effects of Oligosaccharides From Morinda officinalis on Gut Microbiota and Metabolome of APP/PS1 Transgenic Mice

Yang Xin et al.

FRONTIERS IN NEUROLOGY (2018)

Add to Collection
Article Biochemistry & Molecular Biology

Phlorizin administration ameliorates cognitive deficits by reducing oxidative stress, tau hyper-phosphorylation, and neuroinflammation in a rat model of Alzheimer's disease

Yuan Tian et al.

JOURNAL OF FOOD BIOCHEMISTRY (2018)

Add to Collection
Article Immunology

Butyrate and Dietary Soluble Fiber Improve Neuroinflammation Associated With Aging in Mice

Stephanie M. Matt et al.

FRONTIERS IN IMMUNOLOGY (2018)

Add to Collection
Article Clinical Neurology

L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease

Baruh Polis et al.

NEUROTHERAPEUTICS (2018)

Add to Collection
Review Nutrition & Dietetics

The Role of Diet, Micronutrients and the Gut Microbiota in Age-Related Macular Degeneration: New Perspectives from the Gut-Retina Axis

Emanuele Rinninella et al.

NUTRIENTS (2018)

Add to Collection
Article Biochemistry & Molecular Biology

Resveratrol alleviates motor and cognitive deficits and neuropathology in the A53T-synuclein mouse model of Parkinson's disease

Li-fan Zhang et al.

FOOD & FUNCTION (2018)

Add to Collection
Review Multidisciplinary Sciences

Recent developments in understanding the role of the gut microbiota in brain health and disease

Eoin Sherwin et al.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2018)

Add to Collection
Article Food Science & Technology

Absorption and Metabolism of Phenolics from Digests of Polyphenol-Rich Potato Extracts Using the Caco-2/HepG2 Co-Culture System

Shima Sadeghi Ekbatan et al.

FOODS (2018)

Add to Collection
Article Neurosciences

Cognitive-Enhancing Effects of a Polyphenols-Rich Extract from Fruits without Changes in Neuropathology in an Animal Model of Alzheimer's Disease

Alexandre Dal-Pan et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Add to Collection
Review Chemistry, Medicinal

t Edible and Medicinal Mushrooms: Emerging Brain Food for the Mitigation of Neurodegenerative Diseases

Chia-Wei Phan et al.

JOURNAL OF MEDICINAL FOOD (2017)

Add to Collection
Article Geriatrics & Gerontology

Neuroprotective Diets Are Associated with Better Cognitive Function: The Health and Retirement Study

Claire T. McEvoy et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2017)

Add to Collection
Article Geriatrics & Gerontology

The Dietary Approaches to Stop Hypertension Diet, Cognitive Function, and Cognitive Decline in American Older Women

Agnes A. M. Berendsen et al.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2017)

Add to Collection
Article Clinical Neurology

Effect of long-term omega 3 polyunsaturated fatty acid supplementation with or without multidomain intervention on cognitive function in elderly adults with memory complaints (MAPT): a randomised, placebo-controlled trial

Sandrine Andrieu et al.

LANCET NEUROLOGY (2017)

Add to Collection
Article Gastroenterology & Hepatology

The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

Glenn R. Gibson et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)

Add to Collection
Review Cell Biology

Effects of medicinal plants on Alzheimer's disease and memory deficits

Muhammad Akram et al.

NEURAL REGENERATION RESEARCH (2017)

Add to Collection
Article Microbiology

Beef, Chicken, and Soy Proteins in Diets Induce Different Gut Microbiota and Metabolites in Rats

Yingying Zhu et al.

FRONTIERS IN MICROBIOLOGY (2017)

Add to Collection
Review Clinical Neurology

Association of Docosahexaenoic Acid Supplementation With Alzheimer Disease Stage in Apolipoprotein E ε4 Carriers A Review

Hussein N. Yassine et al.

JAMA NEUROLOGY (2017)

Add to Collection
Review Neurosciences

Bile Acid Signaling Pathways from the Enterohepatic Circulation to the Central Nervous System

Kim L. Mertens et al.

FRONTIERS IN NEUROSCIENCE (2017)

Add to Collection
Article Neurosciences

A Complex Interplay of Vitamin B1 and B6 Metabolism with Cognition, Brain Structure, and Functional Connectivity in Older Adults

Kai Jannusch et al.

FRONTIERS IN NEUROSCIENCE (2017)

Add to Collection
Article Multidisciplinary Sciences

Gut microbiome alterations in Alzheimer's disease

Nicholas M. Vogt et al.

SCIENTIFIC REPORTS (2017)

Add to Collection
Review Pharmacology & Pharmacy

Effect of Green Tea Phytochemicals on Mood and Cognition

Christina Dietz et al.

CURRENT PHARMACEUTICAL DESIGN (2017)

Add to Collection
Article Biochemistry & Molecular Biology

Ketone Body Acetoacetate Buffers Methylglyoxal via a Non-enzymatic Conversion during Diabetic and Dietary Ketosis

Trine Salomon et al.

CELL CHEMICAL BIOLOGY (2017)

Add to Collection
Review Nutrition & Dietetics

The Impact of the Mediterranean Diet on the Cognitive Functioning of Healthy Older Adults: A Systematic Review and Meta-Analysis

David G. Loughrey et al.

ADVANCES IN NUTRITION (2017)

Add to Collection
Article Biochemistry & Molecular Biology

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease

Timothy R. Sampson et al.

CELL (2016)

Add to Collection
Review Biochemistry & Molecular Biology

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

Ara Koh et al.

CELL (2016)

Add to Collection
Article Immunology

All-trans retinoic acid (ATRA) prevents lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment in aged rats

Nassima Behairi et al.

JOURNAL OF NEUROIMMUNOLOGY (2016)

Add to Collection
Review Medicine, General & Internal

Alzheimer's disease

Philip Scheltens et al.

LANCET (2016)

Add to Collection
Article Clinical Neurology

Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial

Rafael de la Torre et al.

LANCET NEUROLOGY (2016)

Add to Collection
Review Multidisciplinary Sciences

Diet-microbiota interactions as moderators of human metabolism

Justin L. Sonnenburg et al.

NATURE (2016)

Add to Collection
Article Clinical Neurology

APOE ε4 and the associations of seafood and long-chain omega-3 fatty acids with cognitive decline

Ondine van de Rest et al.

NEUROLOGY (2016)

Add to Collection
Article Nutrition & Dietetics

No Association between Dietary Patterns and Risk for Cognitive Decline in Older Women with 9-Year Follow-Up: Data from the Women's Health Initiative Memory Study

Bernhard Haring et al.

JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS (2016)

Add to Collection
Article Clinical Neurology

MIND diet slows cognitive decline with aging

Martha Clare Morris et al.

ALZHEIMERS & DEMENTIA (2015)

Add to Collection
Article Clinical Neurology

Vagotomy and Subsequent Risk of Parkinson's Disease

Elisabeth Svensson et al.

ANNALS OF NEUROLOGY (2015)

Add to Collection
Article Biochemistry & Molecular Biology

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

Jessica M. Yano et al.

CELL (2015)

Add to Collection
Article Cell Biology

Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

Robert Caesar et al.

CELL METABOLISM (2015)

Add to Collection
Article Food Science & Technology

Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease -amyloid oligomerization

Dongjie Wang et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2015)

Add to Collection
Review Immunology

Innate immunity in Alzheimer's disease

Michael T. Heneka et al.

NATURE IMMUNOLOGY (2015)

Add to Collection
Review Biotechnology & Applied Microbiology

Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties

Laura Marin et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Add to Collection
Article Psychiatry

Serotonin Synthesis and Reuptake in Social Anxiety Disorder A Positron Emission Tomography Study

Andreas Frick et al.

JAMA PSYCHIATRY (2015)

Add to Collection
Article Neurosciences

Acute effects of a dietary non-starch polysaccharide supplement on cognitive performance in healthy middle-aged adults

Talitha Best et al.

NUTRITIONAL NEUROSCIENCE (2015)

Add to Collection
Article Multidisciplinary Sciences

Diet rapidly and reproducibly alters the human gut microbiome

Lawrence A. David et al.

NATURE (2014)

Add to Collection
Review Gastroenterology & Hepatology

Bile acid receptors as targets for drug development

Frank G. Schaap et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2014)

Add to Collection
Article Gastroenterology & Hepatology

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

Colin Hill et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2014)

Add to Collection
Review Nutrition & Dietetics

The Role of Dietary Histone Deacetylases (HDACs) Inhibitors in Health and Disease

Shalome A. Bassett et al.

NUTRIENTS (2014)

Add to Collection
Article Multidisciplinary Sciences

Upregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in mice

Ryoko Kibe et al.

SCIENTIFIC REPORTS (2014)

Add to Collection
Article Biochemistry & Molecular Biology

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

Elaine Y. Hsiao et al.

CELL (2013)

Add to Collection
Editorial Material Gastroenterology & Hepatology

GUT MICROBIOTA Intestinal bacteria influence brain activity in healthy humans

Stephen M. Collins et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2013)

Add to Collection
Review Pharmacology & Pharmacy

The influence of diet on the gut microbiota

Karen P. Scott et al.

PHARMACOLOGICAL RESEARCH (2013)

Add to Collection
Review Clinical Neurology

The blood-brain barrier in health and disease

Richard Daneman

ANNALS OF NEUROLOGY (2012)

Add to Collection
Article Neurosciences

Brain-Targeted Proanthocyanidin Metabolites for Alzheimer's Disease Treatment

Jun Wang et al.

JOURNAL OF NEUROSCIENCE (2012)

Add to Collection
Article Geriatrics & Gerontology

Tocopherols and tocotrienols plasma levels are associated with cognitive impairment

Francesca Mangialasche et al.

NEUROBIOLOGY OF AGING (2012)

Add to Collection
Article Geriatrics & Gerontology

GSPE interferes with tau aggregation in vivo: implication for treating tauopathy

Ismael Santa-Maria et al.

NEUROBIOLOGY OF AGING (2012)

Add to Collection
Article Neurosciences

Sodium Butyrate Improves Memory Function in an Alzheimer's Disease Mouse Model When Administered at an Advanced Stage of Disease Progression

Nambirajan Govindarajan et al.

JOURNAL OF ALZHEIMERS DISEASE (2011)

Add to Collection
Article Multidisciplinary Sciences

Longevity in Mice Is Promoted by Probiotic-Induced Suppression of Colonic Senescence Dependent on Upregulation of Gut Bacterial Polyamine Production

Mitsuharu Matsumoto et al.

PLOS ONE (2011)

Add to Collection
Article Multidisciplinary Sciences

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

Javier A. Bravo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Add to Collection
Article Medicine, Research & Experimental

Kynurenine and its metabolites in Alzheimer's disease patients

E. Gulaj et al.

ADVANCES IN MEDICAL SCIENCES (2010)

Add to Collection
Article Immunology

Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease

Ka Ka Ting et al.

JOURNAL OF NEUROINFLAMMATION (2009)

Add to Collection
Review Immunology

Vitamin effects on the immune system: vitamins A and D take centre stage

J. Rodrigo Mora et al.

NATURE REVIEWS IMMUNOLOGY (2008)

Add to Collection
Article Medicine, General & Internal

Donepezil in patients with severe Alzheimer's disease:: double-blind, parallel-group, placebo-controlled study

B Winblad et al.

LANCET (2006)

Add to Collection
Webinars Posters Questions Hubs Funding Journals Papers Connect Collections Reviewers About Us FAQs Mobile App Privacy Policy Terms of Use
© Peeref 2019-2024. All rights reserved.