☆ 4.7 Article

Stimuli-Responsive Polymer Nanoprobes Intended for Fluorescence-Guided Surgery of Malignant Head-and-Neck Tumors and Metastases

ADVANCED HEALTHCARE MATERIALS (2023)

Related references

Note: Only part of the references are listed.

Article Nanoscience & Nanotechnology

Dye labeling for optical imaging biases drug carriers' biodistribution and tumor uptake

Sarah Schraven et al.

Summary: Biodistribution of nanocarriers with different dye tags was compared, showing that hydrophobic dyes were preferentially taken up by tumor cells. The uptake was actively mediated but not influenced by transporters. Additionally, labeling significantly impacted the tumor accumulation and biodistribution of nanocarriers, emphasizing the need for low-interference dyes and further exploration of dye tags for unbiased results.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2023)

Add to Collection

Review Pharmacology & Pharmacy

Recent progress in NIR-II fluorescence imaging-guided drug delivery for cancer theranostics

Shubham Roy et al.

Summary: Fluorescence imaging in the second near-infrared window (NIR-II) has many advantages, making it a popular choice for imaging-guided drug delivery (IGDD) paradigms. This review discusses the recent progress in NIR-II IGDD-mediated cancer therapeutics, including design approaches, different therapies, and updated platforms. The review also highlights the innovation directions for NIR-II IGDD platforms to improve theranostic outcomes and clinical translation. This review will contribute to the development of safe and efficient NIR-II fluorescence-mediated anticancer drug delivery.

ADVANCED DRUG DELIVERY REVIEWS (2023)

Add to Collection

Article Engineering, Biomedical

Cytarabine nanotherapeutics with increased stability and enhanced lymphoma uptake for tailored highly effective therapy of mantle cell lymphoma

Robert Pola et al.

Summary: The study demonstrates that HPMA-based araC co-polymers show significant anti-lymphoma efficacy in chronically relapsing MCL patients, with long-term disappearance of lymphomas even in cases of patients who relapsed after high-dose araC treatments. This provides a strong preclinical rationale for the use of HPMA-based araC co-polymers in induction, salvage or palliative therapy for MCL patients.

ACTA BIOMATERIALIA (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Acid-responsive HPMA copolymer-bradykinin conjugate enhances tumor-targeted delivery of nanomedicine

Enoch Appiah et al.

Summary: This study designed and synthesized a novel HPMA-based copolymer conjugate of BK, which showed tumor-selective action and improved accumulation of nanomedicines in the tumor, resulted in enhanced intratumoral blood flow and increased tumor deposition of nanomedicines.

JOURNAL OF CONTROLLED RELEASE (2021)

Add to Collection

Article Pharmacology & Pharmacy

Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors

Robert Pola et al.

PHARMACEUTICS (2020)

Add to Collection

Review Oncology

A comprehensive review of surgical margin in oral squamous cell carcinoma highlighting the significance of tumor-free surgical margins

Mamata Kamat et al.

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS (2019)

Add to Collection

Article Biochemistry & Molecular Biology

Polymer Cancerostatics Targeted with an Antibody Fragment Bound via a Coiled Coil Motif: In Vivo Therapeutic Efficacy against Murine BCL1 Leukemia

Michal Pechar et al.

MACROMOLECULAR BIOSCIENCE (2018)

Add to Collection

Review Biochemistry & Molecular Biology

HPMA Copolymer-Drug Conjugates with Controlled Tumor-Specific Drug Release

Petr Chytil et al.

MACROMOLECULAR BIOSCIENCE (2018)

Add to Collection

Article Otorhinolaryngology

Near-infrared fluorescence imaging-guided surgery improves recurrence-free survival rate in novel orthotopic animal model of head and neck squamous cell carcinoma

Ihab Atallah et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2016)

Add to Collection

Article Chemistry, Multidisciplinary

The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia

Barbora Tomalova et al.

JOURNAL OF CONTROLLED RELEASE (2016)

Add to Collection

Article Oncology

Global cancer surgery: delivering safe, affordable, and timely cancer surgery

Richard Sullivan et al.

LANCET ONCOLOGY (2015)

Add to Collection

Review Surgery

Recent advances in near-infrared fluorescence-guided imaging surgery using indocyanine green

Tsutomu Namikawa et al.

SURGERY TODAY (2015)

Add to Collection

Article Gastroenterology & Hepatology

Clinical applications of 5-aminolevulinic acid-mediated fluorescence for gastric cancer

Tsutomu Namikawa et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2015)

Add to Collection

Article Chemistry, Multidisciplinary

Dual fluorescent HPMA copolymers for passive tumor targeting with pH- sensitive drug release II: Impact of release rate on biodistribution

Petr Chytil et al.

JOURNAL OF CONTROLLED RELEASE (2013)

Add to Collection

Article Biochemistry & Molecular Biology

Dual Fluorescent HPMA Copolymers for Passive Tumor Targeting with pH-Sensitive Drug Release: Synthesis and Characterization of Distribution and Tumor Accumulation in Mice by Noninvasive Multispectral Optical Imaging

Stefan Hoffmann et al.

BIOMACROMOLECULES (2012)

Add to Collection

Article Chemistry, Multidisciplinary

HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity

Tomas Etrych et al.

JOURNAL OF CONTROLLED RELEASE (2012)

Add to Collection

Article Polymer Science

N-(2-hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin.: I.: New synthesis, physicochemical characterization and preliminary biological evaluation

Tomas Etrych et al.

JOURNAL OF APPLIED POLYMER SCIENCE (2008)

Add to Collection

Article Polymer Science

Reversible addition-fragmentation chain transfer polymerization: End group modification for functionalized polymers and chain transfer agent recovery

S Perrier et al.

MACROMOLECULES (2005)

Add to Collection

Article Biochemical Research Methods

Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: Model studies of enzymatic drug release and antigen-specific in vitro anticancer activity

GM Dubowchik et al.

BIOCONJUGATE CHEMISTRY (2002)

Add to Collection

Article Chemistry, Multidisciplinary

Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes

B Ríhová et al.

JOURNAL OF CONTROLLED RELEASE (2001)

Add to Collection

Article Chemistry, Multidisciplinary

New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage:: synthesis and preliminary in vitro and in vivo biological properties

T Etrych et al.

JOURNAL OF CONTROLLED RELEASE (2001)

Add to Collection

Article Chemistry, Multidisciplinary

Polymeric drugs based on conjugates of synthetic and natural macromolecules I.: Synthesis and physico-chemical characterisation

K Ulbrich et al.

JOURNAL OF CONTROLLED RELEASE (2000)

Add to Collection

Article Chemistry, Multidisciplinary

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

H Maeda et al.

JOURNAL OF CONTROLLED RELEASE (2000)

Add to Collection

© Peeref 2019-2024. All rights reserved.