4.7 Article

Identification of a hypoxia-related gene prognostic signature in colorectal cancer based on bulk and single-cell RNA-seq

Related references

Note: Only part of the references are listed.
Article Medicine, Research & Experimental

A pan-cancer analysis of molecular characteristics and oncogenic role of hexokinase family genes in human tumors

Mingzhe Jiang et al.

Summary: The study systematically analyzed the molecular changes and clinical correlations of HK family genes in 33 types of cancer from over 10,000 subjects, revealing extensive genetic changes in HK family genes with potential for predicting prognosis and therapeutic efficacy, as well as identifying HK1, HK2, and HK3 as potential oncogenes in various cancer types.

LIFE SCIENCES (2021)

Article Oncology

Crosstalk between YAP and TGFβ regulates SERPINE1 expression in mesenchymal lung cancer cells

Hyeon-Joon Kong et al.

Summary: This study found that in mesenchymal lung cancer cells, the expression of SERPINE1 is regulated by the YAP pathway, with TGF-beta treatment enhancing TGF-beta-mediated SERPINE1 expression. The crosstalk between the TGF-beta and YAP pathways underlies SERPINE1 expression in mesenchymal cancer cells.

INTERNATIONAL JOURNAL OF ONCOLOGY (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Oncology

Identification of Five Glycolysis-Related Gene Signature and Risk Score Model for Colorectal Cancer

Jun Zhu et al.

Summary: The study highlights the clinical significance of glycolysis in colorectal cancer and constructs a glycolysis-related prognostic model, providing a promising target for glycolysis regulation in CRC.

FRONTIERS IN ONCOLOGY (2021)

Article Surgery

CircDUSP16 Contributes to Cell Development in Esophageal Squamous Cell Carcinoma by Regulating miR-497-5p/TKTL1 Axis

Limin Ma et al.

Summary: In this study, circDUSP16 was found to regulate TKTL1 expression by sponging miR-497-5p in esophageal squamous cell carcinoma, suppressing cell growth, invasion, and glycolysis. Overexpression of miR-497-5p inhibited the progression of ESCC cells under hypoxia conditions. These findings shed light on the potential therapeutic targets for ESCC treatment.

JOURNAL OF SURGICAL RESEARCH (2021)

Article Medicine, Research & Experimental

Glycolysis promotes the progression of pancreatic cancer and reduces cancer cell sensitivity to gemcitabine

Shangnan Dai et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Article Medicine, Research & Experimental

Prognostic Value of Enolase Gene Family in Colon Cancer

Xiaohang Pan et al.

MEDICAL SCIENCE MONITOR (2020)

Article Pharmacology & Pharmacy

Esculetin Inhibits Cancer Cell Glycolysis by Binding Tumor PGK2, GPD2, and GPI

Song-Tao Wu et al.

FRONTIERS IN PHARMACOLOGY (2020)

Review Endocrinology & Metabolism

The VHL/HIF Axis in the Development and Treatment of Pheochromocytoma/Paraganglioma

Song Peng et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Review Medicine, General & Internal

Colorectal cancer

Evelien Dekker et al.

LANCET (2019)

Review Biochemistry & Molecular Biology

Role of hypoxia in cancer therapy by regulating the tumor microenvironment

Xinming Jing et al.

MOLECULAR CANCER (2019)

Article Biochemistry & Molecular Biology

Overexpression and Selective Anticancer Efficacy of ENO3 in STK11 Mutant Lung Cancers

Choa Park et al.

MOLECULES AND CELLS (2019)

Review Endocrinology & Metabolism

Roles of Aldolase Family Genes in Human Cancers and Diseases

Yu-Chan Chang et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2018)

Review Biochemistry & Molecular Biology

Role of hypoxia-induced exosomes in tumor biology

Chuchu Shao et al.

MOLECULAR CANCER (2018)

Article Biotechnology & Applied Microbiology

Genome-scale analysis identifies SERPINE1 and SPARC as diagnostic and prognostic biomarkers in gastric cancer

Ping Liao et al.

ONCOTARGETS AND THERAPY (2018)

Review Oncology

Metabolic phenotype of bladder cancer

Francesco Massari et al.

CANCER TREATMENT REVIEWS (2016)

Editorial Material Multidisciplinary Sciences

Colorectal cancer

Herb Brody

NATURE (2015)

Article Biochemical Research Methods

Robust enumeration of cell subsets from tissue expression profiles

Aaron M. Newman et al.

NATURE METHODS (2015)

Article Multidisciplinary Sciences

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

A Subramanian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)