Structural, optical, and cytotoxicity studies of laser irradiated ZnO doped borate bioactive glasses

Borate glasses (BG) doped with different amounts of ZnO (0-0.6 mol%) were formed by the traditional melt quenching technique. The different glasses so made were characterized using different characterization techniques such as X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), and UV-Vis absorption optical properties. The XRD patterns showed an amorphous structure with one broad peak at 2 nu = 29 degrees, while the phonons bands were studied in terms of the FTIR bands. Optical properties of the glasses were studied using UV-Vis absorption spectra in the range 190-1100 nm, in which the prominent band lies at about 261.5 nm of peak position, from which the bandgab (E-g) was calculated from its edge using Tauc's plot, with E-g similar to 3.5 eV. The laser irradiation showed no significant changes in the absorption bands, despite a significant change observed in the amorphous behavior in the XRD pattern. The cell viability was performed for two samples of the BG and 0.6 mol% ZnO doped using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay method. The result showed better cell viability and low toxicity. So, ZnO doped BG can be used in various biomedical applications.

Automated summary

Borate glasses doped with different amounts of ZnO were characterized using various techniques and found to have an amorphous structure and a prominent absorption band at 261.5 nm with an energy gap of approximately 3.5 eV. The doped glass also showed better cell viability and low toxicity, indicating its potential for biomedical applications.