Long-term changes in the choroidal thickness in patients with unilateral central retinal vein occlusion

The purpose of this study was to investigate the long-term changes in the choroidal thickness in central retinal vein occlusion (CRVO) following anti-vascular endothelial growth factor (VEGF) treatment. This retrospective study included 41 eyes from 41 patients with treatment-naive unilateral CRVO. We compared the best-corrected visual acuity (BCVA), subfoveal choroidal thickness (SFCT), and central macular thickness (CMT) of CRVO eyes with those of fellow eyes at baseline, 12 months, and 24 months. Baseline SFCT was significantly higher in CRVO eyes than in fellow eyes (p < 0.001); however, there was no significant difference in the SFCT between CRVO eyes and fellow eyes at 12 months and 24 months. When compared with baseline SFCT, SFCT significantly decreased at 12 months and 24 months in CRVO eyes (all p < 0.001). In patients with unilateral CRVO, SFCT in the CRVO eye was significantly thicker than in the fellow eye at baseline, and after 12 months and 24 months, there was no difference from the fellow eye.

Automated summary

The purpose of this study was to investigate the long-term changes in choroidal thickness in central retinal vein occlusion (CRVO) after anti-vascular endothelial growth factor (VEGF) treatment. The study included 41 patients with treatment-naive unilateral CRVO. The results showed that the subfoveal choroidal thickness (SFCT) in CRVO eyes significantly decreased at 12 months and 24 months compared to baseline.