☆ 4.7 Article

Resveratrol Alleviates Diabetic Periodontitis-Induced Alveolar Osteocyte Ferroptosis Possibly via Regulation of SLC7A11/GPX4

NUTRIENTS (2023)

Related references

Note: Only part of the references are listed.
Article Food Science & Technology

Quercetin and resveratrol inhibit ferroptosis independently of Nrf2-ARE activation in mouse hippocampal HT22 cells

Kosuke Kato et al.

Summary: Oxidative stress plays a central role in various cell death pathways, including ferroptosis. Phytochemicals, such as curcumin, quercetin, and resveratrol, protect cells against ferroptosis by reducing oxidative stress independently of the Nrf2-ARE pathway. Quercetin and resveratrol also inhibit the iron-catalyzed generation of hydroxyl radicals.

FOOD AND CHEMICAL TOXICOLOGY (2023)

Add to Collection
Review Biochemistry & Molecular Biology

Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis

Luc Rochette et al.

Summary: Regulated cell death (RCD), including ferroptosis, plays a significant role in development, tissue homeostasis, and disease occurrence. Ferroptosis is a type of regulated necrosis dependent on reactive oxygen species (ROS) and lipid peroxidation. Iron accumulation and lipid peroxidation are central events leading to ferroptosis, and organelles such as mitochondria and lysosomes are involved in regulating iron metabolism and redox imbalance. This review provides an overview of lipid peroxidation and key components involved in the ferroptotic cascade.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Add to Collection
Article Biochemistry & Molecular Biology

Morphometric Changes of Osteocyte Lacunar in Diabetic Pig Mandibular Cancellous Bone

Sheng Yao et al.

Summary: Osteocytes play a crucial role in bone metabolism and their interactions with the microenvironment can affect cellular and lacunar morphology. This study developed a novel method to analyze osteocytes/lacunae and used it to evaluate morphological changes in diabetic pig mandibular bone. Using backscattered electron scanning microscopy, the size of osteocyte lacunae was found to be significantly decreased in the diabetic group.

BIOMOLECULES (2023)

Add to Collection
Article Biochemistry & Molecular Biology

Inhibition of ferroptosis by icariin treatment attenuates excessive ethanol consumption-induced atrial remodeling and susceptibility to atrial fibrillation, role of SIRT1

Li-Ming Yu et al.

Summary: This study aimed to explore the pharmacological effects of icariin on ethanol-induced atrial remodeling and the underlying mechanisms involving SIRT1 signaling. It was found that excessive ethanol administration caused significant atrial damage, which was reversed by icariin treatment. Icariin protected against atrial damage by inhibiting ferroptosis via activation of the SIRT1 signaling pathway. These findings suggest that icariin may have potential applications as a prophylactic/therapeutic drug for atrial fibrillation.

APOPTOSIS (2023)

Add to Collection
Article Pharmacology & Pharmacy

Resveratrol protected acrolein-induced ferroptosis and insulin secretion dysfunction via ER-stress- related PERK pathway in MIN6 cells

Xinhao Zhang et al.

Summary: Acrolein, a common food and environmental pollutant, induces ferroptosis in pancreatic beta cells, leading to dysfunction. Endoplasmic reticulum stress plays a critical role in acrolein-induced ferroptosis. Resveratrol can alleviate ER stress and protect pancreatic cells from acrolein-induced damage.

TOXICOLOGY (2022)

Add to Collection
Review Endocrinology & Metabolism

Distinct Glucocorticoid Receptor Actions in Bone Homeostasis and Bone Diseases

Sooyeon Lee et al.

Summary: Glucocorticoids (GCs) regulate bone homeostasis in a cell-type specific manner and disturbance of circadian rhythm by exogenous GCs treatment can hamper bone integrity. GC signaling is also important for fracture healing and rheumatoid arthritis.

FRONTIERS IN ENDOCRINOLOGY (2022)

Add to Collection
Article Biology

Pathogenic Molecular Mechanisms in Periodontitis and Peri-Implantitis: Role of Advanced Glycation End Products

Grigorios Plemmenos et al.

Summary: Advanced Glycation End Products (AGEs) accumulation in periodontal tissues under hyperglycemic conditions contributes to periodontal destruction. AGEs affect periodontal ligament cells through direct or indirect mechanisms, playing a significant role in periodontitis and peri-implantitis. Inhibition of AGEs, along with dental biofilm removal and diabetes regulation, shows promise in patient management.

LIFE-BASEL (2022)

Add to Collection
Article Cell Biology

Protecting mitochondria via inhibiting VDAC1 oligomerization alleviates ferroptosis in acetaminophen-induced acute liver injury

Baolin Niu et al.

Summary: APAP overdose can lead to ferroptosis, and protecting mitochondria can alleviate APAP-induced hepatocyte ferroptosis by restoring ceramide and cardiolipin content. Specifically, inhibiting VDAC1 oligomerization can protect hepatocytes from AILI damage by restoring ceramide and cardiolipin levels.

CELL BIOLOGY AND TOXICOLOGY (2022)

Add to Collection
Article Pharmacology & Pharmacy

Mechanism and effects of artesunate on the liver function of rats with type 1 diabetic periodontitis

Shuoqiu Bai et al.

Summary: This study investigated the effects of diabetic periodontitis on liver function and found that artesunate can improve liver function. Artesunate protects diabetes-related liver function by inhibiting the expression of inflammatory factors, offering a new approach for diabetes treatment.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2022)

Add to Collection
Review Biochemistry & Molecular Biology

Ferroptosis at the intersection of lipid metabolism and cellular signaling

Deguang Liang et al.

Summary: This review provides a comprehensive analysis of the mechanisms and signaling pathways involved in ferroptosis, focusing on the impact of lipid metabolism and the potential for therapeutic strategies targeting this interaction.

MOLECULAR CELL (2022)

Add to Collection
Review Dentistry, Oral Surgery & Medicine

Oral microbiota in human systematic diseases

Xian Peng et al.

Summary: Oral bacteria directly influence dental caries and periodontal diseases, and the dynamic oral microbiota reflects immune and metabolic information and status through communication between the oral cavity and systemic organs. The oral cavity acts as an important interaction window between the human body and the environment, and the microbial composition in different sites is regulated by complex signaling, hosts, and external environmental factors.

INTERNATIONAL JOURNAL OF ORAL SCIENCE (2022)

Add to Collection
Article Biochemistry & Molecular Biology

Diabetic oxidative stress-induced telomere damage aggravates periodontal bone loss in periodontitis

Lu Tang et al.

Summary: Periodontitis, a common complication of diabetes, is exacerbated by oxidative stress-induced damage to telomeres and senescence of periodontal ligament stem cells (PDLSCs), ultimately leading to impaired bone tissue regeneration and reconstruction.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022)

Add to Collection
Article Medicine, General & Internal

Resveratrol decreases local inflammatory markers and systemic endotoxin in patients with aggressive periodontitis

Qiang Zhang et al.

Summary: The study found that resveratrol has an inhibitory effect on inflammation in patients with periodontitis, improving their periodontal condition and reducing systemic inflammation. The ideal dosage for patients with periodontitis is 500mg/d.

MEDICINE (2022)

Add to Collection
Review Rheumatology

Mechanisms of joint destruction in rheumatoid arthritis - immune cell-fibroblast-bone interactions

Noriko Komatsu et al.

Summary: This review provides an overview of the mechanisms contributing to joint damage in rheumatoid arthritis (RA) and discusses the interactions among immune cells, fibroblasts, and bone. The authors highlight the importance of understanding these mechanisms for the development of novel therapies in RA.

NATURE REVIEWS RHEUMATOLOGY (2022)

Add to Collection
Article Cell Biology

Activation of SIRT1 Alleviates Ferroptosis in the Early Brain Injury after Subarachnoid Hemorrhage

Bin Yuan et al.

Summary: Ferroptosis is involved in the pathogenesis of early brain injury (EBI) after subarachnoid hemorrhage (SAH), and inhibiting ferroptosis can alleviate brain damage. SIRT1 activation can suppress SAH-induced ferroptosis.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2022)

Add to Collection
Article Dentistry, Oral Surgery & Medicine

Healing effects of monomer and dimer resveratrol in a mouse periodontitis model

Eri Ikeda et al.

Summary: The study demonstrated that resveratrol dimer had greater periodontal bone healing effects compared to the monomeric form. Both forms of resveratrol treatment were associated with activation of the antioxidant Nrf2 pathway, while the dimer group also showed reduction in proinflammatory cytokine IL-1β.

BMC ORAL HEALTH (2022)

Add to Collection
Article Immunology

Identification of cross-talk pathways and ferroptosis-related genes in periodontitis and type 2 diabetes mellitus by bioinformatics analysis and experimental validation

Shengyuan Pan et al.

Summary: This study investigates the relationship between periodontitis and type 2 diabetes mellitus (T2DM), identifying ferroptosis-related genes and potential drug targets. The findings suggest that targeting ferroptosis may be a crucial approach in the treatment of periodontitis with T2DM, and IL-1 beta, IL-6, NFE2L2, and ALOX5 are identified as core ferroptosis-related genes. Additionally, 13 potential drugs, including Echinacea and Ibudilast, are screened out.

FRONTIERS IN IMMUNOLOGY (2022)

Add to Collection
Review Immunology

Impact of the host response and osteoblast lineage cells on periodontal disease

Mi Zhou et al.

Summary: Periodontitis is caused by an immune response to bacterial dysbiosis, leading to bone resorption and limited bone repair processes.

FRONTIERS IN IMMUNOLOGY (2022)

Add to Collection
Article Psychiatry

Agreement between patients and mental healthcare providers on unmet care needs in child and adolescent psychiatry

Richard Vijverberg et al.

Summary: In mental health care, patients and their care providers may have significantly different views on the care needs of patients, particularly in young patients. Patients typically report fewer unmet care needs compared to care providers.

SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY (2021)

Add to Collection
Article Biochemistry & Molecular Biology

Lipid Peroxidation, GSH Depletion, and SLC7A11 Inhibition are Common Causes of EMT and Ferroptosis in A549 Cells, but Different in Specific Mechanisms

Lulu Sun et al.

Summary: Evidence suggests common factors between ferroptosis and pulmonary fibrosis, such as changes in GSH levels and SLC7A11 expression. However, they differ in specific mechanisms. Further study is needed to understand the exact effects of GPX4 in A549 cells undergoing EMT and ferroptosis.

DNA AND CELL BIOLOGY (2021)

Add to Collection
Review Dentistry, Oral Surgery & Medicine

Current concepts in the management of periodontitis

TaeHyun Kwon et al.

Summary: Periodontitis is a common disorder that affects a large percentage of adults globally, with a multifactorial etiology and potential for tooth loss and reduced quality of life. Successful management involves careful diagnosis, treatment including non-surgical and surgical therapies, and long-term maintenance to prevent disease progression and tooth loss.

INTERNATIONAL DENTAL JOURNAL (2021)

Add to Collection
Review Biochemistry & Molecular Biology

Anti-Inflammatory Action and Mechanisms of Resveratrol

Tiantian Meng et al.

Summary: Resveratrol, a natural phytoalexin polyphenol, demonstrates antioxidant, anti-inflammatory, and anti-carcinogenic properties, with the ability to modulate inflammatory responses and exhibit immunomodulatory function both in vivo and in vitro.

MOLECULES (2021)

Add to Collection
Review Cell Biology

Ferroptosis: mechanisms, biology and role in disease

Xuejun Jiang et al.

Summary: Ferroptosis, as a form of regulated cell death driven by iron-dependent phospholipid peroxidation, has seen significant growth in research in recent years. Studies have focused on molecular mechanisms, regulation, and functions of ferroptosis, linking this cell death modality to various pathologies and proposing its roles in normal physiology and potential therapeutic targeting.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)

Add to Collection
Article Plant Sciences

Cytotoxicity of apigenin toward multiple myeloma cell lines and suppression of iNOS and COX-2 expression in STAT1-transfected HEK293 cells

Aveen N. Adham et al.

Summary: Apigenin shows potential as a candidate for multiple myeloma treatment, inhibiting the STAT1/COX-2/iNOS signaling pathway and promoting apoptosis in cancer cells. It also exhibits cytotoxic activity against a range of tumor cell lines.

PHYTOMEDICINE (2021)

Add to Collection
Review Biochemistry & Molecular Biology

Periodontitis and Gestational Diabetes Mellitus: A Potential Inflammatory Vicious Cycle

Maria Jose Bendek et al.

Summary: Periodontitis is a chronic inflammatory immune disease that can result in periodontal tissue destruction and tooth loss in susceptible hosts, leading to a systemic pro-inflammatory state associated with increased risk of various systemic diseases like type 2 diabetes. The mechanistic link between periodontitis and gestational diabetes mellitus remains unclear, with potential involvement of new molecular participants such as extracellular vesicles and non-coding RNAs in the association.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection
Article Endocrinology & Metabolism

Role of ferroptosis in the process of diabetes-induced endothelial dysfunction

Er-Fei Luo et al.

Summary: Ferroptosis is involved in endothelial dysfunction caused by diabetes, with activation of the p53-xCT-GSH axis playing a crucial role in endothelial cell ferroptosis and dysfunction.

WORLD JOURNAL OF DIABETES (2021)

Add to Collection
Article Cell Biology

RSL3 Drives Ferroptosis through NF-κB Pathway Activation and GPX4 Depletion in Glioblastoma

Shengbiao Li et al.

Summary: The study revealed that RSL3 induced ferroptosis in glioblastoma cells by increasing lipid ROS concentration and downregulating ferroptosis-related proteins. Activation of the NF-kappa B pathway by RSL3 played a key role in this process, and inhibition of this pathway alleviated ferroptosis. Furthermore, the combination of NF-kappa B pathway activation and GPX4 silencing effectively induced ferroptosis in glioblastoma cells, suggesting a potential therapeutic strategy for glioblastoma treatment.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)

Add to Collection
Article Endocrinology & Metabolism

Ferroptosis Enhanced Diabetic Renal Tubular Injury via HIF-1α/HO-1 Pathway in db/db Mice

Xiaomeng Feng et al.

Summary: The study found that ferroptosis aggravated diabetic nephropathy and damaged renal tubules in db/db mice through the HIF-1 alpha/HO-1 pathway.

FRONTIERS IN ENDOCRINOLOGY (2021)

Add to Collection
Article Nutrition & Dietetics

Astaxanthin Inhibits Diabetes-Triggered Periodontal Destruction, Ameliorates Oxidative Complications in STZ-Injected Mice, and Recovers Nrf2-Dependent Antioxidant System

Govinda Bhattarai et al.

Summary: Numerous studies have shown that supplementation with astaxanthin (ASTX) can ameliorate periodontal destruction and systemic complications in diabetic mice, including restoring normal water and feed consumptions, reducing lethality, and inhibiting inflammatory factors in the periodontium. ASTX also enhances antioxidant enzyme activity and inhibits oxidative stress in diabetic mice.

NUTRIENTS (2021)

Add to Collection
Article Cell Biology

Downregulation of Macrophage-Specific Act-1 Intensifies Periodontitis and Alveolar Bone Loss Possibly via TNF/NF-κB Signaling

Janak L. Pathak et al.

Summary: The study revealed that downregulation of macrophage-specific Act1 worsened periodontitis, alveolar bone loss, macrophage infiltration, inflammation, and M1 macrophage polarization. Diseased periodontal tissue in anti-Act1 mice showed more severe macrophage infiltration and M1 macrophage polarization. These findings indicate the distinct role of macrophage-specific Act1 in the pathophysiology of periodontitis possibly through the TNF/NF-kappa B signaling pathway.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Add to Collection
Review Immunology

Periodontal Disease: The Good, The Bad, and The Unknown

Lea M. Sedghi et al.

Summary: Periodontal disease is characterized by the dysbiosis of oral microbiota, inflammatory responses, and tissue destruction, driven by key pathogenic microbes and sustained gingival inflammation. Recent studies have identified previously unknown microbial species and immunological mechanisms as important contributors to disease progression, alongside systemic host factors like autoimmune disorders and diet. This expanded understanding highlights the bidirectional relationship between oral health and systemic diseases.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Add to Collection
Review Immunology

Gut-Bone Axis: A Non-Negligible Contributor to Periodontitis

Xiaoyue Jia et al.

Summary: Periodontitis is a polymicrobial infectious disease characterized by alveolar bone loss, with systemic diseases or local infections promoting its development. Gut microbiota plays a crucial role in bone health through the gut-alveolar-bone axis, potentially affecting periodontitis through microbial translocation and immune responses.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Add to Collection
Review Cardiac & Cardiovascular Systems

The role of oral microbiome in respiratory health and diseases

Janak L. Pathak et al.

Summary: The oral cavity harbors a diverse microbiome crucial for maintaining oral health, but disruption of oral microbial balance can lead to various oral diseases and is linked to respiratory diseases. The oral microbiome may play a significant role in respiratory conditions such as chronic obstructive pulmonary disease, highlighting the importance of further research on the oral microbiome for novel therapeutic approaches.

RESPIRATORY MEDICINE (2021)

Add to Collection
Article Cell & Tissue Engineering

Effect of TNF-α and IL-6 on Compact Bone-Derived Cells

Yiming Zhang et al.

Summary: This study highlights the important role of IL-6 in modulating the efficacy of bone tissue engineering, showing both positive and negative effects on CBDCs. TNF-alpha, on the other hand, significantly suppresses the expression of osteogenic markers. In vivo experiments demonstrate a correlation between high IL-6 expression and new bone formation, while TNF-alpha expression does not show notable differences.

TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2021)

Add to Collection
Review Dentistry, Oral Surgery & Medicine

Periodontitis and diabetes mellitus co-morbidity: A molecular dialogue

Anthony Luong et al.

Summary: Type 2 diabetes mellitus and periodontitis have complex biological interactions, characterized by chronic inflammation and oxidative stress. Uncontrolled diabetes is often associated with severe periodontitis, with shifts in oral microbiome composition and host inflammatory responses playing crucial roles in both diseases.

JOURNAL OF ORAL BIOSCIENCES (2021)

Add to Collection
Article Dentistry, Oral Surgery & Medicine

Hyperglycemia modulates M1/M2 macrophage polarization via reactive oxygen species overproduction in ligature-induced periodontitis

Bo Zhang et al.

Summary: The study found that high glucose could polarize macrophages toward M1 macrophages via overproducing ROS, which may be responsible for aggravated periodontal damage in periodontitis under diabetic condition. Inhibiting M1 macrophages and restoring M2 macrophages by ROS scavenger is potentially a adjunct treatment strategy for diabetic periodontitis.

JOURNAL OF PERIODONTAL RESEARCH (2021)

Add to Collection
Review Dentistry, Oral Surgery & Medicine

Association between metabolic syndrome and periodontitis: The role of lipids, inflammatory cytokines, altered host response, and the microbiome

Flavia Q. Pirih et al.

Summary: Periodontitis is associated with metabolic syndrome, diabetes, and cardiovascular disease, with evidence suggesting that these conditions can alter the oral microbiome. Studies indicate an interrelationship between periodontitis and metabolic syndrome, where periodontitis may contribute to or worsen metabolic syndrome. Additional research is needed to fully comprehend the impact of these conditions on each other.

PERIODONTOLOGY 2000 (2021)

Add to Collection
Review Immunology

Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

George Hajishengallis et al.

Summary: Periodontitis is causally linked to the development of other chronic inflammatory diseases outside the oral mucosa, and intervention studies have shown that local treatment of periodontitis can ameliorate surrogate markers of comorbid conditions. Experimental animal studies have further strengthened the potential causal link by establishing biologically plausible and clinically consistent mechanisms. Understanding the impact of disseminated periodontal pathogens and systemic inflammation associated with periodontitis on extra-oral pathologies may lead to new therapeutic options to reduce the risk of periodontitis-associated comorbidities.

NATURE REVIEWS IMMUNOLOGY (2021)

Add to Collection
Article Biochemistry & Molecular Biology

Fibroblast-secreted trophic factors contribute with ECM remodeling stimulus and upmodulate osteocyte gene markers in osteoblasts

Celio Jr da Costa Fernandes et al.

BIOCHIMIE (2020)

Add to Collection
Article Endocrinology & Metabolism

LPS-induced premature osteocyte senescence: Implications in inflammatory alveolar bone loss and periodontal disease pathogenesis

Ruben Aquino-Martinez et al.

BONE (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Ferrostatin-1 alleviates lipopolysaccharide-induced acute lung injury via inhibiting ferroptosis

Pengfei Liu et al.

CELLULAR & MOLECULAR BIOLOGY LETTERS (2020)

Add to Collection
Article Cell Biology

Reduction of SOST gene promotes bone formation through the Wnt/β-catenin signalling pathway and compensates particle-induced osteolysis

Zai Hang Zhang et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)

Add to Collection
Article Cell Biology

Ferroptosis involves in intestinal epithelial cell death in ulcerative colitis

Minyi Xu et al.

CELL DEATH & DISEASE (2020)

Add to Collection
Review Endocrinology & Metabolism

Impact of diabetes mellitus simulations on bone cell behavior through in vitro models

Yihan Li et al.

JOURNAL OF BONE AND MINERAL METABOLISM (2020)

Add to Collection
Article Cell & Tissue Engineering

Resveratrol counteracts IL-1β-mediated impairment of extracellular matrix deposition in 3D articular chondrocyte constructs

Sebastian Frischholz et al.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2020)

Add to Collection
Review Dentistry, Oral Surgery & Medicine

Diabetes as a risk factor for periodontal disease-plausible mechanisms

David Polak et al.

PERIODONTOLOGY 2000 (2020)

Add to Collection
Review Medicine, Research & Experimental

The emerging role of ferroptosis in inflammation

Yitian Sun et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Add to Collection
Review Biochemistry & Molecular Biology

Osteocyte-Related Cytokines Regulate Osteoclast Formation and Bone Resorption

Hideki Kitaura et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Add to Collection
Review Endocrinology & Metabolism

The Osteocyte as the New Discovery of Therapeutic Options in Rare Bone Diseases

Janak L. Pathak et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Add to Collection
Article Dentistry, Oral Surgery & Medicine

Epidemiologic relationship between periodontitis and type 2 diabetes mellitus

Chen-zhou Wu et al.

BMC ORAL HEALTH (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Advanced glycation end products (AGEs) synergistically potentiated the proinflammatory action of lipopolysaccharide (LPS) and high mobility group box-1 (HMGB1) through their direct interactions

Masahiro Watanabe et al.

MOLECULAR BIOLOGY REPORTS (2020)

Add to Collection
Review Medicine, Research & Experimental

The roles of osteocytes in alveolar bone destruction in periodontitis

Xiaofei Huang et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2020)

Add to Collection
Article Cell Biology

Melatonin Suppresses Ferroptosis Induced by High Glucose via Activation of the Nrf2/HO-1 Signaling Pathway in Type 2 Diabetic Osteoporosis

Hongdong Ma et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)

Add to Collection
Article Biochemistry & Molecular Biology

Ferritinophagy-mediated ferroptosis is involved in sepsis-induced cardiac injury

Ning Li et al.

FREE RADICAL BIOLOGY AND MEDICINE (2020)

Add to Collection
Article Endocrinology & Metabolism

CSF-1 in Osteocytes Inhibits Nox4-mediated Oxidative Stress and Promotes Normal Bone Homeostasis

Sherry L. Werner et al.

JBMR PLUS (2020)

Add to Collection
Review Pharmacology & Pharmacy

Pro-inflammatory Cytokines: Cellular and Molecular Drug Targets for Glucocorticoid-induced-osteoporosis via Osteocyte

Tiantian Wang et al.

CURRENT DRUG TARGETS (2019)

Add to Collection
Review Biochemistry & Molecular Biology

Association between periodontal pathogens and systemic disease

Fiona Q. Bui et al.

BIOMEDICAL JOURNAL (2019)

Add to Collection
Article Multidisciplinary Sciences

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

Yilong Zou et al.

NATURE COMMUNICATIONS (2019)

Add to Collection
Article Dentistry, Oral Surgery & Medicine

Synergistic alveolar bone resorption by diabetic advanced glycation end products and mechanical forces

Jung-Sun Moon et al.

JOURNAL OF PERIODONTOLOGY (2019)

Add to Collection
Article Endocrinology & Metabolism

Hyperglycemia Induces Osteoclastogenesis and Bone Destruction Through the Activation of Ca2+/Calmodulin-Dependent Protein Kinase II

Yanxin Shen et al.

CALCIFIED TISSUE INTERNATIONAL (2019)

Add to Collection
Article Medicine, General & Internal

Effects of periodontal disease on systemic health

R. Hegde et al.

DM DISEASE-A-MONTH (2019)

Add to Collection
Article Dentistry, Oral Surgery & Medicine

An Adiponectin Receptor Agonist Reduces Type 2 Diabetic Periodontitis

X. Wu et al.

JOURNAL OF DENTAL RESEARCH (2019)

Add to Collection
Review Dentistry, Oral Surgery & Medicine

The Oral Microbiota Is Modified by Systemic Diseases

D. T. Graves et al.

JOURNAL OF DENTAL RESEARCH (2019)

Add to Collection
Article Biochemistry & Molecular Biology

Carbonic anhydrase III protects osteocytes from oxidative stress

Chao Shi et al.

FASEB JOURNAL (2018)

Add to Collection
Article Dentistry, Oral Surgery & Medicine

Osteocytes play an important role in experimental periodontitis in healthy and diabetic mice through expression of RANKL

Dana T. Graves et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2018)

Add to Collection
Article Biochemical Research Methods

Capillary-based chemiluminescence immunoassay for C-reactive protein with portable imaging device

Haiying Shen et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2018)

Add to Collection
Review Nutrition & Dietetics

Health Effects of Resveratrol: Results from Human Intervention Trials

Sonia L. Ramirez-Garza et al.

NUTRIENTS (2018)

Add to Collection
Article Immunology

Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway

Cathleen Holze et al.

NATURE IMMUNOLOGY (2018)

Add to Collection
Article Multidisciplinary Sciences

Tumor necrosis factor-α antagonist diminishes osteocytic RANKL and sclerostin expression in diabetes rats with periodontitis

Ji-Hye Kim et al.

PLOS ONE (2017)

Add to Collection
Article Medicine, General & Internal

Periodontal diseases

Denis F. Kinane et al.

NATURE REVIEWS DISEASE PRIMERS (2017)

Add to Collection
Review Multidisciplinary Sciences

Therapeutic applications of resveratrol and its derivatives on periodontitis

Yu-Tang Chin et al.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2017)

Add to Collection
Article Microbiology

Diabetes Enhances IL-17 Expression and Alters the Oral Microbiome to Increase Its Pathogenicity

E. Xiao et al.

CELL HOST & MICROBE (2017)

Add to Collection
Article Engineering, Biomedical

Resveratrol prevents alveolar bone loss in an experimental rat model of periodontitis

Govinda Bhattarai et al.

ACTA BIOMATERIALIA (2016)

Add to Collection
Article Multidisciplinary Sciences

Advanced glycation end products (AGEs) promote melanogenesis through receptor for AGEs

Eun Jung Lee et al.

SCIENTIFIC REPORTS (2016)

Add to Collection
Article Biochemical Research Methods

HTSeq-a Python framework to work with high-throughput sequencing data

Simon Anders et al.

BIOINFORMATICS (2015)

Add to Collection
Review Pathology

Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue - a review

Nickolay Fedchenko et al.

DIAGNOSTIC PATHOLOGY (2014)

Add to Collection
Article Immunology

Regulated cell death and inflammation: an auto-amplification loop causes organ failure

Andreas Linkermann et al.

NATURE REVIEWS IMMUNOLOGY (2014)

Add to Collection
Article Chemistry, Medicinal

The IC50 Concept Revisited

Gary W. Caldwell et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2012)

Add to Collection
Article Dentistry, Oral Surgery & Medicine

N-acetylcysteine decreases alveolar bone loss on experimental periodontitis in streptozotocin-induced diabetic rats

H. Toker et al.

JOURNAL OF PERIODONTAL RESEARCH (2012)

Add to Collection
Webinars Posters Questions Hubs Funding Journals Papers Connect Collections Reviewers About Us FAQs Mobile App Privacy Policy Terms of Use
© Peeref 2019-2024. All rights reserved.