4.4 Article

Increased ENT2 expression and its association with altered purine metabolism in cell lines derived from different stages of colorectal cancer

Related references

Note: Only part of the references are listed.
Article Medicine, General & Internal

C1QBP regulates apoptosis of renal cell carcinoma via modulating xanthine dehydrogenase (XDH) mediated ROS generation

Yiting Wang et al.

Summary: C1QBP promotes the catabolism of hypoxanthine and enhances the apoptosis of RCC cells by modulating XDH-mediated ROS generation.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2022)

Article Pharmacology & Pharmacy

Metabolomic characterization of colorectal cancer cell lines highlighting stage-specific alterations during cancer progression

Hazwani Mohd Yusof et al.

Summary: Metabolomic study on different stages of colorectal cancer (CRC) cell lines revealed unique differential metabolites in each stage, contributing to a better understanding of the pathophysiology of CRC development and progression. The identification of stage-specific metabolites may have implications for the development of targeted treatment strategies for CRC.

BIOIMPACTS (2021)

Article Pharmacology & Pharmacy

Global metabolomics profiling of colorectal cancer in Malaysian patients

Nurul Azmir Amir Hashim et al.

Summary: The study identified distinguishing biomarkers for Malaysian CRC patients through serum metabolomics profiling, with 11 differential metabolites showing potential for 80% accuracy in differentiating CRC from normal samples. The most perturbed metabolic pathways in CRC were found to be purine, catecholamine, and amino acid metabolisms.

BIOIMPACTS (2021)

Article Biochemistry & Molecular Biology

HPLC reveals novel features of nucleoside and nucleobase homeostasis, nucleoside metabolism and nucleoside transport

Reema A. Altaweraqi et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2020)

Letter Public, Environmental & Occupational Health

Remdesivir as a possible therapeutic option for the COVID-19

Jaffar A. Al-Tawfiq et al.

TRAVEL MEDICINE AND INFECTIOUS DISEASE (2020)

Review Biotechnology & Applied Microbiology

Equilibrative Nucleoside Transporter 2: Properties and Physiological Roles

Safaa M. Naes et al.

BIOMED RESEARCH INTERNATIONAL (2020)

Review Biochemistry & Molecular Biology

Comprehensive review of targeted therapy for colorectal cancer

Yuan-Hong Xie et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

Review Pharmacology & Pharmacy

Unraveling 'The Cancer Genome Atlas' information on the role of SLC transporters in anticancer drug uptake

Ruba Al-Abdulla et al.

EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2019)

Article Biochemistry & Molecular Biology

Deoxypodophyllotoxin Exerts Anti-Cancer Effects on Colorectal Cancer Cells Through Induction of Apoptosis and Suppression of Tumorigenesis

Chathurika D. B. Gamage et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Food Science & Technology

Auriculasin-induced ROS causes prostate cancer cell death via induction of apoptosis

Hyun-Dong Cho et al.

FOOD AND CHEMICAL TOXICOLOGY (2018)

Review Pharmacology & Pharmacy

Emerging Roles of Nucleoside Transporters

Marcal Pastor-Anglada et al.

FRONTIERS IN PHARMACOLOGY (2018)

Review Immunology

Potential Mechanisms Connecting Purine Metabolism and Cancer Therapy

Jie Yin et al.

FRONTIERS IN IMMUNOLOGY (2018)

Review Biochemistry & Molecular Biology

Emerging Role of Purine Metabolizing Enzymes in Brain Function and Tumors

Mercedes Garcia-Gil et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Biochemistry & Molecular Biology

Extracellular purines, purinergic receptors and tumor growth

F. Di Virgilio et al.

ONCOGENE (2017)

Correction Oncology

Cancer metabolism: a therapeutic perspective (vol 14, pg 11, 2017)

Ubaldo E. Martinez-Outschoorn et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2017)

Review Biochemistry & Molecular Biology

A New View into the Regulation of Purine Metabolism: The Purinosome

Anthony M. Pedley et al.

TRENDS IN BIOCHEMICAL SCIENCES (2017)

Review Oncology

Xanthine oxidoreductase in cancer: more than adifferentiation marker

Maria Giulia Battelli et al.

CANCER MEDICINE (2016)

Review Geriatrics & Gerontology

Colorectal cancer development and advances in screening

Karen Simon

CLINICAL INTERVENTIONS IN AGING (2016)

Article Medicine, Research & Experimental

Effect of Hypoxanthine on Functional Activity of Nucleoside Transporters ENT1 and ENT2 in Caco-2 Polar Epithelial Intestinal Cells

N. V. Senyavina et al.

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2015)

Article Oncology

8-Oxo-7,8-dihydroguanine and uric acid as efficient predictors of survival in colon cancer patients

Tomasz Dziaman et al.

INTERNATIONAL JOURNAL OF CANCER (2014)

Article Biochemical Research Methods

Colorectal Cancer Detection Using Targeted Serum Metabolic Profiling

Jiangjiang Zhu et al.

JOURNAL OF PROTEOME RESEARCH (2014)

Review Biochemistry & Molecular Biology

Nucleoside transporters in the purinome

Alexandre dos Santos-Rodrigues et al.

NEUROCHEMISTRY INTERNATIONAL (2014)

Review Biochemistry & Molecular Biology

The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29

James D. Young et al.

MOLECULAR ASPECTS OF MEDICINE (2013)

Review Biotechnology & Applied Microbiology

Cell Metabolomics

Aihua Zhang et al.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2013)

Review Oncology

Contribution of uric acid to cancer risk, recurrence, and mortality

Mehdi A. Fini et al.

CLINICAL AND TRANSLATIONAL MEDICINE (2012)

Article Biochemistry & Molecular Biology

Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development

Assaf C. Bester et al.

Article Medical Laboratory Technology

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

Stephen A. Bustin et al.

CLINICAL CHEMISTRY (2009)

Review Biotechnology & Applied Microbiology

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

Dunyaporn Trachootham et al.

NATURE REVIEWS DRUG DISCOVERY (2009)

Article Biochemical Research Methods

Analyzing real-time PCR data by the comparative C-T method

Thomas D. Schmittgen et al.

NATURE PROTOCOLS (2008)

Article Oncology

Reactive oxygen species: A breath of life or death?

John P. Fruehauf et al.

CLINICAL CANCER RESEARCH (2007)