Related references
Note: Only part of the references are listed.
Review
Cardiac & Cardiovascular Systems
Steffen E. Petersen et al.
Summary: This report summarizes the evidence concerning the etiology, pathophysiology, and clinical relevance of excessive trabeculation. Current evidence does not support the formation of compact myocardium from noncompacted myocardium, nor the arrest of this process to result in noncompaction. Excessive trabeculation is observed in healthy individuals, as well as in association with pregnancy, athletic activity, and cardiac diseases of various origins. The prognostic role of excessive trabeculation in adults has not been shown to be independent of other myocardial disease. Neonates and children with excessive trabeculation may have genetic and neuromuscular disorders.
JACC-CARDIOVASCULAR IMAGING
(2023)
Review
Cardiac & Cardiovascular Systems
Steffen E. Petersen et al.
Summary: Excessive trabeculation, or noncompacted myocardium, is observed across all age groups, but current evidence does not support its conversion into compact myocardium or the halt of this process leading to noncompaction. Excessive trabeculation is commonly seen in imaging studies in healthy individuals, as well as in association with various cardiac diseases and conditions. Further follow-up is usually not needed for adults with incidentally noted excessive trabeculation based on trabecular pattern alone. However, caution should be exercised when excessive trabeculation is observed in neonates and children, as it may be associated with genetic and neuromuscular disorders. The prognostic role of excessive trabeculation in adults has not been shown to be independent of other myocardial diseases.
JACC-CARDIOVASCULAR IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shiqin Yu et al.
Summary: This study revealed that LV systolic dysfunction could be early detected in LVNC patients with normal LVEF using cardiac MRI feature tracking, and it was associated with the complexity of excessive trabeculation assessed by FD.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jie Wang et al.
Summary: This study explored the prognostic value of myocardial trabecular complexity in patients with HCM using fractal analysis and found that the left ventricular apical fractal dimension was an independent predictor of the primary and secondary end points in these patients.
Article
Cardiac & Cardiovascular Systems
Marie Cambon-Viala et al.
Summary: The study revealed the importance of genotype-phenotype relationship in patients with LVNC, particularly in those with ion channel gene mutations. Patients with ion channel gene mutations presented higher LV ejection fraction and more frequent biventricular noncompaction compared to those without mutations, highlighting the significance of identifying causative mutations for genetic counseling and management of the disease.
JOURNAL OF CARDIAC FAILURE
(2021)
Article
Cardiac & Cardiovascular Systems
Alexander Ivanov et al.
CIRCULATION-CARDIOVASCULAR IMAGING
(2017)
