Porcine circovirus 3 (PCV-3) variability: Is it in the virus or in the classification criteria?

Article Virology

Molecular detection and phylogenetic analysis of porcine circovirus type 3 in Tibetan pigs on the Qinghai-Tibet Plateau of China

Yangyang Pan et al.

Summary: The study revealed the prevalence of PCV3 in Tibetan pigs in high-altitude regions of China, with higher rates of PCV3a and PCV3b subtypes in samples from diarrheic pigs. Genetic analysis showed high nucleotide identity in Cap protein sequences of different PCV3 strains, with specific amino acid sequence mutations identified in different subtypes. Further research on the evolution and pathogenicity mechanisms of PCV3 in Tibetan pigs living in this unique environment is recommended.

VIROLOGY JOURNAL (2022)

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Article Virology

Epidemiological and genetic characteristics of porcine circovirus 3 in 15 provinces and municipalities of China between 2016 and 2020

Xugang Ku et al.

Summary: This study investigated the epidemiology and genotype distribution of PCV3 in Chinese pig farms. The majority of PCV3 isolates belonged to genotype PCV3c, and three sites undergoing positive selection were found, which may be related to the pig's immune system.

VIROLOGY JOURNAL (2022)

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Article Virology