☆ 4.7 Article

Isolation and identification of two novel pseudorabies viruses with natural recombination or TK gene deletion in China

VETERINARY MICROBIOLOGY (2023)

Related references

Note: Only part of the references are listed.

Review Virology

The Epidemiology and Variation in Pseudorabies Virus: A Continuing Challenge to Pigs and Humans

Qingyun Liu et al.

Summary: Pseudorabies virus (PRV) is a virus that can infect most mammals and causes economic losses in the pig industry. It can lead to severe symptoms and high mortality, and there has been an increasing number of human cases reported in China. This review provides an overview of the global prevalence and variation of PRV, as well as the vaccines and diagnostic methods used for control. While control programs have been implemented in many countries, PRV is still globally epizootic and an important pathogen for pigs.

VIRUSES-BASEL (2022)

Add to Collection

Article Veterinary Sciences

Same Dosages of rPRV/XJ5-gI-/gE-/TK- Prototype Vaccine or Bartha-K61 Vaccine Similarly Protects Growing Pigs Against Lethal Challenge of Emerging vPRV/XJ-5 Strain

Qinghai Ren et al.

Summary: The immune effectiveness of Bartha-K61 vaccine and rPRV/XJ5-gI(-)/gE(-)/TK- prototype vaccine against vPRV/XJ-5 was evaluated in growing pigs. The results demonstrated that both vaccines provided parallel efficacy in pigs against the lethal challenge with the XJ-5 strain of vPRV.

FRONTIERS IN VETERINARY SCIENCE (2022)

Add to Collection

Article Virology

Construction and characterization of a full-length infectious clone of Getah virus in vivo

Tongwei Ren et al.

Summary: In this study, an inverse genetic system for GETV was successfully established, which provides a valuable tool for studying the virus life cycle and developing genetically engineered GETVs as vectors. The recombinant virus showed milder pathogenicity in mice.

VIROLOGICA SINICA (2022)

Add to Collection

Article Veterinary Sciences

Bartha-K61 vaccine protects nursery pigs against challenge with novel european and asian strains of suid herpesvirus 1

Konstantinos Papageorgiou et al.

Summary: This study investigated the pathogenicity of two strains of Suid herpesvirus 1 (SuHV1), the Greek strain Hercules and the Chinese strain HeN1. The results showed that the HeN1 strain was more virulent in unvaccinated pigs, but after vaccination with the Bartha-K61 strain, both strains were equally protected.

VETERINARY RESEARCH (2022)

Add to Collection

Article Immunology

A Novel Human Acute Encephalitis Caused by Pseudorabies Virus Variant Strain

Qingyun Liu et al.

Summary: This study reported the first isolation of a PRV strain from an acute human encephalitis case, showing close phylogenetic relationships and similar etiological characteristics to Chinese PRV variant strains, suggesting the significant risk of PRV transmission from pigs to humans.

CLINICAL INFECTIOUS DISEASES (2021)

Add to Collection

Article Infectious Diseases

Emergence of a novel pathogenic recombinant virus from Bartha vaccine and variant pseudorabies virus in China

Zongyi Bo et al.

Summary: Two PRV variants, named JSY7 and JSY13 strains, were isolated from a Bartha-K61-vaccinated swine farm. These variants showed different cytopathic effects and plaque sizes, but had the same Aspartate insertions in the gE protein. Genomic analysis clustered JSY7 and JSY13 strains in the same clade with other PRV isolates in China. The study also revealed evidence of genomic recombination between the JSY13 strain and the Bartha and JSY7 strains, highlighting the importance of this process in PRV evolution and virulence.

TRANSBOUNDARY AND EMERGING DISEASES (2021)

Add to Collection

Review Virology

Current Status and Challenge of Pseudorabies Virus Infection in China

Lei Tan et al.

Summary: PR, a highly infectious disease caused by PRV, has been prevalent in Chinese pig industry, posing significant economic losses. Despite efforts in diagnostic approaches and vaccine development, PR remains a major concern in the swine industry in China.

VIROLOGICA SINICA (2021)

Add to Collection

Article Veterinary Sciences

Efficacy of the Bartha-K61 vaccine and a gE-/gI-/T- prototype vaccine against variant porcine pseudorabies virus (vPRV) in piglets with sublethal challenge of vPRV

Jin Wang et al.

RESEARCH IN VETERINARY SCIENCE (2020)

Add to Collection

Article Infectious Diseases

Genetic evolution analysis of novel recombinant pseudorabies virus strain in Sichuan, China

Jianbo Huang et al.

TRANSBOUNDARY AND EMERGING DISEASES (2020)

Add to Collection

Article Biochemical Research Methods

Construction and immunogenicity of a gE/gI/TK-deleted PRV based on porcine pseudorabies virus variant

Yu Zhao et al.

MOLECULAR AND CELLULAR PROBES (2020)

Add to Collection

Article Microbiology

Immunogenicity and protective efficacy induced by an mRNA vaccine encoding gD antigen against pseudorabies virus infection

Ziyi Jiang et al.

VETERINARY MICROBIOLOGY (2020)

Add to Collection

Article Virology

Genome Characteristics and Evolution of Pseudorabies Virus Strains in Eastern China from 2017 to 2019

Xiaofeng Zhai et al.

VIROLOGICA SINICA (2019)

Add to Collection

Article Veterinary Sciences

A gD&gC-substituted pseudorabies virus vaccine strain provides complete clinical protection and is helpful to prevent virus shedding against challenge by a Chinese pseudorabies variant

Chuanjian Zhang et al.

BMC VETERINARY RESEARCH (2019)

Add to Collection

Article Immunology

Interspecies Transmission, Genetic Diversity, and Evolutionary Dynamics of Pseudorabies Virus

Wanting He et al.

JOURNAL OF INFECTIOUS DISEASES (2019)

Add to Collection

Article Infectious Diseases

Epidemiological investigation of pseudorabies in Shandong Province from 2013 to 2016

J. Gu et al.

TRANSBOUNDARY AND EMERGING DISEASES (2018)

Add to Collection

Article Veterinary Sciences

Safety and immunogenicity of an attenuated Chinese pseudorabies variant by dual deletion of TK&gE genes

Jichun Wang et al.

BMC VETERINARY RESEARCH (2018)

Add to Collection

Article Immunology

Bartha-k61 vaccine protects growing pigs against challenge with an emerging variant pseudorabies virus

Jinzhu Zhou et al.

VACCINE (2017)

Add to Collection

Article Microbiology

Variations in glycoprotein B contribute to immunogenic difference between PRV variant JS-2012 and Bartha-K61

Zhi-qing Yu et al.

VETERINARY MICROBIOLOGY (2017)

Add to Collection

Article Virology

Genomic analyses reveal that partial sequence of an earlier pseudorabies virus in China is originated from a Bartha-vaccine-like strain

Chao Ye et al.

VIROLOGY (2016)

Add to Collection

Article Microbiology

Emergence of a Pseudorabies virus variant with increased virulence to piglets

Wu Tong et al.

VETERINARY MICROBIOLOGY (2015)

Add to Collection

Article Immunology

A novel gE-deleted pseudorabies virus (PRV) provides rapid and complete protection from lethal challenge with the PRV variant emerging in Bartha-K61-vaccinated swine population in China

Chun-Hua Wang et al.

VACCINE (2014)

Add to Collection

Article Microbiology

Pathogenicity and genomic characterization of a pseudorabies virus variant isolated from Bartha-K61-vaccinated swine population in China

Yuzi Luo et al.

VETERINARY MICROBIOLOGY (2014)

Add to Collection

Article Immunology

Pathogenic Pseudorabies Virus, China, 2012

Xiuling Yu et al.

EMERGING INFECTIOUS DISEASES (2014)

Add to Collection

Article Immunology

Pseudorabies Virus Variant in Bartha-K61-Vaccinated Pigs, China, 2012

Tong-Qing An et al.

EMERGING INFECTIOUS DISEASES (2013)

Add to Collection

Review Microbiology

Molecular biololgy of pseudorabies virus: Impact on neurovirology and veterinary medicine

LE Pomeranz et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2005)

Add to Collection

Article Virology

Complete, annotated sequence of the pseudorabies virus genome

BG Klupp et al.

JOURNAL OF VIROLOGY (2004)

Add to Collection

© Peeref 2019-2024. All rights reserved.